Improved Chondrogenic Differentiation of rAAV SOX9-Modified Human MSCs Seeded in Fibrin-Polyurethane Scaffolds in a Hydrodynamic Environment

A Novel Biodegradable Polyurethane Matrix for Auricular Cartilage Repair

(2016) Kartik Iyer et al.   Journal of Burn Care & Research

The Evidence for Surgical Repair of Articular Cartilage in the Knee

(2016) Marc R. Safran et al.   JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS

Effective and durable genetic modification of human mesenchymal stem cells via controlled release of rAAV vectors from self-assembling peptide hydrogels with a maintained differentiation potency

(2015) Ana Rey-Rico et al.   Acta Biomaterialia

An educational review of cartilage repair: precepts & practice – myths & misconceptions – progress & prospects

(2015) E.B. Hunziker et al.   OSTEOARTHRITIS AND CARTILAGE

Cartilage Repair and Subchondral Bone Remodeling in Response to Focal Lesions in a Mini-Pig Model: Implications for Tissue Engineering

(2015) Matthew B. Fisher et al.   TISSUE ENGINEERING PART A

Current Progress in Stem Cell-Based Gene Therapy for Articular Cartilage Repair

(2015) Janina Frisch et al.   Current Stem Cell Research & Therapy

Determination of the Chondrogenic Differentiation Processes in Human Bone Marrow-Derived Mesenchymal Stem Cells Genetically Modified to Overexpress Transforming Growth Factor-β via Recombinant Adeno-Associated Viral Vectors

(2014) Janina Frisch et al.   HUMAN GENE THERAPY

Influence of insulin-like growth factor I overexpression via recombinant adeno-associated vector gene transfer upon the biological activities and differentiation potential of human bone marrow-derived mesenchymal stem cells

(2014) Janina Frisch et al.   Stem Cell Research & Therapy

rAAV-mediated overexpression of TGF-β stably restructures human osteoarthritic articular cartilage in situ

(2013) Jagadeesh K Venkatesan et al.   Journal of Translational Medicine

Chondrogenesis of Human Bone Marrow-Derived Mesenchymal Stem Cells Is Modulated by Complex Mechanical Stimulation and Adenoviral-Mediated Overexpression of Bone Morphogenetic Protein 2

(2013) Alexander J. Neumann et al.   TISSUE ENGINEERING PART A

Direct rAAV SOX9 administration for durable articular cartilage repair with delayed terminal differentiation and hypertrophy in vivo

(2012) Magali Cucchiarini et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

SOX9 gene transfer via safe, stable, replication-defective recombinant adeno-associated virus vectors as a novel, powerful tool to enhance the chondrogenic potential of human mesenchymal stem cells

(2012) Jagadeesh K Venkatesan et al.   Stem Cell Research & Therapy

Zinc-finger protein 145, acting as an upstream regulator of SOX9, improves the differentiation potential of human mesenchymal stem cells for cartilage regeneration and repair

(2011) Tong Ming Liu et al.   ARTHRITIS AND RHEUMATISM

The promotion of cartilage defect repair using adenovirus mediated Sox9 gene transfer of rabbit bone marrow mesenchymal stem cells

(2011) Lei Cao et al.   BIOMATERIALS

Mesenchymal stem cell therapy for knee osteoarthritis. Preliminary report of four patients

(2011) Fereydoun DAVATCHI et al.   International Journal of Rheumatic Diseases

Metabolic Activities and Chondrogenic Differentiation of Human Mesenchymal Stem Cells Following Recombinant Adeno-Associated Virus–Mediated Gene Transfer and Overexpression of Fibroblast Growth Factor 2

(2011) Magali Cucchiarini et al.   TISSUE ENGINEERING PART A

SOX9 Governs Differentiation Stage-Specific Gene Expression in Growth Plate Chondrocytes via Direct Concomitant Transactivation and Repression

(2011) Victor Y. L. Leung et al.   PLoS Genetics

Safety of autologous bone marrow-derived mesenchymal stem cell transplantation for cartilage repair in 41 patients with 45 joints followed for up to 11 years and 5 months

(2010) Shigeyuki Wakitani et al.   Journal of Tissue Engineering and Regenerative Medicine

Improving Chondrogenesis: Potential and Limitations of SOX9 Gene Transfer and Mechanical Stimulation for Cartilage Tissue Engineering

(2010) Laszlo Kupcsik et al.   TISSUE ENGINEERING PART A

Chondrogenesis of Human Bone Marrow Mesenchymal Stem Cells in Fibrin–Polyurethane Composites

(2008) Zhen Li et al.   TISSUE ENGINEERING PART A

Genetic manipulation of human mesenchymal progenitors to promote chondrogenesis using “bead-in-bead” polysaccharide capsules

(2007) Jodie C. Babister et al.   BIOMATERIALS

Evaluation of adult equine bone marrow- and adipose-derived progenitor cell chondrogenesis in hydrogel cultures

(2007) John D. Kisiday et al.   JOURNAL OF ORTHOPAEDIC RESEARCH