Cell Transplantation and Neuroengineering Approach for Spinal Cord Injury Treatment: A Summary of Current Laboratory Findings and Review of Literature

Integration of donor mesenchymal stem cell-derived neuron-like cells into host neural network after rat spinal cord transection

(2015) Xiang Zeng et al.   BIOMATERIALS

Repair of spinal cord injury with neuronal relays: From fetal grafts to neural stem cells

(2015) Joseph F. Bonner et al.   BRAIN RESEARCH

Permissive Schwann Cell Graft/Spinal Cord Interfaces for Axon Regeneration

(2015) Ryan R. Williams et al.   CELL TRANSPLANTATION

A re-assessment of long distance growth and connectivity of neural stem cells after severe spinal cord injury

(2014) Kelli G. Sharp et al.   EXPERIMENTAL NEUROLOGY

AAVshRNA-Mediated Suppression of PTEN in Adult Rats in Combination with Salmon Fibrin Administration Enables Regenerative Growth of Corticospinal Axons and Enhances Recovery of Voluntary Motor Function after Cervical Spinal Cord Injury

(2014) G. Lewandowski et al.   JOURNAL OF NEUROSCIENCE

The integration of NSC-derived and host neural networks after rat spinal cord transection

(2013) Bi-Qin Lai et al.   BIOMATERIALS

Mesenchymal Stromal Cells: Sensors and Switchers of Inflammation

(2013) Maria Ester Bernardo et al.   Cell Stem Cell

A comparative study of gelatin sponge scaffolds and PLGA scaffolds transplanted to completely transected spinal cord of rat

(2013) Bao-ling Du et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Nerve Regeneration Restores Supraspinal Control of Bladder Function after Complete Spinal Cord Injury

(2013) Y.-S. Lee et al.   JOURNAL OF NEUROSCIENCE

A Novel Growth-Promoting Pathway Formed by GDNF-Overexpressing Schwann Cells Promotes Propriospinal Axonal Regeneration, Synapse Formation, and Partial Recovery of Function after Spinal Cord Injury

(2013) L.-X. Deng et al.   JOURNAL OF NEUROSCIENCE

Long-Distance Growth and Connectivity of Neural Stem Cells after Severe Spinal Cord Injury

(2012) Paul Lu et al.   CELL

Autologous mesenchymal stem cell–derived dopaminergic neurons function in parkinsonian macaques

(2012) Takuya Hayashi et al.   JOURNAL OF CLINICAL INVESTIGATION

Treatment of a Mouse Model of Spinal Cord Injury by Transplantation of Human Induced Pluripotent Stem Cell-Derived Long-Term Self-Renewing Neuroepithelial-Like Stem Cells

(2012) Yusuke Fujimoto et al.   STEM CELLS

Cograft of neural stem cells and schwann cells overexpressing TrkC and neurotrophin-3 respectively after rat spinal cord transection

(2011) Jun-Mei Wang et al.   BIOMATERIALS

Transplantation of artificial neural construct partly improved spinal tissue repair and functional recovery in rats with spinal cord transection

(2011) Bao-Ling Du et al.   BRAIN RESEARCH

Bone Marrow Mesenchymal Stem Cells in a Three-Dimensional Gelatin Sponge Scaffold Attenuate Inflammation, Promote Angiogenesis, and Reduce Cavity Formation in Experimental Spinal Cord Injury

(2011) Xiang Zeng et al.   CELL TRANSPLANTATION

Neurotrophin-3 Gene-Modified Schwann Cells Promote TrkC Gene-Modified Mesenchymal Stem Cells to Differentiate into Neuron-Like Cells in Poly(Lactic-Acid-Co-Glycolic Acid) Multiple-Channel Conduit

(2011) Yan-qing Zhang et al.   CELLS TISSUES ORGANS

A New Combined Therapeutic Strategy of Governor Vessel Electro-Acupuncture and Adult Stem Cell Transplantation Promotes the Recovery of Injured Spinal Cord

(2011) Z. Liu et al.   CURRENT MEDICINAL CHEMISTRY

GDNF modifies reactive astrogliosis allowing robust axonal regeneration through Schwann cell-seeded guidance channels after spinal cord injury

(2011) Ling-Xiao Deng et al.   EXPERIMENTAL NEUROLOGY

Grafted Neural Progenitors Integrate and Restore Synaptic Connectivity across the Injured Spinal Cord

(2011) J. F. Bonner et al.   JOURNAL OF NEUROSCIENCE

Grafted human-induced pluripotent stem-cell-derived neurospheres promote motor functional recovery after spinal cord injury in mice

(2011) S. Nori et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neurons derived from transplanted neural stem cells restore disrupted neuronal circuitry in a mouse model of spinal cord injury

(2010) Masahiko Abematsu et al.   JOURNAL OF CLINICAL INVESTIGATION

NT-3 gene modified Schwann cells promote TrkC gene modified mesenchymal stem cells to differentiate into neuron-like cells in vitro

(2009) Yan-Qing Zhang et al.   ANATOMICAL SCIENCE INTERNATIONAL

Synaptic transmission of neural stem cells seeded in 3-dimensional PLGA scaffolds

(2009) Yi Xiong et al.   BIOMATERIALS

Molecular targets for axon regeneration: focus on the intrinsic pathways

(2009) Simone Di Giovanni   EXPERT OPINION ON THERAPEUTIC TARGETS

Brain-derived neurotrophic factor facilitates maturation of mesenchymal stem cell-derived dopamine progenitors to functional neurons

(2009) Katarzyna A. Trzaska et al.   JOURNAL OF NEUROCHEMISTRY

Spinal Interneuron Axons Spontaneously Regenerate after Spinal Cord Injury in the Adult Feline

(2009) K. K. Fenrich et al.   JOURNAL OF NEUROSCIENCE

Muscle Injection of AAV-NT3 Promotes Anatomical Reorganization of CST Axons and Improves Behavioral Outcome following SCI

(2009) Jenny Fortun et al.   JOURNAL OF NEUROTRAUMA

Neurotrophin-3 improves retinoic acid-induced neural differentiation of skin-derived precursors through a p75NTR-dependent signaling pathway

(2009) Wei Zhang et al.   NEUROSCIENCE RESEARCH

Current tissue engineering and novel therapeutic approaches to axonal regeneration following spinal cord injury using polymer scaffolds

(2009) Nicolas N. Madigan et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Manufacture of PLGA Multiple-Channel Conduits with Precise Hierarchical Pore Architectures and In Vitro/Vivo Evaluation for Spinal Cord Injury

(2009) Liumin He et al.   TISSUE ENGINEERING PART C-METHODS

IGF-I gene delivery promotes corticospinal neuronal survival but not regeneration after adult CNS injury

(2008) Edmund R. Hollis et al.   EXPERIMENTAL NEUROLOGY

p75 Neurotrophin Receptor Mediates Neuronal Cell Death by Activating GIRK Channels through Phosphatidylinositol 4,5-Bisphosphate

(2008) E. J. Coulson et al.   JOURNAL OF NEUROSCIENCE

Recovery of supraspinal control of stepping via indirect propriospinal relay connections after spinal cord injury

(2007) Gregoire Courtine et al.   NATURE MEDICINE