Rett Syndrome and MeCP2

Brain Region-Specific Expression of MeCP2 Isoforms Correlates with DNA Methylation within Mecp2 Regulatory Elements

(2014) Carl O. Olson et al.   PLoS One

Mild Overexpression of Mecp2 in Mice Causes a Higher Susceptibility toward Seizures

(2013) Chiranjeevi Bodda et al.   AMERICAN JOURNAL OF PATHOLOGY

Dynamic expression of MEIS1 homeoprotein in E14.5 forebrain and differentiated forebrain-derived neural stem cells

(2013) Benjamin A. Barber et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

Methylation-Dependent and -Independent Genomic Targeting Principles of the MBD Protein Family

(2013) Tuncay Baubec et al.   CELL

An AT-Hook Domain in MeCP2 Determines the Clinical Course of Rett Syndrome and Related Disorders

(2013) Steven Andrew Baker et al.   CELL

Global Transcriptional and Translational Repression in Human-Embryonic-Stem-Cell-Derived Rett Syndrome Neurons

(2013) Yun Li et al.   Cell Stem Cell

Human-specific regulation of MeCP2 levels in fetal brains by microRNA miR-483-5p

(2013) K. Han et al.   GENES & DEVELOPMENT

Expression of DNA Methyltransferases in Breast Cancer Patients and to Analyze the Effect of Natural Compounds on DNA Methyltransferases and Associated Proteins

(2013) Sameer Mirza et al.   Journal of Breast Cancer

Oligodendrocyte Lineage Cells Contribute Unique Features to Rett Syndrome Neuropathology

(2013) M. V. C. Nguyen et al.   JOURNAL OF NEUROSCIENCE

Moderate Prenatal Alcohol Exposure Reduces Plasticity and Alters NMDA Receptor Subunit Composition in the Dentate Gyrus

(2013) M. L. Brady et al.   JOURNAL OF NEUROSCIENCE

Systemic Delivery of MeCP2 Rescues Behavioral and Cellular Deficits in Female Mouse Models of Rett Syndrome

(2013) S. K. Garg et al.   JOURNAL OF NEUROSCIENCE

Gene expression of epigenetic regulatory factors related to primary silencing mechanism is less susceptible to lower doses of bisphenol A in embryonic hypothalamic cells

(2013) Katsuhiko Warita et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor

(2013) Matthew J Lyst et al.   NATURE NEUROSCIENCE

Neuronal morphology in MeCP2 mouse models is intrinsically variable and depends on age, cell type, and Mecp2 mutation

(2013) I-Ting J. Wang et al.   NEUROBIOLOGY OF DISEASE

Effects of Ethanol Exposure During Early Pregnancy in Hyperactive, Inattentive and Impulsive Behaviors and MeCP2 Expression in Rodent Offspring

(2013) Pitna Kim et al.   NEUROCHEMICAL RESEARCH

Impaired in vivo binding of MeCP2 to chromatin in the absence of its DNA methyl-binding domain

(2013) D. P. Stuss et al.   NUCLEIC ACIDS RESEARCH

A synonymous change, p.Gly16Gly in MECP2 Exon 1, causes a cryptic splice event in a Rett Syndrome patient

(2013) Taimoor I Sheikh et al.   Orphanet Journal of Rare Diseases

DNA Methylation Program in Developing Hippocampus and Its Alteration by Alcohol

(2013) Yuanyuan Chen et al.   PLoS One

Vascular Dysfunction in a Mouse Model of Rett Syndrome and Effects of Curcumin Treatment

(2013) Anna Panighini et al.   PLoS One

Multiple-to-Multiple Relationships between MicroRNAs and Target Genes in Gastric Cancer

(2013) Yutaka Hashimoto et al.   PLoS One

Comparison of Genomic and Epigenomic Expression in Monozygotic Twins Discordant for Rett Syndrome

(2013) Miyake Kunio et al.   PLoS One

Dysregulation of the long non-coding RNA transcriptome in a Rett syndrome mouse model

(2013) Paolo Petazzi et al.   RNA Biology

DNA Methylation in Cancer: A Gene Silencing Mechanism and the Clinical Potential of Its Biomarkers

(2013) Shinichi Fukushige et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

The first mecp2-null zebrafish model shows altered motor behaviors

(2013) Thomas Pietri et al.   Frontiers in Neural Circuits

MeCP2 modulates gene expression pathways in astrocytes

(2013) Dag H Yasui et al.   Molecular Autism

Decitabine alters the expression of Mecp2 isoforms via dynamic DNA methylation at the Mecp2 regulatory elements in neural stem cells

