Remodeling the epigenome and (epi)cytoskeleton: a new paradigm for co-regulation by methylation

Phenotypic Switching Resulting From Developmental Plasticity: Fixed or Reversible?

(2020) Warren W. Burggren   Frontiers in Physiology

Effects of α-tubulin acetylation on microtubule structure and stability

(2019) Lisa Eshun-Wilson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural insights into SETD3-mediated histidine methylation on β-actin

(2019) Qiong Guo et al.   eLife

Quantitative high-precision imaging of myosin-dependent filamentous actin dynamics

(2019) Sawako Yamashiro et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

The role of mutation bias in adaptive molecular evolution: insights from convergent changes in protein function

(2019) Jay F. Storz et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Molecular mechanisms of epigenetic inheritance: Possible evolutionary implications

(2019) Peter Sarkies   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape

(2019) Daniel N. Weinberg et al.   NATURE

Quantification of Tau Protein Lysine Methylation in Aging and Alzheimer’s Disease

(2019) Carol J. Huseby et al.   JOURNAL OF ALZHEIMERS DISEASE

Microtubule-Associated Proteins: Structuring the Cytoskeleton

(2019) Satish Bodakuntla et al.   TRENDS IN CELL BIOLOGY

Structural basis for the target specificity of actin histidine methyltransferase SETD3

(2019) Shaobo Dai et al.   Nature Communications

SETD2 Haploinsufficiency for Microtubule Methylation is an Early Driver of Genomic Instability in Renal Cell Carcinoma

(2018) Yun Chen Chiang et al.   CANCER RESEARCH

Tubulin Posttranslational Modifications and Emerging Links to Human Disease

(2018) Maria M. Magiera et al.   CELL

Arginine Methylation by PRMT2 Controls the Functions of the Actin Nucleator Cobl

(2018) Wenya Hou et al.   DEVELOPMENTAL CELL

Evolutionary analysis indicates that DNA alkylation damage is a byproduct of cytosine DNA methyltransferase activity

(2018) Silvana Rošić et al.   NATURE GENETICS

Actin Remodeling in Regulated Exocytosis: Toward a Mesoscopic View

(2018) Pin Li et al.   TRENDS IN CELL BIOLOGY

Moonlighting with WDR5: A Cellular Multitasker

(2018) Alissa Guarnaccia et al.   Journal of Clinical Medicine

Modes of Interaction of KMT2 Histone H3 Lysine 4 Methyltransferase/COMPASS Complexes with Chromatin

(2018) Agnieszka Bochyńska et al.   Cells

WDR5 Stabilizes Actin Architecture to Promote Multiciliated Cell Formation

(2018) Saurabh S. Kulkarni et al.   DEVELOPMENTAL CELL

Epigenetic tools (The Writers, The Readers and The Erasers) and their implications in cancer therapy

(2018) Subhankar Biswas et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

SETD3 is an actin histidine methyltransferase that prevents primary dystocia

(2018) Alex W. Wilkinson et al.   NATURE

Intergenerational and transgenerational epigenetic inheritance in animals

(2018) Marcos Francisco Perez et al.   NATURE CELL BIOLOGY

PRMT2 links histone H3R8 asymmetric dimethylation to oncogenic activation and tumorigenesis of glioblastoma

(2018) Feng Dong et al.   Nature Communications

SETD3 protein is the actin-specific histidine N-methyltransferase

(2018) Sebastian Kwiatkowski et al.   eLife

EZH2-mediated α-actin methylation needs lncRNA TUG1, and promotes the cortex cytoskeleton formation in VSMCs

(2017) Rong Chen et al.   GENE

Tubulin Post-Translational Modifications and Microtubule Dynamics

(2017) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cross-talk between the H3K36me3 and H4K16ac histone epigenetic marks in DNA double-strand break repair

(2017) Lin Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The tubulin code at a glance

