Epigenetic dynamics in cancer stem cell dormancy

Epigenetic mechanism and target therapy of UHRF1 protein complex in malignancies

(2019) Busheng Xue et al.   OncoTargets and Therapy

PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications

(2019) Pramod Darvin et al.   Journal of Oncology

Methyl Donor Micronutrients that Modify DNA Methylation and Cancer Outcome

(2019) Abeer Mahmoud et al.   Nutrients

Exosomes from differentially activated macrophages influence dormancy or resurgence of breast cancer cells within bone marrow stroma

(2019) Nykia D. Walker et al.   Cell Death & Disease

Overview of DNA methylation in adult diffuse gliomas

(2019) Kosuke Aoki et al.   Brain Tumor Pathology

Epigenetic downregulation of TET3 reduces genome‐wide 5hmC levels and promotes glioblastoma tumorigenesis

(2019) Antonella Carella et al.   INTERNATIONAL JOURNAL OF CANCER

Gene promoter methylation and cancer: An umbrella review

(2019) Emmanouil Bouras et al.   GENE

Gap Junction Intercellular Communication in the Carcinogenesis Hallmarks: Is This a Phenomenon or Epiphenomenon?

(2019) Zefferino et al.   Cells

Acceleration in the DNA methylation age in breast cancer tumours from very young women

(2019) Sara S. Oltra et al.   Scientific Reports

Evaluation of Combination Treatment Effect With TRAIL-secreting Mesenchymal Stem Cells and Compound C Against Glioblastoma

(2019) HYE RIM HAN et al.   ANTICANCER RESEARCH

Causes of death after breast cancer diagnosis: A US population‐based analysis

(2019) Ahmed M. Afifi et al.   CANCER

DNA Modification Readers and Writers and Their Interplay

(2019) Cathia Rausch et al.   JOURNAL OF MOLECULAR BIOLOGY

Real-Time Sensing of TET2-Mediated DNA Demethylation In Vitro by Metal–Organic Framework-Based Oxygen Sensor for Mechanism Analysis and Stem-Cell Behavior Prediction

(2018) Yuzhi Xu et al.   ANALYTICAL CHEMISTRY

Secretome within the bone marrow microenvironment: A basis for mesenchymal stem cell treatment and role in cancer dormancy

(2018) Hussam S. Eltoukhy et al.   BIOCHIMIE

TET1-mediated hypomethylation activates oncogenic signaling in triple-negative breast cancer

(2018) Charly Ryan Good et al.   CANCER RESEARCH

Oxygen-induced alterations in the expression of chromatin modifying enzymes and the transcriptional regulation of imprinted genes

(2018) William M. Skiles et al.   GENE EXPRESSION PATTERNS

The Complex Subtype-Dependent Role of Connexin 43 (GJA1) in Breast Cancer

(2018) Mélanie Busby et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Intermittent hypoxia induces a metastatic phenotype in breast cancer

(2018) Anna Chen et al.   ONCOGENE

Human microRNAs preferentially target genes with intermediate levels of expression and its formation by mammalian evolution

(2018) Hisakazu Iwama et al.   PLoS One

Modulating the expression of Chtop, a versatile regulator of gene-specific transcription and mRNA export

(2018) Keiichi Izumikawa et al.   RNA Biology

Vitamin C in Stem Cell Reprogramming and Cancer

(2018) Luisa Cimmino et al.   TRENDS IN CELL BIOLOGY

Heritable DNA methylation marks associated with susceptibility to breast cancer

(2018) Jihoon E. Joo et al.   Nature Communications

Epigenetic dysregulation of TET2 in human glioblastoma

(2018) María G. García et al.   Oncotarget

Vitamin C promotes apoptosis in breast cancer cells by increasing TRAIL expression

(2018) David W. Sant et al.   Scientific Reports

Specific or not specific recruitment of DNMTs for DNA methylation, an epigenetic dilemma

(2018) Eric Hervouet et al.   Clinical Epigenetics

Immunity drives TET1 regulation in cancer through NF-κB

(2018) Evelyne Collignon et al.   Science Advances

Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate

(2018) Jose Luis Sardina et al.   Cell Stem Cell

TET2 controls chemoresistant slow-cycling cancer cell survival and tumor recurrence

(2018) Isabel Puig et al.   JOURNAL OF CLINICAL INVESTIGATION

The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space

(2018) Johanna Klughammer et al.   NATURE MEDICINE

DNA Methyltransferase Inhibitors and Their Therapeutic Potential

(2018) Zehao Zhou et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Polyamine Metabolism and Gene Methylation in Conjunction with One-Carbon Metabolism