(2013) Vichithra R B Liyanage et al.   Molecular Autism

The Effects of Maternal Separation on Adult Methamphetamine Self-Administration, Extinction, Reinstatement, and MeCP2 Immunoreactivity in the Nucleus Accumbens

(2013) Candace R. Lewis et al.   Frontiers in Psychiatry

The Behavioral Phenotype inMECP2Duplication Syndrome: A Comparison With Idiopathic Autism

(2012) Sarika U. Peters et al.   Autism Research

A case report of Chinese brothers with inherited MECP2-containing duplication: autism and intellectual disability, but not seizures or respiratory infections

(2012) Xiu Xu et al.   BMC Medical Genetics

Epigenetic Regulation by Z-DNA Silencer Function Controls Cancer-Associated ADAM-12 Expression in Breast Cancer: Cross-talk between MeCP2 and NF1 Transcription Factor Family

(2012) B. K. Ray et al.   CANCER RESEARCH

MeCP2 Binds to 5hmC Enriched within Active Genes and Accessible Chromatin in the Nervous System

(2012) Marian Mellén et al.   CELL

The expression patterns and correlations of claudin-6, methy-CpG binding protein 2, DNA methyltransferase 1, histone deacetylase 1, acetyl-histone H3 and acetyl-histone H4 and their clinicopathological significance in breast invasive ductal carcinomas

(2012) Xiaoming Xu et al.   Diagnostic Pathology

SIRT1-mediated deacetylation of MeCP2 contributes to BDNF expression

(2012) Loredana Zocchi et al.   Epigenetics

A two-stage association study identifies methyl-CpG-binding domain protein 2 gene polymorphisms as candidates for breast cancer susceptibility

(2012) Yadav Sapkota et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Regional MeCP2 expression levels in the female MeCP2-deficient mouse brain correlate with specific behavioral impairments

(2012) Robert G. Wither et al.   EXPERIMENTAL NEUROLOGY

Partial rescue of Rett syndrome by ω-3 polyunsaturated fatty acids (PUFAs) oil

(2012) Claudio De Felice et al.   Genes and Nutrition

Nuclear Calcium Signaling Controls Methyl-CpG-binding Protein 2 (MeCP2) Phosphorylation on Serine 421 following Synaptic Activity

(2012) Bettina Buchthal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Methyl CpG-binding Protein Isoform MeCP2_e2 Is Dispensable for Rett Syndrome Phenotypes but Essential for Embryo Viability and Placenta Development

(2012) Masayuki Itoh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of MeCP2 at Ser421 Contributes to Chronic Antidepressant Action

(2012) A. N. Hutchinson et al.   JOURNAL OF NEUROSCIENCE

A Mouse Model for MeCP2 Duplication Syndrome: MeCP2 Overexpression Impairs Learning and Memory and Synaptic Transmission

(2012) E. S. Na et al.   JOURNAL OF NEUROSCIENCE

MeCP2 Phosphorylation Is Required for Modulating Synaptic Scaling through mGluR5

(2012) X. Zhong et al.   JOURNAL OF NEUROSCIENCE

MeCP2 Is Critical for Maintaining Mature Neuronal Networks and Global Brain Anatomy during Late Stages of Postnatal Brain Development and in the Mature Adult Brain

(2012) M. V. C. Nguyen et al.   JOURNAL OF NEUROSCIENCE

Isoform-Specific Toxicity of Mecp2 in Postmitotic Neurons: Suppression of Neurotoxicity by FoxG1

(2012) S. G. Dastidar et al.   JOURNAL OF NEUROSCIENCE

The Rett Syndrome Protein MeCP2 Regulates Synaptic Scaling

(2012) Z. Qiu et al.   JOURNAL OF NEUROSCIENCE

Gastrointestinal and Nutritional Problems Occur Frequently Throughout Life in Girls and Women With Rett Syndrome

(2012) Kathleen J. Motil et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Phosphorylation of Distinct Sites in MeCP2 Modifies Cofactor Associations and the Dynamics of Transcriptional Regulation

(2012) M. L. Gonzales et al.   MOLECULAR AND CELLULAR BIOLOGY

Reduced expression of MECP2 affects cell commitment and maintenance in neurons by triggering senescence: new perspective for Rett syndrome

