Neurovascular and Cognitive failure in Alzheimer’s Disease: Benefits of Cardiovascular Therapy
出版年份 2016 全文链接
标题
Neurovascular and Cognitive failure in Alzheimer’s Disease: Benefits of Cardiovascular Therapy
作者
关键词
Vascular oxidative stress, Cardiovascular therapy, Cerebrovascular reactivity, Memory pathways, Statin, Angiotensin receptor blocker
出版物
CELLULAR AND MOLECULAR NEUROBIOLOGY
Volume 36, Issue 2, Pages 219-232
出版商
Springer Nature
发表日期
2016-03-19
DOI
10.1007/s10571-015-0285-4
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Effects of Simvastatin on Cerebrospinal Fluid Biomarkers and Cognition in Middle-Aged Adults at Risk for Alzheimer's Disease
- (2017) Cynthia M. Carlsson et al. JOURNAL OF ALZHEIMERS DISEASE
- Neuroprotective Effects of Statins in an In Vitro Model of Alzheimer's Disease
- (2017) Ana Catarina R.G. Fonseca et al. JOURNAL OF ALZHEIMERS DISEASE
- Venular degeneration leads to vascular dysfunction in a transgenic model of Alzheimer’s disease
- (2015) Aaron Y. Lai et al. BRAIN
- HMG-CoA Reductase Inhibitors Bind to PPARα to Upregulate Neurotrophin Expression in the Brain and Improve Memory in Mice
- (2015) Avik Roy et al. Cell Metabolism
- Clearance systems in the brain—implications for Alzheimer disease
- (2015) Jenna M. Tarasoff-Conway et al. Nature Reviews Neurology
- Immunotherapeutic Approaches for Alzheimer’s Disease
- (2015) Thomas Wisniewski et al. NEURON
- Simvastatin prevents β-amyloid25–35-impaired neurogenesis in hippocampal dentate gyrus through α7nAChR-dependent cascading PI3K-Akt and increasing BDNF via reduction of farnesyl pyrophosphate
- (2015) Conghui Wang et al. NEUROPHARMACOLOGY
- The development of small molecule angiotensin IV analogs to treat Alzheimer's and Parkinson's diseases
- (2015) John W. Wright et al. PROGRESS IN NEUROBIOLOGY
- Neuroprotective Effects of Angiotensin Receptor Blockers
- (2014) Sonia Villapol et al. AMERICAN JOURNAL OF HYPERTENSION
- Cognitive Effects of Statin Medications
- (2014) Brendan J. Kelley et al. CNS DRUGS
- Impaired Cerebral Autoregulation and Vasomotor Reactivity in Sporadic Alzheimer’s Disease
- (2014) Aisha Abeelen et al. Current Alzheimer Research
- Inhibiting Geranylgeranylation Increases Neurite Branching and Differentially Activates Cofilin in Cell Bodies and Growth Cones
- (2014) Filsy Samuel et al. MOLECULAR NEUROBIOLOGY
- Vascular and parenchymal amyloid pathology in an Alzheimer disease knock-in mouse model: interplay with cerebral blood flow
- (2014) Hongmei Li et al. Molecular Neurodegeneration
- Angiotensin II type 1 receptor blocker losartan prevents and rescues cerebrovascular, neuropathological and cognitive deficits in an Alzheimer’s disease model
- (2014) Brice Ongali et al. NEUROBIOLOGY OF DISEASE
- Differential effects of angiotensin II receptor blockers on Aβ generation
- (2014) Junjun Liu et al. NEUROSCIENCE LETTERS
- Cardiovascular effects of statins, beyond lipid-lowering properties
- (2014) Christos G. Mihos et al. PHARMACOLOGICAL RESEARCH
- The key role of transient receptor potential melastatin-2 channels in amyloid-β-induced neurovascular dysfunction
- (2014) L. Park et al. Nature Communications
- Regional differences in the morphological and functional effects of aging on cerebral basement membranes and perivascular drainage of amyloid-β from the mouse brain
- (2013) Cheryl A. Hawkes et al. AGING CELL
- Endothelial TRPV4 channels mediate dilation of cerebral arteries: impairment and recovery in cerebrovascular pathologies related to Alzheimer's disease
- (2013) Luqing Zhang et al. BRITISH JOURNAL OF PHARMACOLOGY
- Current status of renin–aldosterone angiotensin system-targeting anti-hypertensive drugs as therapeutic options for Alzheimer's disease
- (2013) Emma Louise Ashby et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Cerebral Blood Flow Changes after Brain Injury in Human Amyloid-Beta Knock-in Mice
- (2013) Eric E Abrahamson et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Chronic Rapamycin Restores Brain Vascular Integrity and Function Through NO Synthase Activation and Improves Memory in Symptomatic Mice Modeling Alzheimer’s Disease
- (2013) Ai-Ling Lin et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Vascular Aspects of Cognitive Impairment and Dementia
- (2013) Maximilian Wiesmann et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Cognitive and cerebrovascular improvements following kinin B1 receptor blockade in Alzheimer’s disease mice
- (2013) Baptiste Lacoste et al. Journal of Neuroinflammation
- The Pathobiology of Vascular Dementia
