Role of Endoplasmic Reticulum Stress Sensor IRE1α in Cellular Physiology, Calcium, ROS Signaling, and Metaflammation
出版年份 2020 全文链接
标题
Role of Endoplasmic Reticulum Stress Sensor IRE1α in Cellular Physiology, Calcium, ROS Signaling, and Metaflammation
作者
关键词
-
出版物
Cells
Volume 9, Issue 5, Pages 1160
出版商
MDPI AG
发表日期
2020-05-08
DOI
10.3390/cells9051160
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics
- (2019) Amado Carreras-Sureda et al. NATURE CELL BIOLOGY
- PRKCSH contributes to tumorigenesis by selective boosting of IRE1 signaling pathway
- (2019) Gu-Choul Shin et al. Nature Communications
- Interactome Screening Identifies the ER Luminal Chaperone Hsp47 as a Regulator of the Unfolded Protein Response Transducer IRE1α
- (2018) Denisse Sepulveda et al. MOLECULAR CELL
- IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A
- (2018) Hery Urra et al. NATURE CELL BIOLOGY
- The requirement of IRE1 and XBP1 in resolving physiological stress duringDrosophiladevelopment
- (2017) Huai-Wei Huang et al. JOURNAL OF CELL SCIENCE
- IRS posttranslational modifications in regulating insulin signaling
- (2017) Jinghua Peng et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- Inflammation, metaflammation and immunometabolic disorders
- (2017) Gökhan S. Hotamisligil NATURE
- Targeting IRE1 with small molecules counteracts progression of atherosclerosis
- (2017) Ozlem Tufanli et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- IRE1α promotes viral infection by conferring resistance to apoptosis
- (2017) Susan L. Fink et al. Science Signaling
- Fortilin binds IRE1α and prevents ER stress from signaling apoptotic cell death
- (2017) Decha Pinkaew et al. Nature Communications
- Endotoxemia-mediated activation of acetyltransferase P300 impairs insulin signaling in obesity
- (2017) Jia Cao et al. Nature Communications
- A critical role of DDRGK1 in endoplasmic reticulum homoeostasis via regulation of IRE1α stability
- (2017) Jiang Liu et al. Nature Communications
- Reduced Insulin/Insulin-Like Growth Factor Receptor Signaling Mitigates Defective Dendrite Morphogenesis in Mutants of the ER Stress Sensor IRE-1
- (2017) Yehuda Salzberg et al. PLoS Genetics
- An unfolded protein-induced conformational switch activates mammalian IRE1
- (2017) G Elif Karagöz et al. eLife
- The Sec61 translocon limits IRE1α signaling during the unfolded protein response
- (2017) Arunkumar Sundaram et al. eLife
- IRE1α promotes viral infection by conferring resistance to apoptosis
- (2017) Susan L. Fink et al. Science Signaling
- Diabetic Cardiomyopathy: An Immunometabolic Perspective
- (2017) Paras K. Mishra et al. Frontiers in Endocrinology
- High-fat diet-induced obesity impairs insulin signaling in lungs of allergen-challenged mice: Improvement by resveratrol
- (2017) Diana M. André et al. Scientific Reports
- Structural and Functional Analysis of the Allosteric Inhibition of IRE1α with ATP-Competitive Ligands
- (2016) Hannah C. Feldman et al. ACS Chemical Biology
- Arabidopsis tRNA ligase completes the cytoplasmic splicing of bZIP60 mRNA in the unfolded protein response
- (2016) Yukihiro Nagashima et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- IRE1α Signaling Pathways Involved in Mammalian Cell Fate Determination
- (2016) Jie Wu et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Structural Insights into IRE1 Functions in the Unfolded Protein Response
- (2016) Jianqiong Yang et al. CURRENT MEDICINAL CHEMISTRY
- Inositol-Requiring Enzyme 1 Facilitates Diabetic Wound Healing Through Modulating MicroRNAs
- (2016) Jie-Mei Wang et al. DIABETES
- Ubiquitin D Regulates IRE1α/c-Jun N-terminal Kinase (JNK) Protein-dependent Apoptosis in Pancreatic Beta Cells
- (2016) Flora Brozzi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- XBP1s Is an Anti-lipogenic Protein
