The influence of CpG and UpA dinucleotide frequencies on RNA virus replication and characterization of the innate cellular pathways underlying virus attenuation and enhanced replication

Small molecule modulators of eukaryotic initiation factor 2α kinases, the key regulators of protein synthesis

(2013) Manali Joshi et al.   BIOCHIMIE

Modelling mutational and selection pressures on dinucleotides in eukaryotic phyla –selection against CpG and UpA in cytoplasmically expressed RNA and in RNA viruses

(2013) Peter Simmonds et al.   BMC GENOMICS

The role of mutational robustness in RNA virus evolution

(2013) Adam S. Lauring et al.   NATURE REVIEWS MICROBIOLOGY

Enterovirus 71 Protease 2Apro Targets MAVS to Inhibit Anti-Viral Type I Interferon Responses

(2013) Bei Wang et al.   PLoS Pathogens

Codon Usage Determines the Mutational Robustness, Evolutionary Capacity, and Virulence of an RNA Virus

(2012) Adam S. Lauring et al.   Cell Host & Microbe

Enterovirus 71 Disrupts Interferon Signaling by Reducing the Level of Interferon Receptor 1

(2012) J. Lu et al.   JOURNAL OF VIROLOGY

The Biased Nucleotide Composition of HIV-1 Triggers Type I Interferon Response and Correlates with Subtype D Increased Pathogenicity

(2012) Nicolas Vabret et al.   PLoS One

The biased nucleotide composition of the HIV genome: a constant factor in a highly variable virus

(2012) Antoinette C van der Kuyl et al.   Retrovirology

A functional nuclear localization sequence in the VP1 capsid protein of coxsackievirus B3

(2012) Tianying Wang et al.   VIROLOGY

MDA5 Detects the Double-Stranded RNA Replicative Form in Picornavirus-Infected Cells

(2012) Qian Feng et al.   Cell Reports

The TLR3/TICAM-1 Pathway Is Mandatory for Innate Immune Responses to Poliovirus Infection

(2011) Hiroyuki Oshiumi et al.   JOURNAL OF IMMUNOLOGY

The Fitness Effects of Synonymous Mutations in DNA and RNA Viruses

(2011) José M. Cuevas et al.   MOLECULAR BIOLOGY AND EVOLUTION

Adenosine deaminases acting on RNA (ADARs) are both antiviral and proviral

(2011) Charles E. Samuel   VIROLOGY

A detailed comparative analysis on the overall codon usage patterns in Hepatitis A virus

(2011) Lucía D’ Andrea et al.   VIRUS RESEARCH

Disruption of TLR3 Signaling Due to Cleavage of TRIF by the Hepatitis A Virus Protease-Polymerase Processing Intermediate, 3CD

(2011) Lin Qu et al.   PLoS Pathogens

Genetic Inactivation of Poliovirus Infectivity by Increasing the Frequencies of CpG and UpA Dinucleotides within and across Synonymous Capsid Region Codons

(2009) C. C. Burns et al.   JOURNAL OF VIROLOGY

Activation of MDA5 Requires Higher-Order RNA Structures Generated during Virus Infection

(2009) A. Pichlmair et al.   JOURNAL OF VIROLOGY

Patterns of Oligonucleotide Sequences in Viral and Host Cell RNA Identify Mediators of the Host Innate Immune System

(2009) Benjamin D. Greenbaum et al.   PLoS One

Virus-Host Coevolution: Common Patterns of Nucleotide Motif Usage in Flaviviridae and Their Hosts

(2009) Francisco P. Lobo et al.   PLoS One

RIG-I is cleaved during picornavirus infection

(2009) Paola M. Barral et al.   VIROLOGY

CAIcal: A combined set of tools to assess codon usage adaptation

(2008) Pere Puigbò et al.   Biology Direct

A chemical compound commonly used to inhibit PKR, {8-(imidazol-4-ylmethylene)-6H-azolidino[5,4-g] benzothiazol-7-one}, protects neurons by inhibiting cyclin-dependent kinase

(2008) Hsin-Mei Chen et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Genome-scale relationships between cytosine methylation and dinucleotide abundances in animals

(2008) Martin W. Simmen   GENOMICS

DNA vaccines: developing new strategies to enhance immune responses

(2008) Shaheed A. Abdulhaqq et al.   IMMUNOLOGIC RESEARCH

Bioinformatic and functional analysis of RNA secondary structure elements among different genera of human and animal caliciviruses

(2008) Peter Simmonds et al.   NUCLEIC ACIDS RESEARCH

Virus Attenuation by Genome-Scale Changes in Codon Pair Bias

(2008) J. R. Coleman et al.   SCIENCE

Patterns of Evolution and Host Gene Mimicry in Influenza and Other RNA Viruses

(2008) Benjamin D. Greenbaum et al.   PLoS Pathogens