eEF2K/eEF2 Pathway Controls the Excitation/Inhibition Balance and Susceptibility to Epileptic Seizures

Dorsal hippocampus infusions of CNQX into the dentate gyrus disrupt expression of trace fear conditioning

(2015) Jamie L. Pierson et al.   HIPPOCAMPUS

Eukaryotic elongation factor 2 kinase regulates the synthesis of microtubule-related proteins in neurons

(2015) Justin W. Kenney et al.   JOURNAL OF NEUROCHEMISTRY

Bidirectional Regulation of eEF2 Phosphorylation Controls Synaptic Plasticity by Decoding Neuronal Activity Patterns

(2015) P. K. McCamphill et al.   JOURNAL OF NEUROSCIENCE

PKR Inhibition Rescues Memory Deficit and ATF4 Overexpression in ApoE  4 Human Replacement Mice

(2015) Y. Segev et al.   JOURNAL OF NEUROSCIENCE

Dynamics of Elongation Factor 2 Kinase Regulation in Cortical Neurons in Response to Synaptic Activity

(2015) J. W. Kenney et al.   JOURNAL OF NEUROSCIENCE

Elongation Factor 2 Kinase Is Regulated by Proline Hydroxylation and Protects Cells during Hypoxia

(2015) Claire E. J. Moore et al.   MOLECULAR AND CELLULAR BIOLOGY

From the genetic architecture to synaptic plasticity in autism spectrum disorder

(2015) Thomas Bourgeron   NATURE REVIEWS NEUROSCIENCE

Translational Control in Synaptic Plasticity and Cognitive Dysfunction

(2014) Shelly A. Buffington et al.   Annual Review of Neuroscience

Inhibition of AMP-Activated Protein Kinase Signaling Alleviates Impairments in Hippocampal Synaptic Plasticity Induced by Amyloid  

(2014) T. Ma et al.   JOURNAL OF NEUROSCIENCE

Genetic or Pharmacological Reduction of PERK Enhances Cortical-Dependent Taste Learning

(2014) H. Ounallah-Saad et al.   JOURNAL OF NEUROSCIENCE

Translational control of mGluR-dependent long-term depression and object-place learning by eIF2α

(2014) Gonzalo Viana Di Prisco et al.   NATURE NEUROSCIENCE

Dendritic Spines: The Locus of Structural and Functional Plasticity

(2014) Carlo Sala et al.   PHYSIOLOGICAL REVIEWS

Elongation factor-2 phosphorylation in dendrites and the regulation of dendritic mRNA translation in neurons

(2014) Christopher Heise et al.   Frontiers in Cellular Neuroscience

Pharmacogenetic Inhibition of eIF4E-Dependent Mmp9 mRNA Translation Reverses Fragile X Syndrome-like Phenotypes

(2014) Christos G. Gkogkas et al.   Cell Reports

The roles of protein expression in synaptic plasticity and memory consolidation

(2014) Tali Rosenberg et al.   Frontiers in Molecular Neuroscience

Acute Suppression of Spontaneous Neurotransmission Drives Synaptic Potentiation

(2013) E. Nosyreva et al.   JOURNAL OF NEUROSCIENCE

The role of eEF2 pathway in learning and synaptic plasticity

(2013) Elham Taha et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

The Central Dogma Decentralized: New Perspectives on RNA Function and Local Translation in Neurons

(2013) Christine E. Holt et al.   NEURON

Dentate gyrus network dysfunctions precede the symptomatic phase in a genetic mouse model of seizures

(2013) Oana Toader et al.   Frontiers in Cellular Neuroscience

Synapsin II desynchronizes neurotransmitter release at inhibitory synapses by interacting with presynaptic calcium channels

(2013) Lucian Medrihan et al.   Nature Communications

Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase

(2012) Sébastien Pyr Dit Ruys et al.   BIOCHEMICAL JOURNAL

Synaptic and Extrasynaptic Origin of the Excitation/Inhibition Imbalance in the Hippocampus of Synapsin I/II/III Knockout Mice

(2012) P. Farisello et al.   CEREBRAL CORTEX

Temporal evolution of neurophysiological and behavioral features of synapsin I/II/III triple knock-out mice

(2012) Marco Cambiaghi et al.   EPILEPSY RESEARCH

Impaired associative taste learning and abnormal brain activation in kinase-defective eEF2K mice

