Platelets are versatile cells: New discoveries in hemostasis, thrombosis, immune responses, tumor metastasis and beyond

A-Disintegrin-And-Metalloproteinase (ADAM) 10 Activity on Resting and Activated Platelets

(2016) Adam Facey et al.   BIOCHEMISTRY

The prothrombotic activity of cancer cells in the circulation

(2016) Annachiara Mitrugno et al.   BLOOD REVIEWS

Fibronectin maintains the balance between hemostasis and thrombosis

(2016) Yiming Wang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Extracellular matrix proteins in the regulation of thrombus formation

(2016) Yiming Wang et al.   CURRENT OPINION IN HEMATOLOGY

Glucagon-Like Peptide 1 Receptor Activation Attenuates Platelet Aggregation and Thrombosis

(2016) Alison Cameron-Vendrig et al.   DIABETES

Platelet immunoreceptor tyrosine-based activation motif (ITAM) and hemITAM signaling and vascular integrity in inflammation and development

(2016) R. H. Lee et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Fetal and neonatal alloimmune thrombocytopenia

(2016) Darko Zdravic et al.   Seminars in Fetal & Neonatal Medicine

Translational approaches to functional platelet production ex vivo

(2016) Christian A. Di Buduo et al.   THROMBOSIS AND HAEMOSTASIS

Platelets, immune-mediated thrombocytopenias, and fetal hemorrhage

(2016) Xiaohong Ruby Xu et al.   THROMBOSIS RESEARCH

Sialidase inhibition to increase platelet counts: A new treatment option for thrombocytopenia

(2015) Arend Jan Gerard Jansen et al.   AMERICAN JOURNAL OF HEMATOLOGY

Current State and Novel Approaches of Antiplatelet Therapy

(2015) P. Metharom et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

CD8+ T cells are predominantly protective and required for effective steroid therapy in murine models of immune thrombocytopenia

(2015) L. Ma et al.   BLOOD

Dengue virus binding and replication by platelets

(2015) A. Y. Simon et al.   BLOOD

Interaction of kindlin-3 and  2-integrins differentially regulates neutrophil recruitment and NET release in mice

(2015) Z. Xu et al.   BLOOD

CD20+ B-cell depletion therapy suppresses murine CD8+ T-cell-mediated immune thrombocytopenia

(2015) L. Guo et al.   BLOOD

Fibronectin: extra domain brings extra risk?

(2015) Y. Wang et al.   BLOOD

Regulating billions of blood platelets: glycans and beyond

(2015) R. Grozovsky et al.   BLOOD

Platelets at the interface of thrombosis, inflammation, and cancer

(2015) A. T. Franco et al.   BLOOD

Comparative analysis of human ex vivo-generated platelets vs megakaryocyte-generated platelets in mice: a cautionary tale

(2015) Y. Wang et al.   BLOOD

Regulation of leucocyte homeostasis in the circulation

(2015) Christoph Scheiermann et al.   CARDIOVASCULAR RESEARCH

Efficacy and Harms of Direct Oral Anticoagulants in the Elderly for Stroke Prevention in Atrial Fibrillation and Secondary Prevention of Venous ThromboembolismCLINICAL PERSPECTIVE

(2015) Manuj Sharma et al.   CIRCULATION

Idarucizumab

(2015) John W. Eikelboom et al.   CIRCULATION

Heart Disease and Stroke Statistics—2016 Update

(2015) Dariush Mozaffarian et al.   CIRCULATION

The FDA report on vorapaxar in the elderly: A convoluted dilemma

(2015) Victor L. Serebruany et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

IL-1α induces thrombopoiesis through megakaryocyte rupture in response to acute platelet needs

(2015) Satoshi Nishimura et al.   JOURNAL OF CELL BIOLOGY

Maternal anti-platelet β3 integrins impair angiogenesis and cause intracranial hemorrhage

(2015) Issaka Yougbaré et al.   JOURNAL OF CLINICAL INVESTIGATION

Extracellular DNA and histones: double-edged swords in immunothrombosis

(2015) T. J. Gould et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Reincarnation of ancient links between coagulation and complement

(2015) E. M. Conway   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Platelet secretory behaviour: as diverse as the granules … or not?

