Radical C–H functionalization to construct heterocyclic compounds

Copper-Catalyzed Aryltrifluoromethylation ofN-Phenylcinnamamides: Access to Trifluoromethylated 3,4-Dihydroquinolin-2(1 H)-ones

(2015) Qiang Wang et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis of Quinolines by Visible-Light Induced Radical Reaction of Vinyl Azides and α-Carbonyl Benzyl Bromides

(2015) Qile Wang et al.   ADVANCED SYNTHESIS & CATALYSIS

Visible-Light-Promoted Iminyl-Radical Formation from Acyl Oximes: A Unified Approach to Pyridines, Quinolines, and Phenanthridines

(2015) Heng Jiang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metal-free nitrative cyclization of N-aryl imines with tert-butyl nitrite: dehydrogenative access to 3-nitroindoles

(2015) Guo-Bo Deng et al.   CHEMICAL COMMUNICATIONS

Direct and metal-free arylsulfonylation of alkynes with sulfonylhydrazides for the construction of 3-sulfonated coumarins

(2015) Wei Wei et al.   CHEMICAL COMMUNICATIONS

Visible-light initiated oxidative cyclization of phenyl propiolates with sulfinic acids to coumarin derivatives under metal-free conditions

(2015) Wenchao Yang et al.   CHEMICAL COMMUNICATIONS

Tuning radical reactivity using iodine in oxidative C(sp3)–H/C(sp)–H cross-coupling: an easy way toward the synthesis of furans and indolizines

(2015) Shan Tang et al.   CHEMICAL COMMUNICATIONS

Stereoselective synthesis of vinylphosphonates and phosphine oxides via silver-catalyzed phosphorylation of styrenes

(2015) Qingwen Gui et al.   CHEMICAL COMMUNICATIONS

Transition-Metal-Catalyzed Direct Addition of Unactivated C–H Bonds to Polar Unsaturated Bonds

(2015) Lei Yang et al.   CHEMICAL REVIEWS

Metal-mediated post-Ugi transformations for the construction of diverse heterocyclic scaffolds

(2015) Upendra K. Sharma et al.   CHEMICAL SOCIETY REVIEWS

Recent advances in the synthesis of nitrogen heterocycles via radical cascade reactions using isonitriles as radical acceptors

(2015) Bo Zhang et al.   CHEMICAL SOCIETY REVIEWS

Electrochemical Intramolecular CH Amination: Synthesis of Benzoxazoles and Benzothiazoles

(2015) Tatsuya Morofuji et al.   CHEMISTRY-A EUROPEAN JOURNAL

Recent Advances in Inert Bonds Activation with Isocyanides

(2015) Hao Wang et al.   CHINESE JOURNAL OF ORGANIC CHEMISTRY

Syntheses of Arnottin I and Arnottin II

(2015) Matthew J. Moschitto et al.   JOURNAL OF ORGANIC CHEMISTRY

Silver-Mediated Radical Cyclization of Alkynoates and α-Keto Acids Leading to Coumarins via Cascade Double C–C Bond Formation

(2015) Kelu Yan et al.   JOURNAL OF ORGANIC CHEMISTRY

Visible-Light-Mediated Radical Aryldifluoroacetylation of Alkynes with Ethyl Bromodifluoroacetate for the Synthesis of 3-Difluoroacetylated Coumarins

(2015) Weijun Fu et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed, Ring-Forming Aromatic C–H Alkylations with Unactivated Alkyl Halides

(2015) Alexander R. O. Venning et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

External Oxidant-Free Oxidative Cross-Coupling: A Photoredox Cobalt-Catalyzed Aromatic C–H Thiolation for Constructing C–S Bonds

(2015) Guoting Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diethylene Glycol Serving as Ethyne Equivalent: A Sustainable Approach toward 2,3-Disubstituted Furan

(2015) Jin-Tao Yu et al.   ORGANIC LETTERS

Copper(I)-Catalyzed Radical Addition of Acetophenones to Alkynes in Furan Synthesis

(2015) Srimanta Manna et al.   ORGANIC LETTERS

Visible-Light Induced Trifluoromethylation of N-Arylcinnamamides for the Synthesis of CF3-Containing 3,4-Disubstituted Dihydroquinolinones and 1-Azaspiro[4.5]decanes

(2015) Fei Gao et al.   ORGANIC LETTERS

Photocatalytic Dehydrogenative Lactonization of 2-Arylbenzoic Acids

(2015) Nieves P. Ramirez et al.   ORGANIC LETTERS

A novel direct synthesis of 3-acyl-4-aryldihydroquinolin-2(1H)-ones via metal-free radical tandem cyclization between N-arylcinnamamides and aldehydes

