Anatomically shaped tissue-engineered cartilage with tunable and inducible anticytokine delivery for biological joint resurfacing

Quality of life after bilateral total knee arthroplasty determined by a 3-year longitudinal evaluation using the Japanese knee osteoarthritis measure

(2015) Takehiko Sugita et al.   JOURNAL OF ORTHOPAEDIC SCIENCE

Matrix Production in Large Engineered Cartilage Constructs Is Enhanced by Nutrient Channels and Excess Media Supply

(2015) Robert J. Nims et al.   TISSUE ENGINEERING PART C-METHODS

Tissue-engineered cartilage with inducible and tunable immunomodulatory properties

(2014) Katherine A. Glass et al.   BIOMATERIALS

Large, stratified, and mechanically functional human cartilage grown in vitro by mesenchymal condensation

(2014) S. Bhumiratana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Scaffold-mediated lentiviral transduction for functional tissue engineering of cartilage

(2014) Jonathan M. Brunger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Implantation of Scaffold-Free Engineered Cartilage Constructs in a Rabbit Model for Chondral Resurfacing

(2013) Jillian M. Brenner et al.   ARTIFICIAL ORGANS

Synovial fluid concentrations and relative potency of interleukin-1 alpha and beta in cartilage and meniscus degradation

(2013) Amy L. McNulty et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Arthritis gene therapy and its tortuous path into the clinic

(2013) Christopher H. Evans et al.   Translational Research

Interleukin-1 beta and tumor necrosis factor alpha inhibit migration activity of chondrogenic progenitor cells from non-fibrillated osteoarthritic cartilage

(2013) Helga Joos et al.   ARTHRITIS RESEARCH & THERAPY

The inhibition by interleukin 1 of MSC chondrogenesis and the development of biomechanical properties in biomimetic 3D woven PCL scaffolds

(2012) Paul H. Ousema et al.   BIOMATERIALS

scAAV-mediated gene transfer of interleukin-1-receptor antagonist to synovium and articular cartilage in large mammalian joints

(2012) R S Watson et al.   GENE THERAPY

Total Hip Arthroplasty in the Very Young Patient

(2012) Gregory G. Polkowski et al.   JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS

Enhanced Adenovirus Transduction of hMSCs Using 3D Hydrogel Cell Carriers

(2012) Alexander J. Neumann et al.   MOLECULAR BIOTECHNOLOGY

Effects of intraarticular IL1-Ra for acute anterior cruciate ligament knee injury: a randomized controlled pilot trial (NCT00332254)

(2012) V.B. Kraus et al.   OSTEOARTHRITIS AND CARTILAGE

IL-1ra delivered from poly(lactic-co-glycolic acid) microspheres attenuates IL-1beta mediated degradation of nucleus pulposus in vitro

(2012) Deborah J Gorth et al.   ARTHRITIS RESEARCH & THERAPY

Chondrogenic differentiation of human subchondral progenitor cells is affected by synovial fluid from donors with osteoarthritis or rheumatoid arthritis

(2012) Jan Krüger et al.   Journal of Orthopaedic Surgery and Research

Response of Human Engineered Cartilage Based on Articular or Nasal Chondrocytes to Interleukin-1β and Low Oxygen

(2011) Celeste Scotti et al.   TISSUE ENGINEERING PART A

Catabolic Factors and Osteoarthritis-Conditioned Medium Inhibit Chondrogenesis of Human Mesenchymal Stem Cells

(2011) Genoveva T.H. Heldens et al.   TISSUE ENGINEERING PART A

In vitro generation of mechanically functional cartilage grafts based on adult human stem cells and 3D-woven poly(ɛ-caprolactone) scaffolds

(2010) Piia K. Valonen et al.   BIOMATERIALS

Regeneration of the articular surface of the rabbit synovial joint by cell homing: a proof of concept study

(2010) Chang H Lee et al.   LANCET

Multifunctional Hybrid Three-dimensionally Woven Scaffolds for Cartilage Tissue Engineering

(2010) Franklin T. Moutos et al.   MACROMOLECULAR BIOSCIENCE

Isolation of adipose-derived stem cells and their induction to a chondrogenic phenotype

(2010) Bradley T Estes et al.   Nature Protocols

Role of proinflammatory cytokines in the pathophysiology of osteoarthritis

(2010) Mohit Kapoor et al.   Nature Reviews Rheumatology

Comparative Review of Growth Factors for Induction of Three-Dimensional In Vitro Chondrogenesis in Human Mesenchymal Stem Cells Isolated from Bone Marrow and Adipose Tissue

(2010) Jennifer L. Puetzer et al.   TISSUE ENGINEERING PART B-REVIEWS

Intraarticular injection of anakinra in osteoarthritis of the knee: A multicenter, randomized, double-blind, placebo-controlled study

(2009) X. Chevalier et al.   ARTHRITIS AND RHEUMATISM

Interleukin-1β and tumor necrosis factor α inhibit chondrogenesis by human mesenchymal stem cells through NF-κB-dependent pathways

(2009) N. Wehling et al.   ARTHRITIS AND RHEUMATISM

Rapid prototyping of anatomically shaped, tissue-engineered implants for restoring congruent articulating surfaces in small joints

(2009) T. B. F. Woodfield et al.   CELL PROLIFERATION

A matrix reservoir for improved control of non-viral gene delivery

(2009) Carolyn Holladay et al.   JOURNAL OF CONTROLLED RELEASE

Functional Properties of Cell-Seeded Three-Dimensionally Woven Poly(ε-Caprolactone) Scaffolds for Cartilage Tissue Engineering

(2009) Franklin T. Moutos et al.   TISSUE ENGINEERING PART A

Transcriptomic Analysis Identifies Foxo3A as a Novel Transcription Factor Regulating Mesenchymal Stem Cell Chrondrogenic Differentiation

(2009) Farida Djouad et al.   Cloning Stem Cells

Freeze-dried Tendon Allografts as Tissue-engineering Scaffolds for Gdf5 Gene Delivery

(2008) Patrick Basile et al.   MOLECULAR THERAPY

Engineering graded tissue interfaces

(2008) J. E. Phillips et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overview of Existing Cartilage Repair Technology

(2008) Allison G. McNickle et al.   SPORTS MEDICINE AND ARTHROSCOPY REVIEW

A novel injectable scaffold for cartilage tissue engineering using adipose-derived adult stem cells

(2007) Yiyong Wei et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Inhibition of integrative repair of the meniscus following acute exposure to interleukin-1 in vitro

(2007) Rebecca E. Wilusz et al.   JOURNAL OF ORTHOPAEDIC RESEARCH