A Review of Translational Magnetic Resonance Imaging in Human and Rodent Experimental Models of Small Vessel Disease

Perivascular spaces in the brain: anatomy, physiology and pathology

(2020) Joanna M. Wardlaw et al.   Nature Reviews Neurology

Optimal Mass Transport with Lagrangian Workflow Reveals Advective and Diffusion Driven Solute Transport in the Glymphatic System

(2020) Sunil Koundal et al.   Scientific Reports

APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline

(2020) Axel Montagne et al.   NATURE

Blood–brain barrier breakdown is an early biomarker of human cognitive dysfunction

(2019) Daniel A. Nation et al.   NATURE MEDICINE

1H-MRS Quantitation of Age-Dependent Taurine Changes in Mouse Brain

(2019) Mingming Zhu et al.   MOLECULAR IMAGING AND BIOLOGY

Methodological consensus on clinical proton MRS of the brain: Review and recommendations

(2019) Martin Wilson et al.   MAGNETIC RESONANCE IN MEDICINE

Measuring Glymphatic Flow in Man Using Quantitative Contrast-Enhanced MRI

(2019) R. Watts et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Quantifying blood-brain barrier leakage in small vessel disease: Review and consensus recommendations

(2019) Michael J. Thrippleton et al.   Alzheimers & Dementia

Glymphatic System Function in Relation to Anesthesia and Sleep States

(2019) Helene Benveniste et al.   ANESTHESIA AND ANALGESIA

Small vessel disease: mechanisms and clinical implications

(2019) Joanna M Wardlaw et al.   LANCET NEUROLOGY

Preventing dementia by preventing stroke: The Berlin Manifesto

(2019) Vladimir Hachinski et al.   Alzheimers & Dementia

Perfusion fixation in brain banking: a systematic review

(2019) Whitney C. McFadden et al.   Acta Neuropathologica Communications

The role of brain barriers in fluid movement in the CNS: is there a ‘glymphatic’ system?

(2018) N. Joan Abbott et al.   ACTA NEUROPATHOLOGICA

Age and sex-specific associations of carotid pulsatility with small vessel disease burden in transient ischemic attack and ischemic stroke

(2018) Kui Kai Lau et al.   International Journal of Stroke

Non-contrast MR imaging of blood-brain barrier permeability to water

(2018) Zixuan Lin et al.   MAGNETIC RESONANCE IN MEDICINE

Pericyte degeneration causes white matter dysfunction in the mouse central nervous system

(2018) Axel Montagne et al.   NATURE MEDICINE

Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders

(2018) Melanie D. Sweeney et al.   Nature Reviews Neurology

Vascular reactivity in small cerebral perforating arteries with 7 T phase contrast MRI – A proof of concept study

(2018) Lennart J. Geurts et al.   NEUROIMAGE

Linking brain vascular physiology to hemodynamic response in ultra-high field MRI

(2018) Kâmil Uludağ et al.   NEUROIMAGE

A protocol for precise comparisons of small vessel disease lesions between ex vivo magnetic resonance imaging and histopathology

(2018) Catherine A Humphreys et al.   International Journal of Stroke

Post-mortem magnetic resonance imaging in patients with suspected prion disease: Pathological confirmation, sensitivity, specificity and observer reliability. A national registry

(2018) Lorna M. Gibson et al.   PLoS One

Non-invasive imaging of CSF-mediated brain clearance pathways via assessment of perivascular fluid movement with diffusion tensor MRI

(2018) Ian F Harrison et al.   eLife

Deuterium metabolic imaging (DMI) for MRI-based 3D mapping of metabolism in vivo

(2018) Henk M. De Feyter et al.   Science Advances

Small vessel disease is associated with altered cerebrovascular pulsatility but not resting cerebral blood flow

(2018) Yulu Shi et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Flow of cerebrospinal fluid is driven by arterial pulsations and is reduced in hypertension

(2018) Humberto Mestre et al.   Nature Communications

Modeling glymphatic system of the brain using MRI

(2018) Esmaeil Davoodi-Bojd et al.   NEUROIMAGE

Non-invasive MRI of brain clearance pathways using multiple echo time arterial spin labelling: an aquaporin-4 study

(2018) Yolanda Ohene et al.   NEUROIMAGE

Cerebrovascular reactivity measurement in cerebral small vessel disease: Rationale and reproducibility of a protocol for MRI acquisition and image processing

(2017) Michael J Thrippleton et al.   International Journal of Stroke

The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments)

(2017) Nathalie Percie du Sert et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Experimental chronic cerebral hypoperfusion results in decreased pericyte coverage and increased blood–brain barrier permeability in the corpus callosum

(2017) Qinghai Liu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Collagenosis of the Deep Medullary Veins: An Underrecognized Pathologic Correlate of White Matter Hyperintensities and Periventricular Infarction?