(2015) Wen-Peng Mai et al.   TETRAHEDRON

Radical 5-exo cyclization of alkynoates with 2-oxoacetic acids for synthesis of 3-acylcoumarins

(2015) Tong Liu et al.   Organic Chemistry Frontiers

Synthesis of silafluorenes and silaindenes via silyl radicals from arylhydrosilanes: intramolecular cyclization and intermolecular annulation with alkynes

(2015) Liang Xu et al.   Organic Chemistry Frontiers

Direct radical trifluoromethylthiolation and thiocyanation of aryl alkynoate esters: mild and facile synthesis of 3-trifluoromethylthiolated and 3-thiocyanated coumarins

(2015) Yao-Fu Zeng et al.   Organic Chemistry Frontiers

Progress in Synthesis of Oxindoles by Radical Addition-Cyclization

(2015) Wenpeng Mai et al.   CHINESE JOURNAL OF ORGANIC CHEMISTRY

The [3 + 3]-Cycloaddition Alternative for Heterocycle Syntheses: Catalytically Generated Metalloenolcarbenes as Dipolar Adducts

(2014) Xinfang Xu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Regiospecific Synthesis of 1-Trifluoromethylisoquinolines Enabled by Photoredox Somophilic Vinyl Isocyanide Insertion

(2014) Yuanzheng Cheng et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis of Highly Functionalized Polycyclic Quinoxaline Derivatives Using Visible-Light Photoredox Catalysis

(2014) Zhi He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dehydrogenative N-Incorporation: A Direct Approach to QuinoxalineN-Oxides under Mild Conditions

(2014) Feng Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mild ArI-Catalyzed C(sp2)H or C(sp3)H Functionalization/CO Formation: An Intriguing Catalyst-Controlled Selectivity Switch

(2014) Xueqiang Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Gold-Catalyzed C(sp3)H/C(sp)H Coupling/Cyclization/Oxidative Alkynylation Sequence: A Powerful Strategy for the Synthesis of 3-Alkynyl Polysubstituted Furans

(2014) Yuanhong Ma et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of isoquinolines via visible light-promoted insertion of vinyl isocyanides with diaryliodonium salts

(2014) Heng Jiang et al.   CHEMICAL COMMUNICATIONS

Copper-catalyzed tandem oxidative cyclization of cinnamamides with benzyl hydrocarbons through cross-dehydrogenative coupling

(2014) Shi-Liu Zhou et al.   CHEMICAL COMMUNICATIONS

Gold-catalyzed C(sp3)–H bond functionalization

(2014) Jin Xie et al.   CHEMICAL SOCIETY REVIEWS

Silver-Catalyzed C(sp2)–H Functionalization/C–O Cyclization Reaction at Room Temperature

(2014) Jian-Jun Dai et al.   JOURNAL OF ORGANIC CHEMISTRY

Silver-Catalyzed Radical Tandem Cyclization: An Approach to Direct Synthesis of 3-Acyl-4-arylquinolin-2(1H)-ones

(2014) Wen-Peng Mai et al.   JOURNAL OF ORGANIC CHEMISTRY

Preparation of 3-Acyl-4-arylcoumarins via Metal-Free Tandem Oxidative Acylation/Cyclization between Alkynoates with Aldehydes

(2014) Xia Mi et al.   JOURNAL OF ORGANIC CHEMISTRY

1-Trifluoromethylated isoquinolines via radical trifluoromethylation of isonitriles

(2014) Bo Zhang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

9-Silafluorenes via Base-Promoted Homolytic Aromatic Substitution (BHAS) – The Electron as a Catalyst

(2014) Dirk Leifert et al.   ORGANIC LETTERS

Silver-Catalyzed Synthesis of 3-Phosphorated Coumarins via Radical Cyclization of Alkynoates and Dialkyl H-Phosphonates

(2014) Xia Mi et al.   ORGANIC LETTERS

Direct Oxidative Coupling of Enamides and 1,3-Dicarbonyl Compounds: A Facile and Versatile Approach to Dihydrofurans, Furans, Pyrroles, and Dicarbonyl Enamides

(2014) Pan Li et al.   ORGANIC LETTERS

Copper-Catalyzed Direct Trifluoromethylation of Propiolates: Construction of Trifluoromethylated Coumarins

(2014) Yuewen Li et al.   ORGANIC LETTERS

Silver-catalyzed tandem radical acylarylation of cinnamamides in aqueous media

(2014) Hua Yang et al.   RSC Advances

Metal-Free Oxidative Coupling: Xanthone FormationviaDirect Annulation of 2-Aryloxybenzaldehyde using Tetrabutylammonium Bromide as a Promoter in Aqueous Medium

(2013) Honghua Rao et al.   ADVANCED SYNTHESIS & CATALYSIS

Iron-Catalyzed Oxidative Radical Cross-Coupling/Cyclization between Phenols and Olefins