- (2013) Costantino Iadecola NEURON
- Innate immunity receptor CD36 promotes cerebral amyloid angiopathy
- (2013) L. Park et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Neurovascular Dysfunction and Faulty Amyloid -Peptide Clearance in Alzheimer Disease
- (2013) A. P. Sagare et al. Cold Spring Harbor Perspectives in Medicine
- Impaired structural correlates of memory in Alzheimer's disease mice
- (2013) AmanPreet Badhwar et al. NeuroImage-Clinical
- Amyloid-β-dependent compromise of microvascular structure and function in a model of Alzheimer’s disease
- (2012) Adrienne Dorr et al. BRAIN
- Deficiency in Mural Vascular Cells Coincides with Blood-Brain Barrier Disruption in Alzheimer's Disease
- (2012) Jesse D. Sengillo et al. BRAIN PATHOLOGY
- Simvastatin attenuates axonal injury after experimental traumatic brain injury and promotes neurite outgrowth of primary cortical neurons
- (2012) Hongtao Wu et al. BRAIN RESEARCH
- Microvascular cerebral blood volume changes in aging APPswe/PS1dE9 AD mouse model: a voxel-wise approach
- (2012) Valerio Zerbi et al. Brain Structure & Function
- LRP1 in Brain Vascular Smooth Muscle Cells Mediates Local Clearance of Alzheimer's Amyloid-
- (2012) T. Kanekiyo et al. JOURNAL OF NEUROSCIENCE
- Age-Dependent Rescue by Simvastatin of Alzheimer's Disease Cerebrovascular and Memory Deficits
- (2012) X.-K. Tong et al. JOURNAL OF NEUROSCIENCE
- Cortical atrophy and hypoperfusion in a transgenic mouse model of Alzheimer's disease
- (2012) François Hébert et al. NEUROBIOLOGY OF AGING
- Atorvastatin and pitavastatin reduce senile plaques and inflammatory responses in a mouse model of Alzheimer’s disease
- (2012) Tomoko Kurata et al. NEUROLOGICAL RESEARCH
- The brain renin–angiotensin system: a diversity of functions and implications for CNS diseases
- (2012) John W. Wright et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Elementary Ca2+ Signals Through Endothelial TRPV4 Channels Regulate Vascular Function
- (2012) S. K. Sonkusare et al. SCIENCE
- Roles of Brain Angiotensin II in Cognitive Function and Dementia
- (2012) Masaki Mogi et al. International Journal of Hypertension
- Vascular β-amyloid and early astrocyte alterations impair cerebrovascular function and cerebral metabolism in transgenic arcAβ mice
- (2011) Mario Merlini et al. ACTA NEUROPATHOLOGICA
- Atorvastatin and pitavastatin protect cerebellar Purkinje cells in AD model mice and preserve the cytokines MCP-1 and TNF-α
- (2011) Miki Kozuki et al. BRAIN RESEARCH
- Identification and development of specific inhibitors for insulin-regulated aminopeptidase as a new class of cognitive enhancers
- (2011) Anthony L Albiston et al. BRITISH JOURNAL OF PHARMACOLOGY
- Neurovascular function in Alzheimer's disease patients and experimental models
- (2011) Nektaria Nicolakakis et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Impaired cerebral vasoreactivity to CO2 in Alzheimer's disease using BOLD fMRI
- (2011) S. Cantin et al. NEUROIMAGE
- Vascular risk factors promote conversion from mild cognitive impairment to Alzheimer disease
- (2011) J. Li et al. NEUROLOGY
- Simvastatin-mediated enhancement of long-term potentiation is driven by farnesyl-pyrophosphate depletion and inhibition of farnesylation
- (2011) R.A. Mans et al. NEUROSCIENCE
- Scavenger receptor CD36 is essential for the cerebrovascular oxidative stress and neurovascular dysfunction induced by amyloid-
- (2011) L. Park et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The overlap between neurodegenerative and vascular factors in the pathogenesis of dementia
- (2010) Costantino Iadecola ACTA NEUROPATHOLOGICA
- ASL Perfusion MRI Predicts Cognitive Decline and Conversion From MCI to Dementia
- (2010) Linda L. Chao et al. ALZHEIMER DISEASE & ASSOCIATED DISORDERS
- Atorvastatin and pitavastatin improve cognitive function and reduce senile plaque and phosphorylated tau in aged APP mice
- (2010) Tomoko Kurata et al. BRAIN RESEARCH
- Atorvastatin and Aβ(1–40): Not as Simple as Cholesterol Reduction in Brain and Relevance to Alzheimer Disease
- (2010) D. Allan Butterfield EXPERIMENTAL NEUROLOGY
- Neurite-like structures induced by mevalonate pathway blockade are due to the stability of cell adhesion foci and are enhanced by the presence of APP
- (2010) Mary Hughes et al. JOURNAL OF NEUROCHEMISTRY
- Age-Varying Association Between Statin Use and Incident Alzheimer's Disease
- (2010) Ge Li et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Forebrain-dominant deficit in cerebrovascular reactivity in Alzheimer's disease
