标题
Emerging Insights into the Metabolic Alterations in Aging Using Metabolomics
作者
关键词
-
出版物
Metabolites
Volume 9, Issue 12, Pages 301
出版商
MDPI AG
发表日期
2019-12-14
DOI
10.3390/metabo9120301
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Alpha-ketoglutarate extends Drosophila lifespan by inhibiting mTOR and activating AMPK
- (2019) Yuan Su et al. Aging-US
- NMR Spectroscopy for Metabolomics Research
- (2019) Abdul-Hamid Emwas et al. Metabolites
- Methionine metabolism and methyltransferases in the regulation of aging and lifespan extension across species
- (2019) Andrey A. Parkhitko et al. AGING CELL
- Metabolomics-Based Studies Assessing Exercise-Induced Alterations of the Human Metabolome: A Systematic Review
- (2019) Camila Sakaguchi et al. Metabolites
- Comparative metabolomics of aging in a long-lived bat: Insights into the physiology of extreme longevity
- (2018) Hope C. Ball et al. PLoS One
- Non-enzymatic molecular damage as a prototypic driver of aging
- (2017) Alexey Golubev et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The gut microbiota of centenarians: Signatures of longevity in the gut microbiota profile
- (2017) Elena Biagi et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Metabolomics of mitochondrial disease
- (2017) Karien Esterhuizen et al. MITOCHONDRION
- HMDB 4.0: the human metabolome database for 2018
- (2017) David S Wishart et al. NUCLEIC ACIDS RESEARCH
- Aging increases cell-to-cell transcriptional variability upon immune stimulation
- (2017) Celia Pilar Martinez-Jimenez et al. SCIENCE
- Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease
- (2017) Min Wei et al. Science Translational Medicine
- The Mitochondrial Basis of Aging and Age-Related Disorders
- (2017) Sarika Srivastava Genes
- Metabolite patterns predicting sex and age in participants of the Karlsruhe Metabolomics and Nutrition (KarMeN) study
- (2017) Manuela J. Rist et al. PLoS One
- Mitochondrial metabolites extend lifespan
- (2016) Robert J. Mishur et al. AGING CELL
- Metabolic drift in the aging brain
- (2016) Julijana Ivanisevic et al. Aging-US
- DNA methylation-based measures of biological age: meta-analysis predicting time to death
- (2016) Brian H. Chen et al. Aging-US
- Recent Advances in NMR-Based Metabolomics
- (2016) G. A. Nagana Gowda et al. ANALYTICAL CHEMISTRY
- Exercise Promotes Healthy Aging of Skeletal Muscle
- (2016) Gregory D. Cartee et al. Cell Metabolism
- Gut Microbiota and Extreme Longevity
- (2016) Elena Biagi et al. CURRENT BIOLOGY
- Tissue-specific down-regulation of S-adenosyl-homocysteine via suppression of dAhcyL1/dAhcyL2 extends health span and life span inDrosophila
- (2016) Andrey A. Parkhitko et al. GENES & DEVELOPMENT
- Advantages and Pitfalls of Mass Spectrometry Based Metabolome Profiling in Systems Biology
- (2016) Ina Aretz et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Untargeted Metabolomics Strategies—Challenges and Emerging Directions
- (2016) Alexandra C. Schrimpe-Rutledge et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- The metabolome 18 years on: a concept comes of age
- (2016) Douglas B. Kell et al. Metabolomics
- Emerging applications of metabolomics in drug discovery and precision medicine
- (2016) David S. Wishart NATURE REVIEWS DRUG DISCOVERY
- Metabolomics of aging requires large-scale longitudinal studies with replication
- (2016) Ville-Petteri Mäkinen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Individual variability in human blood metabolites identifies age-related differences
- (2016) Romanas Chaleckis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Non-targeted and targeted metabolomics approaches to diagnosing lung cancer and predicting patient prognosis
- (2016) Xiaoli Zhang et al. Oncotarget
- Integration of ‘omics’ data in aging research: from biomarkers to systems biology
- (2015) Jonas Zierer et al. AGING CELL
- The effects of age and dietary restriction on the tissue-specific metabolome ofDrosophila
