PIK3CA variants selectively initiate brain hyperactivity during gliomagenesis

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Systematic Functional Annotation of Somatic Mutations in Cancer

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Cooperative p16 and p21 action protects female astrocytes from transformation

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Identification of diverse astrocyte populations and their malignant analogs

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Cell Biology of Astrocyte-Synapse Interactions

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Colocalization of synapse marker proteins evaluated by STED-microscopy reveals patterns of neuronal synapse distribution in vitro

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Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

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Functional annotation of rare gene aberration drivers of pancreatic cancer

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Identification of Variant-Specific Functions of PIK3CA by Rapid Phenotyping of Rare Mutations

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Neuronal Activity Promotes Glioma Growth through Neuroligin-3 Secretion

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Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity

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Excitatory/Inhibitory Balance and Circuit Homeostasis in Autism Spectrum Disorders

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Mouse models of human PIK3CA-related brain overgrowth have acutely treatable epilepsy

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Pan-Cancer Analysis of Mutation Hotspots in Protein Domains

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PIK3CA-related overgrowth spectrum (PROS): Diagnostic and testing eligibility criteria, differential diagnosis, and evaluation

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Discovery of co-occurring driver pathways in cancer

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GABAergic disinhibition and impaired KCC2 cotransporter activity underlie tumor-associated epilepsy

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Discovery and saturation analysis of cancer genes across 21 tumour types

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A global assessment of cancer genomic alterations in epigenetic mechanisms

(2014) Muhammad A Shah et al.   Epigenetics & Chromatin

The Somatic Genomic Landscape of Glioblastoma

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Unbiased Discovery of Glypican as a Receptor for LRRTM4 in Regulating Excitatory Synapse Development

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Cancer Genome Landscapes

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A method for stable transgenesis of radial glia lineage in rat neocortex by piggyBac mediated transposition

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Astrocyte glypicans 4 and 6 promote formation of excitatory synapses via GluA1 AMPA receptors

(2012) Nicola J. Allen et al.   NATURE

Glutamate release by primary brain tumors induces epileptic activity

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Advances in understanding cancer genomes through second-generation sequencing

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Failure of neuronal homeostasis results in common neuropsychiatric phenotypes

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Comprehensive genomic characterization defines human glioblastoma genes and core pathways

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