(2012) Tiziana Squillaro et al.   MOLECULAR BIOLOGY OF THE CELL

The Expression of Spinal Methyl-CpG-Binding Protein 2, DNA Methyltransferases and Histone Deacetylases is Modulated in Persistent Pain States

(2012) Keri K Tochiki et al.   Molecular Pain

Wild-type microglia arrest pathology in a mouse model of Rett syndrome

(2012) Noël C. Derecki et al.   NATURE

Rett syndrome treatment in mouse models: Searching for effective targets and strategies

(2012) Laura Ricceri et al.   NEUROPHARMACOLOGY

The Impact of MeCP2 Loss- or Gain-of-Function on Synaptic Plasticity

(2012) Elisa S Na et al.   NEUROPSYCHOPHARMACOLOGY

Maternal separation and proclivity for ethanol intake: A potential role of the endocannabinoid system in rats

(2012) A. Romano-López et al.   NEUROSCIENCE

Alterations of Gene Expression and Glutamate Clearance in Astrocytes Derived from an MeCP2-Null Mouse Model of Rett Syndrome

(2012) Yasunori Okabe et al.   PLoS One

Acetyl-L-Carnitine Improves Behavior and Dendritic Morphology in a Mouse Model of Rett Syndrome

(2012) Laura R. Schaevitz et al.   PLoS One

Novel MeCP2 Isoform-Specific Antibody Reveals the Endogenous MeCP2E1 Expression in Murine Brain, Primary Neurons and Astrocytes

(2012) Robby M. Zachariah et al.   PLoS One

Fingolimod, a sphingosine-1 phosphate receptor modulator, increases BDNF levels and improves symptoms of a mouse model of Rett syndrome

(2012) R. Deogracias et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coil-to-helix transitions in intrinsically disordered methyl CpG binding protein 2 and its isolated domains

(2012) Kristopher C. Hite et al.   PROTEIN SCIENCE

Linking Epigenetics to Human Disease and Rett Syndrome: The Emerging Novel and Challenging Concepts in MeCP2 Research

(2012) Robby Mathew Zachariah et al.   NEURAL PLASTICITY

The Genetic and Epigenetic Journey of Embryonic Stem Cells into Mature Neural Cells

(2012) Brendan M. Olynik et al.   Frontiers in Genetics

Epigenetic CpG Demethylation of the Promoter and Reactivation of the Expression of Neurog1 by Curcumin in Prostate LNCaP Cells

(2011) Limin Shu et al.   AAPS Journal

Chronic Intermittent Ethanol Exposure and Its Removal Induce a Different miRNA Expression Pattern in Primary Cortical Neuronal Cultures

(2011) Yingqiu Guo et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Mutations in MECP2 exon 1 in classical rett patients disrupt MECP2_e1 transcription, but not transcription of MECP2_e2

(2011) Peter J. Gianakopoulos et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

The Role of MeCP2 in the Brain

(2011) Jacky Guy et al.   Annual Review of Cell and Developmental Biology

Clonal Rett Syndrome cell lines to test compounds for activation of wild-type MeCP2 expression

(2011) Dongbo Yu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Intrathecal 5-azacytidine inhibits global DNA methylation and methyl- CpG-binding protein 2 expression and alleviates neuropathic pain in rats following chronic constriction injury

(2011) Ying Wang et al.   BRAIN RESEARCH

Disrupted microRNA expression caused by Mecp2 loss in a mouse model of Rett syndrome

(2011) Rocio G. Urdinguio et al.   Epigenetics

Transgenic complementation of MeCP2 deficiency: phenotypic rescue of Mecp2-null mice by isoform-specific transgenes

(2011) Bredford Kerr et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Experimental models of Rett syndrome based on Mecp2 dysfunction

(2011) Gaston Calfa et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

MeCP2 Rett mutations affect large scale chromatin organization

(2011) Noopur Agarwal et al.   HUMAN MOLECULAR GENETICS

Reduced AKT/mTOR signaling and protein synthesis dysregulation in a Rett syndrome animal model

(2011) Sara Ricciardi et al.   HUMAN MOLECULAR GENETICS

The Chromatin-binding Protein HMGN1 Regulates the Expression of Methyl CpG-binding Protein 2 (MECP2) and Affects the Behavior of Mice

(2011) Liron Abuhatzira et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Clinical and Electroencephalographic Effects of Folinic Acid Treatment in Rett Syndrome Patients