(2015) H. Heijnen et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

MicroRNAs in platelet function and cardiovascular disease

(2015) David D. McManus et al.   Nature Reviews Cardiology

Thrombopoiesis

(2015) Kenneth Kaushansky   SEMINARS IN HEMATOLOGY

Low-dose decitabine promotes megakaryocyte maturation and platelet production in healthy controls and immune thrombocytopenia

(2015) Hai Zhou et al.   THROMBOSIS AND HAEMOSTASIS

Desialylation is a mechanism of Fc-independent platelet clearance and a therapeutic target in immune thrombocytopenia

(2015) June Li et al.   Nature Communications

The class II PI 3-kinase, PI3KC2α, links platelet internal membrane structure to shear-dependent adhesive function

(2015) Jessica K. Mountford et al.   Nature Communications

Angiogenesis and bleeding disorders in FNAIT

(2015) Issaka Yougbare et al.   Oncotarget

Fibronectin orchestrates thrombosis and hemostasis

(2015) Yiming Wang et al.   Oncotarget

New insights into the mechanisms of action of aspirin and its use in the prevention and treatment of arterial and venous thromboembolism

(2015) Agon Mekaj et al.   Therapeutics and Clinical Risk Management

Redundancy and Interaction of Thrombin- and Collagen-Mediated Platelet Activation in Tail Bleeding and Carotid Thrombosis in Mice

(2014) Yamini S. Bynagari-Settipalli et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Coronary thrombus composition: Links with inflammation, platelet and endothelial markers

(2014) Marcin Sadowski et al.   ATHEROSCLEROSIS

Thrombospondin 1 requires von Willebrand factor to modulate arterial thrombosis in mice

(2014) P. Prakash et al.   BLOOD

Thrombus formation reimagined

(2014) R. Flaumenhaft   BLOOD

A randomized trial of avatrombopag, an investigational thrombopoietin-receptor agonist, in persistent and chronic immune thrombocytopenia

(2014) J. B. Bussel et al.   BLOOD

Expansion of the neonatal platelet mass is achieved via an extension of platelet lifespan

(2014) Z.-J. Liu et al.   BLOOD

Aspirin for prevention and treatment of venous thromboembolism

(2014) Cecilia Becattini et al.   BLOOD REVIEWS

Milestones in understanding platelet production: a historical overview

(2014) David J. Kuter   BRITISH JOURNAL OF HAEMATOLOGY

The role of apoptosis in megakaryocytes and platelets

(2014) Benjamin T. Kile   BRITISH JOURNAL OF HAEMATOLOGY

Interpreting the developmental dance of the megakaryocyte: a review of the cellular and molecular processes mediating platelet formation

(2014) Kellie R. Machlus et al.   BRITISH JOURNAL OF HAEMATOLOGY

Targeting Activated Platelets and Fibrinolysis

(2014) Adili Reheman et al.   CIRCULATION RESEARCH

Living in shear: platelets protect cancer cells from shear induced damage

(2014) Karl Egan et al.   CLINICAL & EXPERIMENTAL METASTASIS

Severe platelet desialylation in a patient with glycoprotein Ib/IX antibody-mediated immune thrombocytopenia and fatal pulmonary hemorrhage

(2014) J. Li et al.   HAEMATOLOGICA

Clinical and Safety Outcomes Associated With Treatment of Acute Venous Thromboembolism

(2014) Lana A. Castellucci et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Plasma fibronectin supports hemostasis and regulates thrombosis

(2014) Yiming Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Platelet factor 4 limits Th17 differentiation and cardiac allograft rejection

(2014) Guanfang Shi et al.   JOURNAL OF CLINICAL INVESTIGATION

Association of autoantibody specificity and response to intravenous immunoglobulin G therapy in immune thrombocytopenia: a multicenter cohort study

(2014) J. Peng et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The Ashwell-Morell receptor regulates hepatic thrombopoietin production via JAK2-STAT3 signaling

(2014) Renata Grozovsky et al.   NATURE MEDICINE

Successful treatment with oseltamivir phosphate in a patient with chronic immune thrombocytopenia positive for anti-GPIb/IX autoantibody

(2014) Linlin Shao et al.   PLATELETS

The functional role of platelets in the regulation of angiogenesis

(2014) Tony G. Walsh et al.   PLATELETS

Pathogenesis of immune thrombocytopenia

(2014) Douglas B. Cines et al.   PRESSE MEDICALE

Platelets guide the formation of early metastatic niches

(2014) M. Labelle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Platelets, Selectins, and the Control of Tumor Metastasis

