Emergence of Novel Coronavirus 2019-nCoV: Need for Rapid Vaccine and Biologics Development

Receptor recognition by novel coronavirus from Wuhan: An analysis based on decade-long structural studies of SARS

(2020) Yushun Wan et al.   JOURNAL OF VIROLOGY

Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding

(2020) Roujian Lu et al.   LANCET

A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster

(2020) Jasper Fuk-Woo Chan et al.   LANCET

Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study

(2020) Nanshan Chen et al.   LANCET

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

A Novel Coronavirus from Patients with Pneumonia in China, 2019

(2020) Na Zhu et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Broad and Potent H1-Specific Human Monoclonal Antibody Produced in Plants Prevents Influenza Virus Infection and Transmission in Guinea Pigs

(2020) Jun-Gyu Park et al.   Viruses-Basel

From SARS to MERS, Thrusting Coronaviruses into the Spotlight

(2019) Zhiqi Song et al.   Viruses-Basel

In vitro and in vivo efficacy of anti-chikungunya virus monoclonal antibodies produced in wild-type and glycoengineered Nicotiana benthamiana plants

(2019) Jonathan Hurtado et al.   PLANT BIOTECHNOLOGY JOURNAL

Recent Advances in the Vaccine Development Against Middle East Respiratory Syndrome-Coronavirus

(2019) Chean Yeah Yong et al.   Frontiers in Microbiology

Production and Immunogenicity of Soluble Plant-Produced HIV-1 Subtype C Envelope gp140 Immunogens

(2019) Emmanuel Margolin et al.   Frontiers in Plant Science

Plant-Produced Anti-Enterovirus 71 (EV71) Monoclonal Antibody Efficiently Protects Mice Against EV71 Infection

(2019) Kaewta Rattanapisit et al.   Plants-Basel

Molecular Pharming for low and middle income countries

(2019) Sheeba Murad et al.   CURRENT OPINION IN BIOTECHNOLOGY

Development of Systems for the Production of Plant-Derived Biopharmaceuticals

(2019) Ki-Beom Moon et al.   Plants-Basel

Origin and evolution of pathogenic coronaviruses

(2018) Jie Cui et al.   NATURE REVIEWS MICROBIOLOGY

Cold chain and virus-free oral polio booster vaccine made in lettuce chloroplasts confers protection against all three poliovirus serotypes

(2018) Henry Daniell et al.   PLANT BIOTECHNOLOGY JOURNAL

Enhanced transport of plant-produced rabies single-chain antibody-RVG peptide fusion protein across an in cellulo blood-brain barrier device

(2017) Waranyoo Phoolcharoen et al.   PLANT BIOTECHNOLOGY JOURNAL

Rapid Transient Production of a Monoclonal Antibody Neutralizing the Porcine Epidemic Diarrhea Virus (PEDV) in Nicotiana benthamiana and Lactuca sativa

(2017) Kaewta Rattanapisit et al.   PLANTA MEDICA

Plant-made polio type 3 stabilized VLPs—a candidate synthetic polio vaccine

(2017) Johanna Marsian et al.   Nature Communications

A Perspective on the Development of Plant-Made Vaccines in the Fight against Ebola Virus

(2017) Sergio Rosales-Mendoza et al.   Frontiers in Immunology

Plant-produced anti-dengue virus monoclonal antibodies exhibit reduced antibody-dependent enhancement of infection activity

(2016) Matthew Dent et al.   JOURNAL OF GENERAL VIROLOGY

Cold chain and virus-free chloroplast-made booster vaccine to confer immunity against different poliovirus serotypes

(2016) Hui-Ting Chan et al.   PLANT BIOTECHNOLOGY JOURNAL

Structure, Function, and Evolution of Coronavirus Spike Proteins

(2016) Fang Li   Annual Review of Virology

Plant-made pharmaceuticals: from ‘Edible Vaccines’ to Ebola therapeutics

(2015) Charles Arntzen   PLANT BIOTECHNOLOGY JOURNAL

Plant-made oral vaccines against human infectious diseases-Are we there yet?