- (2016) Hilde Herrema et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ire1 supports normal ER differentiation in developingDrosophilaphotoreceptors
- (2016) Zuyuan Xu et al. JOURNAL OF CELL SCIENCE
- Terpene glycoside component from Moutan Cortex ameliorates diabetic nephropathy by regulating endoplasmic reticulum stress-related inflammatory responses
- (2016) Juan Chen et al. JOURNAL OF ETHNOPHARMACOLOGY
- Hepatic deletion of X-box binding protein 1 impairs bile acid metabolism in mice
- (2016) Xiaoying Liu et al. JOURNAL OF LIPID RESEARCH
- Cysteine Sulfenylation Directs IRE-1 to Activate the SKN-1/Nrf2 Antioxidant Response
- (2016) John M. Hourihan et al. MOLECULAR CELL
- NOD1 and NOD2 signalling links ER stress with inflammation
- (2016) A. Marijke Keestra-Gounder et al. NATURE
- Prevention of atherosclerosis by bioactive palmitoleate through suppression of organelle stress and inflammasome activation
- (2016) Ismail Çimen et al. Science Translational Medicine
- Pathogenic Mechanism of Diabetes Development Due to Dysfunction of Unfolded Protein Response
- (2016) Yuichi Tsuchiya et al. YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN
- Novel mechanism of enhancing IRE1α-XBP1 signalling via the PERK-ATF4 pathway
- (2016) Akio Tsuru et al. Scientific Reports
- Structural Basis for Regulation of RNA-Binding Proteins by Phosphorylation
- (2015) Roopa Thapar ACS Chemical Biology
- IRE1 impairs insulin signaling transduction of fructose-fed mice via JNK independent of excess lipid
- (2015) Ruo-Qiong Sun et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Imaging of single cell responses to ER stress indicates that the relative dynamics of IRE1/XBP1 and PERK/ATF4 signalling rather than a switch between signalling branches determine cell survival
- (2015) F Walter et al. CELL DEATH AND DIFFERENTIATION
- PHLDA3 overexpression in hepatocytes by endoplasmic reticulum stress via IRE1–Xbp1s pathway expedites liver injury
- (2015) Chang Yeob Han et al. GUT
- Tight regulation of the unfolded protein sensor Ire1 by its intramolecularly antagonizing subdomain
- (2015) R. Mathuranyanon et al. JOURNAL OF CELL SCIENCE
- IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis
- (2015) Takahide Tohmonda et al. JOURNAL OF CLINICAL INVESTIGATION
- Role for the endoplasmic reticulum stress sensor IRE1α in liver regenerative responses
- (2015) Yang Liu et al. JOURNAL OF HEPATOLOGY
- Endoplasmic Reticulum Stress–Induced IRE1α Activation Mediates Cross-Talk of GSK-3β and XBP-1 To Regulate Inflammatory Cytokine Production
- (2015) Sena Kim et al. JOURNAL OF IMMUNOLOGY
- Polypeptide from Chlamys farreri suppresses ultraviolet-B irradiation-induced apoptosis through restoring ER redox homeostasis, scavenging ROS generation, and suppressing the PERK-eIF2a-CHOP pathway in HaCaT cells
- (2015) Feng Zhong et al. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
- IRE1α-Dependent Decay of CReP/Ppp1r15b mRNA Increases Eukaryotic Initiation Factor 2α Phosphorylation and Suppresses Protein Synthesis
- (2015) Jae-Seon So et al. MOLECULAR AND CELLULAR BIOLOGY
- The balance between adaptive and apoptotic unfolded protein responses regulates β-cell death under ER stress conditions through XBP1, CHOP and JNK
- (2015) Jeng Yie Chan et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Biogenesis of reactive sulfur species for signaling by hydrogen sulfide oxidation pathways
- (2015) Tatiana V Mishanina et al. Nature Chemical Biology
- The transcription factor XBP1 is selectively required for eosinophil differentiation
- (2015) Sarah E Bettigole et al. NATURE IMMUNOLOGY
- S-Nitrosylation links obesity-associated inflammation to endoplasmic reticulum dysfunction
- (2015) L. Yang et al. SCIENCE
