标题
Scaffold-Mediated Gene Delivery for Osteochondral Repair
作者
关键词
-
出版物
Pharmaceutics
Volume 12, Issue 10, Pages 930
出版商
MDPI AG
发表日期
2020-09-30
DOI
10.3390/pharmaceutics12100930
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Non-Viral in Vitro Gene Delivery: It is Now Time to Set the Bar!
- (2020) Nina Bono et al. Pharmaceutics
- Niosome-Based Approach for In Situ Gene Delivery to Retina and Brain Cortex as Immune-Privileged Tissues
- (2020) Nuseibah AL Qtaish et al. Pharmaceutics
- Enhanced Chondrogenic Differentiation Activities in Human Bone Marrow Aspirates via sox9 Overexpression Mediated by pNaSS-Grafted PCL Film-Guided rAAV Gene Transfer
- (2020) Jagadeesh K. Venkatesan et al. Pharmaceutics
- mRNA-activated matrices encoding transcription factors as primers of cell differentiation in tissue engineering
- (2020) Adriana M. Ledo et al. BIOMATERIALS
- Small-Diameter Subchondral Drilling Improves DNA and Proteoglycan Content of the Cartilaginous Repair Tissue in a Large Animal Model of a Full-Thickness Chondral Defect
- (2020) Patrick Orth et al. Journal of Clinical Medicine
- Hydrogel-Based Localized Nonviral Gene Delivery in Regenerative Medicine Approaches—An Overview
- (2020) Natalia Carballo-Pedrares et al. Pharmaceutics
- 3D printing of fibre-reinforced cartilaginous templates for the regeneration of osteochondral defects
- (2020) Susan Critchley et al. Acta Biomaterialia
- Osteochondral Autograft Transplantation Technique Augmented by an Ultrapurified Alginate Gel Enhances Osteochondral Repair in a Rabbit Model
- (2019) Ryosuke Hishimura et al. AMERICAN JOURNAL OF SPORTS MEDICINE
- Pore-forming bioinks to enable spatio-temporally defined gene delivery in bioprinted tissues
- (2019) T. Gonzalez-Fernandez et al. JOURNAL OF CONTROLLED RELEASE
- Scaffold‐Based Delivery of Nucleic Acid Therapeutics for Enhanced Bone and Cartilage Repair
- (2019) Domhnall C Kelly et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Polymeric Nanoparticles in Gene Therapy: New Avenues of Design and Optimization for Delivery Applications
- (2019) Raj Rai et al. Polymers
- Cationic micelle: A promising nanocarrier for gene delivery with high transfection efficiency
- (2019) Haili Wang et al. JOURNAL OF GENE MEDICINE
- Surgical and tissue engineering strategies for articular cartilage and meniscus repair
- (2019) Heenam Kwon et al. Nature Reviews Rheumatology
- Thermosensitive Hydrogel Based on PEO–PPO–PEO Poloxamers for a Controlled In Situ Release of Recombinant Adeno‐Associated Viral Vectors for Effective Gene Therapy of Cartilage Defects
- (2019) Henning Madry et al. ADVANCED MATERIALS
- Internal Fixation of Osteochondritis Dissecans of the Knee Leads to Good Long-Term Outcomes and High Degree of Healing without Differences between Fixation Devices
- (2019) Simone Perelli et al. Journal of Clinical Medicine
- Regulation of decellularized tissue remodeling via scaffold-mediated lentiviral delivery in anatomically-shaped osteochondral constructs
- (2018) Christopher R. Rowland et al. BIOMATERIALS
- Chondrogenic Differentiation Processes in Human Bone-Marrow Aspirates Seeded in Three-Dimensional-Woven Poly(ɛ-Caprolactone) Scaffolds Enhanced by Recombinant Adeno-Associated Virus–Mediated SOX9 Gene Transfer
- (2018) Jagadeesh K. Venkatesan et al. HUMAN GENE THERAPY
- Electrospun Fibrous Scaffolds for Tissue Engineering: Viewpoints on Architecture and Fabrication
- (2018) Indong Jun et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Delivery of the improved BMP-2-Advanced plasmid DNA within a gene-activated scaffold accelerates mesenchymal stem cell osteogenesis and critical size defect repair
