Glioma-mediated microglial activation promotes glioma proliferation and migration: roles of Na+/H+exchanger isoform 1

CIAPIN1 targets Na+/H+ exchanger 1 to mediate MDA-MB-231 cells׳ metastasis through regulation of MMPs via ERK1/2 signaling pathway

(2015) Jian Wang et al.   EXPERIMENTAL CELL RESEARCH

Glioblastoma-derived Macrophage Colony-stimulating Factor (MCSF) Induces Microglial Release of Insulin-like Growth Factor-binding Protein 1 (IGFBP1) to Promote Angiogenesis

(2015) Mamatha Bangalore Nijaguna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Involvement of purinergic system in the release of cytokines by macrophages exposed to glioma-conditioned medium

(2015) Letícia Scussel Bergamin et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Inhibition of endogenous heat shock protein 70 attenuates inducible nitric oxide synthase induction via disruption of heat shock protein 70/Na+/H+ exchanger 1-Ca2+-calcium-calmodulin-dependent protein kinase II/transforming growth factor β-activated kinas

(2015) Chao Huang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Glioma-Associated Microglia/Macrophages Display an Expression Profile Different from M1 and M2 Polarization and Highly Express Gpnmb and Spp1

(2015) Frank Szulzewsky et al.   PLoS One

Activation of Multiple ERBB Family Receptors Mediates Glioblastoma Cancer Stem-like Cell Resistance to EGFR-Targeted Inhibition

(2015) Paul A. Clark et al.   NEOPLASIA

CNS macrophages and peripheral myeloid cells in brain tumours

(2014) Rainer Glass et al.   ACTA NEUROPATHOLOGICA

Upregulation of NHE1 protein expression enables glioblastoma cells to escape TMZ-mediated toxicity via increased H+extrusion, cell migration and survival

(2014) Damin Cong et al.   CARCINOGENESIS

Glioma-associated microglial MMP9 expression is upregulated by TLR2 signaling and sensitive to minocycline

(2014) Feng Hu et al.   INTERNATIONAL JOURNAL OF CANCER

Astrocytic Regulation of Human Monocytic/Microglial Activation

(2014) A. M. Kostianovsky et al.   JOURNAL OF IMMUNOLOGY

WNK1-OSR1 kinase-mediated phospho-activation of Na+-K+-2Cl- cotransporter facilitates glioma migration

(2014) Wen Zhu et al.   Molecular Cancer

A neurocentric perspective on glioma invasion

(2014) Vishnu Anand Cuddapah et al.   NATURE REVIEWS NEUROSCIENCE

CSF-1 Receptor Signaling in Myeloid Cells

(2014) E. R. Stanley et al.   Cold Spring Harbor Perspectives in Biology

Molecular Mechanisms That Influence the Macrophage M1–M2 Polarization Balance

(2014) Nan Wang et al.   Frontiers in Immunology

Regulation of the Na+/H+ Exchanger (NHE1) in Breast Cancer Metastasis

(2013) S. R. Amith et al.   CANCER RESEARCH

Monocyte chemoattractant protein-1 and the blood–brain barrier

(2013) Yao Yao et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Controversial Role of Microglia in Malignant Gliomas

(2013) Jun Wei et al.   Clinical & Developmental Immunology

Review: Molecular mechanism of microglia stimulated glioblastoma invasion

(2013) Salvatore J. Coniglio et al.   MATRIX BIOLOGY

Toll-like receptor 2 mediates microglia/brain macrophage MT1-MMP expression and glioma expansion

(2013) K. Vinnakota et al.   NEURO-ONCOLOGY

Stimulation of Na+/H+ Exchanger Isoform 1 Promotes Microglial Migration

(2013) Yejie Shi et al.   PLoS One

microRNA-100 Targets SMRT/NCOR2, Reduces Proliferation, and Improves Survival in Glioblastoma Animal Models

(2013) Bahauddeen M. Alrfaei et al.   PLoS One

Differential Expression of 2',3'-Cyclic-Nucleotide 3'-Phosphodiesterase and Neural Lineage Markers Correlate with Glioblastoma Xenograft Infiltration and Patient Survival

(2012) M. Zorniak et al.   CLINICAL CANCER RESEARCH

Physiology, Pharmacology and Pathophysiology of the pH Regulatory Transport Proteins NHE1 and NBCn1: Similarities, Differences, and Implications for Cancer Therapy

(2012) E. Boedtkjer et al.   CURRENT PHARMACEUTICAL DESIGN

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

The molecular profile of microglia under the influence of glioma

(2012) W. Li et al.   NEURO-ONCOLOGY

Tumor Metastasis: Molecular Insights and Evolving Paradigms

(2011) Scott Valastyan et al.   CELL

NHE1 mediates MDA-MB-231 cells invasion through the regulation of MT1-MMP

(2011) Yani Lin et al.   EXPERIMENTAL CELL RESEARCH

The brain tumor microenvironment

(2011) Nikki A. Charles et al.   GLIA

Role of sodium/hydrogen exchanger isoform 1 in microglial activation and proinflammatory responses in ischemic brains

(2011) Yejie Shi et al.   JOURNAL OF NEUROCHEMISTRY

MK-2206, a Novel Allosteric Inhibitor of Akt, Synergizes with Gefitinib against Malignant Glioma via Modulating Both Autophagy and Apoptosis

(2011) Y. Cheng et al.   MOLECULAR CANCER THERAPEUTICS

Temozolomide: Mechanisms of Action, Repair and Resistance

(2011) Jihong Zhang et al.   Current Molecular Pharmacology

Activation of Microglia Depends on Na+/H+ Exchange-Mediated H+ Homeostasis

(2010) Y. Liu et al.   JOURNAL OF NEUROSCIENCE

Glioma cancer stem cells induce immunosuppressive macrophages/microglia

(2010) Adam Wu et al.   NEURO-ONCOLOGY

Mislocalized Scaffolding by the Na-H Exchanger NHE1 Dominantly Inhibits Fibronectin Production and TGF-β Activation

(2009) Anastasios Karydis et al.   MOLECULAR BIOLOGY OF THE CELL

Advances in the genetics of glioblastoma: are we reaching critical mass?

(2009) Benjamin Purow et al.   Nature Reviews Neurology

Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion

(2009) D. S. Markovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting Interleukin 6 Signaling Suppresses Glioma Stem Cell Survival and Tumor Growth

(2009) Hui Wang et al.   STEM CELLS

NF- B as a Critical Link Between Inflammation and Cancer

(2009) M. Karin   Cold Spring Harbor Perspectives in Biology

p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation

(2008) Hongwu Zheng et al.   NATURE

Macrophage activation and polarization

(2007) Fernando Oneissi Martinez   Frontiers in Bioscience-Landmark