Brain-specific repression of AMPKα1 alleviates pathophysiology in Alzheimer’s model mice

Genetic reduction of eEF2 kinase alleviates pathophysiology in Alzheimer’s disease model mice

(2019) Brenna C. Beckelman et al.   JOURNAL OF CLINICAL INVESTIGATION

Dementia with Lewy bodies: an update and outlook

(2019) Tiago Fleming Outeiro et al.   Molecular Neurodegeneration

Therapeutic Potential of AMP-Activated Protein Kinase in Alzheimer’s Disease

(2019) Xin Wang et al.   JOURNAL OF ALZHEIMERS DISEASE

Calcium Signaling Deficits in Glia and Autophagic Pathways Contributing to Neurodegenerative Disease

(2018) Sarah Mustaly-Kalimi et al.   ANTIOXIDANTS & REDOX SIGNALING

Genetic Removal of eIF2α Kinase PERK in Mice Enables Hippocampal L-LTP Independent of mTORC1 Activity

(2018) Helena R. Zimmermann et al.   JOURNAL OF NEUROCHEMISTRY

Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums

(2018) Steven E. Arnold et al.   Nature Reviews Neurology

Expanding the Phenotype of Homozygous KCNMA1 Mutations; Dyskinesia, Epilepsy, Intellectual Disability, Cerebellar and Corticospinal Tract Atrophy

(2018) Gözde Yeşil et al.   Balkan Medical Journal

Dementia with Lewy Bodies: Molecular Pathology in the Frontal Cortex in Typical and Rapidly Progressive Forms

(2017) Paula Garcia-Esparcia et al.   Frontiers in Neurology

eEF2K inhibition blocks Aβ42 neurotoxicity by promoting an NRF2 antioxidant response

(2016) Asad Jan et al.   ACTA NEUROPATHOLOGICA

AMPK in Neurodegenerative Diseases: Implications and Therapeutic Perspectives

(2016) Claudia Marinangeli et al.   CURRENT DRUG TARGETS

Molecular neuropathology of frontotemporal dementia: insights into disease mechanisms from postmortem studies

(2016) Ian R. A. Mackenzie et al.   JOURNAL OF NEUROCHEMISTRY

Repression of the eIF2α kinase PERK alleviates mGluR-LTD impairments in a mouse model of Alzheimer's disease

(2016) Wenzhong Yang et al.   NEUROBIOLOGY OF AGING

Evolving Lessons on the Complex Role of AMPK in Normal Physiology and Cancer

(2016) Biplab Dasgupta et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

PERK inhibition prevents tau-mediated neurodegeneration in a mouse model of frontotemporal dementia

(2015) Helois Radford et al.   ACTA NEUROPATHOLOGICA

Regulation and roles of elongation factor 2 kinase

(2015) Christopher G. Proud   BIOCHEMICAL SOCIETY TRANSACTIONS

Co-activation of AMPK and mTORC1 Induces Cytotoxicity in Acute Myeloid Leukemia

(2015) Pierre Sujobert et al.   Cell Reports

AMPK—Sensing Energy while Talking to Other Signaling Pathways

(2014) D. Grahame Hardie   Cell Metabolism

AMPK at the Nexus of Energetics and Aging

(2014) Kristopher Burkewitz et al.   Cell Metabolism

Inhibition of AMP-Activated Protein Kinase Signaling Alleviates Impairments in Hippocampal Synaptic Plasticity Induced by Amyloid  

(2014) T. Ma et al.   JOURNAL OF NEUROSCIENCE

Dendritic Spines: The Locus of Structural and Functional Plasticity

(2014) Carlo Sala et al.   PHYSIOLOGICAL REVIEWS

Rapid Golgi Analysis Method for Efficient and Unbiased Classification of Dendritic Spines

(2014) W. Christopher Risher et al.   PLoS One

PERK: a novel therapeutic target for neurodegenerative diseases?

(2014) Tao Ma et al.   Alzheimers Research & Therapy

Hippocampal metabolomics using ultrahigh-resolution mass spectrometry reveals neuroinflammation from Alzheimer’s disease in CRND8 mice

(2013) Shuhai Lin et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

AMPK activity is regulated by calcium-mediated protein phosphatase 2A activity

(2013) S. Park et al.   CELL CALCIUM

Increased Risk of Cognitive Impairment in Patients With Diabetes Is Associated With Metformin

(2013) E. M. Moore et al.   DIABETES CARE

Suppression of eIF2α kinases alleviates Alzheimer's disease–related plasticity and memory deficits

(2013) Tao Ma et al.   NATURE NEUROSCIENCE

The CAMKK2-AMPK Kinase Pathway Mediates the Synaptotoxic Effects of Aβ Oligomers through Tau Phosphorylation

(2013) Georges Mairet-Coello et al.   NEURON

Sustained translational repression by eIF2α-P mediates prion neurodegeneration

(2012) Julie A. Moreno et al.   NATURE

Roles of AMP-activated Protein Kinase in Alzheimer’s Disease

(2012) Zhiyou Cai et al.   NEUROMOLECULAR MEDICINE

AMP-activated protein kinase (AMPK) is a tau kinase, activated in response to amyloid β-peptide exposure

(2011) Claire Thornton et al.   BIOCHEMICAL JOURNAL

AMP-activated protein kinase--an energy sensor that regulates all aspects of cell function

(2011) D. G. Hardie   GENES & DEVELOPMENT

Amyloid β: linking synaptic plasticity failure to memory disruption in Alzheimer’s disease

(2011) Tao Ma et al.   JOURNAL OF NEUROCHEMISTRY

AMP-activated protein kinase: a potential player in Alzheimer’s disease

(2011) Antero Salminen et al.   JOURNAL OF NEUROCHEMISTRY

Structure of mammalian AMPK and its regulation by ADP

(2011) Bing Xiao et al.   NATURE

Peripheral insulin-sensitizer drug metformin ameliorates neuronal insulin resistance and Alzheimer’s-like changes

(2011) Amit Gupta et al.   NEUROPHARMACOLOGY

Alzheimer's Disease: The Challenge of the Second Century

(2011) D. M. Holtzman et al.   Science Translational Medicine

AMPK is abnormally activated in tangle- and pre-tangle-bearing neurons in Alzheimer’s disease and other tauopathies

(2010) Valérie Vingtdeux et al.   ACTA NEUROPATHOLOGICA

AMPK inhibition in health and disease

(2010) Benoit Viollet et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

SUnSET, a nonradioactive method to monitor protein synthesis

(2009) Enrico K Schmidt et al.   NATURE METHODS

Translational Control of Long-Lasting Synaptic Plasticity and Memory

(2009) Mauro Costa-Mattioli et al.   NEURON

AMPK in Health and Disease

(2009) Gregory R. Steinberg et al.   PHYSIOLOGICAL REVIEWS

Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription

(2009) Y. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BioVenn – a web application for the comparison and visualization of biological lists using area-proportional Venn diagrams

(2008) Tim Hulsen et al.   BMC GENOMICS

Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease

(2008) Ilya Bezprozvanny et al.   TRENDS IN NEUROSCIENCES

The role of protein synthesis during the labile phases of memory: Revisiting the skepticism

(2007) Cristina M. Alberini   NEUROBIOLOGY OF LEARNING AND MEMORY