- IRE1 prevents endoplasmic reticulum membrane permeabilization and cell death under pathological conditions
- (2015) Kohsuke Kanekura et al. Science Signaling
- Targeting the IRE1α–XBP1 branch of the unfolded protein response in human diseases
- (2015) Dadi Jiang et al. SEMINARS IN CANCER BIOLOGY
- MiR-17 Downregulation by High Glucose Stabilizes Thioredoxin-Interacting Protein and Removes Thioredoxin Inhibition on ASK1 Leading to Apoptosis
- (2015) Daoyin Dong et al. TOXICOLOGICAL SCIENCES
- Innate immunity at mucosal surfaces: the IRE1-RIDD-RIG-I pathway
- (2015) Wayne I. Lencer et al. TRENDS IN IMMUNOLOGY
- The Endoplasmic Reticulum Stress Sensor Inositol-Requiring Enzyme 1α Augments Bacterial Killing through Sustained Oxidant Production
- (2015) Basel H. Abuaita et al. mBio
- IRE1–RACK1 axis orchestrates ER stress preconditioning-elicited cytoprotection from ischemia/reperfusion injury in liver
- (2015) Dong Liu et al. Journal of Molecular Cell Biology
- Erratum: RIPK1 promotes death receptor-independent caspase-8-mediated apoptosis under unresolved ER stress conditions
- (2015) Y Estornes et al. Cell Death & Disease
- A novel chemical, STF-083010, reverses tamoxifen-related drug resistance in breast cancer by inhibiting IRE1/XBP1
- (2015) Jie Ming et al. Oncotarget
- PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response
- (2015) Ananya Gupta et al. Scientific Reports
- The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of β Cells
- (2015) Justin R. Hassler et al. PLOS BIOLOGY
- A functional link between the co-translational protein translocation pathway and the UPR
- (2015) Rachel Plumb et al. eLife
- The unfolded protein response is required for dendrite morphogenesis
- (2015) Xing Wei et al. eLife
- Noncanonical binding of BiP ATPase domain to Ire1 and Perk is dissociated by unfolded protein CH1 to initiate ER stress signaling
- (2015) Marta Carrara et al. eLife
- IRE1 prevents endoplasmic reticulum membrane permeabilization and cell death under pathological conditions
- (2015) Kohsuke Kanekura et al. Science Signaling
- Selective inhibition of unfolded protein response induces apoptosis in pancreatic cancer cells
- (2015) Wenwen Chien et al. Oncotarget
- Endoplasmic reticulum stress associated responses in cancer
- (2014) Wen-An Wang et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Allosteric Inhibition of the IRE1α RNase Preserves Cell Viability and Function during Endoplasmic Reticulum Stress
- (2014) Rajarshi Ghosh et al. CELL
- The IRE1α-XBP1 pathway regulates metabolic stress-induced compensatory proliferation of pancreatic β-cells
- (2014) Tongfu Xu et al. CELL RESEARCH
- Regulation of chondrocyte differentiation by IRE1α depends on its enzymatic activity
- (2014) Feng-Jin Guo et al. CELLULAR SIGNALLING
- Ask1Gene Deletion Blocks Maternal Diabetes–Induced Endoplasmic Reticulum Stress in the Developing Embryo by Disrupting the Unfolded Protein Response Signalosome
- (2014) Fang Wang et al. DIABETES
- The mammalian tRNA ligase complex mediates splicing ofXBP1mRNA and controls antibody secretion in plasma cells
- (2014) Jennifer Jurkin et al. EMBO JOURNAL
- A Combined “Omics” Approach Identifies N-Myc Interactor as a Novel Cytokine-induced Regulator of IRE1α Protein and c-Jun N-terminal Kinase in Pancreatic Beta Cells
- (2014) Flora Brozzi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Fibroblast Growth Factor 21 Is Regulated by the IRE1α-XBP1 Branch of the Unfolded Protein Response and Counteracts Endoplasmic Reticulum Stress-induced Hepatic Steatosis
- (2014) Shan Jiang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Transcriptome analysis of human adipocytes implicates the NOD-like receptor pathway in obesity-induced adipose inflammation
- (2014) Zheng Yin et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- A Synthetic Biology Approach Identifies the Mammalian UPR RNA Ligase RtcB
