Pathogenesis of peritumoral hyperexcitability in an immunocompetent CRISPR-based glioblastoma model

PIK3CA variants selectively initiate brain hyperactivity during gliomagenesis

(2020) Kwanha Yu et al.   NATURE

Neuron–glia interactions in the pathophysiology of epilepsy

(2019) Dipan C. Patel et al.   NATURE REVIEWS NEUROSCIENCE

Author Correction: Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution

(2019) Takahiro Masuda et al.   NATURE

Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39

(2019) Maisa C. Takenaka et al.   NATURE NEUROSCIENCE

Genetic and molecular epidemiology of adult diffuse glioma

(2019) Annette M. Molinaro et al.   Nature Reviews Neurology

Neuroinflammatory pathways as treatment targets and biomarkers in epilepsy

(2019) Annamaria Vezzani et al.   Nature Reviews Neurology

Tumor-associated reactive astrocytes aid the evolution of immunosuppressive environment in glioblastoma

(2019) Dieter Henrik Heiland et al.   Nature Communications

Brain tumours repurpose endogenous neuron to microglia signalling mechanisms to promote their own proliferation

(2019) Kelda Chia et al.   eLife

Harnessing Microglia and Macrophages for the Treatment of Glioblastoma

(2019) Ioanna Prionisti et al.   Frontiers in Pharmacology

Dynamic Gain Analysis Reveals Encoding Deficiencies in Cortical Neurons That Recover from Hypoxia-Induced Spreading Depolarizations

(2019) Omer Revah et al.   JOURNAL OF NEUROSCIENCE

Electrical and synaptic integration of glioma into neural circuits

(2019) Humsa S. Venkatesh et al.   NATURE

Glutamatergic synaptic input to glioma cells drives brain tumour progression

(2019) Varun Venkataramani et al.   NATURE

Microglia/Brain Macrophages as Central Drivers of Brain Tumor Pathobiology

(2019) David H. Gutmann et al.   NEURON

High expression of cystine–glutamate antiporter xCT (SLC7A11) is an independent biomarker for epileptic seizures at diagnosis in glioma

(2018) Mai Froberg Sørensen et al.   JOURNAL OF NEURO-ONCOLOGY

A glial blueprint for gliomagenesis

(2018) Dylan Laug et al.   NATURE REVIEWS NEUROSCIENCE

An active role for neurons in glioma progression: making sense of Scherer’s structures

(2018) Shawn Gillespie et al.   NEURO-ONCOLOGY

Spreading depolarization is not an epiphenomenon but the principal mechanism of the cytotoxic edema in various gray matter structures of the brain during stroke

(2018) Jens P. Dreier et al.   NEUROPHARMACOLOGY

Asynchronous suppression of visual cortex during absence seizures in stargazer mice

(2018) Jochen Meyer et al.   Nature Communications

The p53 Pathway in Glioblastoma

(2018) Ying Zhang et al.   Cancers

Prevalence of symptoms in glioma patients throughout the disease trajectory: a systematic review

(2018) Margriet IJzerman-Korevaar et al.   JOURNAL OF NEURO-ONCOLOGY

Human microglia regional heterogeneity and phenotypes determined by multiplexed single-cell mass cytometry

(2018) Chotima Böttcher et al.   NATURE NEUROSCIENCE

Neuro-Immune Hemostasis: Homeostasis and Diseases in the Central Nervous System

(2018) Ciro De Luca et al.   Frontiers in Cellular Neuroscience

Perineuronal nets decrease membrane capacitance of peritumoral fast spiking interneurons in a model of epilepsy

(2018) Bhanu P. Tewari et al.   Nature Communications

Exploring the role of microglia in cortical spreading depression in neurological disease

(2017) Mamoru Shibata et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Tumor-related neurocognitive dysfunction in patients with diffuse glioma: a systematic review of neurocognitive functioning prior to anti-tumor treatment

(2017) Emma van Kessel et al.   JOURNAL OF NEURO-ONCOLOGY

Phosphorylation of tau at Y18, but not tau-fyn binding, is required for tau to modulate NMDA receptor-dependent excitotoxicity in primary neuronal culture

(2017) Takashi Miyamoto et al.   Molecular Neurodegeneration

Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma

(2017) Humsa S. Venkatesh et al.   NATURE

Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy

(2017) Xiaoyang Lan et al.   NATURE

Microglia emerge as central players in brain disease

(2017) Michael W Salter et al.   NATURE MEDICINE

Identification of diverse astrocyte populations and their malignant analogs

(2017) Chia-Ching John Lin et al.   NATURE NEUROSCIENCE

PTEN regulates glioblastoma oncogenesis through chromatin-associated complexes of DAXX and histone H3.3

