Pathophysiology Associated with Traumatic Brain Injury: Current Treatments and Potential Novel Therapeutics
出版年份 2016 全文链接
标题
Pathophysiology Associated with Traumatic Brain Injury: Current Treatments and Potential Novel Therapeutics
作者
关键词
Traumatic brain injury, Blood–brain barrier, Neuroinflammation, Biologics, Caveolin, Membrane/lipid rafts
出版物
CELLULAR AND MOLECULAR NEUROBIOLOGY
Volume 37, Issue 4, Pages 571-585
出版商
Springer Nature
发表日期
2016-07-07
DOI
10.1007/s10571-016-0400-1
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Combination therapies for neurobehavioral and cognitive recovery after experimental traumatic brain injury: Is more better?
- (2016) Anthony E. Kline et al. PROGRESS IN NEUROBIOLOGY
- Neuroprotective effects of nitidine against traumatic CNS injury via inhibiting microglia activation
- (2015) Yimin Yuan et al. BRAIN BEHAVIOR AND IMMUNITY
- Macrophage activation and its role in repair and pathology after spinal cord injury
- (2015) John C. Gensel et al. BRAIN RESEARCH
- Neural progenitor cell transplantation promotes neuroprotection, enhances hippocampal neurogenesis, and improves cognitive outcomes after traumatic brain injury
- (2015) Meghan O. Blaya et al. EXPERIMENTAL NEUROLOGY
- Autologous Bone Marrow Mononuclear Cells Reduce Therapeutic Intensity for Severe Traumatic Brain Injury in Children*
- (2015) George P. Liao et al. Pediatric Critical Care Medicine
- Inflammatory reaction after traumatic brain injury: therapeutic potential of targeting cell–cell communication by chemokines
- (2015) Stefka Gyoneva et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Erythropoietin in traumatic brain injury: study protocol for a randomised controlled trial
- (2015) Alistair Nichol et al. Trials
- Statistical analysis plan for the Erythropoietin in Traumatic Brain Injury trial: a randomised controlled trial of erythropoietin versus placebo in moderate and severe traumatic brain injury
- (2015) Jeffrey Presneill et al. Trials
- Long-term atorvastatin treatment leads to alterations in behavior, cognition, and hippocampal biochemistry
- (2014) Jan M. Schilling et al. BEHAVIOURAL BRAIN RESEARCH
- Intranasal administration of plasmid DNA nanoparticles yields successful transfection and expression of a reporter protein in rat brain
- (2014) B T Harmon et al. GENE THERAPY
- Neuroprotective Strategies for Traumatic Brain Injury: Improving Clinical Translation
- (2014) Shruti Kabadi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The association of traumatic brain injury with rate of progression of cognitive and functional impairment in a population-based cohort of Alzheimer's disease: the Cache County dementia progression study by Gilbert et al. Late effects of traumatic brain injury on dementia progression
- (2014) David J. Sharp INTERNATIONAL PSYCHOGERIATRICS
- Repeated Mild Traumatic Brain Injury Causes Chronic Neuroinflammation, Changes in Hippocampal Synaptic Plasticity, and Associated Cognitive Deficits
- (2014) Stephanie L Aungst et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Traumatic brain injury enhances neuroinflammation and lesion volume in caveolin deficient mice
- (2014) Ingrid R Niesman et al. Journal of Neuroinflammation
- Serum neurofilament light chain is a biomarker of human spinal cord injury severity and outcome
- (2014) J. Kuhle et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Downregulation of miR-23a and miR-27a following Experimental Traumatic Brain Injury Induces Neuronal Cell Death through Activation of Proapoptotic Bcl-2 Proteins
- (2014) B. Sabirzhanov et al. JOURNAL OF NEUROSCIENCE
- The efficacy of erythropoietin in treating experimental traumatic brain injury: a systematic review of controlled trials in animal models
- (2014) Weijun Peng et al. JOURNAL OF NEUROSURGERY
- Magnetic micelles for DNA delivery to rat brains after mild traumatic brain injury
- (2014) Mahasweta Das et al. Nanomedicine-Nanotechnology Biology and Medicine
- Network dysfunction after traumatic brain injury
- (2014) David J. Sharp et al. Nature Reviews Neurology
- Stem cells in neuroinjury and neurodegenerative disorders: challenges and future neurotherapeutic prospects
