标题
Klotho controls the brain–immune system interface in the choroid plexus
作者
关键词
-
出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 115, Issue 48, Pages E11388-E11396
出版商
Proceedings of the National Academy of Sciences
发表日期
2018-11-10
DOI
10.1073/pnas.1808609115
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Soluble klotho binds monosialoganglioside to regulate membrane microdomains and growth factor signaling
- (2017) George Dalton et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inflammaging and ‘Garb-aging’
- (2017) Claudio Franceschi et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Vitamin D both facilitates and attenuates the cellular response to lipopolysaccharide
- (2017) Ling Chen et al. Scientific Reports
- Regulation of cerebrospinal fluid (CSF) flow in neurodegenerative, neurovascular and neuroinflammatory disease
- (2016) Matthew J. Simon et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Expression of A152T human tau causes age‐dependent neuronal dysfunction and loss in transgenic mice
- (2016) Sumihiro Maeda et al. EMBO REPORTS
- The in vivo effects of a fraction from Dioscorea spongiosa on glucocorticoid-induced osteoporosis
- (2016) Na Han et al. JOURNAL OF ETHNOPHARMACOLOGY
- The Choroid Plexus in Healthy and Diseased Brain
- (2016) Charanjit Kaur et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Origin, fate and dynamics of macrophages at central nervous system interfaces
- (2016) Tobias Goldmann et al. NATURE IMMUNOLOGY
- New tools for studying microglia in the mouse and human CNS
- (2016) Mariko L. Bennett et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Type I/II Interferon Balance in the Regulation of Brain Physiology and Pathology
- (2016) Aleksandra Deczkowska et al. TRENDS IN IMMUNOLOGY
- The choroid plexus transcriptome reveals changes in type I and II interferon responses in a mouse model of Alzheimer’s disease
- (2015) Sandro Dá Mesquita et al. BRAIN BEHAVIOR AND IMMUNITY
- Molecular Basis of Klotho: From Gene to Function in Aging
- (2015) Yuechi Xu et al. ENDOCRINE REVIEWS
- Spatially Heterogeneous Choroid Plexus Transcriptomes Encode Positional Identity and Contribute to Regional CSF Production
- (2015) M. P. Lun et al. JOURNAL OF NEUROSCIENCE
- Neuroinflammation in Alzheimer's disease
- (2015) Michael T Heneka et al. LANCET NEUROLOGY
- Immune dysregulation and cognitive vulnerability in the aging brain: Interactions of microglia, IL-1β, BDNF and synaptic plasticity
- (2015) Susan L. Patterson NEUROPHARMACOLOGY
- Secreted and Transmembrane αKlotho Isoforms Have Different Spatio-Temporal Profiles in the Brain during Aging and Alzheimer's Disease Progression
- (2015) Anna Massó et al. PLoS One
- Neurocognitive Aging and the Hippocampus across Species
- (2015) Stephanie L. Leal et al. TRENDS IN NEUROSCIENCES
- NLRP3 inflammasome: From a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases
- (2015) Amna Abderrazak et al. Redox Biology
- BioAge: Toward a multi-determined, mechanistic account of cognitive aging
- (2014) Correne A. DeCarlo et al. AGEING RESEARCH REVIEWS
- Identification of Cleavage Sites Leading to the Shed Form of the Anti-Aging Protein Klotho
- (2014) Ci-Di Chen et al. BIOCHEMISTRY
- Expression of Nampt in Hippocampal and Cortical Excitatory Neurons Is Critical for Cognitive Function
- (2014) L. R. Stein et al. JOURNAL OF NEUROSCIENCE
- The Kidney Is the Principal Organ Mediating Klotho Effects
- (2014) K. Lindberg et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Klotho Gene Deficiency Causes Salt-Sensitive Hypertension via Monocyte Chemotactic Protein-1/CC Chemokine Receptor 2-Mediated Inflammation
- (2014) X. Zhou et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Microglial priming in neurodegenerative disease
- (2014) V. Hugh Perry et al. Nature Reviews Neurology
- Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease
- (2014) Marco Prinz et al. NATURE REVIEWS NEUROSCIENCE
- Aging-induced type I interferon response at the choroid plexus negatively affects brain function
- (2014) K. Baruch et al. SCIENCE
- Thioredoxin/Txnip: Redoxisome, as a Redox Switch for the Pathogenesis of Diseases
- (2014) Eiji Yoshihara et al. Frontiers in Immunology
- IFN-γ-dependent activation of the brain’s choroid plexus for CNS immune surveillance and repair
- (2013) Gilad Kunis et al. BRAIN
- CNS-specific T cells shape brain function via the choroid plexus
- (2013) Kuti Baruch et al. BRAIN BEHAVIOR AND IMMUNITY