(2014) Lucy A. Coupland et al.   SEMINARS IN ONCOLOGY

Platelet–Cancer Interactions

(2014) Julie Stakiw et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Platelet Membrane Glycoproteins: A Historical Review

(2014) Alan Nurden   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Plant food anthocyanins inhibit platelet granule secretion in hypercholesterolaemia: Involving the signalling pathway of PI3K–Akt

(2014) Fenglin Song et al.   THROMBOSIS AND HAEMOSTASIS

Phosphatidylserine exposure, microparticle formation and mitochondrial depolarisation in Glanzmann thrombasthenia platelets

(2014) Hong Wang et al.   THROMBOSIS AND HAEMOSTASIS

Fibrinogen and red blood cells in venous thrombosis

(2014) Maria M. Aleman et al.   THROMBOSIS RESEARCH

The fibrinogen but not the Factor VIII content of transfused plasma determines its effectiveness at reducing bleeding in coagulopathic mice

(2014) Louise J. Eltringham-Smith et al.   TRANSFUSION

Platelets Mediate Oxidized Low-Density Lipoprotein–Induced Monocyte Extravasation and Foam Cell Formation

(2013) Sigrun Badrnya et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Immunoreceptor Tyrosine-Based Inhibitory Motif (ITIM)-Mediated Inhibitory Signaling Is Regulated by Sequential Phosphorylation Mediated by Distinct Nonreceptor Tyrosine Kinases: A Case Study Involving PECAM-1

(2013) Benjamin E. Tourdot et al.   BIOCHEMISTRY

VWF-mediated leukocyte recruitment with chromatin decondensation by PAD4 increases myocardial ischemia/reperfusion injury in mice

(2013) A. S. Savchenko et al.   BLOOD

Thrombosis: tangled up in NETs

(2013) K. Martinod et al.   BLOOD

Hydrogen Peroxide Promotes Aging-Related Platelet Hyperactivation and Thrombosis

(2013) Sanjana Dayal et al.   CIRCULATION

The biology of thrombopoietin and thrombopoietin receptor agonists

(2013) David J. Kuter   INTERNATIONAL JOURNAL OF HEMATOLOGY

The incredible journey: From megakaryocyte development to platelet formation

(2013) Kellie R. Machlus et al.   JOURNAL OF CELL BIOLOGY

Platelets mediate lymphovenous hemostasis to maintain blood-lymphatic separation throughout life

(2013) Paul R. Hess et al.   JOURNAL OF CLINICAL INVESTIGATION

Glycoprotein Ibα and FcγRIIa play key roles in platelet activation by the colonizing bacterium,Streptococcus oralis

(2013) D. O. Tilley et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The organizing principle of the platelet glycoprotein Ib-IX-V complex

(2013) R. Li et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Analysis of inter-subunit contacts reveals the structural malleability of extracellular domains in platelet glycoprotein Ib-IX complex

(2013) L. Zhou et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2

(2013) Brett H. Herzog et al.   NATURE

Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis

(2013) Andrew J Murphy et al.   NATURE MEDICINE

Immune Dysregulation in Immune Thrombocytopenia

(2013) Karina Yazdanbakhsh et al.   SEMINARS IN HEMATOLOGY

Co-stimulation with LPS or Poly I:C markedly enhances the anti-platelet immune response and severity of fetal and neonatal alloimmune thrombocytopenia

(2013) Conglei Li et al.   THROMBOSIS AND HAEMOSTASIS

The physiological and pathophysiological roles of platelet CLEC-2

(2013) Stacey A. Langan et al.   THROMBOSIS AND HAEMOSTASIS

Anfibatide, a novel GPIb complex antagonist, inhibits platelet adhesion and thrombus formation in vitro and in vivo in murine models of thrombosis

(2013) Yan Hou et al.   THROMBOSIS AND HAEMOSTASIS

Microvesicles as risk markers for venous thrombosis

(2013) Pierre-Emmanuel Rautou et al.   Expert Review of Hematology

Neutrophil Extracellular Trap (NET) Impact on Deep Vein Thrombosis

(2012) Tobias A. Fuchs et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cadherin 6 Has a Functional Role in Platelet Aggregation and Thrombus Formation

(2012) Eimear Dunne et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Thymic retention of CD4+CD25+FoxP3+ T regulatory cells is associated with their peripheral deficiency and thrombocytopenia in a murine model of immune thrombocytopenia

