Novel Acetamide Indirectly Targets Mycobacterial Transporter MmpL3 by Proton Motive Force Disruption
出版年份 2018 全文链接
标题
Novel Acetamide Indirectly Targets Mycobacterial Transporter MmpL3 by Proton Motive Force Disruption
作者
关键词
-
出版物
Frontiers in Microbiology
Volume 9, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2018-12-04
DOI
10.3389/fmicb.2018.02960
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- HC2091 Kills Mycobacterium tuberculosis by Targeting the MmpL3 Mycolic Acid Transporter
- (2018) Huiqing Zheng et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Amphiphilic Indole Derivatives as Antimycobacterial Agents: Structure–Activity Relationships and Membrane Targeting Properties
- (2017) Tianming Yang et al. JOURNAL OF MEDICINAL CHEMISTRY
- MmpL3 is the flippase for mycolic acids in mycobacteria
- (2017) Zhujun Xu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Essentiality of mmpL3 and impact of its silencing on Mycobacterium tuberculosis gene expression
- (2017) Giulia Degiacomi et al. Scientific Reports
- Therapeutic Potential of the Mycobacterium tuberculosis Mycolic Acid Transporter, MmpL3
- (2016) Wei Li et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Membrane-targeting AM-0016 kills mycobacterial persisters and shows low propensity for resistance development
- (2016) Devika Mukherjee et al. Future Microbiology
- Structure–Function Profile of MmpL3, the Essential Mycolic Acid Transporter from Mycobacterium tuberculosis
- (2016) Juan Manuel Belardinelli et al. ACS Infectious Diseases
- THPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteria
- (2016) Jonathan A. G. Cox et al. Nature Microbiology
- The Mycobacterial Cell Wall—Peptidoglycan and Arabinogalactan
- (2015) Luke J. Alderwick et al. Cold Spring Harbor Perspectives in Medicine
- Novel Insights into the Mechanism of Inhibition of MmpL3, a Target of Multiple Pharmacophores in Mycobacterium tuberculosis
- (2014) Wei Li et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Reduced Drug Uptake in Phenotypically Resistant Nutrient-Starved Nonreplicating Mycobacterium tuberculosis
- (2013) Jansy Sarathy et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Kinetic mechanism and inhibition ofMycobacterium tuberculosisd-alanine:d-alanine ligase by the antibioticd-cycloserine
- (2013) Gareth A. Prosser et al. FEBS Journal
- Design, Synthesis, and Biological Evaluation of Indole-2-carboxamides: A Promising Class of Antituberculosis Agents
- (2013) Ravinder Reddy Kondreddi et al. JOURNAL OF MEDICINAL CHEMISTRY
- Tetrahydropyrazolo[1,5-a]Pyrimidine-3-Carboxamide and N-Benzyl-6′,7′-Dihydrospiro[Piperidine-4,4′-Thieno[3,2-c]Pyran] Analogues with Bactericidal Efficacy against Mycobacterium tuberculosis Targeting MmpL3
- (2013) Modesto J. Remuiñán et al. PLoS One
- Identification of New Drug Targets and Resistance Mechanisms in Mycobacterium tuberculosis
- (2013) Thomas R. Ioerger et al. PLoS One
- Indolcarboxamide Is a Preclinical Candidate for Treating Multidrug-Resistant Tuberculosis
- (2013) S. P. S. Rao et al. Science Translational Medicine
- Indoleamides are active against drug-resistant Mycobacterium tuberculosis
- (2013) Shichun Lun et al. Nature Communications
- Identification of Novel Inhibitors of M. tuberculosis Growth Using Whole Cell Based High-Throughput Screening
- (2012) Sarah A. Stanley et al. ACS Chemical Biology
- SQ109 Targets MmpL3, a Membrane Transporter of Trehalose Monomycolate Involved in Mycolic Acid Donation to the Cell Wall Core of Mycobacterium tuberculosis
- (2012) Kapil Tahlan et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Streptomycin-Starved Mycobacterium tuberculosis 18b, a Drug Discovery Tool for Latent Tuberculosis
- (2012) Ming Zhang et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Metabolism of the Antituberculosis Drug Ethionamide
- (2012) Nuno Vale et al. CURRENT DRUG METABOLISM
- Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane
- (2012) Anna E Grzegorzewicz et al. Nature Chemical Biology
- MmpL3 Is the Cellular Target of the Antitubercular Pyrrole Derivative BM212
- (2011) Valentina La Rosa et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Lipoarabinomannan Localization and Abundance during Growth of Mycobacterium smegmatis
- (2011) R. K. Dhiman et al. JOURNAL OF BACTERIOLOGY
- Time-kill kinetics of anti-tuberculosis drugs, and emergence of resistance, in relation to metabolic activity of Mycobacterium tuberculosis
- (2010) J. E. M. de Steenwinkel et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Discovery of dipiperidines as new antitubercular agents
- (2009) Elena Bogatcheva et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Nutrient-starved, non-replicating Mycobacterium tuberculosis requires respiration, ATP synthase and isocitrate lyase for maintenance of ATP homeostasis and viability
- (2009) M. Gengenbacher et al. MICROBIOLOGY-SGM
- Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis
- (2009) V. Makarov et al. SCIENCE
- Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances
- (2008) Irith Wiegand et al. Nature Protocols
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started