- (2018) Rosanne M. Raftery et al. JOURNAL OF CONTROLLED RELEASE
- Messenger RNA Delivery for Tissue Engineering and Regenerative Medicine Applications
- (2018) Siddharth Patel et al. TISSUE ENGINEERING PART A
- Efficacy of Octacalcium Phosphate Collagen Composite for Titanium Dental Implants in Dogs
- (2018) Tadashi Kawai et al. Materials
- Animal models used for testing hydrogels in cartilage regeneration
- (2018) Chuntie Zhu et al. Current Stem Cell Research & Therapy
- 3D Printing and Electrospinning of Composite Hydrogels for Cartilage and Bone Tissue Engineering
- (2018) Arianna De Mori et al. Polymers
- Current state of fabrication technologies and materials for bone tissue engineering
- (2018) Abiy Wubneh et al. Acta Biomaterialia
- Improved Chondrogenic Differentiation of rAAV SOX9-Modified Human MSCs Seeded in Fibrin-Polyurethane Scaffolds in a Hydrodynamic Environment
- (2018) Jagadeesh Venkatesan et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Biomaterial-guided delivery of gene vectors for targeted articular cartilage repair
- (2018) Magali Cucchiarini et al. Nature Reviews Rheumatology
- rAAV-mediated overexpression of TGF-β via vector delivery in polymeric micelles stimulates the biological and reparative activities of human articular chondrocytes in vitro and in a human osteochondral defect model
- (2017) Ana Rey-Rico et al. International Journal of Nanomedicine
- Tailoring biomaterial scaffolds for osteochondral repair
- (2017) Sandra Camarero-Espinosa et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Regeneration of bone using nanoplex delivery of FGF-2 and BMP-2 genes in diaphyseal long bone radial defects in a diabetic rabbit model
- (2017) Behnoush Khorsand et al. JOURNAL OF CONTROLLED RELEASE
- Modified mRNA for BMP-2 in Combination with Biomaterials Serves as a Transcript-Activated Matrix for Effectively Inducing Osteogenic Pathways in Stem Cells
- (2017) Elizabeth R. Balmayor et al. STEM CELLS AND DEVELOPMENT
- Non-viral gene activated matrices for mesenchymal stem cells based tissue engineering of bone and cartilage
- (2016) Sophie Raisin et al. BIOMATERIALS
- Effect of sustained PDGF nonviral gene delivery on repair of tooth-supporting bone defects
- (2016) A B Plonka et al. GENE THERAPY
- Chitosan based biocomposite scaffolds for bone tissue engineering
- (2016) S. Saravanan et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Cationized gelatin hydrogels mixed with plasmid DNA induce stronger and more sustained gene expression than atelocollagen at calvarial bone defectsin vivo
- (2016) K. Komatsu et al. JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
- Accelerated bony defect healing based on chitosan thermosensitive hydrogel scaffolds embedded with chitosan nanoparticles for the delivery of BMP2 plasmid DNA
- (2016) Hui Li et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Scaffold-mediated BMP-2 minicircle DNA delivery accelerated bone repair in a mouse critical-size calvarial defect model
- (2016) Michael Keeney et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Progress in the development of lipopolyplexes as efficient non-viral gene delivery systems
- (2016) Mehdi Rezaee et al. JOURNAL OF CONTROLLED RELEASE
- Characterization and cytocompatibility of thermosensitive hydrogel embedded with chitosan nanoparticles for delivery of bone morphogenetic protein-2 plasmid DNA
- (2016) Dan-Dan Li et al. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
- Retroviral vectors and transposons for stable gene therapy: advances, current challenges and perspectives
