标题
Venetoclax causes metabolic reprogramming independent of BCL-2 inhibition
作者
关键词
-
出版物
Cell Death & Disease
Volume 11, Issue 8, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-08-14
DOI
10.1038/s41419-020-02867-2
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Electron transport chain activity is a predictor and target for venetoclax sensitivity in multiple myeloma
- (2020) Richa Bajpai et al. Nature Communications
- Regulation of apoptosis in health and disease: the balancing act of BCL-2 family proteins
- (2019) Rumani Singh et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Occurrence of the potent mutagens 2- nitrobenzanthrone and 3-nitrobenzanthrone in fine airborne particles
- (2019) Aldenor G. Santos et al. Scientific Reports
- Targeting mitochondrial structure sensitizes acute myeloid leukemia to Venetoclax treatment
- (2019) Xufeng Chen et al. Cancer Discovery
- Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies
- (2019) Romain Guièze et al. CANCER CELL
- Inhibition of mitochondrial translation overcomes venetoclax resistance in AML through activation of the integrated stress response
- (2019) David Sharon et al. Science Translational Medicine
- MCL-1 is a prognostic indicator and drug target in breast cancer
- (2018) Kirsteen J. Campbell et al. Cell Death & Disease
- S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth
- (2018) Patrick Casara et al. Oncotarget
- BCL2 and BCL(X)L selective inhibitors decrease mitochondrial ATP production in breast cancer cells and are synthetically lethal when combined with 2-deoxy-D-glucose
- (2018) Federico Lucantoni et al. Oncotarget
- BH3-Mimetic Drugs: Blazing the Trail for New Cancer Medicines
- (2018) Delphine Merino et al. CANCER CELL
- Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals
- (2017) Pedro M. Quirós et al. JOURNAL OF CELL BIOLOGY
- The integrated stress response
- (2016) Karolina Pakos‐Zebrucka et al. EMBO REPORTS
- Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane
- (2016) Katelyn L. O'Neill et al. GENES & DEVELOPMENT
- The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models
- (2016) András Kotschy et al. NATURE
- Targeting BCL2 with Venetoclax in Relapsed Chronic Lymphocytic Leukemia
- (2016) Andrew W. Roberts et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mitochondrial dysfunction enhances cisplatin resistance in human gastric cancer cells via the ROS-activated GCN2-eIF2α-ATF4-xCT pathway
- (2016) Sheng-Fan Wang et al. Oncotarget
- The Spectrum of Mitochondrial Ultrastructural Defects in Mitochondrial Myopathy
- (2016) Amy E. Vincent et al. Scientific Reports
- Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis
- (2015) Simone Cardaci et al. NATURE CELL BIOLOGY
- Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice
- (2015) T. Wai et al. SCIENCE
- Integrated stress response is critical for gemcitabine resistance in pancreatic ductal adenocarcinoma
- (2015) L R Palam et al. Cell Death & Disease
- Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency
- (2013) Sara Cogliati et al. CELL
- BCL-2 Inhibition Targets Oxidative Phosphorylation and Selectively Eradicates Quiescent Human Leukemia Stem Cells
- (2013) Eleni D. Lagadinou et al. Cell Stem Cell
- ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets
- (2013) Andrew J Souers et al. NATURE MEDICINE
- A Role for Cytosolic Fumarate Hydratase in Urea Cycle Metabolism and Renal Neoplasia
- (2013) Julie Adam et al. Cell Reports
- A Unified Model of Mammalian BCL-2 Protein Family Interactions at the Mitochondria
- (2011) Fabien Llambi et al. MOLECULAR CELL
- Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase
- (2011) Christian Frezza et al. NATURE
- UOK 262 cell line, fumarate hydratase deficient (FH−/FH−) hereditary leiomyomatosis renal cell carcinoma: in vitro and in vivo model of an aberrant energy metabolic pathway in human cancer
- (2009) Youfeng Yang et al. CANCER GENETICS AND CYTOGENETICS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search