(2017) Julia Keith et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Detection, risk factors, and functional consequences of cerebral microinfarcts

(2017) Susanne J van Veluw et al.   LANCET NEUROLOGY

Pericyte degeneration leads to neurovascular uncoupling and limits oxygen supply to brain

(2017) Kassandra Kisler et al.   NATURE NEUROSCIENCE

Col4a1 mutation generates vascular abnormalities correlated with neuronal damage in a mouse model of HANAC syndrome

(2017) Alix Trouillet et al.   NEUROBIOLOGY OF DISEASE

Cerebrospinal and interstitial fluid transport via the glymphatic pathway modeled by optimal mass transport

(2017) Vadim Ratner et al.   NEUROIMAGE

Diagnostic performance of susceptibility-weighted magnetic resonance imaging for the detection of calcifications: A systematic review and meta-analysis

(2017) Lisa C. Adams et al.   Scientific Reports

Human and nonhuman primate meninges harbor lymphatic vessels that can be visualized noninvasively by MRI

(2017) Martina Absinta et al.   eLife

Test of the 'glymphatic' hypothesis demonstrates diffusive and aquaporin-4-independent solute transport in rodent brain parenchyma

(2017) Alex J Smith et al.   eLife

Brain imaging of neurovascular dysfunction in Alzheimer’s disease

(2016) Axel Montagne et al.   ACTA NEUROPATHOLOGICA

Post-mortem assessment in vascular dementia: advances and aspirations

(2016) Kirsty E. McAleese et al.   BMC Medicine

Microbleed and microinfarct detection in amyloid angiopathy: a high-resolution MRI-histopathology study

(2016) Susanne J. van Veluw et al.   BRAIN

Comparison of seven different anesthesia protocols for nicotine pharmacologic magnetic resonance imaging in rat

(2016) Jaakko Paasonen et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Magnetic resonance imaging for assessment of cerebrovascular reactivity in cerebral small vessel disease: A systematic review

(2016) Gordon W Blair et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Impairment of the glymphatic system after diabetes

(2016) Quan Jiang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Reproducibility and variability of quantitative magnetic resonance imaging markers in cerebral small vessel disease

(2016) François De Guio et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Cerebral blood flow in small vessel disease: A systematic review and meta-analysis

(2016) Yulu Shi et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Diagnostic quality assessment of compressed sensing accelerated magnetic resonance neuroimaging

(2016) Mohammad Kayvanrad et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Longitudinal noninvasive magnetic resonance imaging of brain microhemorrhages in BACE inhibitor–treated APP transgenic mice

(2016) Nicolau Beckmann et al.   NEUROBIOLOGY OF AGING

Suppression of glymphatic fluid transport in a mouse model of Alzheimer's disease

(2016) Weiguo Peng et al.   NEUROBIOLOGY OF DISEASE

Tracer kinetic modelling for DCE-MRI quantification of subtle blood–brain barrier permeability

(2016) Anna K. Heye et al.   NEUROIMAGE

Blood-Brain Barrier Leakage in Patients with Early Alzheimer Disease

(2016) Harm J. van de Haar et al.   RADIOLOGY

Neuroimaging as a Selection Tool and Endpoint in Clinical and Pre-clinical Trials

(2016) Keith W. Muir et al.   Translational Stroke Research

Rodent Models of Vascular Cognitive Impairment

(2016) Yi Yang et al.   Translational Stroke Research

Cerebral blood flow and autoregulation: current measurement techniques and prospects for noninvasive optical methods

(2016) Sergio Fantini et al.   Neurophotonics

Cerebrovascular and blood-brain barrier impairments in Huntington's disease: Potential implications for its pathophysiology

(2015) Janelle Drouin-Ouellet et al.   ANNALS OF NEUROLOGY

Establishment and Dysfunction of the Blood-Brain Barrier

(2015) Zhen Zhao et al.   CELL

The Significance of Cortical Cerebellar Microbleeds and Microinfarcts in Neurodegenerative and Cerebrovascular Diseases

(2015) Jacques L. De Reuck et al.   CEREBROVASCULAR DISEASES

Consensus statement for diagnosis of subcortical small vessel disease

(2015) Gary A Rosenberg et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Spectrum of MR Detectable Cortical Microinfarcts: A Classification Study with 7-Tesla Postmortem MRI and Histopathology

(2015) Susanne J van Veluw et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Gliovascular Disruption and Cognitive Deficits in a Mouse Model with Features of Small Vessel Disease

(2015) Philip R Holland et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Ultra-fast magnetic resonance encephalography of physiological brain activity – Glymphatic pulsation mechanisms?

(2015) Vesa Kiviniemi et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Water Exchange across the Blood-Brain Barrier in Obstructive Sleep Apnea: An MRI Diffusion-Weighted Pseudo-Continuous Arterial Spin Labeling Study

(2015) Jose A. Palomares et al.   JOURNAL OF NEUROIMAGING

The Effect of Body Posture on Brain Glymphatic Transport

(2015) H. Lee et al.   JOURNAL OF NEUROSCIENCE

Morphologic Changes of Cerebral Veins in Hypertensive Rats: Venous Collagenosis Is Associated with Hypertension

(2015) Min Zhou et al.   Journal of Stroke & Cerebrovascular Diseases

Optimal acquisition and modeling parameters for accurate assessment of low Ktransblood-brain barrier permeability using dynamic contrast-enhanced MRI

(2015) Samuel R. Barnes et al.   MAGNETIC RESONANCE IN MEDICINE

Clearance systems in the brain—implications for Alzheimer disease

(2015) Jenna M. Tarasoff-Conway et al.   Nature Reviews Neurology

Cerebral angiography, blood flow and vascular reactivity in progressive hypertension

(2015) Yunxia Li et al.   NEUROIMAGE

Blood-Brain Barrier Breakdown in the Aging Human Hippocampus

(2015) Axel Montagne et al.   NEURON

ROCKETSHIP: a flexible and modular software tool for the planning, processing and analysis of dynamic MRI studies

(2015) Samuel R. Barnes et al.   BMC MEDICAL IMAGING

Morphologic Changes of Cerebral Veins in Hypertensive Rats: Venous Collagenosis Is Associated with Hypertension

(2015) Min Zhou et al.   Journal of Stroke & Cerebrovascular Diseases

Considerations for resting state functional MRI and functional connectivity studies in rodents

(2015) Wen-Ju Pan et al.   Frontiers in Neuroscience

Recommended implementation of arterial spin-labeled perfusion MRI for clinical applications: A consensus of the ISMRM perfusion study group and the European consortium for ASL in dementia

(2014) David C. Alsop et al.   MAGNETIC RESONANCE IN MEDICINE

Systematic Review and Meta-Analysis of Interventions Tested in Animal Models of Lacunar Stroke

(2014) Hugo Pedder et al.   STROKE

Spontaneous white matter damage, cognitive decline and neuroinflammation in middle-aged hypertensive rats: an animal model of early-stage cerebral small vessel disease

(2014) Daniel Kaiser et al.   Acta Neuropathologica Communications

Morphologic, Distributional, Volumetric, and Intensity Characterization of Periventricular Hyperintensities

(2013) M.C. Valdés Hernández et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Comparison of Cerebral Vascular Reactivity Measures Obtained Using Breath-Holding and CO2 Inhalation

(2013) Felipe B Tancredi et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Regional Cerebral Blood Flow and Arterial Blood Volume and Their Reactivity to Hypercapnia in Hypertensive and Normotensive Rats

(2013) Tae Kim et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Brain-wide pathway for waste clearance captured by contrast-enhanced MRI

(2013) Jeffrey J. Iliff et al.   JOURNAL OF CLINICAL INVESTIGATION

Proton MRS in mild cognitive impairment

(2013) Kejal Kantarci   JOURNAL OF MAGNETIC RESONANCE IMAGING

Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration

(2013) Joanna M Wardlaw et al.   LANCET NEUROLOGY

Voxel-based morphometry with templates and validation in a mouse model of Huntington’s disease

(2013) Stephen J. Sawiak et al.   MAGNETIC RESONANCE IMAGING

Glutamate and glutamine: a review ofin vivoMRS in the human brain

(2013) Saadallah Ramadan et al.   NMR IN BIOMEDICINE

BOLD fMRI in the White Matter as a Marker of Aging and Small Vessel Disease

(2013) Ilia Makedonov et al.   PLoS One

Cerebral venous system and anatomical predisposition to high-altitude headache

(2012) Mark H. Wilson et al.   ANNALS OF NEUROLOGY

Dynamic contrast-enhanced imaging techniques: CT and MRI

(2012) J P B O'Connor et al.   BRITISH JOURNAL OF RADIOLOGY

pH as a Biomarker of Neurodegeneration in Huntington's Disease: A Translational Rodent-Human MRS Study

(2012) Myriam M Chaumeil et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Parallel MR imaging

(2012) Anagha Deshmane et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

MR spectroscopic imaging: Principles and recent advances

(2012) Stefan Posse et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

A Quantitative Postmortem MRI Design Sensitive to White Matter Hyperintensity Differences and Their Relationship With Underlying Pathology

(2012) Melissa E. Murray et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Cerebral microinfarcts: the invisible lesions

(2012) Eric E Smith et al.   LANCET NEUROLOGY

Apolipoprotein E controls cerebrovascular integrity via cyclophilin A

(2012) Robert D. Bell et al.   NATURE

Magnetic resonance imaging of fixedpost mortembrains reliably reflects subcortical vascular pathology of frontal, parietal and occipital white matter

(2012) K. E. McAleese et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid  

(2012) J. J. Iliff et al.   Science Translational Medicine

Preclinical 1H-MRS neurochemical profiling in neurological and psychiatric disorders

(2012) Moonnoh R Lee et al.   Bioanalysis

Practical Dynamic Contrast Enhanced MRI in Small Animal Models of Cancer: Data Acquisition, Data Analysis, and Interpretation

(2012) Stephanie L. Barnes et al.   Pharmaceutics

Cerebral Microbleeds: Histopathological Correlation of Neuroimaging

(2011) A. Shoamanesh et al.   CEREBROVASCULAR DISEASES

Comparison of 7.0-T T2*-Magnetic Resonance Imaging of Cerebral Bleeds in Post-Mortem Brain Sections of Alzheimer Patients with Their Neuropathological Correlates

(2011) J. De Reuck et al.   CEREBROVASCULAR DISEASES

Probing Cerebrovascular Alterations in Alzheimers Disease Using MRI: From Transgenic Models to Patients

(2011) Nicolau Beckmann   Current Medical Imaging Reviews

Is the Spontaneously Hypertensive Stroke Prone Rat a Pertinent Model of Sub Cortical Ischemic Stroke? A Systematic Review

(2011) Emma L. Bailey et al.   International Journal of Stroke

Detection of Cerebral Microbleeds with Quantitative Susceptibility Mapping in the Arcabeta Mouse Model of Cerebral Amyloidosis

(2011) Jan Klohs et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

MRI artifacts in human brain tissue after prolonged formalin storage

(2011) Sara van Duijn et al.   MAGNETIC RESONANCE IN MEDICINE

Magnetic resonance imaging quantification of regional cerebral blood flow and cerebrovascular reactivity to carbon dioxide in normotensive and hypertensive rats

(2011) Renata F. Leoni et al.   NEUROIMAGE

Cytoprotective protein C pathways and implications for stroke and neurological disorders

(2011) Berislav V. Zlokovic et al.   TRENDS IN NEUROSCIENCES

Ex Vivo Diffusion Tensor Imaging and Neuropathological Correlation in a Murine Model of Hypoxia–Ischemia-Induced Thrombotic Stroke

(2010) Ahmed Shereen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease

(2010) Anne Joutel et al.   JOURNAL OF CLINICAL INVESTIGATION

Magnetic Resonance Imaging Detection and Time Course of Cerebral Microhemorrhages during Passive Immunotherapy in Living Amyloid Precursor Protein Transgenic Mice

(2010) F. Luo et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Enhancing search efficiency by means of a search filter for finding all studies on animal experimentation in PubMed

(2010) Carlijn R Hooijmans et al.   LABORATORY ANIMALS

MRI is a sensitive marker of subtle white matter pathology in hypoperfused mice

(2010) Philip R. Holland et al.   NEUROBIOLOGY OF AGING

Recent Advances in Visualizing Alzheimers Plaques by Magnetic Resonance Imaging

(2009) Niels Braakman et al.   Current Medical Imaging Reviews

MRI and histological analysis of beta-amyloid plaques in both human Alzheimer's disease and APP/PS1 transgenic mice

(2009) Mark D. Meadowcroft et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Postmortem MRI of human brain hemispheres:T2relaxation times during formaldehyde fixation

(2009) Robert J. Dawe et al.   MAGNETIC RESONANCE IN MEDICINE

Aldehyde fixative solutions alter the water relaxation and diffusion properties of nervous tissue

(2009) Timothy M. Shepherd et al.   MAGNETIC RESONANCE IN MEDICINE

Brain temperature and pH measured by1H chemical shift imaging of a thulium agent

(2009) Daniel Coman et al.   NMR IN BIOMEDICINE

Do in vivo Experimental Models Reflect Human Cerebral Small Vessel Disease? a Systematic Review

(2008) Atticus H Hainsworth et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Diffusion tensor imaging and MR spectroscopy in hypertension and presumed cerebral small vessel disease

(2008) Arani Nitkunan et al.   MAGNETIC RESONANCE IN MEDICINE

Neuropathologic correlates of white matter hyperintensities

(2008) V. G. Young et al.   NEUROLOGY

Understanding White Matter Disease: Imaging-Pathological Correlations in Vascular Cognitive Impairment

(2008) S. Black et al.   STROKE

Improving Interrater Agreement About Brain Microbleeds

(2008) Charlotte Cordonnier et al.   STROKE

Blood–brain barrier: Ageing and microvascular disease – systematic review and meta-analysis

(2007) Andrew J. Farrall et al.   NEUROBIOLOGY OF AGING