- (2014) Yanyan Lu et al. MOLECULAR CELL
- Protein Disulfide Isomerase A6 Controls the Decay of IRE1α Signaling via Disulfide-Dependent Association
- (2014) Davide Eletto et al. MOLECULAR CELL
- Endoplasmic reticulum stress preconditioning antagonizes low-density lipoprotein-induced inflammation in human mesangial cells through upregulation of XBP1 and suppression of the IRE1α/IKK/NF-κB pathway
- (2014) YUAN YU et al. Molecular Medicine Reports
- Analysis of orthologous groups reveals archease and DDX1 as tRNA splicing factors
- (2014) Johannes Popow et al. NATURE
- A tRNA splicing operon: Archease endows RtcB with dual GTP/ATP cofactor specificity and accelerates RNA ligation
- (2014) Kevin K. Desai et al. NUCLEIC ACIDS RESEARCH
- Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis
- (2014) M. Lu et al. SCIENCE
- Getting RIDD of RNA: IRE1 in cell fate regulation
- (2014) M. Maurel et al. TRENDS IN BIOCHEMICAL SCIENCES
- JNK interaction with Sab mediates ER stress induced inhibition of mitochondrial respiration and cell death
- (2014) S Win et al. Cell Death & Disease
- Reduced IRE1α mediates apoptotic cell death by disrupting calcium homeostasis via the InsP3 receptor
- (2014) S M Son et al. Cell Death & Disease
- Cab45S inhibits the ER stress-induced IRE1-JNK pathway and apoptosis via GRP78/BiP
- (2014) L Chen et al. Cell Death & Disease
- Phosphoregulation of Ire1 RNase splicing activity
- (2014) Filippo Prischi et al. Nature Communications
- Integration of UPRER and Oxidative Stress Signaling in the Control of Intestinal Stem Cell Proliferation
- (2014) Lifen Wang et al. PLoS Genetics
- ATF6 upregulates XBP1S and inhibits ER stress-mediated apoptosis in osteoarthritis cartilage
- (2013) Feng-Jin Guo et al. CELLULAR SIGNALLING
- ER stress signalling through eIF2α and CHOP, but not IRE1α, attenuates adipogenesis in mice
- (2013) J. Han et al. DIABETOLOGIA
- BiP-bound and nonclustered mode of Ire1 evokes a weak but sustained unfolded protein response
- (2013) Yuki Ishiwata-Kimata et al. GENES TO CELLS
- RNF13, a RING Finger Protein, Mediates Endoplasmic Reticulum Stress-induced Apoptosis through the Inositol-requiring Enzyme (IRE1α)/c-Jun NH2-terminal Kinase Pathway
- (2013) Muhammad Arshad et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulated IRE1-dependent decay pathway is activated during Japanese encephalitis virus-induced unfolded protein response and benefits viral replication
- (2013) S. Bhattacharyya et al. JOURNAL OF GENERAL VIROLOGY
- ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death
- (2013) Jaeseok Han et al. NATURE CELL BIOLOGY
- Suppression of XBP1S Mediates High Glucose-Induced Oxidative Stress and Extracellular Matrix Synthesis in Renal Mesangial Cell and Kidney of Diabetic Rats
- (2013) Decui Shao et al. PLoS One
- Sigma-1 Receptor Chaperone at the ER-Mitochondrion Interface Mediates the Mitochondrion-ER-Nucleus Signaling for Cellular Survival
- (2013) Tomohisa Mori et al. PLoS One
- Negative feedback by IRE1 optimizes mucin production in goblet cells
- (2013) A. Tsuru et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inositol-requiring enzyme 1α is required for gut development inXenopus laviesembryos
- (2013) Jing Guo WORLD JOURNAL OF GASTROENTEROLOGY
- Critical role of anti-apoptotic Bcl-2 protein phosphorylation in mitotic death
- (2013) J M Eichhorn et al. Cell Death & Disease
- Xbp1-Independent Ire1 Signaling Is Required for Photoreceptor Differentiation and Rhabdomere Morphogenesis in Drosophila
- (2013) Dina S. Coelho et al. Cell Reports
- The Role of Adipocyte XBP1 in Metabolic Regulation during Lactation
- (2013) Margaret F. Gregor et al. Cell Reports
- S-Nitrosylation: Specificity, Occupancy, and Interaction with Other Post-Translational Modifications
- (2012) Alicia M. Evangelista et al. ANTIOXIDANTS & REDOX SIGNALING
- Silencing of Lipid Metabolism Genes through IRE1α-Mediated mRNA Decay Lowers Plasma Lipids in Mice
- (2012) Jae-Seon So et al. Cell Metabolism
- IRE1α Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress
- (2012) Alana G. Lerner et al. Cell Metabolism
- Increased Intestinal Lipid Absorption Caused by Ire1β Deficiency Contributes to Hyperlipidemia and Atherosclerosis in Apolipoprotein E–Deficient Mice
- (2012) Jahangir Iqbal et al. CIRCULATION RESEARCH
- Nonmuscle Myosin IIB Links Cytoskeleton to IRE1α Signaling during ER Stress
- (2012) Yin He et al. DEVELOPMENTAL CELL
- BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α
- (2012) Diego A Rodriguez et al. EMBO JOURNAL
- Glucose-dependent insulinotropic peptide impairs insulin signaling via inducing adipocyte inflammation in glucose-dependent insulinotropic peptide receptor-overexpressing adipocytes
- (2012) Yaohui Nie et al. FASEB JOURNAL
- The IRE1α-XBP1 Pathway Positively Regulates Parathyroid Hormone (PTH)/PTH-related Peptide Receptor Expression and Is Involved in PTH-induced Osteoclastogenesis
- (2012) Takahide Tohmonda et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Novel Feedback Loop Regulates the Response to Endoplasmic Reticulum Stress via the Cooperation of Cytoplasmic Splicing and mRNA Translation
- (2012) M. Majumder et al. MOLECULAR AND CELLULAR BIOLOGY
- The ER stress transducer IRE1β is required for airway epithelial mucin production
- (2012) M B Martino et al. Mucosal Immunology
- PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein response
- (2012) Miri Jwa et al. NATURE CELL BIOLOGY
- Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors
- (2012) Likun Wang et al. Nature Chemical Biology
- The unfolded protein response: controlling cell fate decisions under ER stress and beyond
- (2012) Claudio Hetz NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Direct Association of Unfolded Proteins with Mammalian ER Stress Sensor, IRE1β
- (2012) Daisuke Oikawa et al. PLoS One
- Therapeutic targets in the ASK1-dependent stress signaling pathways
- (2012) Ryoichi HAYAKAWA et al. PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES
- IRE1 Cleaves Select microRNAs During ER Stress to Derepress Translation of Proapoptotic Caspase-2
- (2012) J.-P. Upton et al. SCIENCE
- Inflammatory Mechanisms in Obesity
- (2011) Margaret F. Gregor et al. Annual Review of Immunology
- Cofactor-mediated conformational control in the bifunctional kinase/RNase Ire1
- (2011) Alexei V Korennykh et al. BMC BIOLOGY
- mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1–JNK pathway
- (2011) H Kato et al. CELL DEATH AND DIFFERENTIATION
- The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis
- (2011) Kezhong Zhang et al. EMBO JOURNAL
- The IRE1α–XBP1 pathway is essential for osteoblast differentiation through promoting transcription of Osterix
- (2011) Takahide Tohmonda et al. EMBO REPORTS
- Elimination of the NLRP3-ASC Inflammasome Protects against Chronic Obesity-Induced Pancreatic Damage
- (2011) Yun-Hee Youm et al. ENDOCRINOLOGY
- Cdc37/Hsp90 Protein-mediated Regulation of IRE1α Protein Activity in Endoplasmic Reticulum Stress Response and Insulin Synthesis in INS-1 Cells
- (2011) Asuka Ota et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- c-Jun N-terminal Kinase (JNK)-dependent Acute Liver Injury from Acetaminophen or Tumor Necrosis Factor (TNF) Requires Mitochondrial Sab Protein Expression in Mice
- (2011) Sanda Win et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dissociation of Inositol-requiring Enzyme (IRE1α)-mediated c-Jun N-terminal Kinase Activation from Hepatic Insulin Resistance in Conditional X-box-binding Protein-1 (XBP1) Knock-out Mice
- (2011) Michael J. Jurczak et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Membrane aberrancy and unfolded proteins activate the endoplasmic reticulum stress sensor Ire1 in different ways
- (2011) Thanyarat Promlek et al. MOLECULAR BIOLOGY OF THE CELL
- Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling
- (2011) Haitao Wen et al. NATURE IMMUNOLOGY
- The Unfolded Protein Response: Integrating Stress Signals Through the Stress Sensor IRE1α
- (2011) Claudio Hetz et al. PHYSIOLOGICAL REVIEWS
- Dual and opposing roles of the unfolded protein response regulated by IRE1 and XBP1 in proinsulin processing and insulin secretion
- (2011) A.-H. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Unfolded Proteins Are Ire1-Activating Ligands That Directly Induce the Unfolded Protein Response
- (2011) B. M. Gardner et al. SCIENCE
- Modulating stress responses by the UPRosome: A matter of life and death
- (2011) Ute Woehlbier et al. TRENDS IN BIOCHEMICAL SCIENCES
- Anti-apoptotic function of Xbp1 as an IL-3 signaling molecule in hematopoietic cells
- (2011) M Kurata et al. Cell Death & Disease
- Arabidopsis IRE1 catalyses unconventional splicing of bZIP60 mRNA to produce the active transcription factor
- (2011) Yukihiro Nagashima et al. Scientific Reports
- Physiological IRE-1-XBP-1 and PEK-1 Signaling in Caenorhabditis elegans Larval Development and Immunity
- (2011) Claire E. Richardson et al. PLoS Genetics
- Macrophages, Inflammation, and Insulin Resistance
- (2010) Jerrold M. Olefsky et al. Annual Review of Physiology
- Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
- (2010) Gökhan S. Hotamisligil CELL
- Sustained production of spliced X-box binding protein 1 (XBP1) induces pancreatic beta cell dysfunction and apoptosis
- (2010) F. Allagnat et al. DIABETOLOGIA
- Adaptive Unfolded Protein Response Attenuates Alcohol-Induced Pancreatic Damage
- (2010) Aurelia Lugea et al. GASTROENTEROLOGY
- Regulation of basal cellular physiology by the homeostatic unfolded protein response
- (2010) D. Thomas Rutkowski et al. JOURNAL OF CELL BIOLOGY
- Flavonol Activation Defines an Unanticipated Ligand-Binding Site in the Kinase-RNase Domain of IRE1
- (2010) R. Luke Wiseman et al. MOLECULAR CELL
- TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages
- (2010) Fabio Martinon et al. NATURE IMMUNOLOGY
- The regulatory subunits of PI3K, p85α and p85β, interact with XBP-1 and increase its nuclear translocation
- (2010) Sang Won Park et al. NATURE MEDICINE
- Modeling the endoplasmic reticulum unfolded protein response
- (2010) Amos Onn et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- IRE1α Disruption Causes Histological Abnormality of Exocrine Tissues, Increase of Blood Glucose Level, and Decrease of Serum Immunoglobulin Level
- (2010) Takao Iwawaki et al. PLoS One
- Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering
- (2010) H. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Crucial Role for RACK1 in the Regulation of Glucose-Stimulated IRE1 Activation in Pancreatic Cells
- (2010) Y. Qiu et al. Science Signaling
- Toll-like receptors: linking inflammation to metabolism
- (2010) A. Christine Könner et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- BiP Binding to the ER-Stress Sensor Ire1 Tunes the Homeostatic Behavior of the Unfolded Protein Response
- (2010) David Pincus et al. PLOS BIOLOGY
- HSP72 Protects Cells from ER Stress-induced Apoptosis via Enhancement of IRE1α-XBP1 Signaling through a Physical Interaction
- (2010) Sanjeev Gupta et al. PLOS BIOLOGY
- Mechanisms and Implications of Reactive Oxygen Species Generation During the Unfolded Protein Response: Roles of Endoplasmic Reticulum Oxidoreductases, Mitochondrial Electron Transport, and NADPH Oxidase
- (2009) Célio X.C. Santos et al. ANTIOXIDANTS & REDOX SIGNALING
