Sustained translational repression by eIF2α-P mediates prion neurodegeneration

Prion propagation and toxicity in vivo occur in two distinct mechanistic phases

(2011) Malin K. Sandberg et al.   NATURE

Nitric Oxide Is an Activity-Dependent Regulator of Target Neuron Intrinsic Excitability

(2011) Joern R. Steinert et al.   NEURON

Selective Inhibition of a Regulatory Subunit of Protein Phosphatase 1 Restores Proteostasis

(2011) P. Tsaytler et al.   SCIENCE

A Molecular Toolbox for Rapid Generation of Viral Vectors to Up- or Down-Regulate Neuronal Gene Expression in vivo

(2011) Melanie D. White et al.   Frontiers in Molecular Neuroscience

Acute hyperbilirubinaemia induces presynaptic neurodegeneration at a central glutamatergic synapse

(2010) Martin D. Haustein et al.   JOURNAL OF PHYSIOLOGY-LONDON

Flavonol Activation Defines an Unanticipated Ligand-Binding Site in the Kinase-RNase Domain of IRE1

(2010) R. Luke Wiseman et al.   MOLECULAR CELL

Translational Regulation of Gene Expression during Conditions of Cell Stress

(2010) Keith A. Spriggs et al.   MOLECULAR CELL

The Unfolded Protein Response Is Activated in Pretangle Neurons in Alzheimer's Disease Hippocampus

(2009) Jeroen J.M. Hoozemans et al.   AMERICAN JOURNAL OF PATHOLOGY

A role for motoneuron subtype–selective ER stress in disease manifestations of FALS mice

(2009) Smita Saxena et al.   NATURE NEUROSCIENCE

Eif-2a Protects Brainstem Motoneurons in a Murine Model of Sleep Apnea

(2008) Y. Zhu et al.   JOURNAL OF NEUROSCIENCE

Single treatment with RNAi against prion protein rescues early neuronal dysfunction and prolongs survival in mice with prion disease

(2008) M. D. White et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adapting Proteostasis for Disease Intervention

(2008) William E. Balch et al.   SCIENCE