Asymmetric Synthesis of Chiral Chromanes by Copper‐Catalyzed Hydroamination of 2 H ‐Chromenes

Cu(I)-Catalyzed Enantioselective Alkynylation of Thiochromones

(2020) Ling Meng et al.   ORGANIC LETTERS

Catalytic Asymmetric Synthesis of α-Arylpyrrolidines and Benzo-fused Nitrogen Heterocycles

(2019) Xi-Jie Dai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

CuH-Catalyzed Enantioselective Alkylation of Indole Derivatives with Ligand-Controlled Regiodivergence

(2019) Yuxuan Ye et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Kinetic Resolution and Dynamic Kinetic Resolution of Chromene by Rhodium-Catalyzed Asymmetric Hydroarylation

(2019) Qingjing Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regio- and Enantioselective Formal Hydroamination of Enamines for the Synthesis of 1,2-Diamines

(2019) Lu Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regio- and Enantioselective Synthesis of 1,2-Diamine Derivatives by Copper-Catalyzed Hydroamination

(2019) Saki Ichikawa et al.   ORGANIC LETTERS

Synthesis of α-Trifluoromethylamines by Cu-Catalyzed Regio- and Enantioselective Hydroamination of 1-Trifluoromethylalkenes

(2019) Tatsuaki Takata et al.   ORGANIC LETTERS

Copper-Catalyzed Asymmetric Hydroboration of 2H-Chromenes Using a Chiral Diphosphine Ligand

(2019) Xiufen Li et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Synthesis of 4-Aminotetrahydroquinolines via 1,2-Reductive Dearomatization of Quinolines and Copper(I) Hydride-Catalyzed Asymmetric Hydroamination

(2019) Qing-Feng Xu-Xu et al.   ORGANIC LETTERS

Enantioselective Dicarbofunctionalization of Unactivated Alkenes by Palladium-Catalyzed Tandem Heck/Suzuki Coupling Reaction

(2019) Zhan-Ming Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Synthesis of γ-Amino Alcohols by Copper-Catalyzed Hydroamination

(2019) Saki Ichikawa et al.   ORGANIC LETTERS

Diastereo- and Enantioselective CuH-Catalyzed Hydroamination of Strained Trisubstituted Alkenes

(2019) Sheng Feng et al.   ACS Catalysis

A Modified System for the Synthesis of Enantioenriched N -Arylamines through Copper-Catalyzed Hydroamination

(2018) Saki Ichikawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of α-Aminophosphines by Copper-Catalyzed Regioselective Hydroamination of Vinylphosphines

(2018) Tatsuaki Takata et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Halo-oxy- and Halo-azacyclizations Induced by Chiral Amidophosphate Catalysts and Halo-Lewis Acids

(2018) Yanhui Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric [4+2] Cyclization of para -Quinone Methide Derivatives with 3-Alkyl-2-vinylindoles

(2018) Xiao-Li Jiang et al.   ADVANCED SYNTHESIS & CATALYSIS

Copper-Catalyzed Ring Opening of Benzofurans and Enantioselective Hydroamination Cascade

(2018) Shuli You et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Advances in Hydrometallation of Alkenes and Alkynes via the First Row Transition Metal Catalysis

(2018) Jianhui Chen et al.   CHINESE JOURNAL OF CHEMISTRY

Mechanistically Guided Design of Ligands that Significantly Improve the Efficiency of CuH-Catalyzed Hydroamination Reactions

(2018) Andy A Thomas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development of New C-N and C-P Bond Formations with Alkenes and Alkynes Based on Electrophilic Amination and Phosphination

(2018) Koji Hirano et al.   JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN

A Practical Electrophilic Nitrogen Source for the Synthesis of Chiral Primary Amines by Copper-Catalyzed Hydroamination

(2018) Sheng Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Copper-Catalyzed Hydroamination of Vinylarenes with Anthranils

(2018) Fang Xie et al.   ORGANIC LETTERS

CuH-Catalyzed Regioselective Intramolecular Hydroamination for the Synthesis of Alkyl-Substituted Chiral Aziridines

(2017) Haoxuan Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ligand–Substrate Dispersion Facilitates the Copper-Catalyzed Hydroamination of Unactivated Olefins

(2017) Gang Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iridium-Catalyzed Asymmetric Hydrogenation of 2H-Chromenes: A Highly Enantioselective Approach to Isoflavan Derivatives

(2017) Jingzhao Xia et al.   ORGANIC LETTERS

MOF-derived cobalt nanoparticles catalyze a general synthesis of amines

(2017) Rajenahally V. Jagadeesh et al.   SCIENCE

The development and mechanistic investigation of a palladium-catalyzed 1,3-arylfluorination of chromenes