(2015) Hui-Ting Chan et al.   PLANT BIOTECHNOLOGY JOURNAL

Commercialization of new biotechnology: a systematic review of 16 commercial case studies in a novel manufacturing sector

(2015) Matthew J. Paul et al.   PLANT BIOTECHNOLOGY JOURNAL

Regulatory approval and a first-in-human phase I clinical trial of a monoclonal antibody produced in transgenic tobacco plants

(2015) Julian K-C. Ma et al.   PLANT BIOTECHNOLOGY JOURNAL

Plant-produced candidate countermeasures against emerging and reemerging infections and bioterror agents

(2015) Stephen J. Streatfield et al.   PLANT BIOTECHNOLOGY JOURNAL

Expression of H3N2 nucleoprotein in maize seeds and immunogenicity in mice

(2015) Hartinio N. Nahampun et al.   PLANT CELL REPORTS

Engineering, Expression in Transgenic Plants and Characterisation of E559, a Rabies Virus-Neutralising Monoclonal Antibody

(2014) Craig J. van Dolleweerd et al.   JOURNAL OF INFECTIOUS DISEASES

Expression of Rabies Glycoprotein and Ricin Toxin B Chain (RGP–RTB) Fusion Protein in Tomato Hairy Roots: A Step Towards Oral Vaccination for Rabies

(2014) Ankit Singh et al.   MOLECULAR BIOTECHNOLOGY

Taliglucerase alfa: An enzyme replacement therapy using plant cell expression technology

(2014) Gregory A. Grabowski et al.   MOLECULAR GENETICS AND METABOLISM

Structural and functional characterization of an anti-West Nile virus monoclonal antibody and its single-chain variant produced in glycoengineered plants

(2014) Huafang Lai et al.   PLANT BIOTECHNOLOGY JOURNAL

Oral delivery of plant-derived HIV-1 p24 antigen in low doses shows a superior priming effect in mice compared to high doses

(2014) Ingrid Lindh et al.   VACCINE

Supercritical fluid extraction provides an enhancement to the immune response for orally-delivered hepatitis B surface antigen

(2014) Celine A. Hayden et al.   VACCINE

Plant-based vaccines against viruses

(2014) Edward P Rybicki   Virology Journal

Freeze-Drying of Plant Tissue Containing HBV Surface Antigen for the Oral Vaccine against Hepatitis B

(2014) Marcin Czyż et al.   Biomed Research International

Immunization with an HPV-16 L1-based chimeric virus-like particle containing HPV-16 E6 and E7 epitopes elicits long-lasting prophylactic and therapeutic efficacy in an HPV-16 tumor mice model

(2013) Alberto Monroy-García et al.   ARCHIVES OF VIROLOGY

Production, characterization, and antigen specificity of recombinant 62-71-3, a candidate monoclonal antibody for rabies prophylaxis in humans

(2013) Leonard Both et al.   FASEB JOURNAL

Characterization of VRC01, a potent and broadly neutralizing anti-HIV mAb, produced in transiently and stably transformed tobacco

(2013) Audrey Y-H. Teh et al.   PLANT BIOTECHNOLOGY JOURNAL

Immunogenic properties of a lettuce-derived C4(V3)6 multiepitopic HIV protein

(2013) Dania O. Govea-Alonso et al.   PLANTA

A chloroplast-derived C4V3 polypeptide from the human immunodeficiency virus (HIV) is orally immunogenic in mice

(2012) Néstor Rubio-Infante et al.   PLANT MOLECULAR BIOLOGY

Induction of a protective immune response to rabies virus in sheep after oral immunization with transgenic maize, expressing the rabies virus glycoprotein

(2012) Elizabeth Loza-Rubio et al.   VACCINE

Transgenic tobacco expressed HPV16-L1 and LT-B combined immunization induces strong mucosal and systemic immune responses in mice

(2012) Liu Hongli et al.   Human Vaccines & Immunotherapeutics

Plant-made pharmaceuticals: Leading products and production platforms

(2011) Matthew Paul et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Immunogenicity of chloroplast-derived HIV-1 p24 and a p24-Nef fusion protein following subcutaneous and oral administration in mice

(2011) Nuria Gonzalez-Rabade et al.   PLANT BIOTECHNOLOGY JOURNAL

Expression of an immunogenic Ebola immune complex in Nicotiana benthamiana

(2011) Waranyoo Phoolcharoen et al.   PLANT BIOTECHNOLOGY JOURNAL

Neutralizing human monoclonal antibodies to severe acute respiratory syndrome coronavirus: target, mechanism of action, and therapeutic potential

(2011) Melissa M. Coughlin et al.   REVIEWS IN MEDICAL VIROLOGY

Antibody Responses in Mice Stimulated by Various Doses of the Potato-Derived Major Surface Antigen of Hepatitis B Virus

(2010) J. W. Youm et al.   Clinical and Vaccine Immunology