(2011) Eveline E. O. Hagebeuk et al.   JOURNAL OF CHILD NEUROLOGY

A role for glia in the progression of Rett’s syndrome

(2011) Daniel T. Lioy et al.   NATURE

Rett syndrome mutation MeCP2 T158A disrupts DNA binding, protein stability and ERP responses

(2011) Darren Goffin et al.   NATURE NEUROSCIENCE

Loss of activity-induced phosphorylation of MeCP2 enhances synaptogenesis, LTP and spatial memory

(2011) Hongda Li et al.   NATURE NEUROSCIENCE

MeCP2 is required for global heterochromatic and nucleolar changes during activity-dependent neuronal maturation

(2011) Malaika K. Singleton et al.   NEUROBIOLOGY OF DISEASE

Cocaine increases phosphorylation of MeCP2 in the rat striatum in vivo: A differential role of NMDA receptors

(2011) Li-Min Mao et al.   NEUROCHEMISTRY INTERNATIONAL

Genome-Wide Activity-Dependent MeCP2 Phosphorylation Regulates Nervous System Development and Function

(2011) Sonia Cohen et al.   NEURON

Ex Vivo Treatment with a Novel Synthetic Aminoglycoside NB54 in Primary Fibroblasts from Rett Syndrome Patients Suppresses MECP2 Nonsense Mutations

(2011) Manuela Vecsler et al.   PLoS One

Autism-Associated Gene Expression in Peripheral Leucocytes Commonly Observed between Subjects with Autism and Healthy Women Having Autistic Children

(2011) Yuki Kuwano et al.   PLoS One

Neuronal maturation defect in induced pluripotent stem cells from patients with Rett syndrome

(2011) K.-Y. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adult Neural Function Requires MeCP2

(2011) C. M. McGraw et al.   SCIENCE

Pathogenesis of Lethal Cardiac Arrhythmias in Mecp2 Mutant Mice: Implication for Therapy in Rett Syndrome

(2011) M. D. McCauley et al.   Science Translational Medicine

Epigenetic control of Hox genes during neurogenesis, development, and disease

(2010) Benjamin A. Barber et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

Unique Physical Properties and Interactions of the Domains of Methylated DNA Binding Protein 2

(2010) Rajarshi P. Ghosh et al.   BIOCHEMISTRY

Early Environmental Enrichment Moderates the Behavioral and Synaptic Phenotype of MeCP2 Null Mice

(2010) Giuseppina Lonetti et al.   BIOLOGICAL PSYCHIATRY

Epigenetic Transmission of the Impact of Early Stress Across Generations

(2010) Tamara B. Franklin et al.   BIOLOGICAL PSYCHIATRY

A brain-derived MeCP2 complex supports a role for MeCP2 in RNA processing

(2010) Steven W. Long et al.   BIOSCIENCE REPORTS

Abnormalities of cell packing density and dendritic complexity in the MeCP2 A140V mouse model of Rett syndrome/X-linked mental retardation

(2010) Garilyn M Jentarra et al.   BMC NEUROSCIENCE

Rett syndrome with and without detected MECP2 mutations: An attempt to redefine phenotypes

(2010) Teresa Temudo et al.   BRAIN & DEVELOPMENT

A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells

(2010) Maria C.N. Marchetto et al.   CELL

ATRX Partners with Cohesin and MeCP2 and Contributes to Developmental Silencing of Imprinted Genes in the Brain

(2010) Kristin D. Kernohan et al.   DEVELOPMENTAL CELL

Pons tumour behind a phenotypic Rett syndrome presentation

(2010) R. Vanhala et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Feeding ability in Rett syndrome

(2010) R E. Morton et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Binding of the Rett syndrome protein, MeCP2, to methylated and unmethylated DNA and chromatin

(2010) Jeffrey C. Hansen et al.   IUBMB LIFE

Cross talk between microRNA and epigenetic regulation in adult neurogenesis

(2010) Keith E. Szulwach et al.   JOURNAL OF CELL BIOLOGY

Ischemic Preconditioning Regulates Expression of microRNAs and a Predicted Target, MeCP2, in Mouse Cortex

(2010) Theresa A Lusardi et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Readthrough of nonsense mutations in Rett syndrome: evaluation of novel aminoglycosides and generation of a new mouse model

(2010) Cornelia Brendel et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Exogenous Brain-Derived Neurotrophic Factor Rescues Synaptic Dysfunction in Mecp2-Null Mice

