Simvastatin Induces Apoptosis in Medulloblastoma Brain Tumor Cells via Mevalonate Cascade Prenylation Substrates
出版年份 2019 全文链接
标题
Simvastatin Induces Apoptosis in Medulloblastoma Brain Tumor Cells via Mevalonate Cascade Prenylation Substrates
作者
关键词
-
出版物
Cancers
Volume 11, Issue 7, Pages 994
出版商
MDPI AG
发表日期
2019-07-17
DOI
10.3390/cancers11070994
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Genome-Wide Transcriptome Landscape of Embryonic Brain-Derived Neural Stem Cells Exposed to Alcohol with Strain-Specific Cross-Examination in BL6 and CD1 Mice
- (2019) Wayne Xu et al. Scientific Reports
- Targeting cholesterol metabolism in glioblastoma: a new therapeutic approach in cancer therapy
- (2019) Leila Pirmoradi et al. JOURNAL OF INVESTIGATIVE MEDICINE
- Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes
- (2019) Tanvi Sharma et al. ACTA NEUROPATHOLOGICA
- DNA Methylation Contributes to the Differential Expression Levels of Mecp2 in Male Mice Neurons and Astrocytes
- (2019) Vichithra R.B. Liyanage et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Statins Synergize with Hedgehog Pathway Inhibitors for Treatment of Medulloblastoma
- (2018) Renata E. Gordon et al. CLINICAL CANCER RESEARCH
- Targeting mTOR as a Therapeutic Approach in Medulloblastoma
- (2018) Juncal Aldaregia et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Surgical treatment of intramedullary spinal metastasis in medulloblastoma: case report and review of literature
- (2018) Anshit Goyal et al. World Neurosurgery
- Statins: a new approach to combat temozolomide chemoresistance in glioblastoma
- (2018) Shahla Shojaei et al. JOURNAL OF INVESTIGATIVE MEDICINE
- MECP2 Mutation Interrupts Nucleolin–mTOR–P70S6K Signaling in Rett Syndrome Patients
- (2018) Carl O. Olson et al. Frontiers in Genetics
- Medulloblastoma: From Myth to Molecular
- (2017) Vijay Ramaswamy et al. JOURNAL OF CLINICAL ONCOLOGY
- Demographics, patterns of care, and survival in pediatric medulloblastoma
- (2017) Emily V. Dressler et al. JOURNAL OF NEURO-ONCOLOGY
- Medulloblastoma: Molecular Classification-Based Personal Therapeutics
- (2017) Tenley C. Archer et al. Neurotherapeutics
- Differences of statin activity in 2D and 3D pancreatic cancer cell cultures
- (2017) Miglė Paškevičiūtė et al. Drug Design Development and Therapy
- Mevalonate Cascade Inhibition by Simvastatin Induces the Intrinsic Apoptosis Pathway via Depletion of Isoprenoids in Tumor Cells
- (2017) Javad Alizadeh et al. Scientific Reports
- Editorial: New Insights into a Classical Pathway: Key Roles of the Mevalonate Cascade in Different Diseases (Part II)
- (2017) Amir A. Zeki et al. Current Molecular Pharmacology
- Clinical Outcomes Among Children With Standard-Risk Medulloblastoma Treated With Proton and Photon Radiation Therapy: A Comparison of Disease Control and Overall Survival
- (2016) Bree R. Eaton et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Medulloblastoma
- (2016) Nathan E. Millard et al. JOURNAL OF CHILD NEUROLOGY
- Statin induces apoptosis of human colon cancer cells and downregulation of insulin-like growth factor 1 receptor via proapoptotic ERK activation
- (2016) HYUN JOO JANG et al. Oncology Letters
- Caspase-Dependent and Caspase-Independent Pathways Are Involved in Cadmium-Induced Apoptosis in Primary Rat Proximal Tubular Cell Culture
- (2016) Gang Liu et al. PLoS One
- Factors affecting survival of medulloblastoma in children: the changing concept of management
- (2015) Tai-Tong Wong et al. CHILDS NERVOUS SYSTEM
- Ethanol deregulates Mecp2/MeCP2 in differentiating neural stem cells via interplay between 5-methylcytosine and 5-hydroxymethylcytosine at the Mecp2 regulatory elements
- (2015) Vichithra Rasangi Batuwita Liyanage et al. EXPERIMENTAL NEUROLOGY
- The effect of statins on cancer cells—review
- (2015) Lucyna Matusewicz et al. TUMOR BIOLOGY
- Cellular commitment in the developing cerebellum