(2012) R. Aslam et al.   BLOOD

The platelet "sugar high" in diabetes

(2012) H. Ni   BLOOD

Polyphosphate: an ancient molecule that links platelets, coagulation, and inflammation

(2012) J. H. Morrissey et al.   BLOOD

Platelet secretion is kinetically heterogeneous in an agonist-responsive manner

(2012) D. Jonnalagadda et al.   BLOOD

The Cell Motility Modulator Slit2 Is a Potent Inhibitor of Platelet Function

(2012) Sajedabanu Patel et al.   CIRCULATION

Platelet-Derived Chemokines in Atherogenesis: What’s New?

(2012) Christian A. Gleissner   Current Vascular Pharmacology

Platelet Activation Receptor CLEC-2 Regulates Blood/Lymphatic Vessel Separation by Inhibiting Proliferation, Migration, and Tube Formation of Lymphatic Endothelial Cells

(2012) Makoto Osada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo

(2012) Marie-Luise von Brühl et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Predominant autoantibody response to GPIb/IX in a regulatory T-cell-deficient mouse model for immune thrombocytopenia

(2012) T. NISHIMOTO et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Plant Food Delphinidin-3-Glucoside Significantly Inhibits Platelet Activation and Thrombosis: Novel Protective Roles against Cardiovascular Diseases

(2012) Yan Yang et al.   PLoS One

Platelet Factor 4 and Duffy Antigen Required for Platelet Killing of Plasmodium falciparum

(2012) B. J. McMorran et al.   SCIENCE

Platelet-leukocyte crosstalk: Linking proinflammatory responses to procoagulant state

(2012) Mehran Ghasemzadeh et al.   THROMBOSIS RESEARCH

Toward a prophylaxis against fetal and neonatal alloimmune thrombocytopenia: induction of antibody-mediated immune suppression and prevention of severe clinical complications in a murine model

(2012) Heidi Tiller et al.   TRANSFUSION

The Initial Hours of Metastasis: The Importance of Cooperative Host-Tumor Cell Interactions during Hematogenous Dissemination

(2012) M. Labelle et al.   Cancer Discovery

The wolf in sheep’s clothing

(2012) Theresa Placke et al.   OncoImmunology

Platelet antibodies and fetal growth: maternal antibodies against fetal platelet antigen 1a are strongly associated with reduced birthweight in boys

(2011) HEIDI TILLER et al.   ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA

Relative efficacy of steroid therapy in immune thrombocytopenia mediated by anti-platelet GPIIbIIIa versus GPIbα antibodies

(2011) Qingshu Zeng et al.   AMERICAN JOURNAL OF HEMATOLOGY

Platelet Administration Via the Portal Vein Promotes Liver Regeneration in Rats After 70% Hepatectomy

(2011) Ryota Matsuo et al.   ANNALS OF SURGERY

The angiogenic process as a therapeutic target in cancer

(2011) Esther M. Bridges et al.   BIOCHEMICAL PHARMACOLOGY

Quantitative immunofluorescence mapping reveals little functional coclustering of proteins within platelet  -granules

(2011) J. Kamykowski et al.   BLOOD

Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4

(2011) F. Semeraro et al.   BLOOD

CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development

(2011) B. A. Finney et al.   BLOOD

Long-term clinical outcomes of patients with primary chronic immune thrombocytopenia: a Danish population-based cohort study

(2011) M. Norgaard et al.   BLOOD

Release of angiogenesis regulatory proteins from platelet alpha granules: modulation of physiologic and pathologic angiogenesis

(2011) E. M. Battinelli et al.   BLOOD

Histones induce rapid and profound thrombocytopenia in mice

(2011) T. A. Fuchs et al.   BLOOD

Distinct platelet packaging, release, and surface expression of proangiogenic and antiangiogenic factors on different platelet stimuli

(2011) M. Chatterjee et al.   BLOOD

Apoptosis in the anucleate platelet

(2011) Valery Leytin   BLOOD REVIEWS

Direct Signaling between Platelets and Cancer Cells Induces an Epithelial-Mesenchymal-Like Transition and Promotes Metastasis

(2011) Myriam Labelle et al.   CANCER CELL

Platelet-Derived MHC Class I Confers a Pseudonormal Phenotype to Cancer Cells That Subverts the Antitumor Reactivity of Natural Killer Immune Cells

