标题
Two-Faced: Roles of JNK Signalling During Tumourigenesis in the Drosophila Model
作者
关键词
-
出版物
Frontiers in Cell and Developmental Biology
Volume 8, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2020-02-05
DOI
10.3389/fcell.2020.00042
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Ask1 and Akt act synergistically to promote ROS-dependent regeneration in Drosophila
- (2019) Paula Santabárbara-Ruiz et al. PLoS Genetics
- Wingless modulates activator protein-1-mediated tumor invasion
- (2019) Shiping Zhang et al. ONCOGENE
- JNK signaling in cancer cell survival
- (2019) Qinghua Wu et al. MEDICINAL RESEARCH REVIEWS
- Lic regulates JNK-mediated cell death in Drosophila
- (2019) Yihao Sun et al. CELL PROLIFERATION
- Drosophila jumu modulates apoptosis via a JNK-dependent pathway and is required for other processes in wing development
- (2019) Xiao Chun Wang et al. APOPTOSIS
- Elimination of oncogenic cells that regulate epithelial homeostasis in Drosophila
- (2019) Shizue Ohsawa DEVELOPMENT GROWTH & DIFFERENTIATION
- Oncogenic Notch Triggers Neoplastic Tumorigenesis in a Transition-Zone-like Tissue Microenvironment
- (2019) Sheng-An Yang et al. DEVELOPMENTAL CELL
- Modeling Cancer with Flies and Fish
- (2019) Ross L. Cagan et al. DEVELOPMENTAL CELL
- Integrated computational and Drosophila cancer model platform captures previously unappreciated chemicals perturbing a kinase network
- (2019) Peter M. U. Ung et al. PLoS Computational Biology
- JNK-dependent cell cycle stalling in G2 promotes survival and senescence-like phenotypes in tissue stress
- (2019) Andrea Cosolo et al. eLife
- Role of D-GADD45 in JNK-Dependent Apoptosis and Regeneration in Drosophila
- (2019) Carlos Camilleri-Robles et al. Genes
- A personalized platform identifies trametinib plus zoledronate for a patient with KRAS-mutant metastatic colorectal cancer
- (2019) Erdem Bangi et al. Science Advances
- Strip and Cka negatively regulate JNK signalling during Drosophila spermatogenesis
- (2019) John E. La Marca et al. DEVELOPMENT
- Dynamic MAPK signaling activity underlies a transition from growth arrest to proliferation in Drosophila scribble mutant tumors
- (2019) Tiantian Ji et al. Disease Models & Mechanisms
- The antimicrobial peptide defensin cooperates with tumour necrosis factor to drive tumour cell death in Drosophila
- (2019) Jean-Philippe Parvy et al. eLife
- Characterization of TNF-induced cell death in Drosophila reveals caspase- and JNK-dependent necrosis and its role in tumor suppression
- (2019) Mingli Li et al. Cell Death & Disease
- Glioblastoma cells vampirize WNT from neurons and trigger a JNK/MMP signaling loop that enhances glioblastoma progression and neurodegeneration
- (2019) Marta Portela et al. PLOS BIOLOGY
- Tankyrase regulates apoptosis by activating JNK signaling in Drosophila
- (2018) Ying Feng et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Deltex interacts with Eiger and consequently influences the cell death in Drosophila melanogaster
- (2018) Debdeep Dutta et al. CELLULAR SIGNALLING
- Serpin Facilitates Tumor-Suppressive Cell Competition by Blocking Toll-Mediated Yki Activation in Drosophila
- (2018) Mitsuko Katsukawa et al. CURRENT BIOLOGY
- A Drosophila Tumor Suppressor Gene Prevents Tonic TNF Signaling through Receptor N-Glycosylation
- (2018) Geert de Vreede et al. DEVELOPMENTAL CELL
- Advances in Engineering the Fly Genome with the CRISPR-Cas System
- (2018) Ethan Bier et al. GENETICS
- Src Cooperates with Oncogenic Ras in Tumourigenesis via the JNK and PI3K Pathways in Drosophila epithelial Tissue
- (2018) Carole Poon et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Drosophila bendless catalyzes K63-linked polyubiquitination and is involved in the response to DNA damage
- (2018) Zhiqiang Bai et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- A whole-animal platform to advance a clinical kinase inhibitor into new disease space
- (2018) Masahiro Sonoshita et al. Nature Chemical Biology