(2012) I. Gildish et al.   LEARNING & MEMORY

Autism-related deficits via dysregulated eIF4E-dependent translational control

(2012) Christos G. Gkogkas et al.   NATURE

Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2

(2012) Michael J. Schmeisser et al.   NATURE

Exaggerated translation causes synaptic and behavioural aberrations associated with autism

(2012) Emanuela Santini et al.   NATURE

ApoE ε4 is associated with eIF2α phosphorylation and impaired learning in young mice

(2012) Yifat Segev et al.   NEUROBIOLOGY OF AGING

Hilar Mossy Cell Degeneration Causes Transient Dentate Granule Cell Hyperexcitability and Impaired Pattern Separation

(2012) Seiichiro Jinde et al.   NEURON

Genetic Removal of p70 S6 Kinase 1 Corrects Molecular, Synaptic, and Behavioral Phenotypes in Fragile X Syndrome Mice

(2012) Aditi Bhattacharya et al.   NEURON

Tonic GABAA receptor-mediated signalling in temporal lobe epilepsy

(2012) Ivan Pavlov et al.   NEUROPHARMACOLOGY

Pharmacologic Rescue of Impaired Cognitive Flexibility, Social Deficits, Increased Aggression, and Seizure Susceptibility in Oxytocin Receptor Null Mice: A Neurobehavioral Model of Autism

(2011) Mariaelvina Sala et al.   BIOLOGICAL PSYCHIATRY

Suppression of PKR Promotes Network Excitability and Enhanced Cognition by Interferon-γ-Mediated Disinhibition

(2011) Ping Jun Zhu et al.   CELL

Concerted action of zinc and ProSAP/Shank in synaptogenesis and synapse maturation

(2011) Andreas M Grabrucker et al.   EMBO JOURNAL

SYN1 loss-of-function mutations in autism and partial epilepsy cause impaired synaptic function

(2011) Anna Fassio et al.   HUMAN MOLECULAR GENETICS

NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses

(2011) Anita E. Autry et al.   NATURE

Inhibition of the interactions between eukaryotic initiation factors 4E and 4G impairs long-term associative memory consolidation but not reconsolidation

(2011) C. A. Hoeffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Translational Control Mechanisms in Long-lasting Synaptic Plasticity and Memory

(2010) Christos Gkogkas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synaptic Activity Controls Dendritic Spine Morphology by Modulating eEF2-Dependent BDNF Synthesis

(2010) C. Verpelli et al.   JOURNAL OF NEUROSCIENCE

Comparison between spontaneous and kainate-induced gamma oscillations in the mouse hippocampusin vitro

(2009) Alexander N.J. Pietersen et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Expression of mutant β2 nicotinic receptors during development is crucial for epileptogenesis

(2009) Irene Manfredi et al.   HUMAN MOLECULAR GENETICS

Biphasic Activation of the mTOR Pathway in the Gustatory Cortex Is Correlated with and Necessary for Taste Learning

(2009) K. Belelovsky et al.   JOURNAL OF NEUROSCIENCE

SUnSET, a nonradioactive method to monitor protein synthesis

(2009) Enrico K Schmidt et al.   NATURE METHODS

Post-Training Dephosphorylation of eEF-2 Promotes Protein Synthesis for Memory Consolidation

(2009) Heh-In Im et al.   PLoS One

Pilocarpine-Induced Seizures Revisited: What Does the Model Mimic?

(2009)   Epilepsy Currents

Dissociating space and trace in dorsal and ventral hippocampus

(2008) Jennifer Czerniawski et al.   HIPPOCAMPUS

NS21: Re-defined and modified supplement B27 for neuronal cultures

(2008) Yucui Chen et al.   JOURNAL OF NEUROSCIENCE METHODS

ERK-dependent PSD-95 induction in the gustatory cortex is necessary for taste learning, but not retrieval

(2008) Alina Elkobi et al.   NATURE NEUROSCIENCE

Activity-Dependent Regulation of Synaptic AMPA Receptor Composition and Abundance by β3 Integrins

(2008) Lorenzo A. Cingolani et al.   NEURON

Elongation Factor 2 and Fragile X Mental Retardation Protein Control the Dynamic Translation of Arc/Arg3.1 Essential for mGluR-LTD

(2008) Sungjin Park et al.   NEURON

Increased severity of pentylenetetrazol induced seizures in leptin deficient ob/ob mice

(2008) Ebru Erbayat-Altay et al.   NEUROSCIENCE LETTERS

Epilepsy in Dcx Knockout Mice Associated with Discrete Lamination Defects and Enhanced Excitability in the Hippocampus

(2008) Marika Nosten-Bertrand et al.   PLoS One