(2011) T. Placke et al.   CANCER RESEARCH

Novel Antiplatelet Drug Revacept (Dimeric Glycoprotein VI-Fc) Specifically and Efficiently Inhibited Collagen-Induced Platelet Aggregation Without Affecting General Hemostasis in Humans

(2011) Martin Ungerer et al.   CIRCULATION

Anthocyanin Extract from Black Rice Significantly Ameliorates Platelet Hyperactivity and Hypertriglyceridemia in Dyslipidemic Rats Induced by High Fat Diets

(2011) Yan Yang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The maternal immune response to fetal platelet GPIbα causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies

(2011) Conglei Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Neutrophil extracellular traps promote deep vein thrombosis in mice

(2011) A. BRILL et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

(2011) Bin-Zhi Qian et al.   NATURE

Mutations in NBEAL2, encoding a BEACH protein, cause gray platelet syndrome

(2011) Walter HA Kahr et al.   NATURE GENETICS

Platelet-leukocyte interactions in thrombosis

(2011) Chiara Cerletti et al.   THROMBOSIS RESEARCH

Extracellular Matrix Proteins in Hemostasis and Thrombosis

(2011) W. Bergmeier et al.   Cold Spring Harbor Perspectives in Biology

The filamins

(2011) Fumihiko Nakamura et al.   Cell Adhesion & Migration

Novel Anti-bacterial Activities of β-defensin 1 in Human Platelets: Suppression of Pathogen Growth and Signaling of Neutrophil Extracellular Trap Formation

(2011) Bjoern F. Kraemer et al.   PLoS Pathogens

Deciphering the human platelet sheddome

(2010) K. P. Fong et al.   BLOOD

Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation

(2010) P. Uhrin et al.   BLOOD

Platelet-derived thrombospondin-1 is a critical negative regulator and potential biomarker of angiogenesis

(2010) A. Zaslavsky et al.   BLOOD

Animal model of fetal and neonatal immune thrombocytopenia: role of neonatal Fc receptor in the pathogenesis and therapy

(2010) P. Chen et al.   BLOOD

von Willebrand factor-mediated platelet adhesion is critical for deep vein thrombosis in mouse models

(2010) A. Brill et al.   BLOOD

Anucleate platelets generate progeny

(2010) H. Schwertz et al.   BLOOD

The platelet interior revisited: electron tomography reveals tubular  -granule subtypes

(2010) H. van Nispen tot Pannerden et al.   BLOOD

Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling

(2010) C. C. Bertozzi et al.   BLOOD

Platelets Play an Essential Role in Separating the Blood and Lymphatic Vasculatures During Embryonic Angiogenesis

(2010) Laura Carramolino et al.   CIRCULATION RESEARCH

Infusion of mature megakaryocytes into mice yields functional platelets

(2010) Rudy Fuentes et al.   JOURNAL OF CLINICAL INVESTIGATION

Factors Affecting Wound Healing

(2010) S. Guo et al.   JOURNAL OF DENTAL RESEARCH

PECAM-1 functions as a negative regulator of laminin-induced platelet activation

(2010) J. CROCKETT et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Calcium-dependent phospholipid scrambling by TMEM16F

(2010) Jun Suzuki et al.   NATURE

Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases

(2010) Steffen Massberg et al.   NATURE MEDICINE

Protein expression in platelets from six species that differ in their open canalicular system

(2010) Wangsun Choi et al.   PLATELETS

Extracellular DNA traps promote thrombosis

(2010) T. A. Fuchs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of von Willebrand factor by ARC1779 in patients with acute thrombotic thrombocytopenic purpura

(2010) Bernd Jilma et al.   THROMBOSIS AND HAEMOSTASIS

Mice with deleted multimerin 1 and α-synuclein genes have impaired platelet adhesion and impaired thrombus formation that is corrected by multimerin 1

(2010) Adili Reheman et al.   THROMBOSIS RESEARCH

Snaclecs (snake C-type lectins) that inhibit or activate platelets by binding to receptors

(2010) Kenneth J. Clemetson   TOXICON

A murine model of severe immune thrombocytopenia is induced by antibody- and CD8+ T cell-mediated responses that are differentially sensitive to therapy

(2009) L. Chow et al.   BLOOD

Neutrophils phagocytose activated platelets in vivo: a phosphatidylserine, P-selectin, and  2 integrin-dependent cell clearance program