- JNK and Yorkie drive tumor progression by generating polyploid giant cells in Drosophila
- (2018) Bojie Cong et al. ONCOGENE
- Short-term activation of the Jun N-terminal kinase pathway in apoptosis-deficient cells of Drosophila induces tumorigenesis
- (2018) Noelia Pinal et al. Nature Communications
- Yorkie and JNK Control Tumorigenesis in Drosophila Cells with Cytokinesis Failure
- (2018) Stephan U. Gerlach et al. Cell Reports
- Signalling crosstalk during early tumorigenesis in the absence of Polycomb silencing
- (2018) Jorge V. Beira et al. PLoS Genetics
- Modelling Cooperative Tumorigenesis in Drosophila
- (2018) Helena E. Richardson et al. Biomed Research International
- Advances in Engineering the Fly Genome with the CRISPR-Cas System
- (2018) Ethan Bier et al. GENETICS
- The Hippo Signaling Network and its Biological Functions
- (2018) Jyoti R. Misra et al. Annual Review of Genetics
- Chromosomal Instability Induces Cellular Invasion in Epithelial Tissues
- (2018) Najate Benhra et al. DEVELOPMENTAL CELL
- Polarity protein Canoe mediates overproliferation via modulation of JNK, Ras-MAPK and Hippo signalling
- (2018) Zhiwei Ma et al. CELL PROLIFERATION
- Epithelial cells release adenosine to promote local TNF production in response to polarity disruption
- (2018) Ingrid Poernbacher et al. Nature Communications
- The ligand Sas and its receptor PTP10D drive tumour-suppressive cell competition
- (2017) Masatoshi Yamamoto et al. NATURE
- Hippo signaling promotes JNK-dependent cell migration
- (2017) Xianjue Ma et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Feedback amplification loop drives malignant growth in epithelial tissues
- (2017) Mariana Muzzopappa et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Drosophila Duox maturation factor is a key component of a positive feedback loop that sustains regeneration signaling
- (2017) Sumbul Jawed Khan et al. PLoS Genetics
- Tumor-promoting function of apoptotic caspases by an amplification loop involving ROS, macrophages and JNK in Drosophila
- (2017) Ernesto Pérez et al. eLife
- JNK, p38, ERK, and SGK1 Inhibitors in Cancer
- (2017) Jonas Cicenas et al. Cancers
- GLYAT regulates JNK-mediated cell death in Drosophila
- (2017) Pu Ren et al. Scientific Reports
- An Ectopic Network of Transcription Factors Regulated by Hippo Signaling Drives Growth and Invasion of a Malignant Tumor Model
- (2016) Mardelle Atkins et al. CURRENT BIOLOGY
- Slit-Robo Repulsive Signaling Extrudes Tumorigenic Cells from Epithelia
- (2016) John Vaughen et al. DEVELOPMENTAL CELL
- Functional exploration of colorectal cancer genomes using Drosophila
- (2016) Erdem Bangi et al. Nature Communications
- Localized JNK signaling regulates organ size during development
- (2016) Helen Rankin Willsey et al. eLife
- In vivo genetic dissection of tumor growth and the Warburg effect
- (2016) Cheng-Wei Wang et al. eLife
- JNK signaling is converted from anti- to pro-tumor pathway by Ras-mediated switch of Warts activity
- (2015) Masato Enomoto et al. DEVELOPMENTAL BIOLOGY
- Interplay amongDrosophilatranscription factors Ets21c, Fos and Ftz-F1 drives JNK-mediated tumor malignancy
- (2015) Eva Külshammer et al. Disease Models & Mechanisms
- The Drosophila TNF receptor Grindelwald couples loss of cell polarity and neoplastic growth
- (2015) Ditte S. Andersen et al. NATURE
- Rho1–Wnd signaling regulates loss-of-cell polarity-induced cell invasion in Drosophila
- (2015) X Ma et al. ONCOGENE
- Impaired Hippo signaling promotes Rho1–JNK-dependent growth
- (2015) Xianjue Ma et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The transcription cofactor c-JUN mediates phenotype switching and BRAF inhibitor resistance in melanoma
- (2015) Rachel Ramsdale et al. Science Signaling
- Wallenda regulates JNK-mediated cell death in Drosophila
- (2015) X Ma et al. Cell Death & Disease
- Active JNK-dependent secretion of Drosophila Tyrosyl-tRNA synthetase by loser cells recruits haemocytes during cell competition
- (2015) Sergio Casas-Tintó et al. Nature Communications
- Toll pathway modulates TNF-induced JNK-dependent cell death inDrosophila
- (2015) Chenxi Wu et al. Open Biology
- The transcriptional response to tumorigenic polarity loss in Drosophila
- (2015) Brandon D Bunker et al. eLife
- The transcription cofactor c-JUN mediates phenotype switching and BRAF inhibitor resistance in melanoma
- (2015) Rachel Ramsdale et al. Science Signaling
- BTB-Zinc Finger Oncogenes Are Required for Ras and Notch-Driven Tumorigenesis in Drosophila
- (2015) Karen Doggett et al. PLoS One
- Recent Progress in the Design, Study, and Development of c-Jun N-Terminal Kinase Inhibitors as Anticancer Agents
- (2014) Abdellah Messoussi et al. CHEMISTRY & BIOLOGY
- Loss of Rab5 drives non-autonomous cell proliferation through TNF and Ras signaling in Drosophila
- (2014) Kyoko Takino et al. DEVELOPMENTAL BIOLOGY
- The Dpp/TGFβ-Dependent Corepressor Schnurri Protects Epithelial Cells from JNK-Induced Apoptosis in Drosophila Embryos
- (2014) Jorge V. Beira et al. DEVELOPMENTAL CELL
- The Drosophila TNF ortholog Eiger: Emerging physiological roles and evolution of the TNF system
- (2014) Tatsushi Igaki et al. SEMINARS IN IMMUNOLOGY
- Mitochondrial defects trigger proliferation of neighbouring cells via a senescence-associated secretory phenotype in Drosophila
- (2014) Mai Nakamura et al. Nature Communications
- A Functional Screen Reveals an Extensive Layer of Transcriptional and Splicing Control Underlying RAS/MAPK Signaling in Drosophila
- (2014) Dariel Ashton-Beaucage et al. PLOS BIOLOGY
- dUev1a modulates TNF-JNK mediated tumor progression and cell death in Drosophila
- (2013) Xianjue Ma et al. DEVELOPMENTAL BIOLOGY
- In Drosophila, RhoGEF2 cooperates with activated Ras in tumorigenesis through a pathway involving Rho1-Rok-Myosin-II and JNK signalling
- (2013) P. Khoo et al. Disease Models & Mechanisms
- Elevated expression of the V-ATPase C subunit triggers JNK-dependent cell invasion and overgrowth in a Drosophila epithelium
- (2013) A. G. Petzoldt et al. Disease Models & Mechanisms
- Caspase signalling in the absence of apoptosis drives Jnk-dependent invasion
- (2013) Vivek A Rudrapatna et al. EMBO REPORTS
- A Jnk–Rho–Actin remodeling positive feedback network directs Src-driven invasion
- (2013) V A Rudrapatna et al. ONCOGENE
- De-Regulation of JNK and JAK/STAT Signaling in ESCRT-II Mutant Tissues Cooperatively Contributes to Neoplastic Tumorigenesis
- (2013) Sarah E. Woodfield et al. PLoS One
- Ajuba Family Proteins Link JNK to Hippo Signaling
- (2013) G. Sun et al. Science Signaling
- Src42A modulates tumor invasion and cell death via Ben/dUev1a-mediated JNK activation in Drosophila
- (2013) X Ma et al. Cell Death & Disease
- Apoptotic cells can induce non-autonomous apoptosis through the TNF pathway
- (2013) Ainhoa Pérez-Garijo et al. eLife
- Src controls tumorigenesis via JNK-dependent regulation of the Hippo pathway in Drosophila
- (2012) Masato Enomoto et al. EMBO REPORTS
- Regulating cell morphogenesis: The drosophila jun N-terminal kinase pathway
- (2012) Luis Daniel Ríos-Barrera et al. GENESIS
- The actin cross-linker Filamin/Cheerio mediates tumor malignancy downstream of JNK signaling
- (2012) E. Kulshammer et al. JOURNAL OF CELL SCIENCE
- The Kelch Repeat Protein KLHDC10 Regulates Oxidative Stress-Induced ASK1 Activation by Suppressing PP5
- (2012) Yusuke Sekine et al. MOLECULAR CELL
- Mitochondrial defect drives non-autonomous tumour progression through Hippo signalling in Drosophila
- (2012) Shizue Ohsawa et al. NATURE
- Chemical genetic discovery of targets and anti-targets for cancer polypharmacology
- (2012) Arvin C. Dar et al. NATURE
- Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma
- (2012) Michael Krauthammer et al. NATURE GENETICS
- Group choreography: mechanisms orchestrating the collective movement of border cells
- (2012) Denise J. Montell et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- A non-cell-autonomous tumor suppressor role for Stat in eliminating oncogenic scribble cells