- (2016) José Eduardo Vargas et al. Journal of Translational Medicine
- Early osteoarthritis of the knee
- (2016) Henning Madry et al. KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
- Anatomically shaped tissue-engineered cartilage with tunable and inducible anticytokine delivery for biological joint resurfacing
- (2016) Franklin T. Moutos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gene Delivery of TGF-β3 and BMP2 in an MSC-Laden Alginate Hydrogel for Articular Cartilage and Endochondral Bone Tissue Engineering
- (2016) Tomas Gonzalez-Fernandez et al. TISSUE ENGINEERING PART A
- PEO–PPO–PEO micelles as effective rAAV-mediated gene delivery systems to target human mesenchymal stem cells without altering their differentiation potency
- (2015) Ana Rey-Rico et al. Acta Biomaterialia
- Type II collagen and glycosaminoglycan expression induction in primary human chondrocyte by TGF-β1
- (2015) Hyun Joo Yoon et al. BMC MUSCULOSKELETAL DISORDERS
- Carboxymethylcellulose (CMC) formed nanogels with branched poly(ethyleneimine) (bPEI) for inhibition of cytotoxicity in human MSCs as a gene delivery vehicles
- (2015) Han Na Yang et al. CARBOHYDRATE POLYMERS
- A Pilot Study Evaluating Combinatorial and Simultaneous Delivery of Polyethylenimine-Plasmid DNA Complexes Encoding for VEGF and PDGF for Bone Regeneration in Calvarial Bone Defects
- (2015) Sheetal D'Mello et al. CURRENT PHARMACEUTICAL BIOTECHNOLOGY
- rAAV-mediated overexpression of sox9, TGF-β and IGF-I in minipig bone marrow aspirates to enhance the chondrogenic processes for cartilage repair
- (2015) J Frisch et al. GENE THERAPY
- The grafting of a thin layer of poly(sodium styrene sulfonate) onto poly(ε-caprolactone) surface can enhance fibroblast behavior
- (2015) Géraldine Rohman et al. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
- Tendon and ligament regeneration and repair: Clinical relevance and developmental paradigm
- (2015) Guang Yang et al. BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS
- Human Articular Cartilage Progenitor Cells Are Responsive to Mechanical Stimulation and Adenoviral-Mediated Overexpression of Bone-Morphogenetic Protein 2
- (2015) Alexander J. Neumann et al. PLoS One
- Osteochondral tissue regeneration through polymeric delivery of DNA encoding for the SOX trio and RUNX2
- (2014) Clark J. Needham et al. Acta Biomaterialia
- Tissue-engineered cartilage with inducible and tunable immunomodulatory properties
- (2014) Katherine A. Glass et al. BIOMATERIALS
- Impact of DNA Vector Topology on Non-Viral Gene Therapeutic Safety and Efficacy
- (2014) Chi Sum et al. CURRENT GENE THERAPY
- Towards the development of polycaprolactone based amphiphilic block copolymers: molecular design, self-assembly and biomedical applications
- (2014) Zibiao Li et al. Materials Science & Engineering C-Materials for Biological Applications
- Poly(lactide-co-glycolide)/Fibrin Gel Construct as a 3D Model to Evaluate Gene Therapy of Cartilage in Vivo
- (2014) Bo Li et al. MOLECULAR PHARMACEUTICS
- Demineralized Bone Matrix Combined Bone Marrow Mesenchymal Stem Cells, Bone Morphogenetic Protein-2 and Transforming Growth Factor-β3 Gene Promoted Pig Cartilage Defect Repair
- (2014) Xin Wang et al. PLoS One
- Scaffold-mediated lentiviral transduction for functional tissue engineering of cartilage
- (2014) Jonathan M. Brunger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bioinspired Scaffolds for Osteochondral Regeneration
- (2014) Silvia Lopa et al. TISSUE ENGINEERING PART A
- Combinatorial Gene Therapy Accelerates Bone Regeneration: Non-Viral Dual Delivery of VEGF and BMP2 in a Collagen-Nanohydroxyapatite Scaffold