- (2014) KevinK.W. Wang et al. Neural Regeneration Research
- UWA-121, a mixed dopamine and serotonin re-uptake inhibitor, enhances l-DOPA anti-parkinsonian action without worsening dyskinesia or psychosis-like behaviours in the MPTP-lesioned common marmoset
- (2014) Philippe Huot et al. NEUROPHARMACOLOGY
- Novel mGluR5 Positive Allosteric Modulator Improves Functional Recovery, Attenuates Neurodegeneration, and Alters Microglial Polarization after Experimental Traumatic Brain Injury
- (2014) David J. Loane et al. Neurotherapeutics
- Effect of risperidone on the fluoxetine-induced changes in extracellular dopamine, serotonin and noradrenaline in the rat frontal cortex
- (2014) Katarzyna Kamińska et al. Pharmacological Reports
- Blood brain barrier dysfunction and delayed neurological deficits in mild traumatic brain injury induced by blast shock waves
- (2014) Ashok K. Shetty et al. Frontiers in Cellular Neuroscience
- Recombinant Human Erythropoietin Improves the Neurofunctional Recovery of Rats Following Traumatic Brain Injury via an Increase in Circulating Endothelial Progenitor Cells
- (2014) Liang Wang et al. Translational Stroke Research
- Biology of adeno-associated viral vectors in the central nervous system
- (2014) Giridhar Murlidharan et al. Frontiers in Molecular Neuroscience
- PPAR Agonists as Therapeutics for CNS Trauma and Neurological Diseases
- (2013) Shweta Mandrekar-Colucci et al. ASN Neuro
- Interaction of membrane/lipid rafts with the cytoskeleton: Impact on signaling and function
- (2013) Brian P. Head et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Umbilical cord mesenchymal stem cell transplantation significantly improves neurological function in patients with sequelae of traumatic brain injury
- (2013) Sen Wang et al. BRAIN RESEARCH
- Neural Stem/Progenitor Cell Transplantation for Cortical Visual Impairment in Neonatal Brain Injured Patients
- (2013) Zuo Luan et al. CELL TRANSPLANTATION
- Targeting PPAR Isoforms Following CNS Injury
- (2013) Heather M. Yonutas et al. CURRENT DRUG TARGETS
- Induction of oxidative and nitrosative damage leads to cerebrovascular inflammation in an animal model of mild traumatic brain injury induced by primary blast
- (2013) P.M. Abdul-Muneer et al. FREE RADICAL BIOLOGY AND MEDICINE
- Phosphodiesterase Inhibition Rescues Chronic Cognitive Deficits Induced by Traumatic Brain Injury
- (2013) D. J. Titus et al. JOURNAL OF NEUROSCIENCE
- Maturation-dependent response of neurogenesis after traumatic brain injury in children
- (2013) Sabrina R. Taylor et al. Journal of Neurosurgery-Pediatrics
- Changes in the GEF-H1 Pathways after Traumatic Brain Injury
- (2013) Inna Sabirzhanova et al. JOURNAL OF NEUROTRAUMA
- Development, maintenance and disruption of the blood-brain barrier
- (2013) Birgit Obermeier et al. NATURE MEDICINE
- Acute and chronic traumatic encephalopathies: pathogenesis and biomarkers
- (2013) Steven T. DeKosky et al. Nature Reviews Neurology
- Biomarkers of mild traumatic brain injury in cerebrospinal fluid and blood
- (2013) Henrik Zetterberg et al. Nature Reviews Neurology
- Animal models of traumatic brain injury
- (2013) Ye Xiong et al. NATURE REVIEWS NEUROSCIENCE
- The Effect of HMG-CoA Reductase Inhibitors on Cognition in Patients With Alzheimer's Dementia: A Prospective Withdrawal and Rechallenge Pilot Study
- (2012) Kalpana P. Padala et al. American Journal Geriatric Pharmacotherapy
- Results of a phase II placebo-controlled randomized trial of minocycline in acute spinal cord injury
- (2012) Steven Casha et al. BRAIN
- Neuroinflammation after traumatic brain injury: Opportunities for therapeutic intervention
- (2012) Alok Kumar et al. BRAIN BEHAVIOR AND IMMUNITY
- Intranasal administration of nerve growth factor ameliorate β-amyloid deposition after traumatic brain injury in rats
- (2012) Lili Tian et al. BRAIN RESEARCH
- Intranasal delivery of nerve growth factor attenuates aquaporins-4-induced edema following traumatic brain injury in rats
- (2012) Qiushi Lv et al. BRAIN RESEARCH
- Mitochondria in traumatic brain injury and mitochondrial-targeted multipotential therapeutic strategies
