Exaggerated translation causes synaptic and behavioural aberrations associated with autism

Disrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome

(2012) Jennifer A Ronesi et al.   NATURE NEUROSCIENCE

Mutations causing syndromic autism define an axis of synaptic pathophysiology

(2011) Benjamin D. Auerbach et al.   NATURE

Neocortical excitation/inhibition balance in information processing and social dysfunction

(2011) Ofer Yizhar et al.   NATURE

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

(2011) João Peça et al.   NATURE

High-throughput, detailed, cell-specific neuroanatomy of dendritic spines using microinjection and confocal microscopy

(2011) Dani Dumitriu et al.   Nature Protocols

Impaired social interactions and motor learning skills in tuberous sclerosis complex model mice expressing a dominant/negative form of tuberin

(2011) Itzamarie Chévere-Torres et al.   NEUROBIOLOGY OF DISEASE

Inhibition of the interactions between eukaryotic initiation factors 4E and 4G impairs long-term associative memory consolidation but not reconsolidation

(2011) C. A. Hoeffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysregulation of mTOR Signaling in Fragile X Syndrome

(2010) A. Sharma et al.   JOURNAL OF NEUROSCIENCE

Neuroligin-1 Deletion Results in Impaired Spatial Memory and Increased Repetitive Behavior

(2010) J. Blundell et al.   JOURNAL OF NEUROSCIENCE

GABAB Receptors Modulate NMDA Receptor Calcium Signals in Dendritic Spines

(2010) Jason R. Chalifoux et al.   NEURON

The genetic and neurobiologic compass points toward common signaling dysfunctions in autism spectrum disorders

(2009) Pat Levitt et al.   JOURNAL OF CLINICAL INVESTIGATION

Deregulation of EIF4E: a novel mechanism for autism

(2009) M Neves-Pereira et al.   JOURNAL OF MEDICAL GENETICS

Pharmacological Inhibition of mTORC1 Suppresses Anatomical, Cellular, and Behavioral Abnormalities in Neural-Specific Pten Knock-Out Mice

(2009) J. Zhou et al.   JOURNAL OF NEUROSCIENCE

SUnSET, a nonradioactive method to monitor protein synthesis

(2009) Enrico K Schmidt et al.   NATURE METHODS

Probing Compulsive and Impulsive Behaviors, from Animal Models to Endophenotypes: A Narrative Review

(2009) Naomi A Fineberg et al.   NEUROPSYCHOPHARMACOLOGY

Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety

(2009) Alexia Thomas et al.   PSYCHOPHARMACOLOGY

The Autistic Neuron: Troubled Translation?

(2008) Raymond J. Kelleher et al.   CELL

Reversal of learning deficits in a Tsc2 +/− mouse model of tuberous sclerosis

(2008) Dan Ehninger et al.   NATURE MEDICINE

Removal of FKBP12 Enhances mTOR-Raptor Interactions, LTP, Memory, and Perseverative/Repetitive Behavior

(2008) Charles A. Hoeffer et al.   NEURON

Autism: Definition, Neurobiology, Screening, Diagnosis

(2008) Isabelle Rapin et al.   PEDIATRIC CLINICS OF NORTH AMERICA

The GTP-binding protein Rhes modulates dopamine signalling in striatal medium spiny neurons

(2007) Francesco Errico et al.   MOLECULAR AND CELLULAR NEUROSCIENCE