- (2015) Hassan Marzban et al. Frontiers in Cellular Neuroscience
- Early downregulation of Mcl-1 regulates apoptosis triggered by cardiac glycoside UNBS1450
- (2015) C Cerella et al. Cell Death & Disease
- Simvastatin-induced breast cancer cell death and deactivation of PI3K/Akt and MAPK/ERK signalling are reversed by metabolic products of the mevalonate pathway
- (2015) Tingting Wang et al. Oncotarget
- Airway mesenchymal cell death by mevalonate cascade inhibition: Integration of autophagy, unfolded protein response and apoptosis focusing on Bcl2 family proteins
- (2014) Saeid Ghavami et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Targeting the mevalonate cascade as a new therapeutic approach in heart disease, cancer and pulmonary disease
- (2014) Behzad Yeganeh et al. PHARMACOLOGY & THERAPEUTICS
- Brain Region-Specific Expression of MeCP2 Isoforms Correlates with DNA Methylation within Mecp2 Regulatory Elements
- (2014) Carl O. Olson et al. PLoS One
- Dynamic expression of MEIS1 homeoprotein in E14.5 forebrain and differentiated forebrain-derived neural stem cells
- (2013) Benjamin A. Barber et al. ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER
- Lovastatin-induced apoptosis is mediated by activating transcription factor 3 and enhanced in combination with salubrinal
- (2013) Nima Niknejad et al. INTERNATIONAL JOURNAL OF CANCER
- Direct Interaction of Bax and Bak Proteins with Bcl-2 Homology Domain 3 (BH3)-only Proteins in Living Cells Revealed by Fluorescence Complementation
- (2013) Laura Vela et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Simvastatin Inhibits Proliferation and Induces Apoptosis in Human Lung Cancer Cells
- (2013) Xiaofeng Yu et al. ONCOLOGY RESEARCH
- Decitabine alters the expression of Mecp2 isoforms via dynamic DNA methylation at the Mecp2 regulatory elements in neural stem cells
- (2013) Vichithra R B Liyanage et al. Molecular Autism
- Statin Use and Reduced Cancer-Related Mortality
- (2012) Sune F. Nielsen et al. NEW ENGLAND JOURNAL OF MEDICINE
- Novel MeCP2 Isoform-Specific Antibody Reveals the Endogenous MeCP2E1 Expression in Murine Brain, Primary Neurons and Astrocytes
- (2012) Robby M. Zachariah et al. PLoS One
- Apoptosis, autophagy and ER stress in mevalonate cascade inhibition-induced cell death of human atrial fibroblasts
- (2012) S Ghavami et al. Cell Death & Disease
- Simvastatin inhibits cancer cell growth by inducing apoptosis correlated to activation of Bax and down-regulation of BCL-2 gene expression
- (2011) CARMINE SPAMPANATO et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma
- (2011) Masashi Yanae et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Mevalonate Cascade Regulation of Airway Mesenchymal Cell Autophagy and Apoptosis: A Dual Role for p53
- (2011) Saeid Ghavami et al. PLoS One
- Induction of Caspase-3-Dependent Apoptosis in Human Leukemia HL-60 Cells by δ-Elemene
- (2011) Jun YING et al. YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN
- Statin-triggered cell death in primary human lung mesenchymal cells involves p53-PUMA and release of Smac and Omi but not cytochrome c
- (2010) Saeid Ghavami et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Mcl-1 downregulation by pro-inflammatory cytokines and palmitate is an early event contributing to β-cell apoptosis
- (2010) F Allagnat et al. CELL DEATH AND DIFFERENTIATION
- Simvastatin Stimulates Production of the Antiapoptotic Protein Bcl-2 via Endothelin-1 and NFATc3 in SH-SY5Y Cells
- (2010) Tammy A. Butterick et al. MOLECULAR NEUROBIOLOGY
- Statin-induced autophagy by inhibition of geranylgeranyl biosynthesis in prostate cancer PC3 cells
- (2010) Ankur Parikh et al. PROSTATE
- Statin-Induced Inhibition of MCF-7 Breast Cancer Cell Proliferation is Related to Cell Cycle Arrest and Apoptotic and Necrotic Cell Death Mediated by an Enhanced Oxidative Stress
- (2008) Claudia A. Sánchez et al. CANCER INVESTIGATION
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search