Mutations in Bcl9 and Pygo genes cause congenital heart defects by tissue-specific perturbation of Wnt/β-catenin signaling

Tbx5a lineage tracing shows cardiomyocyte plasticity during zebrafish heart regeneration

(2018) Héctor Sánchez-Iranzo et al.   Nature Communications

A right-handed signalling pathway drives heart looping in vertebrates

(2017) Oscar H. Ocaña et al.   NATURE

Control of potassium homeostasis is an essential function of the second messenger cyclic di-AMP inBacillus subtilis

(2017) Jan Gundlach et al.   Science Signaling

Control of potassium homeostasis is an essential function of the second messenger cyclic di-AMP inBacillus subtilis

(2017) Jan Gundlach et al.   Science Signaling

Wnt/β-catenin signaling enables developmental transitions during valvulogenesis

(2016) Fernanda M. Bosada et al.   DEVELOPMENT

Maximizing mutagenesis with solubilized CRISPR-Cas9 ribonucleoprotein complexes

(2016) Alexa Burger et al.   DEVELOPMENT

CrispRVariants charts the mutation spectrum of genome engineering experiments

(2016) Helen Lindsay et al.   NATURE BIOTECHNOLOGY

Structure-Based Design of 1,4-Dibenzoylpiperazines as β-Catenin/B-Cell Lymphoma 9 Protein–Protein Interaction Inhibitors

(2016) John A. Wisniewski et al.   ACS Medicinal Chemistry Letters

Rational Design of Selective Small-Molecule Inhibitors for β-Catenin/B-Cell Lymphoma 9 Protein–Protein Interactions

(2015) Logan R. Hoggard et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Genetic compensation induced by deleterious mutations but not gene knockdowns

(2015) Andrea Rossi et al.   NATURE

Chamber identity programs drive early functional partitioning of the heart

(2015) Christian Mosimann et al.   Nature Communications

Ventromedial hypothalamic neurons control a defensive emotion state

(2015) Prabhat S Kunwar et al.   eLife

Pax6-dependent, but β-catenin-independent, function of Bcl9 proteins in mouse lens development

(2014) Claudio Cantù et al.   GENES & DEVELOPMENT

Heritable Transmission of Stress Resistance by High Dietary Glucose in Caenorhabditis elegans

(2014) Arnaud Tauffenberger et al.   PLoS Genetics

The Pygo2-H3K4me2/3 interaction is dispensable for mouse development and Wnt signaling-dependent transcription

(2013) C. Cantu et al.   DEVELOPMENT

Highly Efficient Targeted Mutagenesis of Drosophila with the CRISPR/Cas9 System

(2013) Andrew R. Bassett et al.   Cell Reports

Concepts and Mechanisms: Crossing Host Barriers

(2013) K. S. Doran et al.   Cold Spring Harbor Perspectives in Medicine

In vivo Wnt signaling tracing through a transgenic biosensor fish reveals novel activity domains

(2012) Enrico Moro et al.   DEVELOPMENTAL BIOLOGY

1q21.1 Microduplication expression in adults

(2012) Alessia Dolcetti et al.   GENETICS IN MEDICINE

Human gene copy number spectra analysis in congenital heart malformations

(2012) Aoy Tomita-Mitchell et al.   PHYSIOLOGICAL GENOMICS

Rapid Whole-Genome Sequencing for Genetic Disease Diagnosis in Neonatal Intensive Care Units

(2012) C. J. Saunders et al.   Science Translational Medicine

Phenotype-specific effect of chromosome 1q21.1 rearrangements and GJA5 duplications in 2436 congenital heart disease patients and 6760 controls

(2011) Rachel Soemedi et al.   HUMAN MOLECULAR GENETICS

Bcl9/Bcl9l Are Critical for Wnt-Mediated Regulation of Stem Cell Traits in Colon Epithelium and Adenocarcinomas

(2010) J. Deka et al.   CANCER RESEARCH

The Multiple Phases and Faces of Wnt Signaling During Cardiac Differentiation and Development

(2010) Susanne Gessert et al.   CIRCULATION RESEARCH

Hand2 Regulates Extracellular Matrix Remodeling Essential for Gut-Looping Morphogenesis in Zebrafish

(2010) Chunyue Yin et al.   DEVELOPMENTAL CELL

BAC array CGH in patients with Velocardiofacial syndrome-like features reveals genomic aberrations on chromosome region 1q21.1

(2009) Anna Brunet et al.   BMC Medical Genetics

Heart Valve Development

(2009) Michelle D. Combs et al.   CIRCULATION RESEARCH

A co-dependent requirement of xBcl9 and Pygopus for embryonic body axis development inXenopus

(2009) Mark W. Kennedy et al.   DEVELOPMENTAL DYNAMICS

Dual role for neural crest cells during outflow tract septation in the neural crest-deficient mutantSplotch2H

(2009) Lucy Bradshaw et al.   JOURNAL OF ANATOMY

De novo copy number variants identify new genes and loci in isolated sporadic tetralogy of Fallot

(2009) Steven C Greenway et al.   NATURE GENETICS

β-Catenin hits chromatin: regulation of Wnt target gene activation

(2009) Christian Mosimann et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Recurrent Rearrangements of Chromosome 1q21.1 and Variable Pediatric Phenotypes

(2008) Heather C. Mefford et al.   NEW ENGLAND JOURNAL OF MEDICINE

High-resolution in situ hybridization to whole-mount zebrafish embryos

(2007) Christine Thisse et al.   Nature Protocols