(2017) Jorge A. Benitez et al.   Nature Communications

The Last 10 Days of Patients With Glioblastoma

(2016) Katrin Thier et al.   American Journal of Hospice & Palliative Medicine

Origins of Brain Tumor Macrophages

(2016) Michele De Palma   CANCER CELL

Glioma-mediated microglial activation promotes glioma proliferation and migration: roles of Na+/H+exchanger isoform 1

(2016) Wen Zhu et al.   CARCINOGENESIS

High-mobility group box 1 is an important mediator of microglial activation induced by cortical spreading depression

(2016) Tsubasa Takizawa et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neuronal Activity Promotes Glioma Growth through Neuroligin-3 Secretion

(2015) Humsa S. Venkatesh et al.   CELL

Reactive Astrogliosis Causes the Development of Spontaneous Seizures

(2015) S. Robel et al.   JOURNAL OF NEUROSCIENCE

Pathway-driven discovery of epilepsy genes

(2015) Jeffrey Noebels   NATURE NEUROSCIENCE

SLC7A11 expression is associated with seizures and predicts poor survival in patients with malignant glioma

(2015) Stephanie M. Robert et al.   Science Translational Medicine

Spreading depolarization in the brainstem mediates sudden cardiorespiratory arrest in mouse SUDEP models

(2015) Isamu Aiba et al.   Science Translational Medicine

Tau reduction prevents disease in a mouse model of Dravet syndrome

(2014) Ania L. Gheyara et al.   ANNALS OF NEUROLOGY

GABAergic disinhibition and impaired KCC2 cotransporter activity underlie tumor-associated epilepsy

(2014) Susan L. Campbell et al.   GLIA

Chaos and commotion in the wake of cortical spreading depression and spreading depolarizations

(2014) Daniela Pietrobon et al.   NATURE REVIEWS NEUROSCIENCE

Seizure resistance without parkinsonism in aged mice after tau reduction

(2014) Zhiyong Li et al.   NEUROBIOLOGY OF AGING

The Role of Microglia and Matrix Metalloproteinases Involvement in Neuroinflammation and Gliomas

(2013) Helen Könnecke et al.   Clinical & Developmental Immunology

Spreading depression triggers ictaform activity in partially disinhibited neuronal tissues

(2013) Marius Eickhoff et al.   EXPERIMENTAL NEUROLOGY

Spreading depression features and Iba1 immunoreactivity in the cerebral cortex of developing rats submitted to treadmill exercise after treatment with monosodium glutamate

(2013) Cássia Borges Lima et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Tau Loss Attenuates Neuronal Network Hyperexcitability in Mouse and Drosophila Genetic Models of Epilepsy

(2013) J. K. Holth et al.   JOURNAL OF NEUROSCIENCE

Antisense Reduction of Tau in Adult Mice Protects against Seizures

(2013) S. L. DeVos et al.   JOURNAL OF NEUROSCIENCE

Emergence of a seizure phenotype in aged apolipoprotein epsilon 4 targeted replacement mice

(2012) Jesse M. Hunter et al.   BRAIN RESEARCH

Human glioma cells induce hyperexcitability in cortical networks

(2012) Susan L. Campbell et al.   EPILEPSIA

Sustained NMDA receptor activation by spreading depolarizations can initiate excitotoxic injury in metabolically compromised neurons

(2012) Isamu Aiba et al.   JOURNAL OF PHYSIOLOGY-LONDON

Glutamate is associated with a higher risk of seizures in patients with gliomas

(2012) T. I. Yuen et al.   NEUROLOGY

High inter-reviewer variability of spike detection on intracranial EEG addressed by an automated multi-channel algorithm

(2011) Daniel T. Barkmeier et al.   CLINICAL NEUROPHYSIOLOGY

Amyloid- /Fyn-Induced Synaptic, Network, and Cognitive Impairments Depend on Tau Levels in Multiple Mouse Models of Alzheimer's Disease

(2011) E. D. Roberson et al.   JOURNAL OF NEUROSCIENCE

Glutamate release by primary brain tumors induces epileptic activity

(2011) Susan C Buckingham et al.   NATURE MEDICINE

The role of spreading depression, spreading depolarization and spreading ischemia in neurological disease

(2011) Jens P Dreier   NATURE MEDICINE

Apolipoprotein E4 Causes Age- and Tau-Dependent Impairment of GABAergic Interneurons, Leading to Learning and Memory Deficits in Mice

(2010) Y. Andrews-Zwilling et al.   JOURNAL OF NEUROSCIENCE

GABAergic Interneuron Dysfunction Impairs Hippocampal Neurogenesis in Adult Apolipoprotein E4 Knockin Mice

(2009) Gang Li et al.   Cell Stem Cell

Increased number of microglia in the brain of severe combined immunodeficient (SCID) mice

(2008) Dietrich E. Lorke et al.   HISTOCHEMISTRY AND CELL BIOLOGY