- (2012) Gang Cheng et al. BRITISH JOURNAL OF PHARMACOLOGY
- Identification of Biologically Active PDE11-Selective Inhibitors Using a Yeast-Based High-Throughput Screen
- (2012) Ozge Ceyhan et al. CHEMISTRY & BIOLOGY
- Axonal pathology in traumatic brain injury
- (2012) Victoria E. Johnson et al. EXPERIMENTAL NEUROLOGY
- Adenylyl cyclase AC8 directly controls its micro-environment by recruiting the actin cytoskeleton in a cholesterol-rich milieu
- (2012) Laura J. Ayling et al. JOURNAL OF CELL SCIENCE
- Combination of Vascular Endothelial and Fibroblast Growth Factor 2 for Induction of Neurogenesis and Angiogenesis after Traumatic Brain Injury
- (2012) Orli Thau-Zuchman et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- New perspectives on central and peripheral immune responses to acute traumatic brain injury
- (2012) Mahasweta Das et al. Journal of Neuroinflammation
- Magnetic stimulation modulates structural synaptic plasticity and regulates BDNF–TrkB signal pathway in cultured hippocampal neurons
- (2012) Jun Ma et al. NEUROCHEMISTRY INTERNATIONAL
- Disruptions of functional connectivity in the default mode network of comatose patients
- (2012) L. Norton et al. NEUROLOGY
- Noninvasive Brain Stimulation to Modulate Neuroplasticity in Traumatic Brain Injury
- (2012) Mauricio Fernando Villamar et al. NEUROMODULATION
- Candesartan, an Angiotensin II AT1-Receptor Blocker and PPAR-γ Agonist, Reduces Lesion Volume and Improves Motor and Memory Function After Traumatic Brain Injury in Mice
- (2012) Sonia Villapol et al. NEUROPSYCHOPHARMACOLOGY
- Age-dependent alterations in cAMP signaling contribute to synaptic plasticity deficits following traumatic brain injury
- (2012) D.J. Titus et al. NEUROSCIENCE
- Effects of early rolipram treatment on histopathological outcome after controlled cortical impact injury in mice
- (2012) Coleen M. Atkins et al. NEUROSCIENCE LETTERS
- Salience network integrity predicts default mode network function after traumatic brain injury
- (2012) V. Bonnelle et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Axonal transport and neurodegenerative disease: Can we see the elephant?
- (2012) Lawrence S.B. Goldstein PROGRESS IN NEUROBIOLOGY
- Chronic Traumatic Encephalopathy in Blast-Exposed Military Veterans and a Blast Neurotrauma Mouse Model
- (2012) L. E. Goldstein et al. Science Translational Medicine
- A single mild fluid percussion injury induces short-term behavioral and neuropathological changes in the Long–Evans rat: Support for an animal model of concussion
- (2011) Sandy R. Shultz et al. BEHAVIOURAL BRAIN RESEARCH
- Harnessing neuroplasticity for clinical applications
- (2011) S. C. Cramer et al. BRAIN
- Recruitment of Actin Modifiers to TrkA Endosomes Governs Retrograde NGF Signaling and Survival
- (2011) Anthony W. Harrington et al. CELL
- Genetically modified human umbilical cord blood cells expressing vascular endothelial growth factor and fibroblast growth factor 2 differentiate into glial cells after transplantation into amyotrophic lateral sclerosis transgenic mice
- (2011) Albert A Rizvanov et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Neuron-targeted Caveolin-1 Protein Enhances Signaling and Promotes Arborization of Primary Neurons
- (2011) Brian P. Head et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The F-BAR domain protein PACSIN2 associates with Rac1 and regulates cell spreading and migration
- (2011) B.-J. de Kreuk et al. JOURNAL OF CELL SCIENCE
- Selective CDK Inhibitor Limits Neuroinflammation and Progressive Neurodegeneration after Brain Trauma
- (2011) Shruti V Kabadi et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- A mouse model of human repetitive mild traumatic brain injury
- (2011) Michael J. Kane et al. JOURNAL OF NEUROSCIENCE METHODS
- Pioglitazone Reduces Secondary Brain Damage after Experimental Brain Trauma by PPAR-γ-Independent Mechanisms
- (2011) Serge C. Thal et al. JOURNAL OF NEUROTRAUMA
- Repeated Mild Lateral Fluid Percussion Brain Injury in the Rat Causes Cumulative Long-Term Behavioral Impairments, Neuroinflammation, and Cortical Loss in an Animal Model of Repeated Concussion