- Expression of klotho mRNA and protein in rat brain parenchyma from early postnatal development into adulthood
- (2013) Sarah M. Clinton et al. BRAIN RESEARCH
- Canonical Nlrp3 Inflammasome Links Systemic Low-Grade Inflammation to Functional Decline in Aging
- (2013) Yun-Hee Youm et al. Cell Metabolism
- Impact of aging brain circuits on cognition
- (2013) Rachel D. Samson et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Interferons in the central nervous system: A few instruments play many tunes
- (2013) Trevor Owens et al. GLIA
- Microglial Activation Milieu Controls Regulatory T Cell Responses
- (2013) F. Ebner et al. JOURNAL OF IMMUNOLOGY
- A Dramatic Increase of C1q Protein in the CNS during Normal Aging
- (2013) A. H. Stephan et al. JOURNAL OF NEUROSCIENCE
- Klotho in the cerebrospinal fluid of adults with and without Alzheimer's disease
- (2013) Richard D. Semba et al. NEUROSCIENCE LETTERS
- CNS-specific immunity at the choroid plexus shifts toward destructive Th2 inflammation in brain aging
- (2013) K. Baruch et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Type I IFN Triggers RIG-I/TLR3/NLRP3-dependent Inflammasome Activation in Influenza A Virus Infected Cells
- (2013) Julien Pothlichet et al. PLoS Pathogens
- Bone Marrow-derived Macrophage Production
- (2013) Virginie Trouplin et al. Jove-Journal of Visualized Experiments
- Thioredoxin-Interacting Protein Mediates ER Stress-Induced β Cell Death through Initiation of the Inflammasome
- (2012) Christine M. Oslowski et al. Cell Metabolism
- The secreted Klotho protein restores phosphate retention and suppresses accelerated aging in Klotho mutant mice
- (2012) Tso-Hsiao Chen et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- The immunology of neurodegeneration
- (2012) Eva Czirr et al. JOURNAL OF CLINICAL INVESTIGATION
- Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study
- (2012) David H Cribbs et al. Journal of Neuroinflammation
- Targeted Deletion of Klotho in Kidney Distal Tubule Disrupts Mineral Metabolism
- (2012) H. Olauson et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
- (2012) Michael T. Heneka et al. NATURE
- Nuclear localization of Klotho in brain: an anti-aging protein
- (2012) Dwight C. German et al. NEUROBIOLOGY OF AGING
- Human P301L-Mutant Tau Expression in Mouse Entorhinal-Hippocampal Network Causes Tau Aggregation and Presynaptic Pathology but No Cognitive Deficits
- (2012) Julie A. Harris et al. PLoS One
- A molecular characterization of the choroid plexus and stress-induced gene regulation
- (2012) M Sathyanesan et al. Translational Psychiatry
- Thioredoxin Interacting Protein: Redox Dependent and Independent Regulatory Mechanisms
- (2011) Oded N. Spindel et al. ANTIOXIDANTS & REDOX SIGNALING
- IRF7: activation, regulation, modification and function
- (2011) S Ning et al. GENES AND IMMUNITY
- Ablation of Cellular Prion Protein Does Not Ameliorate Abnormal Neural Network Activity or Cognitive Dysfunction in the J20 Line of Human Amyloid Precursor Protein Transgenic Mice
- (2011) M. Cisse et al. JOURNAL OF NEUROSCIENCE
- Non-canonical inflammasome activation targets caspase-11
- (2011) Nobuhiko Kayagaki et al. NATURE
- Klotho suppresses RIG-I-mediated senescence-associated inflammation
- (2011) Feng Liu et al. NATURE CELL BIOLOGY
- The Inflammasomes: Guardians of the Body
- (2009) Fabio Martinon et al. Annual Review of Immunology
- Thioredoxin interacting protein (TXNIP) induces inflammation through chromatin modification in retinal capillary endothelial cells under diabetic conditions
- (2009) Lorena Perrone et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Thioredoxin-interacting protein links oxidative stress to inflammasome activation
- (2009) Rongbin Zhou et al. NATURE IMMUNOLOGY
- Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1β and anti-inflammatory IL-10 cytokines
- (2008) Christopher J. Henry et al. BRAIN BEHAVIOR AND IMMUNITY
- Morphological and biochemical signs of age-related neurodegenerative changes in klotho mutant mice
- (2008) M. Shiozaki et al. NEUROSCIENCE
- IL-1 is an essential mediator of the antineurogenic and anhedonic effects of stress
- (2008) J. W. Koo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gene profile analysis implicates Klotho as an important contributor to aging changes in brain white matter of the rhesus monkey
- (2007) James A. Duce et al. GLIA
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