SETD2 is required for DNA double-strand break repair and activation of the p53-mediated checkpoint

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Mutations in SETD2 and genes affecting histone H3K36 methylation target hemispheric high-grade gliomas

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The Histone Mark H3K36me3 Regulates Human DNA Mismatch Repair through Its Interaction with MutSα

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Targeting histone modifications—epigenetics in cancer

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Exomic analysis of myxoid liposarcomas, synovial sarcomas, and osteosarcomas

(2013) Christine G. Joseph et al.   GENES CHROMOSOMES & CANCER

Histone Acetyltransferase 1 Promotes Homologous Recombination in DNA Repair by Facilitating Histone Turnover

(2013) Xiaohan Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone chaperone FACT regulates homologous recombination by chromatin remodeling through interaction with RNF20

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Comprehensive molecular characterization of clear cell renal cell carcinoma

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(2013) Yusuke Sato et al.   NATURE GENETICS

Histone methyltransferase SETD2 coordinates FACT recruitment with nucleosome dynamics during transcription

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Prime, Repair, Restore: The Active Role of Chromatin in the DNA Damage Response

(2012) Gaston Soria et al.   MOLECULAR CELL

Playing the End Game: DNA Double-Strand Break Repair Pathway Choice

(2012) J. Ross Chapman et al.   MOLECULAR CELL

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

(2012) Jinghui Zhang et al.   NATURE

Chromatin and the genome integrity network

(2012) Manolis Papamichos-Chronakis et al.   NATURE REVIEWS GENETICS

DNA damage checkpoints in stem cells, ageing and cancer

(2012) Tobias Sperka et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

LEDGF (p75) promotes DNA-end resection and homologous recombination

(2012) Mads Daugaard et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The H2B ubiquitin ligase RNF40 cooperates with SUPT16H to induce dynamic changes in chromatin structure during DNA double-strand break repair

(2011) Vijayalakshmi Kari et al.   CELL CYCLE

Histone tails: Directing the chromatin response to DNA damage

(2011) Roger A. Greenberg   FEBS LETTERS

MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites

(2011) Huadong Pei et al.   NATURE

Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

(2011) Ignacio Varela et al.   NATURE

More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance

(2011) Jiri Lukas et al.   NATURE CELL BIOLOGY

The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway

(2010) Michael R. Lieber   Annual Review of Biochemistry

Histone Methyltransferase Gene SETD2 Is a Novel Tumor Suppressor Gene in Clear Cell Renal Cell Carcinoma

(2010) Gerben Duns et al.   CANCER RESEARCH

53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks

(2010) Samuel F. Bunting et al.   CELL

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

(2010) Gillian L. Dalgliesh et al.   NATURE

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

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53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

(2010) Peter Bouwman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Single-Stranded DNA Orchestrates an ATM-to-ATR Switch at DNA Breaks

(2009) Bunsyo Shiotani et al.   MOLECULAR CELL

Mechanism of Eukaryotic Homologous Recombination

(2008) Joseph San Filippo et al.   Annual Review of Biochemistry

Histone methyltransferase protein SETD2 interacts with p53 and selectively regulates its downstream genes

(2008) Ping Xie et al.   CELLULAR SIGNALLING