(2010) D. D. Kline et al.   JOURNAL OF NEUROSCIENCE

Rett Syndrome Microglia Damage Dendrites and Synapses by the Elevated Release of Glutamate

(2010) I. Maezawa et al.   JOURNAL OF NEUROSCIENCE

Glatiramer acetate (GA, Copolymer-1) an hypothetical treatment option for Rett syndrome

(2010) B. Ben-Zeev et al.   MEDICAL HYPOTHESES

MeCP2 Binds Cooperatively to Its Substrate and Competes with Histone H1 for Chromatin Binding Sites

(2010) R. P. Ghosh et al.   MOLECULAR AND CELLULAR BIOLOGY

Neuronal MeCP2 Is Expressed at Near Histone-Octamer Levels and Globally Alters the Chromatin State

(2010) Peter J. Skene et al.   MOLECULAR CELL

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

(2010) Hsiao-Tuan Chao et al.   NATURE

MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212

(2010) Heh-In Im et al.   NATURE NEUROSCIENCE

A novel transcriptional regulator of myelin gene expression: implications for neurodevelopmental disorders

(2010) Parvez Vora et al.   NEUROREPORT

Unconventional Transcriptional Response to Environmental Enrichment in a Mouse Model of Rett Syndrome

(2010) Bredford Kerr et al.   PLoS One

Genome-wide analysis reveals methyl-CpG-binding protein 2-dependent regulation of microRNAs in a mouse model of Rett syndrome

(2010) H. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alternative polyadenylation of MeCP2: influence of cis-acting elements and trans-acting factors

(2010) Catherine M. Newnham et al.   RNA Biology

Novel exon 1 mutations in MECP2 implicate isoform MeCP2_e1 in classical Rett syndrome

(2009) Carol J. Saunders et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Mouse models of Rett syndrome: from behavioural phenotyping to preclinical evaluation of new therapeutic approaches

(2009) Laura Ricceri et al.   BEHAVIOURAL PHARMACOLOGY

MeCP2 post-translational regulation through PEST domains: two novel hypotheses

(2009) Anita A. Thambirajah et al.   BIOESSAYS

Neuronal differentiation of neural precursor cells is promoted by the methyl-CpG-binding protein MeCP2

(2009) Keita Tsujimura et al.   EXPERIMENTAL NEUROLOGY

MeCP2 functions largely cell-autonomously, but also non-cell-autonomously, in neuronal maturation and dendritic arborization of cortical pyramidal neurons

(2009) Noriyuki Kishi et al.   EXPERIMENTAL NEUROLOGY

miR-212 is downregulated and suppresses methyl-CpG-binding protein MeCP2 in human gastric cancer

(2009) Rie Wada et al.   INTERNATIONAL JOURNAL OF CANCER

Chromosome 21-derived MicroRNAs Provide an Etiological Basis for Aberrant Protein Expression in Human Down Syndrome Brains

(2009) Donald E. Kuhn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epigenetic control

(2009) Geneviève P. Delcuve et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Widespread changes in dendritic and axonal morphology inMecp2-mutant mouse models of rett syndrome: Evidence for disruption of neuronal networks

(2009) Pavel V. Belichenko et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Phenotypic variability in Rett syndrome associated with FOXG1 mutations in females

(2009) C. Philippe et al.   JOURNAL OF MEDICAL GENETICS

MeCP2 Function in the Basolateral Amygdala in Rett Syndrome

(2009) S. H. Wu et al.   JOURNAL OF NEUROSCIENCE

Rett Syndrome Astrocytes Are Abnormal and Spread MeCP2 Deficiency through Gap Junctions

(2009) I. Maezawa et al.   JOURNAL OF NEUROSCIENCE

Histone Deacetylases 1 and 2 Form a Developmental Switch That Controls Excitatory Synapse Maturation and Function

(2009) M. W. Akhtar et al.   JOURNAL OF NEUROSCIENCE

MeCP2-Mediated Transcription Repression in the Basolateral Amygdala May Underlie Heightened Anxiety in a Mouse Model of Rett Syndrome

(2009) M. Adachi et al.   JOURNAL OF NEUROSCIENCE

Stereotypical hand movements in 144 subjects with Rett syndrome from the population-based Australian database

(2009) Philippa Carter et al.   MOVEMENT DISORDERS

Non–cell autonomous influence of MeCP2-deficient glia on neuronal dendritic morphology

