The MeCP2E1/E2-BDNF-miR132 Homeostasis Regulatory Network Is Region-Dependent in the Human Brain and Is Impaired in Rett Syndrome Patients

Differential brain region‐specific expression of MeCP2 and BDNF in Rett Syndrome patients: a distinct grey‐white matter variation

(2020) S. Pejhan et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Genome-Wide Transcriptome Landscape of Embryonic Brain-Derived Neural Stem Cells Exposed to Alcohol with Strain-Specific Cross-Examination in BL6 and CD1 Mice

(2019) Wayne Xu et al.   Scientific Reports

DNA Methylation Contributes to the Differential Expression Levels of Mecp2 in Male Mice Neurons and Astrocytes

(2019) Vichithra R.B. Liyanage et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Simvastatin Induces Apoptosis in Medulloblastoma Brain Tumor Cells via Mevalonate Cascade Prenylation Substrates

(2019) Kimia Sheikholeslami et al.   Cancers

Chronic Ethanol Exposure Alters DNA Methylation in Neural Stem Cells: Role of Mouse Strain and Sex

(2019) Shayan Amiri et al.   MOLECULAR NEUROBIOLOGY

The Molecular Basis of MeCP2 Function in the Brain

(2019) Rebekah Tillotson et al.   JOURNAL OF MOLECULAR BIOLOGY

MeCP2-E1 isoform is a dynamically expressed, weakly DNA-bound protein with different protein and DNA interactions compared to MeCP2-E2

(2019) Alexia Martínez de Paz et al.   Epigenetics & Chromatin

Altered inflammasome machinery as a key player in the perpetuation of Rett syndrome oxinflammation

(2019) Alessandra Pecorelli et al.   Redox Biology

MeCP2_e2 partially compensates for lack of MeCP2_e1: A male case of Rett syndrome

(2019) Ryo Takeguchi et al.   Molecular Genetics & Genomic Medicine

U6 can be used as a housekeeping gene for urinary sediment miRNA studies of IgA nephropathy

(2018) Zhi-Yu Duan et al.   Scientific Reports

MeCP2 isoform e1 mutant mice recapitulate motor and metabolic phenotypes of Rett syndrome

(2018) Annie Vogel Ciernia et al.   HUMAN MOLECULAR GENETICS

MECP2 Mutation Interrupts Nucleolin–mTOR–P70S6K Signaling in Rett Syndrome Patients

(2018) Carl O. Olson et al.   Frontiers in Genetics

MeCP2_E1 N-terminal modifications affect its degradation rate and are disrupted by the Ala2Val Rett mutation

(2017) Taimoor I Sheikh et al.   HUMAN MOLECULAR GENETICS

RettBASE: Rett syndrome database update

(2017) Rahul Krishnaraj et al.   HUMAN MUTATION

Choline Ameliorates Disease Phenotypes in Human iPSC Models of Rett Syndrome

(2016) Eunice W. M. Chin et al.   NEUROMOLECULAR MEDICINE

Repetitive acute intermittent hypoxia increases growth/neurotrophic factor expression in non-respiratory motor neurons

(2016) I. Satriotomo et al.   NEUROSCIENCE

Ethanol deregulates Mecp2/MeCP2 in differentiating neural stem cells via interplay between 5-methylcytosine and 5-hydroxymethylcytosine at the Mecp2 regulatory elements

(2015) Vichithra Rasangi Batuwita Liyanage et al.   EXPERIMENTAL NEUROLOGY

MeCP2 controls hippocampal brain-derived neurotrophic factor expression via homeostatic interactions with microRNA-132 in rats with depression

(2015) MEILEI SU et al.   Molecular Medicine Reports

Role of Hypoxia-Induced Brain Derived Neurotrophic Factor in Human Pulmonary Artery Smooth Muscle

(2015) William Hartman et al.   PLoS One

MECP2 Is a Frequently Amplified Oncogene with a Novel Epigenetic Mechanism That Mimics the Role of Activated RAS in Malignancy

(2015) M. Neupane et al.   Cancer Discovery

Rett Syndrome and MeCP2

(2014) Vichithra R. B. Liyanage et al.   NEUROMOLECULAR MEDICINE

Identification and Validation of miRNAs as Endogenous Controls for RQ-PCR in Blood Specimens for Breast Cancer Studies

(2014) Ailbhe M. McDermott et al.   PLoS One

Brain Region-Specific Expression of MeCP2 Isoforms Correlates with DNA Methylation within Mecp2 Regulatory Elements

(2014) Carl O. Olson et al.   PLoS One

Dynamic expression of MEIS1 homeoprotein in E14.5 forebrain and differentiated forebrain-derived neural stem cells

(2013) Benjamin A. Barber et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

Mice with an isoform-ablating Mecp2 exon 1 mutation recapitulate the neurologic deficits of Rett syndrome

(2013) Dag H. Yasui et al.   HUMAN MOLECULAR GENETICS

Decitabine alters the expression of Mecp2 isoforms via dynamic DNA methylation at the Mecp2 regulatory elements in neural stem cells

(2013) Vichithra R B Liyanage et al.   Molecular Autism

Methyl CpG-binding Protein Isoform MeCP2_e2 Is Dispensable for Rett Syndrome Phenotypes but Essential for Embryo Viability and Placenta Development

(2012) Masayuki Itoh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel MeCP2 Isoform-Specific Antibody Reveals the Endogenous MeCP2E1 Expression in Murine Brain, Primary Neurons and Astrocytes

(2012) Robby M. Zachariah et al.   PLoS One

Disease Modeling Using Embryonic Stem Cells: MeCP2 Regulates Nuclear Size and RNA Synthesis in Neurons

(2012) Morteza Yazdani et al.   STEM CELLS

Linking Epigenetics to Human Disease and Rett Syndrome: The Emerging Novel and Challenging Concepts in MeCP2 Research

(2012) Robby Mathew Zachariah et al.   NEURAL PLASTICITY

Transgenic complementation of MeCP2 deficiency: phenotypic rescue of Mecp2-null mice by isoform-specific transgenes

(2011) Bredford Kerr et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells

(2010) Maria C.N. Marchetto et al.   CELL

Epigenetic control

(2009) Geneviève P. Delcuve et al.   JOURNAL OF CELLULAR PHYSIOLOGY

MECP2 Isoform-Specific Vectors with Regulated Expression for Rett Syndrome Gene Therapy

(2009) Mojgan Rastegar et al.   PLoS One

Distinct subcellular localization of BDNF transcripts in cultured hypothalamic neurons and modification by neuronal activation

(2008) Esteban Enrique Aliaga et al.   JOURNAL OF NEURAL TRANSMISSION

Specific mutations in Methyl-CpG-Binding Protein 2 confer different severity in Rett syndrome

(2008) J. L. Neul et al.   NEUROLOGY

MECP2 genomic structure and function: insights from ENCODE

(2008) J. Singh et al.   NUCLEIC ACIDS RESEARCH