标题
Targeting MmpL3 for anti-tuberculosis drug development
作者
关键词
-
出版物
BIOCHEMICAL SOCIETY TRANSACTIONS
Volume -, Issue -, Pages -
出版商
Portland Press Ltd.
发表日期
2020-07-14
DOI
10.1042/bst20190950
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Repurposed drug candidates for antituberculosis therapy
- (2020) Qi An et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Photoactivatable Glycolipid Probes for Identifying Mycolate–Protein Interactions in Live Mycobacteria
- (2020) Herbert W. Kavunja et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Structural Basis for the Inhibition of Mycobacterial MmpL3 by NITD-349 and SPIRO
- (2020) Xiaolin Yang et al. JOURNAL OF MOLECULAR BIOLOGY
- Direct Inhibition of MmpL3 by Novel Antitubercular Compounds
- (2019) Wei Li et al. ACS Infectious Diseases
- Mass spectrometry: From plasma proteins to mitochondrial membranes
- (2019) Carol V. Robinson PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target
- (2019) Bing Zhang et al. CELL
- Membrane Protein–Lipid Interactions Probed Using Mass Spectrometry
- (2019) Jani Reddy Bolla et al. Annual Review of Biochemistry
- MmpL3 is a lipid transporter that binds trehalose monomycolate and phosphatidylethanolamine
- (2019) Chih-Chia Su et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Two Accessory Proteins Govern MmpL3 Mycolic Acid Transport in Mycobacteria
- (2019) Allison Fay et al. mBio
- The MmpL3 interactome reveals a complex crosstalk between cell envelope biosynthesis and cell elongation and division in mycobacteria
- (2019) Juan Manuel Belardinelli et al. Scientific Reports
- Identification of New MmpL3 Inhibitors by Untargeted and Targeted Mutant Screens Defines MmpL3 Domains with Differential Resistance
- (2019) John T. Williams et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Transport mechanism of Mycobacterium tuberculosis MmpL/S family proteins and implications in pharmaceutical targeting
- (2019) Shuang Ma et al. BIOLOGICAL CHEMISTRY
- Structural and functional evidence that lipoprotein LpqN supports cell envelope biogenesis in Mycobacterium tuberculosis
- (2019) Geoff C. Melly et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The crystal structure of the mycobacterial trehalose monomycolate transport factor A, TtfA, reveals an atypical fold
- (2019) Kien Lam Ung et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- HC2091 Kills Mycobacterium tuberculosis by Targeting the MmpL3 Mycolic Acid Transporter
- (2018) Huiqing Zheng et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Novel Acetamide Indirectly Targets Mycobacterial Transporter MmpL3 by Proton Motive Force Disruption
- (2018) Annanya Shetty et al. Frontiers in Microbiology
- Crystal structures of theBurkholderia multivoranshopanoid transporter HpnN
- (2017) Nitin Kumar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MmpL3 is the flippase for mycolic acids in mycobacteria
- (2017) Zhujun Xu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tuberculosis — drugs in the 2016 development pipeline
- (2017) Barbara E. Laughon et al. Nature Reviews Disease Primers
- Trehalose dimycolate interferes with FcγR-mediated phagosome maturation through Mincle, SHP-1 and FcγRIIB signalling
- (2017) Emmanuel C. Patin et al. PLoS One
- Essentiality of mmpL3 and impact of its silencing on Mycobacterium tuberculosis gene expression
- (2017) Giulia Degiacomi et al. Scientific Reports
- Dissecting the mycobacterial cell envelope and defining the composition of the native mycomembrane
- (2017) Laura Chiaradia et al. Scientific Reports
- A sliding selectivity scale for lipid binding to membrane proteins
- (2016) Michael Landreh et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- MmpL3 Inhibitors: Diverse Chemical Scaffolds Inhibit the Same Target
- (2016) Giovanna Poce et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- A new piperidinol derivative targeting mycolic acid transport inMycobacterium abscessus
- (2016) Christian Dupont et al. MOLECULAR MICROBIOLOGY
- MmpL transporter-mediated export of cell-wall associated lipids and siderophores in mycobacteria
