DNA Methylation-Dependent Dysregulation of GABAergic Interneuron Functionality in Neuropsychiatric Diseases

DNA Methylation-Mediated Modulation of Endocytosis as Potential Mechanism for Synaptic Function Regulation in Murine Inhibitory Cortical Interneurons

(2020) Daniel Pensold et al.   CEREBRAL CORTEX

Neuronal Lhx1 expression is regulated by DNMT1-dependent modulation of histone marks

(2020) Judit Symmank et al.   Epigenetics

The importance of long non-coding RNAs in neuropsychiatric disorders

(2019) Ebrahim Hosseini et al.   MOLECULAR ASPECTS OF MEDICINE

The Transcription Factor LHX1 Regulates the Survival and Directed Migration of POA-derived Cortical Interneurons

(2018) Judit Symmank et al.   CEREBRAL CORTEX

DNMT1 modulates interneuron morphology by regulating Pak6 expression through crosstalk with histone modifications

(2018) Judit Symmank et al.   Epigenetics

The contribution of environmental exposure to the etiology of autism spectrum disorder

(2018) Sven Bölte et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

ASD and schizophrenia show distinct developmental profiles in common genetic overlap with population-based social communication difficulties

(2017) B St Pourcain et al.   MOLECULAR PSYCHIATRY

Transcriptome alterations of prefrontal cortical parvalbumin neurons in schizophrenia

(2017) J F Enwright III et al.   MOLECULAR PSYCHIATRY

Layered-up regulation in the developing brain

(2017)   NATURE

Regulation of neuronal survival by DNA methyltransferases

(2017) Geraldine Zimmer et al.   Neural Regeneration Research

CpG and Non-CpG Methylation in Epigenetic Gene Regulation and Brain Function

(2017) et al.   Genes

The DNA Methyltransferase 1 (DNMT1) Controls the Shape and Dynamics of Migrating POA-Derived Interneurons Fated for the Murine Cerebral Cortex

(2016) Daniel Pensold et al.   CEREBRAL CORTEX

Dynamic DNA methylation controls glutamate receptor trafficking and synaptic scaling

(2016) J. David Sweatt   JOURNAL OF NEUROCHEMISTRY

DNA Methyltransferase 1 Is Indispensable for Development of the Hippocampal Dentate Gyrus

(2016) Hirofumi Noguchi et al.   JOURNAL OF NEUROSCIENCE

Impact of DNMT1 and DNMT3a forebrain knockout on depressive- and anxiety like behavior in mice

(2016) Michael J. Morris et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

GABAergic Interneurons in the Neocortex: From Cellular Properties to Circuits

(2016) Robin Tremblay et al.   NEURON

Dynamic DNA methylation regulates neuronal intrinsic membrane excitability

(2016) Jarrod P. Meadows et al.   Science Signaling

Multisensory Processes: A Balancing Act across the Lifespan

(2016) Micah M. Murray et al.   TRENDS IN NEUROSCIENCES

Dynamic DNA methylation regulates neuronal intrinsic membrane excitability

(2016) Jarrod P. Meadows et al.   Science Signaling

Integration of electrophysiological recordings with single-cell RNA-seq data identifies neuronal subtypes

(2015) János Fuzik et al.   NATURE BIOTECHNOLOGY

Electrophysiological, transcriptomic and morphologic profiling of single neurons using Patch-seq

(2015) Cathryn R Cadwell et al.   NATURE BIOTECHNOLOGY

Tet3 regulates synaptic transmission and homeostatic plasticity via DNA oxidation and repair

(2015) Huimei Yu et al.   NATURE NEUROSCIENCE

The neuropathology of schizophrenia: A selective review of past studies and emerging themes in brain structure and cytoarchitecture

(2015) K. Bakhshi et al.   NEUROSCIENCE

The GABA System in Schizophrenia: Cells, Molecules and Microcircuitry

(2015) Francine M. Benes   SCHIZOPHRENIA RESEARCH

DNA-methyltransferase1 (DNMT1) binding to CpG rich GABAergic and BDNF promoters is increased in the brain of schizophrenia and bipolar disorder patients

(2015) E. Dong et al.   SCHIZOPHRENIA RESEARCH

DNA methylation regulates neuronal glutamatergic synaptic scaling

(2015) Jarrod P. Meadows et al.   Science Signaling

DNA methylation regulates neuronal glutamatergic synaptic scaling

(2015) Jarrod P. Meadows et al.   Science Signaling

Familial Recurrence of Autism Spectrum Disorder: Evaluating Genetic and Environmental Contributions

(2014) Neil Risch et al.   AMERICAN JOURNAL OF PSYCHIATRY

Reversing DNA Methylation: Mechanisms, Genomics, and Biological Functions

(2014) Hao Wu et al.   CELL

TET enzymes and DNA hydroxymethylation in neural development and function — How critical are they?

(2014) Mafalda Santiago et al.   GENOMICS

How does Reelin control neuronal migration and layer formation in the developing mammalian neocortex?