(2017) Sudarshan Gadadhar et al.   JOURNAL OF CELL SCIENCE

Actin assembly mechanisms at a glance

(2017) Klemens Rottner et al.   JOURNAL OF CELL SCIENCE

The evolutionary implications of epigenetic inheritance

(2017) Eva Jablonka   Interface Focus

Acetylation- and Methylation-Related Epigenetic Proteins in the Context of Their Targets

(2017) et al.   Genes

The growing landscape of tubulin acetylation: lysine 40 and many more

(2016) K. Sadoul et al.   BIOCHEMICAL JOURNAL

Microtubules in health and degenerative disease of the nervous system

(2016) Andrew J. Matamoros et al.   BRAIN RESEARCH BULLETIN

Dual Chromatin and Cytoskeletal Remodeling by SETD2

(2016) In Young Park et al.   CELL

Structure/Function Analysis of Recurrent Mutations in SETD2 Protein Reveals a Critical and Conserved Role for a SET Domain Residue in Maintaining Protein Stability and Histone H3 Lys-36 Trimethylation

(2016) Kathryn E. Hacker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Aging Epigenome

(2016) Lauren N. Booth et al.   MOLECULAR CELL

Minireview: Epigenomic Plasticity and Vulnerability to EDC Exposures

(2016) Cheryl Lyn Walker   MOLECULAR ENDOCRINOLOGY

From profiles to function in epigenomics

(2016) Stefan H. Stricker et al.   NATURE REVIEWS GENETICS

The Tubulin Code: A Navigation System for Chromosomes during Mitosis

(2016) Marin Barisic et al.   TRENDS IN CELL BIOLOGY

H3K9me3-Dependent Heterochromatin: Barrier to Cell Fate Changes

(2016) Justin S. Becker et al.   TRENDS IN GENETICS

Evolution of Epigenetic Regulation in Vertebrate Genomes

(2016) Rebecca F. Lowdon et al.   TRENDS IN GENETICS

Actin and Actin-Binding Proteins

(2016) Thomas D. Pollard   Cold Spring Harbor Perspectives in Biology

Epigenetic Inheritance across the Landscape

(2016) Amy V. Whipple et al.   Frontiers in Genetics

Natural compound-derived epigenetic regulators targeting epigenetic readers, writers and erasers

(2015) Anne Yuqing Yang et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Environmental Epigenetics and a Unified Theory of the Molecular Aspects of Evolution: A Neo-Lamarckian Concept that Facilitates Neo-Darwinian Evolution

(2015) M. K. Skinner   Genome Biology and Evolution

WD Repeat-containing Protein 5 (WDR5) Localizes to the Midbody and Regulates Abscission

(2015) Jeffrey K. Bailey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epigenetics and locust life phase transitions

(2015) U. R. Ernst et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin

(2015) Merry Gunawan et al.   NATURE IMMUNOLOGY

Comparative epigenomics: a powerful tool to understand the evolution of DNA methylation

(2015) Xuehua Zhong   NEW PHYTOLOGIST

Rate, spectrum, and evolutionary dynamics of spontaneous epimutations

(2015) Adriaan van der Graaf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of epigenetic “readers, writers and erasers”: Implications for developmental reprogramming and the epigenetic basis for health and disease

(2015) Lindsey S. Treviño et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Post-translational modifications of tubulin: pathways to functional diversity of microtubules

(2015) Yuyu Song et al.   TRENDS IN CELL BIOLOGY

In vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse

(2015) Marco Morselli et al.   eLife

Past, present, and future of epigenetics applied to livestock breeding

(2015) Oscar González-Recio et al.   Frontiers in Genetics

Lysine methylation is an endogenous post-translational modification of tau protein in human brain and a modulator of aggregation propensity

(2014) Kristen E. Funk et al.   BIOCHEMICAL JOURNAL

Effects of α-Tubulin K40 Acetylation and Detyrosination on Kinesin-1 Motility in a Purified System

(2014) Neha Kaul et al.   BIOPHYSICAL JOURNAL

Molecular mechanisms and functional implications of polarized actin remodeling at the T cell immunological synapse