- (2010) Uma S. Yezhuvath et al. NEUROBIOLOGY OF AGING
- Protective Effects of Intranasal Losartan in the APP/PS1 Transgenic Mouse Model of Alzheimer Disease
- (2010) Lusine Danielyan et al. REJUVENATION RESEARCH
- The neural correlates of verbal short-term memory in Alzheimer's disease: an fMRI study
- (2009) F. Peters et al. BRAIN
- Chronic cerebral hypoperfusion accelerates amyloid β deposition in APPSwInd transgenic mice
- (2009) Hiroshi Kitaguchi et al. BRAIN RESEARCH
- Anti-Inflammatory Effects of Angiotensin Receptor Blockers in the Brain and the Periphery
- (2009) Julius Benicky et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- The brain RAS and Alzheimer's disease
- (2009) John W. Wright et al. EXPERIMENTAL NEUROLOGY
- Prevention of dementia by antihypertensive drugs: how AT1-receptor-blockers and dihydropyridines better prevent dementia in hypertensive patients than thiazides and ACE-inhibitors
- (2009) Albert Fournier et al. Expert Review of Neurotherapeutics
- Cognitive Deficit in Amyloid-β–Injected Mice Was Improved by Pretreatment With a Low Dose of Telmisartan Partly Because of Peroxisome Proliferator-Activated Receptor-γ Activation
- (2009) Kana Tsukuda et al. HYPERTENSION
- Protein Kinase C-Inhibiting Properties of the Losartan Metabolite EXP3179 Make the Difference
- (2009) Philip Wenzel et al. HYPERTENSION
- Angiotensin Receptor Blocker Prevented β-Amyloid-Induced Cognitive Impairment Associated With Recovery of Neurovascular Coupling
- (2009) Shuko Takeda et al. HYPERTENSION
- The neural correlates of naming and fluency deficits in Alzheimer's disease: an FDG-PET study
- (2009) Rebecca J. Melrose et al. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
- The angiotensin AT4 receptor subtype as a target for the treatment of memory dysfunction associated with Alzheimer's disease
- (2009) John W Wright et al. JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM
- Simvastatin improves cerebrovascular function and counters soluble amyloid-beta, inflammation and oxidative stress in aged APP mice
- (2009) Xin-Kang Tong et al. NEUROBIOLOGY OF DISEASE
- Gene knockout of insulin-regulated aminopeptidase: Loss of the specific binding site for angiotensin IV and age-related deficit in spatial memory
- (2009) Anthony L. Albiston et al. NEUROBIOLOGY OF LEARNING AND MEMORY
- Categorical and correlational analyses of baseline fluorodeoxyglucose positron emission tomography images from the Alzheimer's Disease Neuroimaging Initiative (ADNI)
- (2009) Jessica B.S. Langbaum et al. NEUROIMAGE
- Treatment of vascular risk factors is associated with slower decline in Alzheimer disease
- (2009) Y. Deschaintre et al. NEUROLOGY
- Simvastatin enhances hippocampal long-term potentiation in C57BL/6 mice
- (2009) R.A. Mans et al. NEUROSCIENCE
- Angiotensins in Alzheimer's disease – friend or foe?
- (2009) Patrick G. Kehoe et al. TRENDS IN NEUROSCIENCES
- Telmisartan prevented cognitive decline partly due to PPAR-γ activation
- (2008) Masaki Mogi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Alzheimer’s disease, cerebrovascular dysfunction and the benefits of exercise: From vessels to neurons
- (2008) Christian Lange-Asschenfeldt et al. EXPERIMENTAL GERONTOLOGY
- Statins are associated with a reduced risk of Alzheimer disease regardless of lipophilicity. The Rotterdam Study
- (2008) M D M Haag et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Complete Rescue of Cerebrovascular Function in Aged Alzheimer's Disease Transgenic Mice by Antioxidants and Pioglitazone, a Peroxisome Proliferator-Activated Receptor Agonist
- (2008) N. Nicolakakis et al. JOURNAL OF NEUROSCIENCE
- Cerebrovascular Dysfunction in Amyloid Precursor Protein Transgenic Mice: Contribution of Soluble and Insoluble Amyloid- Peptide, Partial Restoration via -Secretase Inhibition
- (2008) B. H. Han et al. JOURNAL OF NEUROSCIENCE
- Simvastatin-Mediated Upregulation of VEGF and BDNF, Activation of the PI3K/Akt Pathway, and Increase of Neurogenesis Are Associated with Therapeutic Improvement after Traumatic Brain Injury
- (2008) Hongtao Wu et al. JOURNAL OF NEUROTRAUMA
- From angiotensin IV binding site to AT4 receptor
- (2008) Patrick M.L. Vanderheyden MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Use of statins and incidence of dementia and cognitive impairment without dementia in a cohort study
- (2008) C. Cramer et al. NEUROLOGY
- Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein
- (2008) L. Park et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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