- (2016) Christian Chalut TUBERCULOSIS
- Diphenylether-Modified 1,2-Diamines with Improved Drug Properties for Development against Mycobacterium tuberculosis
- (2016) Marie H. Foss et al. ACS Infectious Diseases
- Structure–Function Profile of MmpL3, the Essential Mycolic Acid Transporter from Mycobacterium tuberculosis
- (2016) Juan Manuel Belardinelli et al. ACS Infectious Diseases
- Lipid transport in Mycobacterium tuberculosis and its implications in virulence and drug development
- (2015) Rebeca Bailo et al. BIOCHEMICAL PHARMACOLOGY
- Insights into the smooth-to-rough transitioning in Mycobacterium bolletii unravels a functional Tyr residue conserved in all mycobacterial MmpL family members
- (2015) Audrey Bernut et al. MOLECULAR MICROBIOLOGY
- Heavy metal transport by the CusCFBA efflux system
- (2015) Jared A. Delmar et al. PROTEIN SCIENCE
- Cross-Resistance between Clofazimine and Bedaquiline through Upregulation of MmpL5 in Mycobacterium tuberculosis
- (2014) R. C. Hartkoorn et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Novel Insights into the Mechanism of Inhibition of MmpL3, a Target of Multiple Pharmacophores in Mycobacterium tuberculosis
- (2014) Wei Li et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- The ThreeMycobacterium tuberculosisAntigen 85 Isoforms Have Unique Substrates and Activities Determined by Non-active Site Regions
- (2014) Keriann M. Backus et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Multitarget Drug Discovery for Tuberculosis and Other Infectious Diseases
- (2014) Kai Li et al. JOURNAL OF MEDICINAL CHEMISTRY
- Structure of the AcrAB–TolC multidrug efflux pump
- (2014) Dijun Du et al. NATURE
- How sisters grow apart: mycobacterial growth and division
- (2014) Karen J. Kieser et al. NATURE REVIEWS MICROBIOLOGY
- Multi-drug-resistant tuberculosis in HIV positive patients in Eastern Europe
- (2013) Frank A. Post et al. JOURNAL OF INFECTION
- Tetrahydropyrazolo[1,5-a]Pyrimidine-3-Carboxamide and N-Benzyl-6′,7′-Dihydrospiro[Piperidine-4,4′-Thieno[3,2-c]Pyran] Analogues with Bactericidal Efficacy against Mycobacterium tuberculosis Targeting MmpL3
- (2013) Modesto J. Remuiñán et al. PLoS One
- Indolcarboxamide Is a Preclinical Candidate for Treating Multidrug-Resistant Tuberculosis
- (2013) S. P. S. Rao et al. Science Translational Medicine
- Indoleamides are active against drug-resistant Mycobacterium tuberculosis
- (2013) Shichun Lun et al. Nature Communications
- Identification of Novel Inhibitors of M. tuberculosis Growth Using Whole Cell Based High-Throughput Screening
- (2012) Sarah A. Stanley et al. ACS Chemical Biology
- SQ109 Targets MmpL3, a Membrane Transporter of Trehalose Monomycolate Involved in Mycolic Acid Donation to the Cell Wall Core of Mycobacterium tuberculosis
- (2012) Kapil Tahlan et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- MmpL Genes Are Associated with Mycolic Acid Metabolism in Mycobacteria and Corynebacteria
- (2012) Cristian Varela et al. CHEMISTRY & BIOLOGY
- Nonprotein Structures from Mycobacteria: Emerging Actors for Tuberculosis Control
- (2012) Luz M. Lopez-Marin Clinical & Developmental Immunology
- Discovery and development of SQ109: a new antitubercular drug with a novel mechanism of action
- (2012) Katherine A Sacksteder et al. Future Microbiology
- Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane
- (2012) Anna E Grzegorzewicz et al. Nature Chemical Biology
- Advances in the Mass Spectrometry of Membrane Proteins: From Individual Proteins to Intact Complexes
- (2011) Nelson P. Barrera et al. Annual Review of Biochemistry
- MmpL3 Is the Cellular Target of the Antitubercular Pyrrole Derivative BM212
- (2011) Valentina La Rosa et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Contribution of efflux activity to isoniazid resistance in the Mycobacterium tuberculosis complex
- (2011) Liliana Rodrigues et al. INFECTION GENETICS AND EVOLUTION
- Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosis
- (2010) Neel R Gandhi et al. LANCET
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now