- (2014) Caroline M. Curtin et al. Advanced Healthcare Materials
- DNA Ministrings: Highly Safe and Effective Gene Delivery Vectors
- (2014) Nafiseh Nafissi et al. Molecular Therapy-Nucleic Acids
- The enhancement of bone regeneration by gene activated matrix encoding for platelet derived growth factor
- (2013) Satheesh Elangovan et al. BIOMATERIALS
- Fabrication of poly(lactide-co-glycolide) scaffold filled with fibrin gel, mesenchymal stem cells, and poly(ethylene oxide)-b-poly(L-lysine)/TGF-β1 plasmid DNA complexes for cartilage restorationin vivo
- (2013) Bo Li et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Endogenous versus exogenous growth factor regulation of articular chondrocytes
- (2013) Shuiliang Shi et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Regenerating Cartilages by Engineered ASCs: Prolonged TGF-β3/BMP-6 Expression Improved Articular Cartilage Formation and Restored Zonal Structure
- (2013) Chia-Hsin Lu et al. MOLECULAR THERAPY
- Gene delivery techniques for adult stem cell-based regenerative therapy
- (2013) Seog-Jin Seo et al. Nanomedicine
- Mesenchymal stem cells in joint disease and repair
- (2013) Frank Barry et al. Nature Reviews Rheumatology
- Porous Chitosan Scaffolds with Embedded Hyaluronic Acid/Chitosan/Plasmid-DNA Nanoparticles Encoding TGF-β1 Induce DNA Controlled Release, Transfected Chondrocytes, and Promoted Cell Proliferation
- (2013) Huading Lu et al. PLoS One
- The potential of gene transfer for the treatment of osteoarthritis
- (2013) Magali Cucchiarini et al. Regenerative Medicine
- Chondrogenesis of Human Bone Marrow-Derived Mesenchymal Stem Cells Is Modulated by Complex Mechanical Stimulation and Adenoviral-Mediated Overexpression of Bone Morphogenetic Protein 2
- (2013) Alexander J. Neumann et al. TISSUE ENGINEERING PART A
- Analyses of chondrogenic induction of adipose mesenchymal stem cells by combined co-stimulation mediated by adenoviral gene transfer
- (2013) Idalia Garza-Veloz et al. ARTHRITIS RESEARCH & THERAPY
- Porous bioprinted constructs in BMP-2 non-viral gene therapy for bone tissue engineering
- (2013) Loek D. Loozen et al. Journal of Materials Chemistry B
- TGF-β1 gene-engineered mesenchymal stem cells induce rat cartilage regeneration using nonviral gene vector
- (2012) Cai-Xia He et al. BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY
- Critical size defect regeneration using PEG-mediated BMP-2 gene delivery and the use of cell occlusive barrier membranes - the osteopromotive principle revisited
- (2012) Falk Wehrhan et al. CLINICAL ORAL IMPLANTS RESEARCH
- TGF-β and BMP Signaling in Osteoblast Differentiation and Bone Formation
- (2012) Guiqian Chen et al. International Journal of Biological Sciences
- Osteochondral tissue engineering: scaffolds, stem cells and applications
- (2012) Patcharakamon Nooeaid et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Gene delivery of bone morphogenetic protein-2 plasmid DNA promotes bone formation in a large animal model
- (2012) Fiona Wegman et al. Journal of Tissue Engineering and Regenerative Medicine
- Reconstruct large osteochondral defects of the knee with hIGF-1 gene enhanced Mosaicplasty
- (2012) Ping Leng et al. KNEE
- The promotion of cartilage defect repair using adenovirus mediated Sox9 gene transfer of rabbit bone marrow mesenchymal stem cells
- (2011) Lei Cao et al. BIOMATERIALS
- Simultaneous regeneration of articular cartilage and subchondral bone in vivo using MSCs induced by a spatially controlled gene delivery system in bilayered integrated scaffolds
- (2011) Jiangning Chen et al. BIOMATERIALS