- (2011) Sandy R. Shultz et al. JOURNAL OF NEUROTRAUMA
- Neural Stem Cells Over-Expressing Brain-Derived Neurotrophic Factor (BDNF) Stimulate Synaptic Protein Expression and Promote Functional Recovery Following Transplantation in Rat Model of Traumatic Brain Injury
- (2011) Haiying Ma et al. NEUROCHEMICAL RESEARCH
- Short-term administration of rhGH increases markers of cellular proliferation but not milk protein gene expression in normal lactating women
- (2011) Patricia D. Maningat et al. PHYSIOLOGICAL GENOMICS
- Pioglitazone attenuates mitochondrial dysfunction, cognitive impairment, cortical tissue loss, and inflammation following traumatic brain injury
- (2010) Andrew Sauerbeck et al. EXPERIMENTAL NEUROLOGY
- A Multi-Mode Shock Tube for Investigation of Blast-Induced Traumatic Brain Injury
- (2010) Dexter V. Reneer et al. JOURNAL OF NEUROTRAUMA
- Fluoxetine Increases Hippocampal Neurogenesis and Induces Epigenetic Factors But Does Not Improve Functional Recovery after Traumatic Brain Injury
- (2010) Yonggang Wang et al. JOURNAL OF NEUROTRAUMA
- Blood–brain barrier breakdown as a therapeutic target in traumatic brain injury
- (2010) Dan Shlosberg et al. Nature Reviews Neurology
- Randomized controlled trial of atorvastatin in mild to moderate Alzheimer disease: LEADe
- (2010) H. H. Feldman et al. NEUROLOGY
- Calpain as a therapeutic target in traumatic brain injury
- (2010) Kathryn E. Saatman et al. Neurotherapeutics
- PDE8 Regulates Rapid Teff Cell Adhesion and Proliferation Independent of ICER
- (2010) Amanda G. Vang et al. PLoS One
- Retrograde axonal transport: pathways to cell death?
- (2010) Eran Perlson et al. TRENDS IN NEUROSCIENCES
- The Growth Cone Cytoskeleton in Axon Outgrowth and Guidance
- (2010) E. W. Dent et al. Cold Spring Harbor Perspectives in Biology
- Rho and Ras GTPases in Axon Growth, Guidance, and Branching
- (2010) A. Hall et al. Cold Spring Harbor Perspectives in Biology
- Transcriptome Profiling Reveals TGF- Signaling Involvement in Epileptogenesis
- (2009) L. P. Cacheaux et al. JOURNAL OF NEUROSCIENCE
- cAMP-Dependent Axon Guidance Is Distinctly Regulated by Epac and Protein Kinase A
- (2009) A. J. Murray et al. JOURNAL OF NEUROSCIENCE
- Astrocytic Dysfunction in Epileptogenesis: Consequence of Altered Potassium and Glutamate Homeostasis?
- (2009) Y. David et al. JOURNAL OF NEUROSCIENCE
- Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord
- (2009) K. A. Kigerl et al. JOURNAL OF NEUROSCIENCE
- Repeated traumatic brain injury affects composite cognitive function in piglets
- (2009) Stuart H Friess et al. JOURNAL OF NEUROTRAUMA
- Structure and function of the blood–brain barrier
- (2009) N. Joan Abbott et al. NEUROBIOLOGY OF DISEASE
- Deficits in ERK and CREB activation in the hippocampus after traumatic brain injury
- (2009) Coleen M. Atkins et al. NEUROSCIENCE LETTERS
- Statin-Associated Adverse Cognitive Effects: Survey Results from 171 Patients
- (2009) Marcella A Evans et al. PHARMACOTHERAPY
- The blood–brain and the blood–cerebrospinal fluid barriers: function and dysfunction
- (2009) Britta Engelhardt et al. Seminars in Immunopathology
- PPARγ agonist rosiglitazone is neuroprotective after traumatic brain injury via anti-inflammatory and anti-oxidative mechanisms
- (2008) Jae-Hyuk Yi et al. BRAIN RESEARCH
- Caveolin-1 in cell polarization and directional migration
- (2008) A GRANDEGARCIA et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Tailoring the AAV vector capsid for gene therapy
- (2008) L H Vandenberghe et al. GENE THERAPY
- Roscovitine Reduces Neuronal Loss, Glial Activation, and Neurologic Deficits after Brain Trauma
- (2008) Genell D Hilton et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Blast-Induced Brain Injury and Posttraumatic Hypotension and Hypoxemia
- (2008) Douglas S. DeWitt et al. JOURNAL OF NEUROTRAUMA
- Astrocytes in the Epileptic Brain
- (2008) Jonathon Wetherington et al. NEURON
- A critical role for the right fronto-insular cortex in switching between central-executive and default-mode networks
- (2008) D. Sridharan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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