(2018) Kuniyasu Soda   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

TET2 coactivates gene expression through demethylation of enhancers

(2018) Lu Wang et al.   Science Advances

Cancer Connectors: Connexins, Gap Junctions, and Communication

(2018) Maksim Sinyuk et al.   Frontiers in Oncology

Elevated FOXG1 and SOX2 in glioblastoma enforces neural stem cell identity through transcriptional control of cell cycle and epigenetic regulators

(2017) Harry Bulstrode et al.   GENES & DEVELOPMENT

Clinical significance of miRNA host gene promoter methylation in prostate cancer

(2017) Kristina Daniunaite et al.   HUMAN MOLECULAR GENETICS

Drug Resistance Driven by Cancer Stem Cells and Their Niche

(2017) Marta Prieto-Vila et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Interplay between the miRNome and the epigenetic machinery: Implications in health and disease

(2017) Shagun Poddar et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Regulation of human glioma cell apoptosis and invasion by miR-152-3p through targeting DNMT1 and regulating NF2

(2017) Jin Sun et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Mesenchymal stem cells: key players in cancer progression

(2017) Sarah M. Ridge et al.   Molecular Cancer

The Pluripotent Stem-Cell Marker Alkaline Phosphatase is Highly Expressed in Refractory Glioblastoma with DNA Hypomethylation

(2017) Yasuo Iwadate et al.   NEUROSURGERY

A novel requirement for DROSHA in maintenance of mammalian CG methylation

(2017) Athanasia Stathopoulou et al.   NUCLEIC ACIDS RESEARCH

A novel isoform of TET1 that lacks a CXXC domain is overexpressed in cancer

(2017) Charly R. Good et al.   NUCLEIC ACIDS RESEARCH

Methyl-CpG binding domain protein 1 regulates localization and activity of Tet1 in a CXXC3 domain-dependent manner

(2017) Peng Zhang et al.   NUCLEIC ACIDS RESEARCH

Retinoic acid directs breast cancer cell state changes through regulation of TET2-PKCζ pathway

(2017) M-J Wu et al.   ONCOGENE

Histone modifications: A review about the presence of this epigenetic phenomenon in carcinogenesis

(2017) Emanuely Silva Chrun et al.   PATHOLOGY RESEARCH AND PRACTICE

Epigenetic plasticity and the hallmarks of cancer

(2017) William A. Flavahan et al.   SCIENCE

Hypoxia-Mediated Epigenetic Regulation of Stemness in Brain Tumor Cells

(2017) Pankaj Prasad et al.   STEM CELLS

miRNA-148a regulates the expression of the estrogen receptor through DNMT1-mediated DNA methylation in breast cancer cells

(2017) Yurui Xu et al.   Oncology Letters

DNA methylation at enhancers identifies distinct breast cancer lineages

(2017) Thomas Fleischer et al.   Nature Communications

Role of UHRF1 in de novo DNA methylation in oocytes and maintenance methylation in preimplantation embryos

(2017) Shoji Maenohara et al.   PLoS Genetics

Lysine demethylase KDM2A inhibits TET2 to promote DNA methylation and silencing of tumor suppressor genes in breast cancer

(2017) J-Y Chen et al.   Oncogenesis

Niche heterogeneity in the bone marrow

(2016) Alexander Birbrair et al.   Annals of the New York Academy of Sciences

MicroRNA epigenetic signatures in human disease

(2016) Klara Piletič et al.   ARCHIVES OF TOXICOLOGY

Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2

(2016) Satoshi Inoue et al.   CANCER CELL

Mesenchymal Stem Cell–Derived Exosomes Stimulate Cycling Quiescence and Early Breast Cancer Dormancy in Bone Marrow

(2016) Sarah A. Bliss et al.   CANCER RESEARCH

Editing DNA Methylation in the Mammalian Genome

(2016) X. Shawn Liu et al.   CELL

Role of TET enzymes in DNA methylation, development, and cancer

(2016) Kasper Dindler Rasmussen et al.   GENES & DEVELOPMENT

Targeting cancer stem-like cells in glioblastoma and colorectal cancer through metabolic pathways

(2016) U.D. Kahlert et al.   INTERNATIONAL JOURNAL OF CANCER

5-Hydroxymethylcytosine expression is associated with poor survival in cervical squamous cell carcinoma

(2016) Li-Ying Zhang et al.   JAPANESE JOURNAL OF CLINICAL ONCOLOGY

Tumour hypoxia causes DNA hypermethylation by reducing TET activity

(2016) Bernard Thienpont et al.   NATURE

Allosteric control of mammalian DNA methyltransferases – a new regulatory paradigm