- (2015) Matthew J. Laye et al. AGING CELL
- Toward Merging Untargeted and Targeted Methods in Mass Spectrometry-Based Metabolomics and Lipidomics
- (2015) Tomas Cajka et al. ANALYTICAL CHEMISTRY
- A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan
- (2015) Sebastian Brandhorst et al. Cell Metabolism
- Organization of the Mammalian Metabolome according to Organ Function, Lineage Specialization, and Longevity
- (2015) Siming Ma et al. Cell Metabolism
- The Role of Metabolomics in Brain Metabolism Research
- (2015) Julijana Ivanisevic et al. Journal of Neuroimmune Pharmacology
- Measuring Biological Age via Metabonomics: The Metabolic Age Score
- (2015) Johannes Hertel et al. JOURNAL OF PROTEOME RESEARCH
- Human Aging Is a Metabolome-related Matter of Gender
- (2015) Mariona Jové et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- MARK-AGE biomarkers of ageing
- (2015) Alexander Bürkle et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Pharmacometabonomics in humans: a new tool for personalized medicine
- (2015) Jeremy R Everett PHARMACOGENOMICS
- Quantification of biological aging in young adults
- (2015) Daniel W. Belsky et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Proteomic analysis and functional characterization of mouse brain mitochondria during aging reveal alterations in energy metabolism
- (2015) Kelly L. Stauch et al. PROTEOMICS
- Transcription errors induce proteotoxic stress and shorten cellular lifespan
- (2015) Marc Vermulst et al. Nature Communications
- Distinct metabolomic signatures are associated with longevity in humans
- (2015) Susan Cheng et al. Nature Communications
- Protein biogenesis machinery is a driver of replicative aging in yeast
- (2015) Georges E Janssens et al. eLife
- Integrated Transcriptome and Proteome Analyses Reveal Organ-Specific Proteome Deterioration in Old Rats
- (2015) Alessandro Ori et al. Cell Systems
- Effects of age, sex, and genotype on high-sensitivity metabolomic profiles in the fruit fly,Drosophila melanogaster
- (2014) Jessica M. Hoffman et al. AGING CELL
- Metabolomics of Human Brain Aging and Age-Related Neurodegenerative Diseases
- (2014) Mariona Jové et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR
- (2014) Randall M. Chin et al. NATURE
- A metabolic view on menopause and ageing
- (2014) Kirsi Auro et al. Nature Communications
- Age- and diet-associated metabolome remodeling characterizes the aging process driven by damage accumulation
- (2014) Andrei S Avanesov et al. eLife
- Lipidomics of familial longevity
- (2013) Vanessa Gonzalez-Covarrubias et al. AGING CELL
- Genome Instability and Aging
- (2013) Jan Vijg et al. Annual Review of Physiology
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- Measuring the exposome: A powerful basis for evaluating environmental exposures and cancer risk
- (2013) Christopher P. Wild et al. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
- Metabolomic markers reveal novel pathways of ageing and early development in human populations
- (2013) Cristina Menni et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Microbial–Mammalian Cometabolites Dominate the Age-associated Urinary Metabolic Phenotype in Taiwanese and American Populations
- (2013) Jonathan R. Swann et al. JOURNAL OF PROTEOME RESEARCH
- Liquid chromatography quadrupole time-of-flight mass spectrometry characterization of metabolites guided by the METLIN database
- (2013) Zheng-Jiang Zhu et al. Nature Protocols
- Omics technologies and the study of human ageing
- (2013) Ana M. Valdes et al. NATURE REVIEWS GENETICS
- Correction: Metabolic Signatures of Extreme Longevity in Northern Italian Centenarians Reveal a Complex Remodeling of Lipids, Amino Acids, and Gut Microbiota Metabolism
- (2013) Sebastiano Collino et al. PLoS One
- The Human Urine Metabolome
- (2013) Souhaila Bouatra et al. PLoS One
- Gene expression changes with age in skin, adipose tissue, blood and brain
- (2013) Daniel Glass et al. GENOME BIOLOGY