(2013) Zhiliang Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Indole Synthesis by Rhodium(III)-Catalyzed Hydrazine-Directed CH Activation: Redox-Neutral and Traceless by NN Bond Cleavage

(2013) Dongbing Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct Annulations toward Phosphorylated Oxindoles: Silver-Catalyzed Carbon-Phosphorus Functionalization of Alkenes

(2013) Ya-Min Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

General and Practical Carboxyl-Group-Directed Remote CH Oxygenation Reactions of Arenes

(2013) Yang Wang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Visible-Light-Induced Radical Cyclization of Trifluoroacetimidoyl Chlorides with Alkynes: Catalytic Synthesis of 2-Trifluoromethyl Quinolines

(2013) Xichang Dong et al.   CHEMISTRY-A EUROPEAN JOURNAL

Silver-Mediated Oxidative C–H/P–H Functionalization: An Efficient Route for the Synthesis of Benzo[b]phosphole Oxides

(2013) Yun-Rong Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cu-Catalyzed Mild C(sp2)–H Functionalization Assisted by Carboxylic Acids en Route to Hydroxylated Arenes

(2013) Joan Gallardo-Donaire et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cross Dehydrogenative Coupling via Base-Promoted Homolytic Aromatic Substitution (BHAS): Synthesis of Fluorenones and Xanthones

(2013) Sebastian Wertz et al.   ORGANIC LETTERS

Silver-Catalyzed Radical Tandem Cyclization for the Synthesis of 3,4-Disubstituted Dihydroquinolin-2(1H)-ones

(2013) Wen-Peng Mai et al.   ORGANIC LETTERS

Modular Synthesis of Phenanthridine Derivatives by Oxidative Cyclization of 2-Isocyanobiphenyls with Organoboron Reagents

(2012) Mamoru Tobisu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Baeyer–Villiger C–C Bond Cleavage Reaction in Gilvocarcin and Jadomycin Biosynthesis

(2012) Nidhi Tibrewal et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silver-Mediated Oxidative C–H/C–H Functionalization: A Strategy To Construct Polysubstituted Furans

(2012) Chuan He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Weak Coordination as a Powerful Means for Developing Broadly Useful C–H Functionalization Reactions

(2011) Keary M. Engle et al.   ACCOUNTS OF CHEMICAL RESEARCH

Preparation of 5-Membered Rings via Radical Addition- Translocation-Cyclization (RATC) Processes Mediated by Diethyl Thiophosphites

(2011) Christophe Lamarque et al.   ADVANCED SYNTHESIS & CATALYSIS

Fe-catalysed oxidative C–H functionalization/C–S bond formation

(2011) Haibo Wang et al.   CHEMICAL COMMUNICATIONS

Design, Synthesis, and Evaluation of Coumarin-Based Molecular Probes for Imaging of Myelination

(2011) Changning Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Aerobic Visible-Light Photoredox Radical C–H Functionalization: Catalytic Synthesis of 2-Substituted Benzothiazoles

(2011) Yannan Cheng et al.   ORGANIC LETTERS

Pd(II)-Catalyzed Hydroxyl-Directed C−H Activation/C−O Cyclization: Expedient Construction of Dihydrobenzofurans

(2010) Xisheng Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium(III)-Catalyzed Arene and Alkene C−H Bond Functionalization Leading to Indoles and Pyrroles

(2010) David R. Stuart et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Indoles from Simple Anilines and Alkynes: Palladium-Catalyzed CH Activation Using Dioxygen as the Oxidant

(2009) Zhuangzhi Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct Phosphonylation of Aromatic Azaheterocycles

(2009) Sarah Van der Jeught et al.   CHEMICAL REVIEWS

Rhodium-Catalyzed C−C Bond Formation via Heteroatom-Directed C−H Bond Activation

(2009) Denise A. Colby et al.   CHEMICAL REVIEWS

2-Arylbenzothiazole as a Privileged Scaffold in Drug Discovery

(2009) A. Weekes et al.   CURRENT MEDICINAL CHEMISTRY

Visible Light-Driven Hydrogen Production from Aqueous Protons Catalyzed by Molecular Cobaloxime Catalysts

(2009) Pingwu Du et al.   INORGANIC CHEMISTRY

Adenosine Receptor Antagonists:  Translating Medicinal Chemistry and Pharmacology into Clinical Utility

(2008) Pier Giovanni Baraldi et al.   CHEMICAL REVIEWS

Phosphorylated Proteins and Control over Apatite Nucleation, Crystal Growth, and Inhibition

(2008) Anne George et al.   CHEMICAL REVIEWS

Intermolecular Radical Addition of Alkylthio- and Arylthiodiphenylphosphines to Terminal Alkynes

(2008) Tatsuya Wada et al.   ORGANIC LETTERS