Nuclear Regulation of Wnt/β-Catenin Signaling: It’s a Complex Situation

Tubular β-catenin and FoxO3 interactions protect in chronic kidney disease

(2020) Stellor Nlandu-Khodo et al.   JCI Insight

Repression of MAP3K1 expression and JNK activity by canonical Wnt signaling

(2018) Qinghang Meng et al.   DEVELOPMENTAL BIOLOGY

RAPGEF5 Regulates Nuclear Translocation of β-Catenin

(2018) John N. Griffin et al.   DEVELOPMENTAL CELL

Phosphorylation of XIAP at threonine 180 controls its activity in Wnt signaling

(2018) Victoria H. Ng et al.   JOURNAL OF CELL SCIENCE

Mutations in Bcl9 and Pygo genes cause congenital heart defects by tissue-specific perturbation of Wnt/β-catenin signaling

(2018) Claudio Cantù et al.   GENES & DEVELOPMENT

Kinesin-2 and IFT-A act as a complex promoting nuclear localization of β-catenin during Wnt signalling

(2018) Linh T. Vuong et al.   Nature Communications

Wnt-Dependent Inactivation of the Groucho/TLE Co-repressor by the HECT E3 Ubiquitin Ligase Hyd/UBR5

(2017) Joshua E. Flack et al.   MOLECULAR CELL

Intestinal stem cell overproliferation resulting from inactivation of the APC tumor suppressor requires the transcription cofactors Earthbound and Erect wing

(2017) Ai Tian et al.   PLoS Genetics

Probing the canonicity of the Wnt/Wingless signaling pathway

(2017) Alexandra Franz et al.   PLoS Genetics

Constitutive scaffolding of multiple Wnt enhanceosome components by Legless/BCL9

(2017) Laurens M van Tienen et al.   eLife

Distinct hydrophobic “patches” in the N- and C-tails of beta-catenin contribute to nuclear transport

(2016) Manisha Sharma et al.   EXPERIMENTAL CELL RESEARCH

TCF/LEF Transcription Factors: An Update from the Internet Resources

(2016) Dusan Hrckulak et al.   Cancers

An ancient Pygo-dependent Wnt enhanceosome integrated by Chip/LDB-SSDP

(2015) Marc Fiedler et al.   eLife

Molecular functions of the TLE tetramerization domain in Wnt target gene repression

(2014) J. V. Chodaparambil et al.   EMBO JOURNAL

Distinct DNA Binding Sites Contribute to the TCF Transcriptional Switch in C. elegans and Drosophila

(2014) Chandan Bhambhani et al.   PLoS Genetics

Wnt-Mediated Repression via Bipartite DNA Recognition by TCF in the Drosophila Hematopoietic System

(2014) Chen U. Zhang et al.   PLoS Genetics

The Sox Family of Transcription Factors: Versatile Regulators of Stem and Progenitor Cell Fate

(2013) Abby Sarkar et al.   Cell Stem Cell

HIF-1α Inhibits Wnt Signaling Pathway by Activating Sost Expression in Osteoblasts

(2013) Dafu Chen et al.   PLoS One

The way Wnt works: Components and mechanism

(2012) Kenyi Saito-Diaz et al.   GROWTH FACTORS

XIAP Monoubiquitylates Groucho/TLE to Promote Canonical Wnt Signaling

(2012) Alison J. Hanson et al.   MOLECULAR CELL

Targeted Disruption of the BCL9/ -Catenin Complex Inhibits Oncogenic Wnt Signaling

(2012) K. Takada et al.   Science Translational Medicine

The adjustable nucleosome: an epigenetic signaling module

(2012) Bryan M. Turner   TRENDS IN GENETICS

TCF/LEFs and Wnt Signaling in the Nucleus

(2012) K. M. Cadigan et al.   Cold Spring Harbor Perspectives in Biology

FoxO transcription factors; Regulation by AKT and 14-3-3 proteins

(2011) Guri Tzivion et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Erect Wing facilitates context-dependent Wnt/Wingless signaling by recruiting the cell-specific Armadillo-TCF adaptor Earthbound to chromatin

(2011) N. Xin et al.   DEVELOPMENT

Jerky/Earthbound facilitates cell-specific Wnt/Wingless signalling by modulating β-catenin-TCF activity

(2011) Hassina Benchabane et al.   EMBO JOURNAL

β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells

(2011) Helena J M Smartt et al.   GUT

Phosphorylation of TCF Proteins by Homeodomain-interacting Protein Kinase 2

(2011) Hiroki Hikasa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bcl9/Bcl9l Are Critical for Wnt-Mediated Regulation of Stem Cell Traits in Colon Epithelium and Adenocarcinomas

(2010) J. Deka et al.   CANCER RESEARCH

The transcriptional activity of Pygopus is enhanced by its interaction with cAMP-response-element-binding protein (CREB)-binding protein

(2009) Phillip G. P. Andrews et al.   BIOCHEMICAL JOURNAL

Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression

(2009) Laura Arce et al.   BMC CANCER

The PHD domain is required to link Drosophila Pygopus to Legless/β-catenin and not to histone H3

(2009) Roman Kessler et al.   MECHANISMS OF DEVELOPMENT

O-GlcNAc-glycosylation of β-catenin regulates its nuclear localization and transcriptional activity

(2008) Ria Sayat et al.   EXPERIMENTAL CELL RESEARCH

Interaction of FOXO with β-Catenin Inhibits β-Catenin/T Cell Factor Activity

(2008) Diana Hoogeboom et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell-Type-Specific Function of BCL9 Involves a Transcriptional Activation Domain That Synergizes with  -Catenin

(2008) C. Sustmann et al.   MOLECULAR AND CELLULAR BIOLOGY

Pygopus activates Wingless target gene transcription through the mediator complex subunits Med12 and Med13

(2008) I. Carrera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA