Wee1 Inhibition Enhances the Anti-Tumor Effects of Capecitabine in Preclinical Models of Triple-Negative Breast Cancer
出版年份 2020 全文链接
标题
Wee1 Inhibition Enhances the Anti-Tumor Effects of Capecitabine in Preclinical Models of Triple-Negative Breast Cancer
作者
关键词
-
出版物
Cancers
Volume 12, Issue 3, Pages 719
出版商
MDPI AG
发表日期
2020-03-19
DOI
10.3390/cancers12030719
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Combined Aurora kinase A (AURKA) and WEE1 inhibition demonstrates synergistic antitumor effect in squamous cell carcinoma of the head and neck
- (2019) Jong Woo Lee et al. CLINICAL CANCER RESEARCH
- The contribution of DNA replication stress marked by high-intensity, pan-nuclear γH2AX staining to chemosensitization by CHK1 and WEE1 inhibitors
- (2018) Leslie A. Parsels et al. CELL CYCLE
- The combination of the PARP inhibitor olaparib and the Wee1 inhibitor AZD1775 as a new therapeutic option for small cell lung cancer
- (2018) Alice Lallo et al. CLINICAL CANCER RESEARCH
- Wee1 Inhibitor AZD1775 Combined with Cisplatin Potentiates Anticancer Activity against Gastric Cancer by Increasing DNA Damage and Cell Apoptosis
- (2018) Dongshao Chen et al. Biomed Research International
- Combined Inhibition of ATR and WEE1 as a Novel Therapeutic Strategy in Triple-Negative Breast Cancer
- (2018) Juan Jin et al. NEOPLASIA
- AZD1775 Increases Sensitivity to Olaparib and Gemcitabine in Cancer Cells with p53 Mutations
- (2018) Xiangbing Meng et al. Cancers
- Dual compartmental targeting of cell cycle and angiogenic kinases in colorectal cancer models
- (2018) Anna Capasso et al. ANTI-CANCER DRUGS
- Efficacy and Molecular Mechanisms of Differentiated Response to the Aurora and Angiogenic Kinase Inhibitor ENMD-2076 in Preclinical Models of p53-Mutated Triple-Negative Breast Cancer
- (2017) Anastasia A. Ionkina et al. Frontiers in Oncology
- Phase I Study Evaluating WEE1 Inhibitor AZD1775 As Monotherapy and in Combination With Gemcitabine, Cisplatin, or Carboplatin in Patients With Advanced Solid Tumors
- (2016) Suzanne Leijen et al. JOURNAL OF CLINICAL ONCOLOGY
- Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies
- (2016) Stacey Bagby et al. Jove-Journal of Visualized Experiments
- Inhibiting WEE1 Selectively Kills Histone H3K36me3-Deficient Cancers by dNTP Starvation
- (2015) Sophia X. Pfister et al. CANCER CELL
- The Efficacy of the Wee1 Inhibitor MK-1775 Combined with Temozolomide Is Limited by Heterogeneous Distribution across the Blood-Brain Barrier in Glioblastoma
- (2015) J. L. Pokorny et al. CLINICAL CANCER RESEARCH
- Comparative Effectiveness Analysis of Monotherapy With Cytotoxic Agents in Triple-negative Metastatic Breast Cancer in a Community Setting
- (2015) George Dranitsaris et al. CLINICAL THERAPEUTICS
- Phase I Study of Single-Agent AZD1775 (MK-1775), a Wee1 Kinase Inhibitor, in Patients With Refractory Solid Tumors
- (2015) Khanh Do et al. JOURNAL OF CLINICAL ONCOLOGY
- Phase III Open-Label Randomized Study of Eribulin Mesylate Versus Capecitabine in Patients With Locally Advanced or Metastatic Breast Cancer Previously Treated With an Anthracycline and a Taxane
- (2015) Peter A. Kaufman et al. JOURNAL OF CLINICAL ONCOLOGY
- p53 Family Members Regulate Phenotypic Response to Aurora Kinase A Inhibition in Triple-Negative Breast Cancer
- (2015) J. J. Tentler et al. MOLECULAR CANCER THERAPEUTICS
- Functional Genetic Screen Identifies Increased Sensitivity to WEE1 Inhibition in Cells with Defects in Fanconi Anemia and HR Pathways
- (2015) M. Aarts et al. MOLECULAR CANCER THERAPEUTICS
- Comprehensive Genomic Analysis Identifies Novel Subtypes and Targets of Triple-Negative Breast Cancer
- (2014) M. D. Burstein et al. CLINICAL CANCER RESEARCH
- Capecitabine and lapatinib uptake in surgically resected brain metastases from metastatic breast cancer patients: a prospective study
- (2014) Aki Morikawa et al. NEURO-ONCOLOGY
- Efficient Induction of Apoptosis by Wee1 Kinase Inhibition in Hepatocellular Carcinoma Cells
- (2014) Tomomi Kogiso et al. PLoS One
- Tumour selective targeting of cell cycle kinases for cancer treatment
- (2013) Marieke Aarts et al. CURRENT OPINION IN PHARMACOLOGY
- Establishment of a 5-fluorouracil-resistant triple-negative breast cancer cell line
- (2013) KATSUYUKI TAKAHASHI et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Mutational landscape and significance across 12 major cancer types
- (2013) Cyriac Kandoth et al. NATURE
- MK-1775, a small molecule Wee1 inhibitor, enhances anti-tumor efficacy of various DNA-damaging agents, including 5-fluorouracil
- (2010) Hiroshi Hirai et al. CANCER BIOLOGY & THERAPY
- Evolution of Capecitabine Dosing in Breast Cancer
- (2010) Michael Naughton Clinical Breast Cancer
- Biology, Metastatic Patterns, and Treatment of Patients with Triple-Negative Breast Cancer
- (2009) Carey K. Anders et al. Clinical Breast Cancer
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started