- (2012) M C Schroeder et al. ONCOGENE
- PAK1-dependent MAPK pathway activation is required for colorectal cancer cell proliferation
- (2012) Haitao Qing et al. TUMOR BIOLOGY
- The Apical Polarity Protein Network in Drosophila Epithelial Cells: Regulation of Polarity, Junctions, Morphogenesis, Cell Growth, and Survival
- (2011) Ulrich Tepass Annual Review of Cell and Developmental Biology
- Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signaling
- (2011) Karen Doggett et al. BMC DEVELOPMENTAL BIOLOGY
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- A dp53/JNK-dependant feedback amplification loop is essential for the apoptotic response to stress in Drosophila
- (2011) E Shlevkov et al. CELL DEATH AND DIFFERENTIATION
- Elimination of Oncogenic Neighbors by JNK-Mediated Engulfment in Drosophila
- (2011) Shizue Ohsawa et al. DEVELOPMENTAL CELL
- Identification of Novel Ras-Cooperating Oncogenes inDrosophila melanogaster: A RhoGEF/Rho-Family/JNK Pathway Is a Central Driver of Tumorigenesis
- (2011) Anthony M. Brumby et al. GENETICS
- Tumor suppression by cell competition through regulation of the Hippo pathway
- (2011) C.-L. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The lethal giant larvae tumour suppressor mutation requires dMyc oncoprotein to promote clonal malignancy
- (2010) Francesca Froldi et al. BMC BIOLOGY
- The dark side of fly TNF
- (2010) Marcos Vidal CELL CYCLE
- Lgl, the SWH pathway and tumorigenesis: It’s a matter of context and competition!
- (2010) Nicola A Grzeschik et al. CELL CYCLE
- Regulation of Hippo signaling by Jun kinase signaling during compensatory cell proliferation and regeneration, and in neoplastic tumors
- (2010) Gongping Sun et al. DEVELOPMENTAL BIOLOGY
- Oncogenic Ras Diverts a Host TNF Tumor Suppressor Activity into Tumor Promoter
- (2010) Julia B. Cordero et al. DEVELOPMENTAL CELL
- A Targeted UAS-RNAi Screen in Drosophila Larvae Identifies Wound Closure Genes Regulating Distinct Cellular Processes
- (2010) C. Lesch et al. GENETICS
- Rho1 regulates apoptosis via activation of the JNK signaling pathway at the plasma membrane
- (2010) Amanda L. Neisch et al. JOURNAL OF CELL BIOLOGY
- Regulation of mixed-lineage kinase activation in JNK-dependent morphogenesis
- (2010) R. A. Garlena et al. JOURNAL OF CELL SCIENCE
- Interaction between Ras V12 and scribbled clones induces tumour growth and invasion
- (2010) Ming Wu et al. NATURE
- A tumor-suppressing mechanism in Drosophila involving cell competition and the Hippo pathway
- (2010) J. Menendez et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In vivo RNAi: Today and Tomorrow
- (2010) N. Perrimon et al. Cold Spring Harbor Perspectives in Biology
- Involvement of Lgl and Mahjong/VprBP in Cell Competition
- (2010) Yoichiro Tamori et al. PLOS BIOLOGY
- scribble mutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs
- (2009) Gregory R Leong et al. BMC BIOLOGY
- Intrinsic Tumor Suppression and Epithelial Maintenance by Endocytic Activation of Eiger/TNF Signaling in Drosophila
- (2009) Tatsushi Igaki et al. DEVELOPMENTAL CELL
- Apoptosis in Drosophila: compensatory proliferation and undead cells
- (2009) Francisco A. Martin et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
- A Drosophila Model for EGFR-Ras and PI3K-Dependent Human Glioma
- (2009) Renee D. Read et al. PLoS Genetics
- A Quantitative RNAi Screen for JNK Modifiers Identifies Pvr as a Novel Regulator of Drosophila Immune Signaling
- (2009) David Bond et al. PLoS Pathogens
- Regulation of Cell Adhesion and Collective Cell Migration by Hindsight and Its Human Homolog RREB1
- (2008) Mariana Melani et al. CURRENT BIOLOGY
- JNK Signaling Controls Border Cell Cluster Integrity and Collective Cell Migration
- (2008) Flora Llense et al. CURRENT BIOLOGY
- An innate immune response of blood cells to tumors and tissue damage in Drosophila
- (2008) J. C. Pastor-Pareja et al. Disease Models & Mechanisms
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now