标题
Interleukin‐22 and intestinal homeostasis: Protective or destructive?
作者
关键词
-
出版物
IUBMB LIFE
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2020-05-05
DOI
10.1002/iub.2295
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- The development of colitis in Il10−/− mice is dependent on IL-22
- (2020) Dilini C. Gunasekera et al. Mucosal Immunology
- Macrophage β2-Integrins Regulate IL-22 by ILC3s and Protect from Lethal Citrobacter rodentium-Induced Colitis
- (2019) Baomei Wang et al. Cell Reports
- Interleukin-22 protects intestinal stem cells against genotoxic stress
- (2019) Konrad Gronke et al. NATURE
- IL-22–Independent Protection from Colitis in the Absence of Nkx2.3 Transcription Factor in Mice
- (2019) Zoltán Kellermayer et al. JOURNAL OF IMMUNOLOGY
- IL-10 Family Cytokines IL-10 and IL-22: from Basic Science to Clinical Translation
- (2019) Wenjun Ouyang et al. IMMUNITY
- Role of Th22 cells in Helicobacter pylori-related gastritis and peptic ulcer diseases
- (2019) Ahmad Sanaii et al. MOLECULAR BIOLOGY REPORTS
- IFN-I and IL-22 mediate protective effects of intestinal viral infection
- (2019) Jessica A Neil et al. Nature Microbiology
- IL-23–producing IL-10Rα–deficient gut macrophages elicit an IL-22–driven proinflammatory epithelial cell response
- (2019) Biana Bernshtein et al. Science Immunology
- Loss of adenomatous polyposis coli function renders intestinal epithelial cells resistant to the cytokine IL-22
- (2019) Yu Chen et al. PLOS BIOLOGY
- Molecular signature of interleukin-22 in colon carcinoma cells and organoid models
- (2019) Ina Rudloff et al. Translational Research
- The expression analysis of Fra-1 gene and IL-11 protein in Iranian patients with ulcerative colitis
- (2018) Milad Sabzevary-Ghahfarokhi et al. BMC IMMUNOLOGY
- Intensified Th9 Response is Associated with the Immunopathogenesis of Active Ulcerative Colitis
- (2018) Mojtaba Shohan et al. IMMUNOLOGICAL INVESTIGATIONS
- Anti-TNF Therapy Induces CD4+ T-Cell Production of IL-22 and Promotes Epithelial Repairs in Patients With Crohn’s Disease
- (2018) Leilei Fang et al. INFLAMMATORY BOWEL DISEASES
- Th9 Cells: Probable players in ulcerative colitis pathogenesis
- (2018) Mojtaba Shohan et al. INTERNATIONAL REVIEWS OF IMMUNOLOGY
- Mesenchymal Stromal Cells Stimulate the Proliferation and IL-22 Production of Group 3 Innate Lymphoid Cells
- (2018) Vera van Hoeven et al. JOURNAL OF IMMUNOLOGY
- Elevated Expression of Serum Amyloid A 3 Protects Colon Epithelium Against Acute Injury Through TLR2-Dependent Induction of Neutrophil IL-22 Expression in a Mouse Model of Colitis
- (2018) Gufang Zhang et al. Frontiers in Immunology
- ATF3 Sustains IL-22-Induced STAT3 Phosphorylation to Maintain Mucosal Immunity Through Inhibiting Phosphatases
- (2018) Doaa Glal et al. Frontiers in Immunology
- Biological and pathological activities of interleukin-22
- (2016) Mirna Perusina Lanfranca et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Interleukin-22 regulates antimicrobial peptide expression and keratinocyte differentiation to control Staphylococcus aureus colonization of the nasal mucosa
- (2016) M E Mulcahy et al. Mucosal Immunology
- Interleukin-22: Immunobiology and Pathology
- (2015) Jarrod A. Dudakov et al. Annual Review of Immunology
- The Human IL-22 Receptor Is Regulated through the Action of the Novel E3 Ligase Subunit FBXW12, Which Functions as an Epithelial Growth Suppressor
- (2015) Joseph Franz et al. Journal of Immunology Research
- Role of interleukin-22 in inflammatory bowel disease
- (2015) Lin-Jing Li WORLD JOURNAL OF GASTROENTEROLOGY
- Interleukin-22: A likely target for treatment of autoimmune diseases
- (2014) Xuyan Yang et al. AUTOIMMUNITY REVIEWS
- The Chemokine Receptor CXCR6 Controls the Functional Topography of Interleukin-22 Producing Intestinal Innate Lymphoid Cells
