Klotho overexpression improves amyloid‐β clearance and cognition in the APP/PS1 mouse model of Alzheimer's disease
出版年份 2020 全文链接
标题
Klotho overexpression improves amyloid‐β clearance and cognition in the APP/PS1 mouse model of Alzheimer's disease
作者
关键词
-
出版物
AGING CELL
Volume 19, Issue 10, Pages -
出版商
Wiley
发表日期
2020-09-21
DOI
10.1111/acel.13239
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Targeting amyloid clearance in Alzheimer's disease as a therapeutic strategy
- (2019) Natalia N. Nalivaeva et al. BRITISH JOURNAL OF PHARMACOLOGY
- Enhanced Expression of Secreted α-Klotho in the Hippocampus Alters Nesting Behavior and Memory Formation in Mice
- (2019) Dongxue Li et al. Frontiers in Cellular Neuroscience
- Klotho Is Neuroprotective in the Superoxide Dismutase (SOD1G93A) Mouse Model of ALS
- (2019) Ella Zeldich et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Lentiviral vector–mediated overexpression of Klotho in the brain improves Alzheimer's disease–like pathology and cognitive deficits in mice
- (2019) Chen-Ye Zeng et al. NEUROBIOLOGY OF AGING
- Folate receptor alpha-modified nanoparticles for the targeting of the central nervous system
- (2019) Nataliya Kuplennik et al. ACS Applied Materials & Interfaces
- NLRP3 inflammasome activation drives tau pathology
- (2019) Christina Ising et al. NATURE
- Cerebral amyloid angiopathy and Alzheimer disease — one peptide, two pathways
- (2019) Steven M. Greenberg et al. Nature Reviews Neurology
- Transplantation of in vitro cultured endothelial progenitor cells repairs the blood-brain barrier and improves cognitive function of APP/PS1 transgenic AD mice
- (2018) Shishuang Zhang et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Magnesium Reduces Blood-Brain Barrier Permeability and Regulates Amyloid-β Transcytosis
- (2018) Donghui Zhu et al. MOLECULAR NEUROBIOLOGY
- Characterization of Impaired Cerebrovascular Structure in APP/PS1 Mouse Brains
- (2018) Kee-Chan Ahn et al. NEUROSCIENCE
- Clearance of Amyloid Beta and Tau in Alzheimer’s Disease: from Mechanisms to Therapy
- (2018) Shu-Hui Xin et al. NEUROTOXICITY RESEARCH
- Klotho controls the brain–immune system interface in the choroid plexus
- (2018) Lei Zhu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The anti-aging protein klotho alleviates injury of nigrostriatal dopaminergic pathway in 6-hydroxydopamine rat model of Parkinson's disease: Involvement of PKA/CaMKII/CREB signaling
- (2017) Tourandokht Baluchnejadmojarad et al. EXPERIMENTAL GERONTOLOGY
- NLRP3 Inflammasome Inhibitor Ameliorates Amyloid Pathology in a Mouse Model of Alzheimer’s Disease
- (2017) Jun Yin et al. MOLECULAR NEUROBIOLOGY
- A systemic view of Alzheimer disease — insights from amyloid-β metabolism beyond the brain
- (2017) Jun Wang et al. Nature Reviews Neurology
- Neuroprotective Effect of Ligustilide through Induction of α-Secretase Processing of Both APP and Klotho in a Mouse Model of Alzheimer’s Disease
- (2017) Xi Kuang et al. Frontiers in Aging Neuroscience
- The amyloid hypothesis of Alzheimer's disease at 25 years
- (2016) Dennis J Selkoe et al. EMBO Molecular Medicine
- The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer’s disease
- (2016) Marina Saresella et al. Molecular Neurodegeneration
- 1,25-Dihydroxyvitamin D3 regulates expression of LRP1 and RAGE in vitro and in vivo, enhancing Aβ1–40 brain-to-blood efflux and peripheral uptake transport
- (2016) Y.-X. Guo et al. NEUROSCIENCE
- Role of RAGE in Alzheimer’s Disease
- (2015) Zhiyou Cai et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Molecular Basis of Klotho: From Gene to Function in Aging
- (2015) Yuechi Xu et al. ENDOCRINE REVIEWS
- α-Klotho Expression in Human Tissues
- (2015) Kenneth Lim et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Life Extension Factor Klotho Prevents Mortality and Enhances Cognition in hAPP Transgenic Mice
- (2015) D. B. Dubal et al. JOURNAL OF NEUROSCIENCE
- P-glycoprotein expression and amyloid accumulation in human aging and Alzheimer's disease: preliminary observations
- (2015) Catherine Chiu et al. NEUROBIOLOGY OF AGING
- Secreted and Transmembrane αKlotho Isoforms Have Different Spatio-Temporal Profiles in the Brain during Aging and Alzheimer's Disease Progression
- (2015) Anna Massó et al. PLoS One
- Alzheimer's disease
- (2015) Colin L. Masters et al. Nature Reviews Disease Primers
- Life Extension Factor Klotho Enhances Cognition
- (2014) Dena B. Dubal et al. Cell Reports
- Targeting ApoE4/ApoE receptor LRP1 in Alzheimer's disease
- (2013) Henna Martiskainen et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Blood–Brain Barrier Dysfunction as a Cause and Consequence of Alzheimer's Disease
- (2013) Michelle A Erickson et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation
- (2013) Frederick J Sheedy et al. NATURE IMMUNOLOGY
- Klotho in the cerebrospinal fluid of adults with and without Alzheimer's disease
- (2013) Richard D. Semba et al. NEUROSCIENCE LETTERS
- The role of ABCB1 and ABCA1 in beta-amyloid clearance at the neurovascular unit in Alzheimer's disease
- (2013) Ayman ElAli et al. Frontiers in Physiology
- NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
- (2012) Michael T. Heneka et al. NATURE
- Reduced CSF turnover and decreased ventricular Aβ42 levels are related
- (2011) Jean-Marie Serot et al. BMC NEUROSCIENCE
- Differential effects of dietary fatty acids on the cerebral distribution of plasma-derived apo B lipoproteins with amyloid-β
- (2009) Ryusuke Takechi et al. BRITISH JOURNAL OF NUTRITION
- Amyloid Deposition and Influx Transporter Expression at the Blood-Brain Barrier Increase in Normal Aging
- (2009) Gerald D. Silverberg et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started