(2016) Albert Jeltsch et al.   NUCLEIC ACIDS RESEARCH

Binding of MBD proteins to DNA blocks Tet1 function thereby modulating transcriptional noise

(2016) Anne K. Ludwig et al.   NUCLEIC ACIDS RESEARCH

Human DNMT1 transition state structure

(2016) Quan Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TET enzymes as oxygen-dependent tumor suppressors: exciting new avenues for cancer management

(2016) Bernard Thienpont et al.   Epigenomics

Downregulation of TLX induces TET3 expression and inhibits glioblastoma stem cell self-renewal and tumorigenesis

(2016) Qi Cui et al.   Nature Communications

5-Hydroxymethylcytosine localizes to enhancer elements and is associated with survival in glioblastoma patients

(2016) Kevin C. Johnson et al.   Nature Communications

Oncogenic EGFR Represses the TET1 DNA Demethylase to Induce Silencing of Tumor Suppressors in Cancer Cells

(2016) Matteo Forloni et al.   Cell Reports

Emerging Molecular and Biological Functions of MBD2, a Reader of DNA Methylation

(2016) Kathleen H. Wood et al.   Frontiers in Genetics

Hypoxia, Epithelial-Mesenchymal Transition, and TET-Mediated Epigenetic Changes

(2016) Shih-Han Kao et al.   Journal of Clinical Medicine

DNMT1 and EZH2 mediated methylation silences the microRNA-200b/a/429 gene and promotes tumor progression

(2015) Xianghong Ning et al.   CANCER LETTERS

Hypoxia Drives Breast Tumor Malignancy through a TET–TNFα–p38–MAPK Signaling Axis

(2015) Min-Zu Wu et al.   CANCER RESEARCH

Altering TET dioxygenase levels within physiological range affects DNA methylation dynamics of HEK293 cells

(2015) Christian Grosser et al.   Epigenetics

Cancer stem cells in glioblastoma

(2015) Justin D. Lathia et al.   GENES & DEVELOPMENT

An Epigenetic Regulator: Methyl-CpG-Binding Domain Protein 1 (MBD1)

(2015) Lu Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MicroRNA-31 Is a Transcriptional Target of Histone Deacetylase Inhibitors and a Regulator of Cellular Senescence

(2015) Joon-Ho Cho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes

(2015) Tuomas Laukka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Global DNA Methylation Signatures in Glioblastoma-Derived Cancer Stem Cells

(2015) Eun-Joon Lee et al.   Journal of Genetics and Genomics

Engineering of a Histone-Recognition Domain in Dnmt3a Alters the Epigenetic Landscape and Phenotypic Features of Mouse ESCs

(2015) Kyung-Min Noh et al.   MOLECULAR CELL

Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex

(2015) Lanfeng Wang et al.   NATURE

Insulator dysfunction and oncogene activation in IDH mutant gliomas

(2015) William A. Flavahan et al.   NATURE

MicroRNA-29b/Tet1 regulatory axis epigenetically modulates mesendoderm differentiation in mouse embryonic stem cells

(2015) Jiajie Tu et al.   NUCLEIC ACIDS RESEARCH

LASP-1: a nuclear hub for the UHRF1-DNMT1-G9a-Snail1 complex

(2015) N Duvall-Noelle et al.   ONCOGENE

Reduced Expression of TET1, TET2, TET3 and TDG mRNAs Are Associated with Poor Prognosis of Patients with Early Breast Cancer

(2015) Liu Yang et al.   PLoS One

Differential regulation of genomic imprinting by TET proteins in embryonic stem cells

(2015) Lizhi Liu et al.   Stem Cell Research

Induced Pluripotency and Epigenetic Reprogramming

(2015) Konrad Hochedlinger et al.   Cold Spring Harbor Perspectives in Biology

DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis

(2015) Rajneesh Pathania et al.   Nature Communications

MiR137 is an androgen regulated repressor of an extended network of transcriptional coregulators

(2015) Emeli M. Nilsson et al.   Oncotarget

KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation

(2015) Changcun Guo et al.   Oncotarget

Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine.

(2015) Sevin Turcan et al.   Oncotarget

Tet and TDG Mediate DNA Demethylation Essential for Mesenchymal-to-Epithelial Transition in Somatic Cell Reprogramming

(2014) Xiao Hu et al.   Cell Stem Cell

Pioneer transcription factors in cell reprogramming

(2014) Makiko Iwafuchi-Doi et al.   GENES & DEVELOPMENT

TET proteins and 5-methylcytosine oxidation in hematological cancers

(2014) Myunggon Ko et al.   IMMUNOLOGICAL REVIEWS

The bone marrow niche for haematopoietic stem cells

(2014) Sean J. Morrison et al.   NATURE

Isocitrate dehydrogenase status and molecular subclasses of glioma and glioblastoma

(2014) Sameer Agnihotri et al.   Neurosurgical Focus

Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells

(2014) Y. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Brief Reports: A Distinct DNA Methylation Signature Defines Breast Cancer Stem Cells and Predicts Cancer Outcome

(2014) Rita El Helou et al.   STEM CELLS

5-Hydroxymethylcytosine Plays a Critical Role in Glioblastomagenesis by Recruiting the CHTOP-Methylosome Complex

(2014) Hiroki Takai et al.   Cell Reports

Distinct and overlapping control of 5-methylcytosine and 5-hydroxymethylcytosine by the TET proteins in human cancer cells

(2014) Emily L Putiri et al.   GENOME BIOLOGY

Clinical relevance of cancer stem cells in bone marrow of early breast cancer patients

(2013) A. Giordano et al.   ANNALS OF ONCOLOGY

Ten-eleven translocation (Tet) and thymine DNA glycosylase (TDG), components of the demethylation pathway, are direct targets of miRNA-29a

(2013) Pei Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Plasma S-adenosylmethionine, DNMTpolymorphisms, and peripheral blood LINE-1 methylation among healthy Chinese adults in Singapore

(2013) Maki Inoue-Choi et al.   BMC CANCER

Influence of Metabolism on Epigenetics and Disease

(2013) William G. Kaelin et al.   CELL

Dynamic Readers for 5-(Hydroxy)Methylcytosine and Its Oxidized Derivatives

(2013) Cornelia G. Spruijt et al.   CELL

Replacement of Oct4 by Tet1 during iPSC Induction Reveals an Important Role of DNA Methylation and Hydroxymethylation in Reprogramming

(2013) Yawei Gao et al.   Cell Stem Cell

PRDM14 promotes active DNA demethylation through the Ten-eleven translocation (TET)-mediated base excision repair pathway in embryonic stem cells

(2013) N. Okashita et al.   DEVELOPMENT

Dysregulation of the epigenome in triple-negative breast cancers: Basal-like and claudin-low breast cancers express aberrant DNA hypermethylation

(2013) J. Devon Roll et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

miR-329 suppresses the growth and motility of neuroblastoma by targeting KDM1A

(2013) Haifeng Yang et al.   FEBS LETTERS

Glioblastoma and Other Malignant Gliomas

(2013) Antonio Omuro   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Regulation of microRNAs by epigenetics and their interplay involved in cancer

(2013) Xiaolan Liu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

TET enzymes, TDG and the dynamics of DNA demethylation

(2013) Rahul M. Kohli et al.   NATURE

The nexus of chromatin regulation and intermediary metabolism

(2013) Philipp Gut et al.   NATURE

Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX

(2013) Myunggon Ko et al.   NATURE

Rare insights into cancer biology

(2013) J Adam et al.   ONCOGENE

Inactive DNMT3B Splice Variants Modulate De Novo DNA Methylation

(2013) Catherine A. Gordon et al.   PLoS One

MicroRNA-26a targets ten eleven translocation enzymes and is regulated during pancreatic cell differentiation

(2013) X. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic Reprogramming in Cancer

(2013) M. L. Suva et al.   SCIENCE

Epigenetic silencing of microRNA-203 is required for EMT and cancer stem cell properties

(2013) Joseph H. Taube et al.   Scientific Reports

An Extensive Network of TET2-Targeting MicroRNAs Regulates Malignant Hematopoiesis

(2013) Jijun Cheng et al.   Cell Reports

Delivery of Functional Anti-miR-9 by Mesenchymal Stem Cell–derived Exosomes to Glioblastoma Multiforme Cells Conferred Chemosensitivity

(2013) Jessian L Munoz et al.   Molecular Therapy-Nucleic Acids

Nuclear Exclusion of TET1 Is Associated with Loss of 5-Hydroxymethylcytosine in IDH1 Wild-Type Gliomas

(2012) Tim Müller et al.   AMERICAN JOURNAL OF PATHOLOGY

Exogenous CXCL12 activates protein kinase C to phosphorylate connexin 43 for gap junctional intercellular communication among confluent breast cancer cells

(2012) Jacqueline M. Park et al.   CANCER LETTERS

A review of methionine dependency and the role of methionine restriction in cancer growth control and life-span extension

(2012) Paul Cavuoto et al.   CANCER TREATMENT REVIEWS

Inhibition of  -KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors

(2012) M. Xiao et al.   GENES & DEVELOPMENT

IDH1 mutations inhibit multiple α-ketoglutarate-dependent dioxygenase activities in astroglioma

(2012) Ying Liu et al.   JOURNAL OF NEURO-ONCOLOGY

5-formylcytosine and 5-carboxylcytosine reduce the rate and substrate specificity of RNA polymerase II transcription

(2012) Matthew W Kellinger et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Epigenetic regulation of CD133/PROM1 expression in glioma stem cells by Sp1/myc and promoter methylation

(2012) G Gopisetty et al.   ONCOGENE

Exogenous expression of UHRF1 promotes proliferation and metastasis of breast cancer cells

(2012) Xin-Li Li   ONCOLOGY REPORTS

Disseminated Breast Cancer Cells Acquire a Highly Malignant and Aggressive Metastatic Phenotype during Metastatic Latency in the Bone

(2012) Carolyn G. Marsden et al.   PLoS One

Delineation of breast cancer cell hierarchy identifies the subset responsible for dormancy

(2012) Shyam A. Patel et al.   Scientific Reports

TET1 Suppresses Cancer Invasion by Activating the Tissue Inhibitors of Metalloproteinases

(2012) Chih-Hung Hsu et al.   Cell Reports

Pluripotency Factors in Embryonic Stem Cells Regulate Differentiation into Germ Layers

(2011) Matt Thomson et al.   CELL

Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids

(2011) Lakshminarayan M. Iyer et al.   CELL CYCLE

A Precarious Balance: Pluripotency Factors as Lineage Specifiers

(2011) Kyle M. Loh et al.   Cell Stem Cell

DNA Methylation of Tumor Suppressor and Metastasis Suppressor Genes in Circulating Tumor Cells

(2011) M. Chimonidou et al.   CLINICAL CHEMISTRY

Methylome analysis reveals Jak-STAT pathway deregulation in putative breast cancer stem cells

(2011) Héctor Hernández-Vargas et al.   Epigenetics

Genome-wide Regulation of 5hmC, 5mC, and Gene Expression by Tet1 Hydroxylase in Mouse Embryonic Stem Cells

(2011) Yufei Xu et al.   MOLECULAR CELL

Role of PTEN promoter methylation in tamoxifen-resistant breast cancer cells

(2010) Nguyen Thi Thuy Phuong et al.   BREAST CANCER RESEARCH AND TREATMENT

Breast cancer cell dormancy in bone marrow: potential therapeutic targets within the marrow microenvironment

(2010) Pranela Rameshwar   Expert Review of Anticancer Therapy

Differentiation of tubular and villous adenomas based on Wnt pathway-related gene expression profiles

(2010) Holcombe   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Tissue Distribution of 5-Hydroxymethylcytosine and Search for Active Demethylation Intermediates

(2010) Daniel Globisch et al.   PLoS One

DNA methylation and cellular reprogramming

(2010) Daniel D. De Carvalho et al.   TRENDS IN CELL BIOLOGY

Impact of the DNA methyltransferases expression on the methylation status of apoptosis-associated genes in glioblastoma multiforme

(2010) E Hervouet et al.   Cell Death & Disease

Drug discovery targeting epigenetic codes: The great potential of UHRF1, which links DNA methylation and histone modifications, as a drug target in cancers and toxoplasmosis

(2009) Motoko Unoki et al.   BIOCHEMICAL PHARMACOLOGY

Direct cell reprogramming is a stochastic process amenable to acceleration

(2009) Jacob Hanna et al.   NATURE

Immortalization eliminates a roadblock during cellular reprogramming into iPS cells

(2009) Jochen Utikal et al.   NATURE

Orphan nuclear receptor TLX activates Wnt/β-catenin signalling to stimulate neural stem cell proliferation and self-renewal

(2009) Qiuhao Qu et al.   NATURE CELL BIOLOGY

Cancer micrometastases

(2009) Klaus Pantel et al.   Nature Reviews Clinical Oncology

IDH1andIDH2Mutations in Gliomas

(2009) Hai Yan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Multiple Lineages of Human Breast Cancer Stem/Progenitor Cells Identified by Profiling with Stem Cell Markers

(2009) Wendy W. Hwang-Verslues et al.   PLoS One

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

The role of hypoxia-inducible factors in tumorigenesis

(2008) E B Rankin et al.   CELL DEATH AND DIFFERENTIATION

An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors

(2008) Ittai Ben-Porath et al.   NATURE GENETICS