(2017) Richard T. Thornbury et al.   Chemical Science

Ruthenium-Catalyzed Dynamic Kinetic Resolution Asymmetric Transfer Hydrogenation of β-Chromanones by an Elimination-Induced Racemization Mechanism

(2017) Eric R. Ashley et al.   ACS Catalysis

Asymmetric synthesis of chromans via the Friedel–Crafts alkylation–hemiketalization catalysed by an N,N′-dioxide scandium(iii) complex

(2017) Xiaoyu Hao et al.   Organic Chemistry Frontiers

Synthesis of Chiral 1,4-Benzodioxanes and Chromans by Enantioselective Palladium-Catalyzed Alkene Aryloxyarylation Reactions

(2016) Naifu Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Domino Oxa-Michael/1,6-Addition Reactions: Asymmetric Synthesis of Chromans Bearing Oxindole Scaffolds

(2016) Kun Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synergistic Rhodium/Phosphoric Acid Catalysis for the Enantioselective Addition of Oxonium Ylides to ortho -Quinone Methides

(2016) Santosh Kumar Alamsetti et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Primary Amine Catalyzed Asymmetric α-Benzylation with In Situ Generatedortho-Quinone Methides

(2016) Yunbo Zhu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Evaluation of Chromane-Based Bryostatin Analogues Prepared via Hydrogen-Mediated C–C Bond Formation: Potency Does Not Confer Bryostatin-like Biology

(2016) John M. Ketcham et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-catalysed enantioselective stereodivergent synthesis of amino alcohols

(2016) Shi-Liang Shi et al.   NATURE

A direct approach to amines with remote stereocentres by enantioselective CuH-catalysed reductive relay hydroamination

(2016) Shaolin Zhu et al.   Nature Chemistry

Rh-Catalyzed Conjugate Addition of Arylzinc Chlorides to Thiochromones: A Highly Enantioselective Pathway for Accessing Chiral Thioflavanones

(2016) Ling Meng et al.   ORGANIC LETTERS

Regioselective, Asymmetric Formal Hydroamination of Unactivated Internal Alkenes

(2015) Yumeng Xi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Asymmetric 1,6-Addition/1,4-Addition Sequence to 2,4-Dienals for the Synthesis of Chiral Chromans

(2015) Pernille H. Poulsen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper Hydride Catalyzed Hydroamination of Alkenes and Alkynes

(2015) Michael T. Pirnot et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Inverse-Electron-Demand Oxa-Diels-Alder Reaction of In Situ Generatedortho-Quinone Methides with 3-Methyl-2-Vinylindoles

(2015) Jia-Jia Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium/Chiral Diene-Catalyzed Asymmetric 1,4-Addition of Arylboronic Acids to Chromones: A Highly Enantioselective Pathway for Accessing Chiral Flavanones

(2015) Qijie He et al.   Chemistry-An Asian Journal

Enantioselective Synthesis of Highly Substituted Chromans via the Oxa-Michael–Michael Cascade Reaction with a Bifunctional Organocatalyst

(2015) Prasenjit Saha et al.   JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Allylic C–H Oxidation for the Synthesis of Chromans

(2015) Pu-Sheng Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Synthesis of α-Aminoboronic Acid Derivatives by Copper-Catalyzed Enantioselective Hydroamination

(2015) Daiki Nishikawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Design of Modified Amine Transfer Reagents Allows the Synthesis of α-Chiral Secondary Amines via CuH-Catalyzed Hydroamination

(2015) Dawen Niu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic asymmetric hydroamination of unactivated internal olefins to aliphatic amines

(2015) Y. Yang et al.   SCIENCE

Enantioselective Synthesis of α-Aminosilanes by Copper-Catalyzed Hydroamination of Vinylsilanes

(2014) Nootaree Niljianskul et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Gold-Catalyzed Asymmetric Allylic Substitution of Free Alcohols: An Enantioselective Approach to Chiral Chromans with Quaternary Stereocenters for the Synthesis of Vitamin E and Analogues

(2014) Uxue Uria et al.   CHEMISTRY-A EUROPEAN JOURNAL

Microwave-Enhanced Asymmetric Transfer Hydrogenation ofN-(tert-Butylsulfinyl)imines

(2014) Óscar Pablo et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Enantioselective CuH-Catalyzed Anti-Markovnikov Hydroamination of 1,1-Disubstituted Alkenes

(2014) Shaolin Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Indium-Mediated Asymmetric Intramolecular Allenylation of N-tert-Butanesulfinyl Imines: Efficient and Practical Access to Chiral 3-Allenyl-4-aminochromanes

(2014) Lin Su et al.   ORGANIC LETTERS

Copper-Catalyzed Enantioselective Formal Hydroamination of Oxa- and Azabicyclic Alkenes with Hydrosilanes and Hydroxylamines

