标题
Drug Resistance Driven by Cancer Stem Cells and Their Niche
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 18, Issue 12, Pages 2574
出版商
MDPI AG
发表日期
2017-12-02
DOI
10.3390/ijms18122574
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Impact of Diabetes, Insulin, and Metformin Use on the Outcome of Patients With Human Epidermal Growth Factor Receptor 2–Positive Primary Breast Cancer: Analysis From the ALTTO Phase III Randomized Trial
- (2017) Amir Sonnenblick et al. JOURNAL OF CLINICAL ONCOLOGY
- Salinomycin kills cancer stem cells by sequestering iron in lysosomes
- (2017) Trang Thi Mai et al. Nature Chemistry
- EMT, CSCs, and drug resistance: the mechanistic link and clinical implications
- (2017) Tsukasa Shibue et al. Nature Reviews Clinical Oncology
- The self-renewal signaling pathways utilized by gastric cancer stem cells
- (2017) Ying Fu et al. TUMOR BIOLOGY
- Cisplatin-enriching cancer stem cells confer multidrug resistance in non-small cell lung cancer via enhancing TRIB1/HDAC activity
- (2017) Lihui Wang et al. Cell Death & Disease
- Targeting hypoxic cancer stem cells (CSCs) with Doxycycline: Implications for optimizing anti-angiogenic therapy
- (2017) Ernestina Marianna De Francesco et al. Oncotarget
- Stemness in Cancer: Stem Cells, Cancer Stem Cells, and Their Microenvironment
- (2017) Pedro M. Aponte et al. Stem Cells International
- All-trans retinoic acids induce differentiation and sensitize a radioresistant breast cancer cells to chemotherapy
- (2016) Yunwen Yan et al. BMC Complementary and Alternative Medicine
- Cancer statistics, 2016
- (2016) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- The cancer stem-cell signaling network and resistance to therapy
- (2016) A. Carnero et al. CANCER TREATMENT REVIEWS
- Implications of cancer stem cells in developing therapeutic resistance in oral cancer
- (2016) Prajna Paramita Naik et al. ORAL ONCOLOGY
- Therapeutic Implications of Cellular Heterogeneity and Plasticity in Breast Cancer
- (2015) Michael D. Brooks et al. Cell Stem Cell
- The Cancer Stem Cell Niche: How Essential Is the Niche in Regulating Stemness of Tumor Cells?
- (2015) Vicki Plaks et al. Cell Stem Cell
- Carbonic Anhydrase 9 mRNA/microRNA34a Interplay in Hypoxic Human Mammospheres
- (2015) Sabrina De Carolis et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells
- (2015) Devon A. Lawson et al. NATURE
- The cancer stem cell gamble
- (2015) J. Kaiser SCIENCE
- Twist1 and Snail Link Hedgehog Signaling to Tumor-Initiating Cell-Like Properties and Acquired Chemoresistance Independently of ABC Transporters
- (2015) Ying Kong et al. STEM CELLS
- Hedgehog pathway inhibitor in combination with radiation therapy for basal cell carcinomas of the head and neck
- (2015) Björn Schulze et al. STRAHLENTHERAPIE UND ONKOLOGIE
- Loss of microRNA-27b contributes to breast cancer stem cell generation by activating ENPP1
- (2015) Ryou-u Takahashi et al. Nature Communications
- Physical Intimacy of Breast Cancer Cells with Mesenchymal Stem Cells Elicits Trastuzumab Resistance through Src Activation
- (2015) Amita Daverey et al. Scientific Reports
- Lipid Raft-Mediated Regulation of Hyaluronan–CD44 Interactions in Inflammation and Cancer
- (2015) Toshiyuki Murai Frontiers in Immunology
- Hedgehog Signaling in the Maintenance of Cancer Stem Cells
- (2015) Catherine Cochrane et al. Cancers
- Fibroblast-Derived Exosomes Contribute to Chemoresistance through Priming Cancer Stem Cells in Colorectal Cancer
- (2015) Yibing Hu et al. PLoS One
- Simultaneous Inhibition of EGFR/VEGFR and Cyclooxygenase-2 Targets Stemness-Related Pathways in Colorectal Cancer Cells
- (2015) Araceli Valverde et al. PLoS One
- Metformin: Multi-faceted protection against cancer
- (2015) Sonia Del Barco et al. Oncotarget
- ALDH1A1 overexpression is associated with the progression and prognosis in gastric cancer
- (2014) Xiao-shan Li et al. BMC CANCER
- The PRKCI and SOX2 Oncogenes Are Coamplified and Cooperate to Activate Hedgehog Signaling in Lung Squamous Cell Carcinoma
- (2014) Verline Justilien et al. CANCER CELL
- Cancer stem-like cells from head and neck cancers are chemosensitized by the Wnt antagonist, sFRP4, by inducing apoptosis, decreasing stemness, drug resistance and epithelial to mesenchymal transition
- (2014) S Warrier et al. CANCER GENE THERAPY
- Distinct Subpopulations of Head and Neck Cancer Cells with Different Levels of Intracellular Reactive Oxygen Species Exhibit Diverse Stemness, Proliferation, and Chemosensitivity
- (2014) C.-W. Chang et al. CANCER RESEARCH
- Endothelial Cell-Secreted EGF Induces Epithelial to Mesenchymal Transition and Endows Head and Neck Cancer Cells with Stem-like Phenotype
- (2014) Z. Zhang et al. CANCER RESEARCH
- The Cancer Stem Cell Marker Aldehyde Dehydrogenase Is Required to Maintain a Drug-Tolerant Tumor Cell Subpopulation
- (2014) D. Raha et al. CANCER RESEARCH
- Exosome Transfer from Stromal to Breast Cancer Cells Regulates Therapy Resistance Pathways
- (2014) Mirjam C. Boelens et al. CELL
- PPARγ and RXR Ligands Disrupt the Inflammatory Cross-talk in the Hypoxic Breast Cancer Stem Cells Niche
- (2014) Alessio Papi et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Interaction between gastric cancer stem cells and the tumor microenvironment
- (2014) Takatsugu Ishimoto et al. JOURNAL OF GASTROENTEROLOGY
- Overexpression of NRG1 promotes progression of gastric cancer by regulating the self-renewal of cancer stem cells
- (2014) Myoung-Eun Han et al. JOURNAL OF GASTROENTEROLOGY
- A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages
- (2014) Haihui Lu et al. NATURE CELL BIOLOGY
- Evaluation of Cancer Stem Cell Markers CD133, CD44, CD24: Association with AKT Isoforms and Radiation Resistance in Colon Cancer Cells
- (2014) Sara Häggblad Sahlberg et al. PLoS One
- Identification of an ABCB1 (P-glycoprotein)-positive carfilzomib-resistant myeloma subpopulation by the pluripotent stem cell fluorescent dye CDy1
- (2013) Teresa S. Hawley et al. AMERICAN JOURNAL OF HEMATOLOGY
- Matricellular proteins: priming the tumour microenvironment for cancer development and metastasis
- (2013) G S Wong et al. BRITISH JOURNAL OF CANCER
- Cancer-associated fibroblasts induce epithelial–mesenchymal transition of breast cancer cells through paracrine TGF-β signalling
- (2013) Y Yu et al. BRITISH JOURNAL OF CANCER
- Endothelial Cells Promote the Colorectal Cancer Stem Cell Phenotype through a Soluble Form of Jagged-1
- (2013) Jia Lu et al. CANCER CELL
- FOXC2 Expression Links Epithelial-Mesenchymal Transition and Stem Cell Properties in Breast Cancer
- (2013) B. G. Hollier et al. CANCER RESEARCH
- MicroRNA-Antagonism Regulates Breast Cancer Stemness and Metastasis via TET-Family-Dependent Chromatin Remodeling
- (2013) Su Jung Song et al. CELL
- The Oncogenic MicroRNA miR-22 Targets the TET2 Tumor Suppressor to Promote Hematopoietic Stem Cell Self-Renewal and Transformation
- (2013) Su Jung Song et al. Cell Stem Cell
- Triptolide reverses hypoxia-induced epithelial-mesenchymal transition and stem-like features in pancreatic cancer by NF-κB downregulation
- (2013) Li Liu et al. INTERNATIONAL JOURNAL OF CANCER
- Single-cell clones of liver cancer stem cells have the potential of differentiating into different types of tumor cells
- (2013) H Liu et al. Cell Death & Disease
- Intratumoral macrophages contribute to epithelial-mesenchymal transition in solid tumors
- (2012) Anne-Katrine Bonde et al. BMC CANCER
- Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma
- (2012) Paolo P. Provenzano et al. CANCER CELL
- Cancer Stem Cells: Impact, Heterogeneity, and Uncertainty
- (2012) Jeffrey A. Magee et al. CANCER CELL
- CCL2 Mediates Cross-talk between Cancer Cells and Stromal Fibroblasts That Regulates Breast Cancer Stem Cells
- (2012) A. Tsuyada et al. CANCER RESEARCH
- A CXCL1 Paracrine Network Links Cancer Chemoresistance and Metastasis
- (2012) Swarnali Acharyya et al. CELL
- Understanding cancer stem cell heterogeneity and plasticity
- (2012) Dean G Tang CELL RESEARCH
- Ionizing radiation induces mitochondrial reactive oxygen species production accompanied by upregulation of mitochondrial electron transport chain function and mitochondrial content under control of the cell cycle checkpoint
- (2012) Tohru Yamamori et al. FREE RADICAL BIOLOGY AND MEDICINE
- Enhanced cisplatin resistance in oral-cancer stem-like cells is correlated with upregulation of excision-repair cross-complementation group 1
- (2012) Lo-Lin Tsai et al. Journal of Dental Sciences
- Snail overexpression induces an epithelial to mesenchymal transition and cancer stem cell-like properties in SCC9 cells
- (2012) Li-Fang Zhu et al. LABORATORY INVESTIGATION
- Reactive oxygen species and aldehyde dehydrogenase activity in Hodgkin lymphoma cells
- (2012) Jun-ichiro Ikeda et al. LABORATORY INVESTIGATION
- Activation of an IL6 Inflammatory Loop Mediates Trastuzumab Resistance in HER2+ Breast Cancer by Expanding the Cancer Stem Cell Population
- (2012) Hasan Korkaya et al. MOLECULAR CELL
- Epigenetic alterations involved in cancer stem cell reprogramming
- (2012) Purificación Muñoz et al. Molecular Oncology
- Defining the mode of tumour growth by clonal analysis
- (2012) Gregory Driessens et al. NATURE
- Efficacy and Safety of Vismodegib in Advanced Basal-Cell Carcinoma
- (2012) Aleksandar Sekulic et al. NEW ENGLAND JOURNAL OF MEDICINE
- Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing
- (2012) Marco Gerlinger et al. NEW ENGLAND JOURNAL OF MEDICINE
- Acute WNT signalling activation perturbs differentiation within the adult stomach and rapidly leads to tumour formation
- (2012) S Radulescu et al. ONCOGENE
- A CD44high/EGFRlow Subpopulation within Head and Neck Cancer Cell Lines Shows an Epithelial-Mesenchymal Transition Phenotype and Resistance to Treatment
- (2012) Linnea La Fleur et al. PLoS One
- Hypoxia-Induced Aggressiveness of Pancreatic Cancer Cells Is Due to Increased Expression of VEGF, IL-6 and miR-21, Which Can Be Attenuated by CDF Treatment
- (2012) Bin Bao et al. PLoS One
- Recurrent Oral Cancer: Current and Emerging Therapeutic Approaches
- (2012) Sabrina Daniela da Silva et al. Frontiers in Pharmacology
- Drug Transporters in Drug Efficacy and Toxicity
- (2011) M.K. DeGorter et al. Annual Review of Pharmacology and Toxicology
- Anti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells
- (2011) Ubaldo E. Martinez-Outschoorn et al. CANCER BIOLOGY & THERAPY
- Breast Cancer Stem Cells Are Regulated by Mesenchymal Stem Cells through Cytokine Networks
- (2011) Suling Liu et al. CANCER RESEARCH
- Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells
- (2011) Piyush B. Gupta et al. CELL
- Paracrine and Autocrine Signals Induce and Maintain Mesenchymal and Stem Cell States in the Breast
- (2011) Christina Scheel et al. CELL
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial–mesenchymal transition
- (2011) Nam Hee Kim et al. JOURNAL OF CELL BIOLOGY
- An integrative genomic analysis revealed the relevance of microRNA and gene expression for drug-resistance in human breast cancer cells
- (2011) Yusuke Yamamoto et al. Molecular Cancer
- CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
- (2011) Bin-Zhi Qian et al. NATURE
- Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs
- (2011) Thordur Oskarsson et al. NATURE MEDICINE
- Epithelial and Mesenchymal Subpopulations Within Normal Basal Breast Cell Lines Exhibit Distinct Stem Cell/Progenitor Properties
- (2011) David Sarrio et al. STEM CELLS
- Significance of Lgr5+ve Cancer Stem Cells in the Colon and Rectum
- (2010) Hidekazu Takahashi et al. ANNALS OF SURGICAL ONCOLOGY
- Endothelial cell transdifferentiation of human glioma stem progenitor cells in vitro
- (2010) Yaodong Zhao et al. BRAIN RESEARCH BULLETIN
- Molecular mechanisms underlying tumor dormancy
- (2010) Nava Almog CANCER LETTERS
- Endothelial Cell-Initiated Signaling Promotes the Survival and Self-Renewal of Cancer Stem Cells
- (2010) S. Krishnamurthy et al. CANCER RESEARCH
- Reciprocal Activation of Prostate Cancer Cells and Cancer-Associated Fibroblasts Stimulates Epithelial-Mesenchymal Transition and Cancer Stemness
- (2010) E. Giannoni et al. CANCER RESEARCH
- A Temporarily Distinct Subpopulation of Slow-Cycling Melanoma Cells Is Required for Continuous Tumor Growth
- (2010) Alexander Roesch et al. CELL
- Perivascular Nitric Oxide Activates Notch Signaling and Promotes Stem-like Character in PDGF-Induced Glioma Cells
- (2010) Nikki Charles et al. Cell Stem Cell
- The therapeutic promise of the cancer stem cell concept
- (2010) Natasha Y. Frank et al. JOURNAL OF CLINICAL INVESTIGATION
- Hypoxia-Inducible Factors and the Response to Hypoxic Stress
- (2010) Amar J. Majmundar et al. MOLECULAR CELL
- Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells
- (2010) Lucia Ricci-Vitiani et al. NATURE
- Glioblastoma stem-like cells give rise to tumour endothelium
- (2010) Rong Wang et al. NATURE
- Conversion of vascular endothelial cells into multipotent stem-like cells
- (2010) Damian Medici et al. NATURE MEDICINE
- How I treat acute promyelocytic leukemia
- (2009) M. S. Tallman et al. BLOOD
- Chemoresistant Colorectal Cancer Cells, the Cancer Stem Cell Phenotype, and Increased Sensitivity to Insulin-like Growth Factor-I Receptor Inhibition
- (2009) N. A. Dallas et al. CANCER RESEARCH
- Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission
- (2009) H. A. Hirsch et al. CANCER RESEARCH
- Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening
- (2009) Piyush B. Gupta et al. CELL
- Characterization and functional analysis of a slow cycling stem cell-like subpopulation in pancreas adenocarcinoma
- (2009) Jennifer L. Dembinski et al. CLINICAL & EXPERIMENTAL METASTASIS
- Cancer-associated fibroblasts and tumor growth – bystanders turning into key players
- (2009) Arne Östman et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Association of reactive oxygen species levels and radioresistance in cancer stem cells
- (2009) Maximilian Diehn et al. NATURE
- MicroRNA miR-34 Inhibits Human Pancreatic Cancer Tumor-Initiating Cells
- (2009) Qing Ji et al. PLoS One
- Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment
- (2009) G. Bertolini et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Breast cancer chemoresistance: Emerging importance of cancer stem cells
- (2009) Suebwong Chuthapisith et al. SURGICAL ONCOLOGY-OXFORD
- CD44+CD24− prostate cells are early cancer progenitor/stem cells that provide a model for patients with poor prognosis
- (2008) E M Hurt et al. BRITISH JOURNAL OF CANCER
- The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
- (2008) Sendurai A. Mani et al. CELL
- Prediction of Broad Spectrum Resistance of Tumors towards Anticancer Drugs
- (2008) T. Efferth et al. CLINICAL CANCER RESEARCH
- Endothelial cell differentiation of human breast tumour stem/progenitor cells
- (2008) Benedetta Bussolati et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- The role of oxygen availability in embryonic development and stem cell function
- (2008) M. Celeste Simon et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Oncologic Trogocytosis of an Original Stromal Cells Induces Chemoresistance of Ovarian Tumours
- (2008) Arash Rafii et al. PLoS One
- Hypoxia Enhances Tumor Stemness by Increasing the Invasive and Tumorigenic Side Population Fraction
- (2008) Bikul Das et al. STEM CELLS
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