- (2014) Naoko Satoh-Takayama et al. IMMUNITY
- IL-22+CD4+ T Cells Promote Colorectal Cancer Stemness via STAT3 Transcription Factor Activation and Induction of the Methyltransferase DOT1L
- (2014) Ilona Kryczek et al. IMMUNITY
- Induction of Innate Lymphoid Cell-Derived Interleukin-22 by the Transcription Factor STAT3 Mediates Protection against Intestinal Infection
- (2014) Xiaohuan Guo et al. IMMUNITY
- Glycogen Synthase Kinase-3β Stabilizes the Interleukin (IL)-22 Receptor from Proteasomal Degradation in Murine Lung Epithelia
- (2014) Nathaniel M. Weathington et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- EMerging BiomARKers in Inflammatory Bowel Disease (EMBARK) Study Identifies Fecal Calprotectin, Serum MMP9 and Serum IL-22 as a Novel Combination of Biomarkers for Crohn's Disease Activity: Role of Cross-Sectional Imaging
- (2013) William A Faubion et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Reciprocal Expression of Enteric Antimicrobial Proteins in Intestinal Graft-Versus-Host Disease
- (2013) Yoshihiro Eriguchi et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- IL-22 is related to development of human colon cancer by activation of STAT3
- (2013) Runqiu Jiang et al. BMC CANCER
- Expansion of the Homeostasis Model Assessment of -Cell Function and Insulin Resistance to Enable Clinical Trial Outcome Modeling Through the Interactive Adjustment of Physiology and Treatment Effects: iHOMA2
- (2013) N. R. Hill et al. DIABETES CARE
- Interleukin-22, liver progenitor cells, and liver cancer
- (2013) Dechun Feng HEPATOLOGY
- Group 3 Innate Lymphoid Cells Inhibit T-Cell-Mediated Intestinal Inflammation through Aryl Hydrocarbon Receptor Signaling and Regulation of Microflora
- (2013) Ju Qiu et al. IMMUNITY
- IL-22, not simply a Th17 cytokine
- (2013) Sascha Rutz et al. IMMUNOLOGICAL REVIEWS
- Acute infection of mice withClostridium difficileleads to eIF2α phosphorylation and pro-survival signalling as part of the mucosal inflammatory response
- (2013) Amir A. Sadighi Akha et al. IMMUNOLOGY
- Deletion of Intestinal Epithelial Cell STAT3 Promotes T-Lymphocyte STAT3 Activation and Chronic Colitis Following Acute Dextran Sodium Sulfate Injury in Mice
- (2013) Tara A. Willson et al. INFLAMMATORY BOWEL DISEASES
- Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model
- (2013) Stefanie Kirchberger et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Retinoic acid expression associates with enhanced IL-22 production by γδ T cells and innate lymphoid cells and attenuation of intestinal inflammation
- (2013) Lisa A. Mielke et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IL-22-producing CD4+ cells are depleted in actively inflamed colitis tissue
- (2013) J M Leung et al. Mucosal Immunology
- Therapeutic opportunities of the IL-22–IL-22R1 system
- (2013) Robert Sabat et al. NATURE REVIEWS DRUG DISCOVERY
- Immunomodulation by Bifidobacterium infantis 35624 in the Murine Lamina Propria Requires Retinoic Acid-Dependent and Independent Mechanisms
- (2013) Patrycja Konieczna et al. PLoS One
- IL-22-producing neutrophils contribute to antimicrobial defense and restitution of colonic epithelial integrity during colitis
- (2013) C. L. Zindl et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dysbiosis—A consequence of Paneth cell dysfunction
- (2013) Nita H. Salzman et al. SEMINARS IN IMMUNOLOGY
- IL-22: An Evolutionary Missing-Link Authenticating the Role of the Immune System in Tissue Regeneration
- (2013) Pawan Kumar et al. Journal of Cancer
- CD8+Sézary syndrome with interleukin-22 production modulated by bacterial sepsis
- (2012) T. Shimauchi et al. BRITISH JOURNAL OF DERMATOLOGY
- Aryl Hydrocarbon Receptor Regulates Pancreatic IL-22 Production and Protects Mice From Acute Pancreatitis
- (2012) Jing Xue et al. GASTROENTEROLOGY
- Interleukin-22 Promotes Proliferation of Liver Stem/Progenitor Cells in Mice and Patients With Chronic Hepatitis B Virus Infection
- (2012) Dechun Feng et al. GASTROENTEROLOGY
- Interleukin-22 Protects Intestinal Stem Cells from Immune-Mediated Tissue Damage and Regulates Sensitivity to Graft versus Host Disease
- (2012) Alan M. Hanash et al. IMMUNITY
- Increased levels of circulating Th17 cells in quiescent versus active Crohn's disease
- (2012) Anders Dige et al. Journal of Crohns & Colitis
- Cutting Edge: A Variant of the IL-23R Gene Associated with Inflammatory Bowel Disease Induces Loss of MicroRNA Regulation and Enhanced Protein Production
- (2012) A. Zwiers et al. JOURNAL OF IMMUNOLOGY
- IL-22 Mediates Host Defense against an Intestinal Intracellular Parasite in the Absence of IFN- at the Cost of Th17-Driven Immunopathology
- (2012) J. Stange et al. JOURNAL OF IMMUNOLOGY
- IL-22 Promotes Fibroblast-Mediated Wound Repair in the Skin
- (2012) Heather M. McGee et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- IL-22 from conventional NK cells is epithelial regenerative and inflammation protective during influenza infection
- (2012) P Kumar et al. Mucosal Immunology
- A role for mucosal IL-22 production and Th22 cells in HIV-associated mucosal immunopathogenesis
- (2012) C J Kim et al. Mucosal Immunology
- IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine
- (2012) Samuel Huber et al. NATURE
- Mucin Muc2 Deficiency and Weaning Influences the Expression of the Innate Defense Genes Reg3β, Reg3γ and Angiogenin-4
- (2012) Nanda Burger-van Paassen et al. PLoS One
- Innate Lymphoid Cells Promote Anatomical Containment of Lymphoid-Resident Commensal Bacteria
- (2012) G. F. Sonnenberg et al. SCIENCE
- Interleukin-22 Drives Endogenous Thymic Regeneration in Mice
- (2012) J. A. Dudakov et al. SCIENCE
- Potential involvement of IL-22 and IL-22-producing cells in the inflamed salivary glands of patients with Sjögren's syndrome
- (2011) Francesco Ciccia et al. ANNALS OF THE RHEUMATIC DISEASES
- Aryl Hydrocarbon Receptor-Induced Signals Up-regulate IL-22 Production and Inhibit Inflammation in the Gastrointestinal Tract
- (2011) Ivan Monteleone et al. GASTROENTEROLOGY
- In vivo consequences of liver-specific interleukin-22 expression in mice: Implications for human liver disease progression
- (2011) Ogyi Park et al. HEPATOLOGY
- The Aryl Hydrocarbon Receptor Regulates Gut Immunity through Modulation of Innate Lymphoid Cells
- (2011) Ju Qiu et al. IMMUNITY
- Caspase-1-Processed Cytokines IL-1 and IL-18 Promote IL-17 Production by and CD4 T Cells That Mediate Autoimmunity
- (2011) S. J. Lalor et al. JOURNAL OF IMMUNOLOGY
- Genetics and pathogenesis of inflammatory bowel disease
- (2011) Bernard Khor et al. NATURE
- Transcription factor c-Maf mediates the TGF-β-dependent suppression of IL-22 production in TH17 cells
- (2011) Sascha Rutz et al. NATURE IMMUNOLOGY
- RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota
- (2011) Shinichiro Sawa et al. NATURE IMMUNOLOGY
- AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch
- (2011) Jacob S Lee et al. NATURE IMMUNOLOGY
- Interleukin-22 genetic polymorphisms and risk of colon cancer
- (2010) Cheryl L. Thompson et al. CANCER CAUSES & CONTROL
- Interleukin-22: A cytokine produced by T, NK and NKT cell subsets, with importance in the innate immune defense and tissue protection
- (2010) Ellen Witte et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Regulated Expression of Nuclear Receptor RORγt Confers Distinct Functional Fates to NK Cell Receptor-Expressing RORγt+ Innate Lymphocytes
- (2010) Cedric Vonarbourg et al. IMMUNITY
- DMBT1 is a novel gene induced by IL-22 in ulcerative colitis
- (2010) Hirokazu Fukui et al. INFLAMMATORY BOWEL DISEASES
- IL-17 Amplifies Human Contact Hypersensitivity by Licensing Hapten Nonspecific Th1 Cells to Kill Autologous Keratinocytes
- (2010) D. Pennino et al. JOURNAL OF IMMUNOLOGY
- IL-17A-Producing T and Th17 Lymphocytes Mediate Lung Inflammation but Not Fibrosis in Experimental Silicosis
- (2010) S. Lo Re et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: Crucial Role of IL-1 and IL-23 in the Innate IL-17 Response of Peripheral Lymph Node NK1.1- Invariant NKT Cells to Bacteria
- (2010) J.-M. Doisne et al. JOURNAL OF IMMUNOLOGY
- IL-22 Induces an Acute-Phase Response
- (2010) S. C. Liang et al. JOURNAL OF IMMUNOLOGY
- Redundant and Pathogenic Roles for IL-22 in Mycobacterial, Protozoan, and Helminth Infections
- (2010) M. S. Wilson et al. JOURNAL OF IMMUNOLOGY
- Cytokine Requirements for the Differentiation and Expansion of IL-17A- and IL-22-Producing Human V 2V 2 T Cells
- (2010) K. J. Ness-Schwickerath et al. JOURNAL OF IMMUNOLOGY
- Analysis of CD161 expression on human CD8+ T cells defines a distinct functional subset with tissue-homing properties
- (2010) E. Billerbeck et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Interleukin-1 and IL-23 Induce Innate IL-17 Production from γδ T Cells, Amplifying Th17 Responses and Autoimmunity
- (2009) Caroline E. Sutton et al. IMMUNITY
- STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing
- (2009) Geethanjali Pickert et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Ulcerative colitis–risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study
- (2009) Mark S Silverberg et al. NATURE GENETICS
- Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells
- (2009) Thomas Duhen et al. NATURE IMMUNOLOGY
- Crystallization and preliminary X-ray diffraction analysis of human IL-22 bound to the extracellular IL-22R1 chain
- (2008) Brandi C. Jones et al. Acta Crystallographica Section F-Structural Biology and Crystallization Communications
- Crystal structure of the IL-22/IL-22R1 complex and its implications for the IL-22 signaling mechanism
- (2008) Lucas Bleicher et al. FEBS LETTERS
- RORγ-Expressing Th17 Cells Induce Murine Chronic Intestinal Inflammation via Redundant Effects of IL-17A and IL-17F
- (2008) Moritz Leppkes et al. GASTROENTEROLOGY
- Innate and Adaptive Interleukin-22 Protects Mice from Inflammatory Bowel Disease
- (2008) Lauren A. Zenewicz et al. IMMUNITY
- Thymic Selection Determines γδ T Cell Effector Fate: Antigen-Naive Cells Make Interleukin-17 and Antigen-Experienced Cells Make Interferon γ
- (2008) Kirk D.C. Jensen et al. IMMUNITY
- Microbial Flora Drives Interleukin 22 Production in Intestinal NKp46+ Cells that Provide Innate Mucosal Immune Defense
- (2008) Naoko Satoh-Takayama et al. IMMUNITY
- Differential regulation of interleukin 12 and interleukin 23 production in human dendritic cells
- (2008) Franca Gerosa et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Patients with Chronic Mucocutaneous Candidiasis Exhibit Reduced Production of Th17-Associated Cytokines IL-17 and IL-22
- (2008) Kilian Eyerich et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity
- (2008) Marina Cella et al. NATURE
- RORγt and commensal microflora are required for the differentiation of mucosal interleukin 22–producing NKp46+ cells
- (2008) Stephanie L Sanos et al. NATURE IMMUNOLOGY
- Human fetal lymphoid tissue–inducer cells are interleukin 17–producing precursors to RORC+ CD127+ natural killer–like cells
- (2008) Tom Cupedo et al. NATURE IMMUNOLOGY
- IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia
- (2008) Shean J Aujla et al. NATURE MEDICINE
- Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens
- (2008) Yan Zheng et al. NATURE MEDICINE
- Interleukin-22 Forms Dimers that are Recognized by Two Interleukin-22R1 Receptor Chains
- (2007) Mario de Oliveira Neto et al. BIOPHYSICAL JOURNAL
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