- Chronic caloric restriction partially protects against age-related alteration in serum metabolome
- (2012) Jennifer M. De Guzman et al. AGE
- A metabolic signature predicts biological age in mice
- (2012) Antonia Tomás-Loba et al. AGING CELL
- Human serum metabolic profiles are age dependent
- (2012) Zhonghao Yu et al. AGING CELL
- Nutritional Metabolomics: Progress in Addressing Complexity in Diet and Health
- (2012) Dean P. Jones et al. Annual Review of Nutrition
- Metabotyping of Long-Lived Mice using 1H NMR Spectroscopy
- (2012) Anisha Wijeyesekera et al. JOURNAL OF PROTEOME RESEARCH
- Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates
- (2012) Gregory Hannum et al. MOLECULAR CELL
- Global metabolic profiling of animal and human tissues via UPLC-MS
- (2012) Elizabeth J Want et al. Nature Protocols
- Metabolomics: the apogee of the omics trilogy
- (2012) Gary J. Patti et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Insights into CNS ageing from animal models of senescence
- (2012) Mark Yeoman et al. NATURE REVIEWS NEUROSCIENCE
- Aging effects on DNA methylation modules in human brain and blood tissue
- (2012) Steve Horvath et al. GENOME BIOLOGY
- Modern analytical techniques in metabolomics analysis
- (2011) Aihua Zhang et al. ANALYST
- Mass spectrometry-based holistic analytical approaches for metabolite profiling in systems biology studies
- (2011) Georgios Theodoridis et al. MASS SPECTROMETRY REVIEWS
- Metabolomics: from small molecules to big ideas
- (2011) Monya Baker NATURE METHODS
- Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry
- (2011) Warwick B Dunn et al. Nature Protocols
- YMDB: the Yeast Metabolome Database
- (2011) T. Jewison et al. NUCLEIC ACIDS RESEARCH
- MMMDB: Mouse Multiple Tissue Metabolome Database
- (2011) Masahiro Sugimoto et al. NUCLEIC ACIDS RESEARCH
- The Human Serum Metabolome
- (2011) Nikolaos Psychogios et al. PLoS One
- The metabolic footprint of aging in mice
- (2011) Riekelt H. Houtkooper et al. Scientific Reports
- Lipid metabolism in long-lived families: the Leiden Longevity Study
- (2010) Anika A. M. Vaarhorst et al. AGE
- High-Throughput and Multiplexed LC/MS/MRM Method for Targeted Metabolomics
- (2010) Ru Wei et al. ANALYTICAL CHEMISTRY
- A metabolic signature of long life in Caenorhabditis elegans
- (2010) Silke Fuchs et al. BMC BIOLOGY
- Systems Biology and Longevity: An Emerging Approach to Identify Innovative Anti- Aging Targets and Strategies
- (2010) E. Cevenini et al. CURRENT PHARMACEUTICAL DESIGN
- MassBank: a public repository for sharing mass spectral data for life sciences
- (2010) Hisayuki Horai et al. JOURNAL OF MASS SPECTROMETRY
- Inborn variation in metabolism
- (2010) Vamsi K Mootha et al. NATURE GENETICS
- What are biomarkers?
- (2010) Kyle Strimbu et al. Current Opinion in HIV and AIDS
- Metabolomics: Unraveling the chemical individuality of common human diseases
- (2009) Sander M. Houten ANNALS OF MEDICINE
- Metabolomics for Functional Genomics, Systems Biology, and Biotechnology
- (2009) Kazuki Saito et al. Annual Review of Plant Biology
- A genome-wide perspective of genetic variation in human metabolism
- (2009) Thomas Illig et al. NATURE GENETICS
- Metabolomics: A Global Biochemical Approach to Drug Response and Disease
- (2008) Rima Kaddurah-Daouk et al. Annual Review of Pharmacology and Toxicology
- Metabolomics
- (2008) V. Gomase et al. CURRENT DRUG METABOLISM
- Metabolite identification via the Madison Metabolomics Consortium Database
- (2008) Qiu Cui et al. NATURE BIOTECHNOLOGY
- Metabolomics: A Global Biochemical Approach to the Study of Central Nervous System Diseases
- (2008) Rima Kaddurah-Daouk et al. NEUROPSYCHOPHARMACOLOGY
- Analysis of the adult human plasma metabolome
- (2008) Kay A Lawton et al. PHARMACOGENOMICS
- Applications of Metabolomics in Drug Discovery and Development
- (2008) David S Wishart Drugs in research & development
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started