PTEN regulates PLK1 and controls chromosomal stability during cell division

Genome maintenance in the context of 4D chromatin condensation

(2016) Sonia Yu et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Nuclear PTEN tumor-suppressor functions through maintaining heterochromatin structure

(2015) Lili Gong et al.   CELL CYCLE

PTEN regulates DNA replication progression and stalled fork recovery

(2015) Jinxue He et al.   Nature Communications

PTEN stabilizes TOP2A and regulates the DNA decatenation

(2015) Xi Kang et al.   Scientific Reports

Plk1 Protein Phosphorylates Phosphatase and Tensin Homolog (PTEN) and Regulates Its Mitotic Activity during the Cell Cycle

(2014) Byeong Hyeok Choi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plk1 Phosphorylation of PTEN Causes a Tumor-Promoting Metabolic State

(2014) Z. Li et al.   MOLECULAR AND CELLULAR BIOLOGY

PTEN Interacts with Histone H1 and Controls Chromatin Condensation

(2014) Zhu Hong Chen et al.   Cell Reports

PTEN C-Terminal Deletion Causes Genomic Instability and Tumor Development

(2014) Zhuo Sun et al.   Cell Reports

Nuclear PTEN Controls DNA Repair and Sensitivity to Genotoxic Stress

(2013) C. Bassi et al.   SCIENCE

Regulatory modules: Coupling protein stability to phopshoregulation during cell division

(2012) Liam J. Holt   FEBS LETTERS

PTEN Protein Phosphatase Activity Correlates with Control of Gene Expression and Invasion, a Tumor-Suppressing Phenotype, But Not with AKT Activity

(2012) P. Tibarewal et al.   Science Signaling

Reduction ofPtendose leads to neoplastic development in multiple organs ofPtenshRNAmice

(2011) Hong Shen-Li et al.   CANCER BIOLOGY & THERAPY

CREB Is a Novel Nuclear Target of PTEN Phosphatase

(2011) T. Gu et al.   CANCER RESEARCH

Nuclear PTEN Regulates the APC-CDH1 Tumor-Suppressive Complex in a Phosphatase-Independent Manner

(2011) Min Sup Song et al.   CELL

Polo-like Kinase 1 Facilitates Loss of Pten Tumor Suppressor-induced Prostate Cancer Formation

(2011) X. Shawn Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Suppression of leukemia development caused by PTEN loss

(2011) W. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody

(2010) Antonia P. Sagona et al.   NATURE CELL BIOLOGY

Subtle variations in Pten dose determine cancer susceptibility

(2010) Andrea Alimonti et al.   NATURE GENETICS

Evidence that Mitotic Exit Is a Better Cancer Therapeutic Target Than Spindle Assembly

(2009) Hsiao-Chun Huang et al.   CANCER CELL

Assessment of the Mitotic Spindle Assembly Checkpoint (SAC) as the Target of Anticancer Therapies

(2009) Victor Bolanos-Garcia   CURRENT CANCER DRUG TARGETS

PTEN and the PI3-Kinase Pathway in Cancer

(2008) Nader Chalhoub et al.   Annual Review of Pathology-Mechanisms of Disease

Acetylation Is Indispensable for p53 Activation

(2008) Yi Tang et al.   CELL

Integrative Genomic Analysis of Aneuploidy in Uveal Melanoma

(2008) J. P. Ehlers et al.   CLINICAL CANCER RESEARCH

Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation

(2008) Wei Guo et al.   NATURE

Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery

(2008) Libor Macůrek et al.   NATURE

PTEN: a new guardian of the genome

(2008) Y Yin et al.   ONCOGENE

Bora and the Kinase Aurora A Cooperatively Activate the Kinase Plk1 and Control Mitotic Entry

(2008) A. Seki et al.   SCIENCE