(2014) Audrey Le Floc’h et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Epigenetics in Comparative Biology: Why We Should Pay Attention

(2014) W. W. Burggren et al.   INTEGRATIVE AND COMPARATIVE BIOLOGY

The tubulin code: Molecular components, readout mechanisms, and functions

(2014) Carsten Janke   JOURNAL OF CELL BIOLOGY

Nature, nurture and epigenetics

(2014) David Crews et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Epigenetic Inheritance, Epimutation, and the Response to Selection

(2014) Robert E. Furrow   PLoS One

SETD2-Dependent Histone H3K36 Trimethylation Is Required for Homologous Recombination Repair and Genome Stability

(2014) Sophia X. Pfister et al.   Cell Reports

SETD2 is required for DNA double-strand break repair and activation of the p53-mediated checkpoint

(2014) Sílvia Carvalho et al.   eLife

Decoding the Histone Code: Role of H3K36me3 in Mismatch Repair and Implications for Cancer Susceptibility and Therapy

(2013) G.-M. Li   CANCER RESEARCH

Phenotypic Transformation Affects Associative Learning in the Desert Locust

(2013) Patrício M.V. Simões et al.   CURRENT BIOLOGY

Cytoplasmic protein methylation is essential for neural crest migration

(2013) Katie L. Vermillion et al.   JOURNAL OF CELL BIOLOGY

Effects of tubulin acetylation and tubulin acetyltransferase binding on microtubule structure

(2013) Stuart C. Howes et al.   MOLECULAR BIOLOGY OF THE CELL

The COMPASS Family of Histone H3K4 Methylases: Mechanisms of Regulation in Development and Disease Pathogenesis

(2012) Ali Shilatifard   Annual Review of Biochemistry

Post-translational modification and regulation of actin

(2012) Jonathan R Terman et al.   CURRENT OPINION IN CELL BIOLOGY

Histone deacetylase 6 plays a role as a distinct regulator of diverse cellular processes

(2012) Yingxiu Li et al.   FEBS Journal

Understanding the language of Lys36 methylation at histone H3

(2012) Eric J. Wagner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Symmetric dimethylation of H3R2 is a newly identified histone mark that supports euchromatin maintenance

(2012) Valentina Migliori et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Tubulin Acetylation Alone Does Not Affect Kinesin-1 Velocity and Run Length In Vitro

(2012) Wilhelm J. Walter et al.   PLoS One

Deficiency in DNA methylation increases meiotic crossover rates in euchromatic but not in heterochromatic regions in Arabidopsis

(2012) C. Melamed-Bessudo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The penetrance of an epigenetic trait in mice is progressively yet reversibly increased by selection and environment

(2012) J. E. Cropley et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Actin Structure and Function

(2011) Roberto Dominguez et al.   Annual Review of Biophysics

Histone Methyltransferase SETD3 Regulates Muscle Differentiation

(2011) Gwang Hyeon Eom et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell mechanics and the cytoskeleton

(2010) Daniel A. Fletcher et al.   NATURE

Repressive and active histone methylation mark distinct promoters in human and mouse spermatozoa

(2010) Urszula Brykczynska et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes

(2010) Diego Pasini et al.   NUCLEIC ACIDS RESEARCH

Methylation of histone H3 lysine 36 enhances DNA repair by nonhomologous end-joining

(2010) S. Fnu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kinetic analysis of human protein arginine N-methyltransferase 2: formation of monomethyl- and asymmetric dimethyl-arginine residues on histone H4

(2009) Ted M. Lakowski et al.   BIOCHEMICAL JOURNAL

Single Molecule Imaging Reveals Differences in Microtubule Track Selection Between Kinesin Motors

(2009) Dawen Cai et al.   PLOS BIOLOGY

Epigenetic interplay between histone modifications and DNA methylation in gene silencing

(2008) T VAISSIERE et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH