High throughput chromatography strategies for potential use in the formal process characterization of a monoclonal antibody

A practical strategy for using miniature chromatography columns in a standardized high-throughput workflow for purification development of monoclonal antibodies

(2014) John P. Welsh et al.   BIOTECHNOLOGY PROGRESS

Adaptation of the pore diffusion model to describe multi-addition batch uptake high-throughput screening experiments

(2014) Steven J. Traylor et al.   JOURNAL OF CHROMATOGRAPHY A

Chromatography process development in the quality by design paradigm I: Establishing a high-throughput process development platform as a tool for estimating “characterization space” for an ion exchange chromatography step

(2013) R. Bhambure et al.   BIOTECHNOLOGY PROGRESS

High-throughput process development of chromatography steps: Advantages and limitations of different formats used

(2012) Karol M. Łącki   Biotechnology Journal

Predicting protein dynamic binding capacity from batch adsorption tests

(2012) Giorgio Carta   Biotechnology Journal

Strategic Assay Selection for analytics in high-throughput process development: Case studies for downstream processing of monoclonal antibodies

(2012) Spyridon Konstantinidis et al.   Biotechnology Journal

High-throughput methods for miniaturization and automation of monoclonal antibody purification processes

(2012) Katrin Treier et al.   BIOTECHNOLOGY PROGRESS

State-of-the-art in downstream processing of monoclonal antibodies: Process trends in design and validation

(2012) P. A. Marichal-Gallardo et al.   BIOTECHNOLOGY PROGRESS

Model-integrated process development demonstrated on the optimization of a robotic cation exchange step

(2012) A. Osberghaus et al.   CHEMICAL ENGINEERING SCIENCE

Therapeutic antibodies: Market considerations, disease targets and bioprocessing

(2011) John G. Elvin et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Designing new monoclonal antibody purification processes using mixed-mode chromatography sorbents

(2011) Magali Toueille et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

High-throughput process development for biopharmaceutical drug substances

(2011) Rahul Bhambure et al.   TRENDS IN BIOTECHNOLOGY

A review of advanced small-scale parallel bioreactor technology for accelerated process development: Current state and future need

(2010) Rachel Bareither et al.   BIOTECHNOLOGY PROGRESS

Review: Microscale methods for high-throughput chromatography development in the pharmaceutical industry

(2009) Sunil Chhatre et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

High-throughput screening of chromatographic separations: IV. Ion-exchange

(2008) Brian D. Kelley et al.   BIOTECHNOLOGY AND BIOENGINEERING

High-throughput screening of chromatographic separations: I. Method development and column modeling

(2008) Jonathan L. Coffman et al.   BIOTECHNOLOGY AND BIOENGINEERING

Weak partitioning chromatography for anion exchange purification of monoclonal antibodies

(2008) Brian D. Kelley et al.   BIOTECHNOLOGY AND BIOENGINEERING

Development and application of an automated, low-volume chromatography system for resin and condition screening

(2008) Mark Teeters et al.   Biotechnology Journal

High-Throughput Process Development: Determination of Dynamic Binding Capacity Using Microtiter Filter Plates Filled with Chromatography Resin

(2008) T. Bergander et al.   BIOTECHNOLOGY PROGRESS

High Throughput Screening for the Design and Optimization of Chromatographic Processes – Miniaturization, Automation and Parallelization of Breakthrough and Elution Studies

(2008) M. Wiendahl et al.   CHEMICAL ENGINEERING & TECHNOLOGY

High Throughput Screening for the Design and Optimization of Chromatographic Processes: Assessment of Model Parameter Determination from High Throughput Compatible Data

(2008) A. Susanto et al.   CHEMICAL ENGINEERING & TECHNOLOGY