- NR2F1 and IRE1β Suppress Microsomal Triglyceride Transfer Protein Expression and Lipoprotein Assembly in Undifferentiated Intestinal Epithelial Cells
- (2009) Kezhi Dai et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- The Protein Kinase IKKɛ Regulates Energy Balance in Obese Mice
- (2009) Shian-Huey Chiang et al. CELL
- IRE1α Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates
- (2009) Dan Han et al. CELL
- The IRE1α-XBP1 Pathway of the Unfolded Protein Response Is Required for Adipogenesis
- (2009) Haibo Sha et al. Cell Metabolism
- IRE1α controls cyclin A1 expression and promotes cell proliferation through XBP-1
- (2009) Jeffery A. Thorpe et al. CELL STRESS & CHAPERONES
- Activation of mammalian IRE1α upon ER stress depends on dissociation of BiP rather than on direct interaction with unfolded proteins
- (2009) Daisuke Oikawa et al. EXPERIMENTAL CELL RESEARCH
- Airway Epithelial Inflammation-induced Endoplasmic Reticulum Ca2+Store Expansion Is Mediated by X-box Binding Protein-1
- (2009) Mary E. B. Martino et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulated Ire1-dependent decay of messenger RNAs in mammalian cells
- (2009) Julie Hollien et al. JOURNAL OF CELL BIOLOGY
- Unconventional splicing of XBP1 mRNA occurs in the cytoplasm during the mammalian unfolded protein response
- (2009) A. Uemura et al. JOURNAL OF CELL SCIENCE
- GRP78 expression inhibits insulin and ER stress–induced SREBP-1c activation and reduces hepatic steatosis in mice
- (2009) Hélène L. Kammoun et al. JOURNAL OF CLINICAL INVESTIGATION
- BAX Inhibitor-1 Is a Negative Regulator of the ER Stress Sensor IRE1α
- (2009) Fernanda Lisbona et al. MOLECULAR CELL
- CIB1 functions as a Ca2+-sensitive modulator of stress-induced signaling by targeting ASK1
- (2009) K. W. Yoon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability
- (2009) T. Iwawaki et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- How mitochondria produce reactive oxygen species
- (2008) Michael P. Murphy BIOCHEMICAL JOURNAL
- IRE1β Inhibits Chylomicron Production by Selectively Degrading MTP mRNA
- (2008) Jahangir Iqbal et al. Cell Metabolism
- Elevated Toll-Like Receptor 4 Expression and Signaling in Muscle From Insulin-Resistant Subjects
- (2008) S. M. Reyna et al. DIABETES
- Protein quality control in the early secretory pathway
- (2008) Tiziana Anelli et al. EMBO JOURNAL
- Synoviolin promotes IRE1 ubiquitination and degradation in synovial fibroblasts from mice with collagen-induced arthritis
- (2008) Beixue Gao et al. EMBO REPORTS
- RNase domains determine the functional difference between IRE1α and IRE1β
- (2008) Yusuke Imagawa et al. FEBS LETTERS
- AIP1 Is Critical in Transducing IRE1-mediated Endoplasmic Reticulum Stress Response
- (2008) Dianhong Luo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Sweet taste receptor interacting protein CIB1 is a general inhibitor of InsP3-dependent Ca2+releasein vivo
- (2008) Jan K. Hennigs et al. JOURNAL OF NEUROCHEMISTRY
- IRE1β is required for mesoderm formation in Xenopus embryos
- (2008) Li Yuan et al. MECHANISMS OF DEVELOPMENT
- Caspase-2 Cleavage of BID Is a Critical Apoptotic Signal Downstream of Endoplasmic Reticulum Stress
- (2008) J.-P. Upton et al. MOLECULAR AND CELLULAR BIOLOGY
- JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy
- (2008) Yongjie Wei et al. MOLECULAR CELL
- The unfolded protein response signals through high-order assembly of Ire1
- (2008) Alexei V. Korennykh et al. NATURE
- Regulation of Hepatic Lipogenesis by the Transcription Factor XBP1
- (2008) A.-H. Lee et al. SCIENCE
- A kinase inhibitor activates the IRE1α RNase to confer cytoprotection against ER stress
- (2007) Dan Han et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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