Molecularly Distinct NLRP3 Inducers Mediate Diverse Ratios of Interleukin-1β and Interleukin-18 from Human Monocytes

Repeated vs. Acute Exposure of RAW264.7 Mouse Macrophages to Silica Nanoparticles: A Bioaccumulation and Functional Change Study

(2020) Anaëlle Torres et al.   Nanomaterials

Interleukin-18 in Health and Disease

(2019) Koubun Yasuda et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Inflammatory and coagulatory markers and exposure to different size fractions of particle mass, number and surface area air concentrations in Swedish iron foundries, in particular respirable quartz

(2019) Håkan Westberg et al.   INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH

Inflammasomes in the pathophysiology of autoinflammatory syndromes

(2019) Sarang Tartey et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Respiratory health and inflammatory markers - Exposure to respirable dust and quartz and chemical binders in Swedish iron foundries

(2019) Lena Andersson et al.   PLoS One

Recent advances in inflammasome biology

(2018) David E Place et al.   CURRENT OPINION IN IMMUNOLOGY

How Inflammasomes Inform Adaptive Immunity

(2018) Charles L. Evavold et al.   JOURNAL OF MOLECULAR BIOLOGY

Unique Action of Interleukin-18 on T Cells and Other Immune Cells

(2018) Kenji Nakanishi   Frontiers in Immunology

On demand use of anakinra for attacks of familial Mediterranean fever (FMF)

(2018) Hakan Babaoglu et al.   CLINICAL RHEUMATOLOGY

BCAP links IL-1R to the PI3K–mTOR pathway and regulates pathogenic Th17 cell differentiation

(2018) Krystin Deason et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Critical Role of the IL-1β-IL-1R Signaling Pathway in Skin Inflammation and Psoriasis Pathogenesis

(2018) Yihua Cai et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Anakinra Therapy for Non-cancer Inflammatory Diseases

(2018) Giulio Cavalli et al.   Frontiers in Pharmacology

Overview of the IL-1 family in innate inflammation and acquired immunity

(2017) Charles A. Dinarello   IMMUNOLOGICAL REVIEWS

Silica nanoparticles induce NLRP3 inflammasome activation in human primary immune cells

(2017) Diana M Gómez et al.   Innate Immunity

Mechanisms governing inflammasome activation, assembly and pyroptosis induction

(2017) Sannula Kesavardhana et al.   INTERNATIONAL IMMUNOLOGY

Chitin and chitinase: Role in pathogenicity, allergenicity and health

(2017) Seema Patel et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Cutting Edge: Distinct Regulatory Mechanisms Control Proinflammatory Cytokines IL-18 and IL-1β

(2017) Qifan Zhu et al.   JOURNAL OF IMMUNOLOGY

SR-B1 Is a Silica Receptor that Mediates Canonical Inflammasome Activation

(2017) Misato Tsugita et al.   Cell Reports

Autoinflammatory Diseases with Periodic Fevers

(2017) Erdal Sag et al.   Current Rheumatology Reports

Potential of IL-1, IL-18 and Inflammasome Inhibition for the Treatment of Inflammatory Skin Diseases

(2017) Gabriele Fenini et al.   Frontiers in Pharmacology

Airway gene expression of IL-1 pathway mediators predicts exacerbation risk in obstructive airway disease

(2017) Katherine Baines et al.   International Journal of Chronic Obstructive Pulmonary Disease

Sterile signals generate weaker and delayed macrophage NLRP3 inflammasome responses relative to microbial signals

(2016) Jelena S Bezbradica et al.   Cellular & Molecular Immunology

Human Monocytes Engage an Alternative Inflammasome Pathway

(2016) Moritz M. Gaidt et al.   IMMUNITY

Expression of IL-1β in rhesus EAE and MS lesions is mainly induced in the CNS itself

(2016) Saskia Maria Burm et al.   Journal of Neuroinflammation

Mechanism and Regulation of NLRP3 Inflammasome Activation

(2016) Yuan He et al.   TRENDS IN BIOCHEMICAL SCIENCES

ASC filament formation serves as a signal amplification mechanism for inflammasomes

(2016) Mathias S. Dick et al.   Nature Communications

Treating Pulmonary Silicosis by Blocking Interleukin 1

(2015) Giulio Cavalli et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Autoimmunity and autoinflammation as the yin and yang of idiopathic recurrent acute pericarditis

(2015) Luca Cantarini et al.   AUTOIMMUNITY REVIEWS

The interleukin (IL)-1 cytokine family – Balance between agonists and antagonists in inflammatory diseases

(2015) Jennifer Palomo et al.   CYTOKINE

Spectrum and Mechanisms of Inflammasome Activation by Chitosan

(2014) C. L. Bueter et al.   JOURNAL OF IMMUNOLOGY

Effect of Silica Particle Size on Macrophage Inflammatory Responses

(2014) Toshimasa Kusaka et al.   PLoS One

Association between the IL1B, IL1RN polymorphisms and COPD risk: A meta-analysis

(2014) Zi-Kang Xie et al.   Scientific Reports

K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter

(2013) Raúl Muñoz-Planillo et al.   IMMUNITY

Divergence of IL-1, IL-18, and cell death in NLRP3 inflammasomopathies

(2013) Susannah D. Brydges et al.   JOURNAL OF CLINICAL INVESTIGATION

Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β

(2012) Christina E. Zielinski et al.   NATURE

Distinct Licensing of IL-18 and IL-1β Secretion in Response to NLRP3 Inflammasome Activation

(2012) Rebecca L. Schmidt et al.   PLoS One

Interleukin-1 in the pathogenesis and treatment of inflammatory diseases

(2011) C. A. Dinarello   BLOOD

Chitosan but Not Chitin Activates the Inflammasome by a Mechanism Dependent upon Phagocytosis

(2011) Chelsea L. Bueter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interleukin (IL) 1β Induction of IL-6 Is Mediated by a Novel Phosphatidylinositol 3-Kinase-dependent AKT/IκB Kinase α Pathway Targeting Activator Protein-1

(2008) Catherine M. Cahill et al.   JOURNAL OF BIOLOGICAL CHEMISTRY