(2014) Katsutoshi Sekine et al.   NEUROSCIENCE RESEARCH

The long non-coding RNA Dali is an epigenetic regulator of neural differentiation

(2014) Vladislava Chalei et al.   eLife

Genome-wide DNA methylation analysis of human brain tissue from schizophrenia patients

(2014) L F Wockner et al.   Translational Psychiatry

Gene × Environment Interactions in Autism Spectrum Disorders: Role of Epigenetic Mechanisms

(2014) Sylvie Tordjman et al.   Frontiers in Psychiatry

Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition

(2013) Alika K Maunakea et al.   CELL RESEARCH

TET enzymes, TDG and the dynamics of DNA demethylation

(2013) Rahul M. Kohli et al.   NATURE

DNA methylation: roles in mammalian development

(2013) Zachary D. Smith et al.   NATURE REVIEWS GENETICS

New insights into the classification and nomenclature of cortical GABAergic interneurons

(2013) Javier DeFelipe et al.   NATURE REVIEWS NEUROSCIENCE

Cellular and Synaptic Architecture of Multisensory Integration in the Mouse Neocortex

(2013) Umberto Olcese et al.   NEURON

TET1 Controls CNS 5-Methylcytosine Hydroxylation, Active DNA Demethylation, Gene Transcription, and Memory Formation

(2013) Garrett A. Kaas et al.   NEURON

Tet1 Is Critical for Neuronal Activity-Regulated Gene Expression and Memory Extinction

(2013) Andrii Rudenko et al.   NEURON

Differential gene body methylation and reduced expression of cell adhesion and neurotransmitter receptor genes in adverse maternal environment

(2013) J-e Oh et al.   Translational Psychiatry

Interneuron dysfunction in psychiatric disorders

(2012) Oscar Marín   NATURE REVIEWS NEUROSCIENCE

Epigenetic modifications of GABAergic interneurons are associated with the schizophrenia-like phenotype induced by prenatal stress in mice

(2012) Francesco Matrisciano et al.   NEUROPHARMACOLOGY

The Dynamics of DNA Methylation in Schizophrenia and Related Psychiatric Disorders

(2012) Dennis R Grayson et al.   NEUROPSYCHOPHARMACOLOGY

GABA system dysfunction in autism and related disorders: From synapse to symptoms

(2012) Suzanne Coghlan et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Dnmt1-dependent DNA methylation is essential for photoreceptor terminal differentiation and retinal neuron survival

(2012) K-D Rhee et al.   Cell Death & Disease

Common genetic variants, acting additively, are a major source of risk for autism

(2012) Lambertus Klei et al.   Molecular Autism

Upregulation of TET1 and downregulation of APOBEC3A and APOBEC3C in the parietal cortex of psychotic patients

(2012) E Dong et al.   Translational Psychiatry

Epilepsy and Autism: Neurodevelopmental Perspective

(2011) Roberto Tuchman et al.   Current Neurology and Neuroscience Reports

Epigenetic Regulation of Motor Neuron Cell Death through DNA Methylation

(2011) B. A. Chestnut et al.   JOURNAL OF NEUROSCIENCE

Neuronal activity modifies the DNA methylation landscape in the adult brain

(2011) Junjie U Guo et al.   NATURE NEUROSCIENCE

Reelin Regulates Cadherin Function via Dab1/Rap1 to Control Neuronal Migration and Lamination in the Neocortex

(2011) Santos J. Franco et al.   NEURON

Epigenetic Regulation of Gene Expression in Physiological and Pathological Brain Processes

(2011) Johannes Gräff et al.   PHYSIOLOGICAL REVIEWS

Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine

(2011) S. Ito et al.   SCIENCE

Three groups of interneurons account for nearly 100% of neocortical GABAergic neurons

(2010) Bernardo Rudy et al.   Developmental Neurobiology

DNA methylation changes in schizophrenia and bipolar disorder

(2010) Caroline M. Connor et al.   Epigenetics

Conserved role of intragenic DNA methylation in regulating alternative promoters

(2010) Alika K. Maunakea et al.   NATURE

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

(2010) Hsiao-Tuan Chao et al.   NATURE

Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons

(2010) Jian Feng et al.   NATURE NEUROSCIENCE

Epigenetic GABAergic targets in schizophrenia and bipolar disorder

(2010) A. Guidotti et al.   NEUROPHARMACOLOGY

The environment and susceptibility to schizophrenia

(2010) Alan S. Brown   PROGRESS IN NEUROBIOLOGY

DNA hypomethylation restricted to the murine forebrain induces cortical degeneration and impairs postnatal neuronal maturation

(2009) Leah K. Hutnick et al.   HUMAN MOLECULAR GENETICS

Common circuit defect of excitatory-inhibitory balance in mouse models of autism

(2009) Nadine Gogolla et al.   Journal of Neurodevelopmental Disorders

An upregulation of DNA-methyltransferase 1 and 3a expressed in telencephalic GABAergic neurons of schizophrenia patients is also detected in peripheral blood lymphocytes

(2009) A. Zhubi et al.   SCHIZOPHRENIA RESEARCH

Activity-Dependent Suppression of Miniature Neurotransmission through the Regulation of DNA Methylation

(2008) E. D. Nelson et al.   JOURNAL OF NEUROSCIENCE

Failure of neuronal homeostasis results in common neuropsychiatric phenotypes

(2008) Melissa B. Ramocki et al.   NATURE

Neuroligins and neurexins link synaptic function to cognitive disease

(2008) Thomas C. Südhof   NATURE

Neuronal Diversity and Temporal Dynamics: The Unity of Hippocampal Circuit Operations

(2008) T. Klausberger et al.   SCIENCE

Early Defects of GABAergic Synapses in the Brain Stem of a MeCP2 Mouse Model of Rett Syndrome

(2007) L. Medrihan et al.   JOURNAL OF NEUROPHYSIOLOGY