(2009) Nurit Ballas et al.   NATURE NEUROSCIENCE

Evidence for both neuronal cell autonomous and nonautonomous effects of methyl-CpG-binding protein 2 in the cerebral cortex of female mice with Mecp2 mutation

(2009) Nadia P. Belichenko et al.   NEUROBIOLOGY OF DISEASE

Dendritic spine pathologies in hippocampal pyramidal neurons from Rett syndrome brain and after expression of Rett-associated MECP2 mutations

(2009) Christopher A. Chapleau et al.   NEUROBIOLOGY OF DISEASE

Bdnf overexpression in hippocampal neurons prevents dendritic atrophy caused by Rett-associated MECP2 mutations

(2009) Jennifer L. Larimore et al.   NEUROBIOLOGY OF DISEASE

Suppression of Nonsense Mutations in Rett Syndrome by Aminoglycoside Antibiotics

(2009) Cornelia Brendel et al.   PEDIATRIC RESEARCH

MECP2 Isoform-Specific Vectors with Regulated Expression for Rett Syndrome Gene Therapy

(2009) Mojgan Rastegar et al.   PLoS One

Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function

(2009) J. Tao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice

(2009) Daniela Tropea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Breathing disorders in Rett syndrome: Progressive neurochemical dysfunction in the respiratory network after birth

(2009) David M. Katz et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

MECP2promoter methylation and X chromosome inactivation in autism

(2008) Raman P. Nagarajan et al.   Autism Research

Silencing of MBD1 and MeCP2 in prostate-cancer-derived PC3 cells produces differential gene expression profiles and cellular phenotypes

(2008) Ahmed Yaqinuddin et al.   BIOSCIENCE REPORTS

Effects of postnatal dietary choline supplementation on motor regional brain volume and growth factor expression in a mouse model of Rett syndrome

(2008) Nupur Nag et al.   BRAIN RESEARCH

Environmental enrichment ameliorates a motor coordination deficit in a mouse model of Rett syndromeMecp2gene dosage effects and BDNF expression

(2008) Mari Kondo et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Clinically relevant concentrations of valproic acid modulate melatonin MT1 receptor, HDAC and MeCP2 mRNA expression in C6 glioma cells

(2008) Bora Kim et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Methyl-CpG-binding protein 2 polymorphisms and vulnerability to autism

(2008) C. S. Loat et al.   GENES BRAIN AND BEHAVIOR

Targeted delivery of an Mecp2 transgene to forebrain neurons improves the behavior of female Mecp2-deficient mice

(2008) D. G.M. Jugloff et al.   HUMAN MOLECULAR GENETICS

MeCP2-dependent repression of an imprinted miR-184 released by depolarization

(2008) Tasuku Nomura et al.   HUMAN MOLECULAR GENETICS

RNAi-induced down-regulation of Mecp2 expression in the rat brain

(2008) Jing Jin et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Analysis of protein domains and Rett syndrome mutations indicate that multiple regions influence chromatin-binding dynamics of the chromatin-associated protein MECP2 in vivo

(2008) A. Kumar et al.   JOURNAL OF CELL SCIENCE

MeCP2 Binding to DNA Depends upon Hydration at Methyl-CpG

(2008) Kok Lian Ho et al.   MOLECULAR CELL

The first missense mutation causing Rett syndrome specifically affecting the MeCP2_e1 isoform

(2008) Yann Fichou et al.   NEUROGENETICS

Deletion of Mecp2 in Sim1-Expressing Neurons Reveals a Critical Role for MeCP2 in Feeding Behavior, Aggression, and the Response to Stress

(2008) Sharyl L. Fyffe et al.   NEURON

MECP2 genomic structure and function: insights from ENCODE

(2008) J. Singh et al.   NUCLEIC ACIDS RESEARCH

Autism: Definition, Neurobiology, Screening, Diagnosis

(2008) Isabelle Rapin et al.   PEDIATRIC CLINICS OF NORTH AMERICA

A quantitative atlas of mitotic phosphorylation

(2008) N. Dephoure et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Breathing dysfunction in Rett syndrome: Understanding epigenetic regulation of the respiratory network

(2008) Michael Ogier et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription

(2008) M. Chahrour et al.   SCIENCE

Genetic Modifiers of MeCP2 Function in Drosophila

(2008) Holly N. Cukier et al.   PLoS Genetics

Oral treatment with desipramine improves breathing and life span in Rett syndrome mouse model

(2007) Sébastien Zanella et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY