Human cytomegalovirus evades ZAP detection by suppressing CpG dinucleotides in the major immediate early 1 gene

The interplay between viruses and TRIM family proteins

(2019) Ramisha Khan et al.   REVIEWS IN MEDICAL VIROLOGY

Impact of CMV upon immune aging: facts and fiction

(2019) Mladen Jergović et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

The role of ZAP and OAS3/RNAseL pathways in the attenuation of an RNA virus with elevated frequencies of CpG and UpA dinucleotides

(2019) Valerie Odon et al.   NUCLEIC ACIDS RESEARCH

KHNYN is essential for the zinc finger antiviral protein (ZAP) to restrict HIV-1 containing clustered CpG dinucleotides

(2019) Mattia Ficarelli et al.   eLife

Structure of the zinc-finger antiviral protein in complex with RNA reveals a mechanism for selective targeting of CG-rich viral sequences

(2019) Jennifer L. Meagher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interferon-Stimulated Gene (ISG)-Expression Screening Reveals the Specific Antibunyaviral Activity of ISG20

(2018) Junjie Feng et al.   JOURNAL OF VIROLOGY

Inhibition of Japanese encephalitis virus infection by the host zinc-finger antiviral protein

(2018) Hsin-Ping Chiu et al.   PLoS Pathogens

TRIM25 Is Required for the Antiviral Activity of Zinc Finger Antiviral Protein

(2017) Xiaojiao Zheng et al.   JOURNAL OF VIROLOGY

CG dinucleotide suppression enables antiviral defence targeting non-self RNA

(2017) Matthew A. Takata et al.   NATURE

Fundamental properties of the mammalian innate immune system revealed by multispecies comparison of type I interferon responses

(2017) Andrew E. Shaw et al.   PLOS BIOLOGY

TRIM25 Enhances the Antiviral Action of Zinc-Finger Antiviral Protein (ZAP)

(2017) Melody M. H. Li et al.   PLoS Pathogens

Identification of Interferon-Stimulated Genes with Antiretroviral Activity

(2016) Melissa Kane et al.   Cell Host & Microbe

cGAS-STING Signaling Regulates Initial Innate Control of Cytomegalovirus Infection

(2016) Chan-Wang J. Lio et al.   JOURNAL OF VIROLOGY

Systemic inflammation after critical illness: relationship with physical recovery and exploration of potential mechanisms

(2016) David M Griffith et al.   THORAX

Viral DNA Sensors IFI16 and Cyclic GMP-AMP Synthase Possess Distinct Functions in Regulating Viral Gene Expression, Immune Defenses, and Apoptotic Responses during Herpesvirus Infection

(2016) Benjamin A. Diner et al.   mBio

cGAS Senses Human Cytomegalovirus and Induces Type I Interferon Responses in Human Monocyte-Derived Cells

(2016) Jennifer Paijo et al.   PLoS Pathogens

Elevation of CpG frequencies in influenza A genome attenuates pathogenicity but enhances host response to infection

(2016) Eleanor Gaunt et al.   eLife

Zinc finger antiviral protein inhibits coxsackievirus B3 virus replication and protects against viral myocarditis

(2015) Min Li et al.   ANTIVIRAL RESEARCH

A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation

(2015) Meike Dittmann et al.   CELL

Battle between influenza A virus and a newly identified antiviral activity of the PARP-containing ZAPL protein

(2015) Chien-Hung Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Herpes simplex virus 1 UL41 protein abrogates the antiviral activity of hZAP by degrading its mRNA

(2015) Chenhe Su et al.   Virology Journal

Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging Alphaviruses

(2015) Tina M. Sali et al.   PLoS Pathogens

Differential Initiation of Innate Immune Responses Induced by Human Cytomegalovirus Entry into Fibroblast Cells

(2014) L. K. Juckem et al.   JOURNAL OF IMMUNOLOGY

The influence of CpG and UpA dinucleotide frequencies on RNA virus replication and characterization of the innate cellular pathways underlying virus attenuation and enhanced replication

(2014) Nicky J. Atkinson et al.   NUCLEIC ACIDS RESEARCH

Activation of Nucleotide Oligomerization Domain 2 (NOD2) by Human Cytomegalovirus Initiates Innate Immune Responses and Restricts Virus Replication

(2014) Arun Kapoor et al.   PLoS One

Trim25 Is an RNA-Specific Activator of Lin28a/TuT4-Mediated Uridylation

(2014) Nila Roy Choudhury et al.   Cell Reports

CMV: Prevention, Diagnosis and Therapy

(2013) C. N. Kotton   AMERICAN JOURNAL OF TRANSPLANTATION

Modelling mutational and selection pressures on dinucleotides in eukaryotic phyla –selection against CpG and UpA in cytoplasmically expressed RNA and in RNA viruses

(2013) Peter Simmonds et al.   BMC GENOMICS

Checks and balances between human cytomegalovirus replication and indoleamine-2,3-dioxygenase

(2013) A. Zimmermann et al.   JOURNAL OF GENERAL VIROLOGY

The Tiers and Dimensions of Evasion of the Type I Interferon Response by Human Cytomegalovirus

(2013) Lisi Amsler et al.   JOURNAL OF MOLECULAR BIOLOGY

Prevention of cytomegalovirus following solid organ transplantation: A literature review

(2013) Shanna Kowalsky et al.   PEDIATRIC TRANSPLANTATION

Inhibition of Hepatitis B Virus Replication by the Host Zinc Finger Antiviral Protein

(2013) Richeng Mao et al.   PLoS Pathogens

Translational repression precedes and is required for ZAP-mediated mRNA decay

(2012) Yiping Zhu et al.   EMBO JOURNAL

Severe impairment of IFN-  and IFN-  responses in cells of a patient with a novel STAT1 splicing mutation

(2011) D. Vairo et al.   BLOOD

Interferon Successfully Inhibited Refractory Cytomegalovirus Infection and Resulted in CD4+ T-cells Increase in a Patient with AIDS

(2011) Ying Wen et al.   HIV CLINICAL TRIALS

Pathogen Recognition by the Innate Immune System

(2011) Himanshu Kumar et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

A diverse range of gene products are effectors of the type I interferon antiviral response

(2011) John W. Schoggins et al.   NATURE

Zinc-finger antiviral protein inhibits HIV-1 infection by selectively targeting multiply spliced viral mRNAs for degradation

(2011) Y. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Novel Human Cytomegalovirus Locus Modulates Cell Type-Specific Outcomes of Infection

(2011) Mahadevaiah Umashankar et al.   PLoS Pathogens

ZAPS is a potent stimulator of signaling mediated by the RNA helicase RIG-I during antiviral responses

(2010) Sumio Hayakawa et al.   NATURE IMMUNOLOGY

Human Cytomegalovirus Induces the Interferon Response via the DNA Sensor ZBP1

(2009) V. R. DeFilippis et al.   JOURNAL OF VIROLOGY

Positive Selection and Increased Antiviral Activity Associated with the PARP-Containing Isoform of Human Zinc-Finger Antiviral Protein

(2008) Julie A. Kerns et al.   PLoS Genetics