- SOX trio-co-transduced adipose stem cells in fibrin gel to enhance cartilage repair and delay the progression of osteoarthritis in the rat
- (2011) Jong-Min Lee et al. BIOMATERIALS
- The Role of Growth Factors in Cartilage Repair
- (2011) Lisa A. Fortier et al. CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
- The Sleeping Beauty transposon system: a non-viral vector for gene therapy
- (2011) E. L. Aronovich et al. HUMAN MOLECULAR GENETICS
- Occurrence, biochemical profile of vascular endothelial growth factor (VEGF) isoforms and their functions in endochondral ossification
- (2011) A.S. Patil et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The development of non-viral gene-activated matrices for bone regeneration using polyethyleneimine (PEI) and collagen-based scaffolds
- (2011) Erica G. Tierney et al. JOURNAL OF CONTROLLED RELEASE
- Poly-є-caprolactone based formulations for drug delivery and tissue engineering: A review
- (2011) Tapan K. Dash et al. JOURNAL OF CONTROLLED RELEASE
- Regulation of articular chondrocyte aggrecan and collagen gene expression by multiple growth factor gene transfer
- (2011) Shuiliang Shi et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- PDGF in bone formation and regeneration: New insights into a novel mechanism involving MSCs
- (2011) Arnold I. Caplan et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Critical-size defect induces unicompartmental osteoarthritis in a stable ovine knee
- (2011) Martina Schinhan et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Direct delayed human adenoviral BMP-2 or BMP-6 gene therapy for bone and cartilage regeneration in a pony osteochondral model
- (2011) M.I. Menendez et al. OSTEOARTHRITIS AND CARTILAGE
- IGF-1 and BMP-2 Induces Differentiation of Adipose-Derived Mesenchymal Stem Cells into Chondrocytes-Like Cells
- (2010) Chunhou An et al. ANNALS OF BIOMEDICAL ENGINEERING
- In vivo restoration of full-thickness cartilage defects by poly(lactide-co-glycolide) sponges filled with fibrin gel, bone marrow mesenchymal stem cells and DNA complexes
- (2010) Wei Wang et al. BIOMATERIALS
- Localized Delivery of Antisense Oligonucleotides by Cationic Hydrogel Suppresses TNF-α Expression and Endotoxin-Induced Osteolysis
- (2010) Lei Dong et al. PHARMACEUTICAL RESEARCH
- Blocking vascular endothelial growth factor with soluble Flt-1 improves the chondrogenic potential of mouse skeletal muscle-derived stem cells
- (2009) Seiji Kubo et al. ARTHRITIS AND RHEUMATISM
- Adenoviral transduction of hTGF-β1 enhances the chondrogenesis of bone marrow derived stromal cells
- (2009) Wanyao Xia et al. BIOTECHNOLOGY LETTERS
- Calcium phosphate-DNA nanoparticle gene delivery from alginate hydrogels inducesin vivoosteogenesis
- (2009) Melissa D. Krebs et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- The Osteochondral Junction and Its Repair via Bi-Phasic Tissue Engineering Scaffolds
- (2009) Michael Keeney et al. TISSUE ENGINEERING PART B-REVIEWS
- Characterized Chondrocyte Implantation Results in Better Structural Repair When Treating Symptomatic Cartilage Defects of the Knee in a Randomized Controlled Trial versus Microfracture
- (2008) Daniel B. F. Saris et al. AMERICAN JOURNAL OF SPORTS MEDICINE
- The synergistic effects of microfracture, perforated decalcified cortical bone matrix and adenovirus-bone morphogenetic protein-4 in cartilage defect repair
- (2008) Xin Zhang et al. BIOMATERIALS
- The repair of osteochondral defects using baculovirus-mediated gene transfer with de-differentiated chondrocytes in bioreactor culture
- (2008) Huang-Chi Chen et al. BIOMATERIALS
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