(2009) N. Maugeri et al.   BLOOD

Distinct spatio-temporal Ca2+ signaling elicited by integrin  2 1 and glycoprotein VI under flow

(2009) M. Mazzucato et al.   BLOOD

Fibrinogen is required for maintenance of platelet intracellular and cell-surface P-selectin expression

(2009) H. Yang et al.   BLOOD

Fibrinogen selects selectins

(2009) H. Schwertz et al.   BLOOD

Selectin-mediated activation of endothelial cells induces expression of CCL5 and promotes metastasis through recruitment of monocytes

(2009) H. Laubli et al.   BLOOD

Platelet α-granules: Basic biology and clinical correlates

(2009) Price Blair et al.   BLOOD REVIEWS

Platelet-Derived Transforming Growth Factor-  Down-Regulates NKG2D Thereby Inhibiting Natural Killer Cell Antitumor Reactivity

(2009) H.-G. Kopp et al.   CANCER RESEARCH

Platelet Polyphosphates Are Proinflammatory and Procoagulant Mediators In Vivo

(2009) Felicitas Müller et al.   CELL

Antiplatelet Antibodies in Chronic Immune Thrombocytopenia and Their Role in Platelet Destruction and Defective Platelet Production

(2009) Robert McMillan   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Lipopolysaccharide Stimulates Platelet Secretion and Potentiates Platelet Aggregation via TLR4/MyD88 and the cGMP-Dependent Protein Kinase Pathway

(2009) G. Zhang et al.   JOURNAL OF IMMUNOLOGY

Abnormal hemostasis in a knock-in mouse carrying a variant of factor IX with impaired binding to collagen type IV

(2009) T. GUI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Diagnosis and management of the fetus and neonate with alloimmune thrombocytopenia

(2009) J. BUSSEL   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Dynamics of platelet thrombus formation

(2009) S. P. JACKSON et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Protein synthesis by platelets: historical and new perspectives

(2009) A. S. WEYRICH et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Safety and tolerability of SCH 530348 in patients undergoing non-urgent percutaneous coronary intervention: a randomised, double-blind, placebo-controlled phase II study

(2009) Richard C Becker et al.   LANCET

Dual roles for hepatic lectin receptors in the clearance of chilled platelets

(2009) Viktoria Rumjantseva et al.   NATURE MEDICINE

Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice

(2009) Rory R Koenen et al.   NATURE MEDICINE

Fetal/Neonatal Allo-Immune Thrombocytopenia (FNAIT): Past, Present, and Future

(2009) V M. L. Serrarens-Janssen et al.   OBSTETRICAL & GYNECOLOGICAL SURVEY

Platelets Kill Intraerythrocytic Malarial Parasites and Mediate Survival to Infection

(2009) B. J. McMorran et al.   SCIENCE

Cell Adhesion Mechanisms in Platelets

(2008) David Varga-Szabo et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Platelet Chemokines in Vascular Disease

(2008) Christian A. Gleissner et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Signal-Dependent Protein Synthesis by Activated Platelets

(2008) Guy A. Zimmerman et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Plasma fibronectin depletion enhances platelet aggregation and thrombus formation in mice lacking fibrinogen and von Willebrand factor

(2008) A. Reheman et al.   BLOOD

CEACAM1 negatively regulates platelet-collagen interactions and thrombus growth in vitro and in vivo

(2008) C. Wong et al.   BLOOD

In vitro and in vivo evidence for shear-induced activation of latent transforming growth factor- 1

(2008) J. Ahamed et al.   BLOOD

Platelet lipoprotein interplay: trigger of foam cell formation and driver of atherosclerosis

(2008) D. Siegel-Axel et al.   CARDIOVASCULAR RESEARCH

The platelet release reaction: just when you thought platelet secretion was simple

(2008) Qiansheng Ren et al.   CURRENT OPINION IN HEMATOLOGY

Triggers, targets and treatments for thrombosis

(2008) Nigel Mackman   NATURE

A new player in lymphocyte homing

(2008) Dietmar Vestweber et al.   NATURE IMMUNOLOGY

The Ashwell receptor mitigates the lethal coagulopathy of sepsis

(2008) Prabhjit K Grewal et al.   NATURE MEDICINE

Mechanisms of Thrombus Formation

(2008) Bruce Furie et al.   NEW ENGLAND JOURNAL OF MEDICINE