(2014) Yuya Miki et al.   ORGANIC LETTERS

High-turnover hypoiodite catalysis for asymmetric synthesis of tocopherols

(2014) M. Uyanik et al.   SCIENCE

Copper-Catalyzed Intermolecular Regioselective Hydroamination of Styrenes with Polymethylhydrosiloxane and Hydroxylamines

(2013) Yuya Miki et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalyzed Michael–Michael Cascade Reaction: Asymmetric Synthesis of Polysubstituted Chromans

(2013) Zhen-Xin Jia et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantio- and Regioselective CuH-Catalyzed Hydroamination of Alkenes

(2013) Shaolin Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd-Catalyzed Desymmetric Intramolecular O-Arylation Reaction: Enantioselective Synthesis of (3,4-Dihydro-2H-chromen-3-yl)methanols

(2013) Wenqiang Yang et al.   ORGANIC LETTERS

A Versatile Ru Catalyst for the Asymmetric Transfer Hydrogenation of Both Aromatic and Aliphatic Sulfinylimines

(2012) Óscar Pablo et al.   CHEMISTRY-A EUROPEAN JOURNAL

Palladium(II)-Catalyzed Enantioselective Synthesis of 2-Vinyl Oxygen Heterocycles

(2012) Jeffrey S. Cannon et al.   JOURNAL OF ORGANIC CHEMISTRY

Pd(II)-catalyzed asymmetric Wacker-type cyclization for the preparation of 2-vinylchroman derivatives with biphenyl tetraoxazoline ligands

(2012) Qingchuan Liu et al.   TETRAHEDRON

Highly enantioselective Friedel–Crafts alkylation reaction catalyzed by rosin-derived tertiary amine–thiourea: synthesis of modified chromanes with anticancer potency

(2011) Xianxing Jiang et al.   CHEMICAL COMMUNICATIONS

Catalytic Asymmetric Aza-Michael−Michael Addition Cascade: Enantioselective Synthesis of Polysubstituted 4-Aminobenzopyrans

(2011) Xu-Fan Wang et al.   ORGANIC LETTERS

Organocatalytic Asymmetric Sulfa-Michael/Michael Addition Reactions: A Strategy for the Synthesis of Highly Substituted Chromans with a Quaternary Stereocenter

(2010) Xu-Fan Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Synthesis of Chiral Primary Amines by Transfer Hydrogenation ofN-(tert-Butanesulfinyl)ketimines§

(2010) David Guijarro et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Total Synthesis of (+)-Conicol via Cascade Three-Component Organocatalysis

(2010) Bor-Cherng Hong et al.   ORGANIC LETTERS

Phosphine-Catalyzed Enantioselective Synthesis of Oxygen Heterocycles

(2009) Ying Kit Chung et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Efficient Boron−Copper Additions to Aryl-Substituted Alkenes Promoted by NHC−Based Catalysts. Enantioselective Cu-Catalyzed Hydroboration Reactions

(2009) Yunmi Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric oxa-Michael−Michael Cascade for Facile Construction of Chiral Chromans via an Aminal Intermediate

(2009) Liansuo Zu et al.   ORGANIC LETTERS

Asymmetric synthesis of chiral chromans

(2009) Hong C. Shen   TETRAHEDRON

Sulfoxide-Directed Stereocontrolled Access to 2H-Chromans: Total Synthesis of the (S,R,R,R)-Enantiomer of the Antihypertensive Drug Nebivolol

(2008) M. Carmen Carreño et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

BF3·Et2O-Mediated Cascade Cyclizations: Synthesis of Schweinfurthins F and G

(2008) Nolan R. Mente et al.   JOURNAL OF ORGANIC CHEMISTRY

Traceless Stereoinduction in the One-Pot Assembly of All Three Rings of Hexahydrodibenzopyrans

(2008) Keith A. Korthals et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Metal-Mediated Cyclization of Aryl and Benzyl Glycidyl Ethers: A Complete Scenario

(2008) Rocío Marcos et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ruthenium-Catalyzed Enantioselective Carbon−Carbon Bond Forming Reaction via Allenylidene-Ene Process: Synthetic Approach to Chiral Heterocycles Such As Chromane, Thiochromane, and 1,2,3,4-Tetrahydroquinoline Derivatives

(2008) Koji Fukamizu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diastereoselective Synthesis of α-Tocopherol: A New Concept for the Formation of Chromanols

(2008) Julien Chapelat et al.   ORGANIC LETTERS

Stereoselective Total Synthesis of (−)-Perrottetinene and Assignment of Its Absolute Configuration

(2007) Yanling Song et al.   ORGANIC LETTERS