标题
Functional exploration of colorectal cancer genomes using Drosophila
作者
关键词
-
出版物
Nature Communications
Volume 7, Issue -, Pages 13615
出版商
Springer Nature
发表日期
2016-11-29
DOI
10.1038/ncomms13615
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Selumetinib with and without erlotinib in KRAS mutant and KRAS wild-type advanced nonsmall-cell lung cancer
- (2016) C. A. Carter et al. ANNALS OF ONCOLOGY
- Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients
- (2015) Marc van de Wetering et al. CELL
- Patient-centric trials for therapeutic development in precision oncology
- (2015) Andrew V. Biankin et al. NATURE
- Sequential cancer mutations in cultured human intestinal stem cells
- (2015) Jarno Drost et al. NATURE
- Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases
- (2015) Fleur Weeber et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Picking the Point of Inhibition: A Comparative Review of PI3K/AKT/mTOR Pathway Inhibitors
- (2014) R. Dienstmann et al. MOLECULAR CANCER THERAPEUTICS
- Clinical development success rates for investigational drugs
- (2014) Michael Hay et al. NATURE BIOTECHNOLOGY
- Quantifying Drosophila food intake: comparative analysis of current methodology
- (2014) Sonali A Deshpande et al. NATURE METHODS
- Bringing target-matched PI3King from the bench to the clinic
- (2013) Filip Janku CELL CYCLE
- Personalizing Oncology: Perspectives and Prospects
- (2013) John Mendelsohn JOURNAL OF CLINICAL ONCOLOGY
- MEK162 for patients with advanced melanoma harbouring NRAS or Val600 BRAF mutations: a non-randomised, open-label phase 2 study
- (2013) Paolo A Ascierto et al. LANCET ONCOLOGY
- Target-Based Therapeutic Matching in Early-Phase Clinical Trials in Patients with Advanced Colorectal Cancer and PIK3CA Mutations
- (2013) P. Ganesan et al. MOLECULAR CANCER THERAPEUTICS
- Development of PI3K inhibitors: lessons learned from early clinical trials
- (2013) Jordi Rodon et al. Nature Reviews Clinical Oncology
- Cancer Genome Landscapes
- (2013) B. Vogelstein et al. SCIENCE
- Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
- (2013) J. Gao et al. Science Signaling
- mTOR Signaling in Growth Control and Disease
- (2012) Mathieu Laplante et al. CELL
- Immune response to bacteria induces dissemination of Ras-activated Drosophila hindgut cells
- (2012) Erdem Bangi et al. EMBO REPORTS
- Chemical genetic discovery of targets and anti-targets for cancer polypharmacology
- (2012) Arvin C. Dar et al. NATURE
- Small molecule-induced cytosolic activation of protein kinase Akt rescues ischemia-elicited neuronal death
- (2012) H. Jo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.
- (2012) Ethan Cerami et al. Cancer Discovery
- Recent advances in apoptosis, mitochondria and drug resistance in cancer cells
- (2011) Inthrani R. Indran et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Inhibition of activated receptor tyrosine kinases by Sunitinib induces growth arrest and sensitizes melanoma cells to Bortezomib by blocking Akt pathway
- (2011) Andree Yeramian et al. INTERNATIONAL JOURNAL OF CANCER
- Antitumor activity and drug interactions of proteasome inhibitor Bortezomib in human high-risk myelodysplastic syndrome cells
- (2011) Jian Huang et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- mTOR Complex 2 Targets Akt for Proteasomal Degradation via Phosphorylation at the Hydrophobic Motif
- (2011) You-Tong Wu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- How Genetically Engineered Mouse Tumor Models Provide Insights Into Human Cancers
- (2011) Katerina Politi et al. JOURNAL OF CLINICAL ONCOLOGY
- Bortezomib represses HIF-1α protein expression and nuclear accumulation by inhibiting both PI3K/Akt/TOR and MAPK pathways in prostate cancer cells
- (2011) Christina D. Befani et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Uncoupling p53 Functions in Radiation-Induced Intestinal Damage via PUMA and p21
- (2011) B. J. Leibowitz et al. MOLECULAR CANCER RESEARCH
- PIK3CA Mutations in Patients with Advanced Cancers Treated with PI3K/AKT/mTOR Axis Inhibitors
- (2011) F. Janku et al. MOLECULAR CANCER THERAPEUTICS
- Advances in the preclinical testing of cancer therapeutic hypotheses
- (2011) Giordano Caponigro et al. NATURE REVIEWS DRUG DISCOVERY
- Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation
- (2011) Paul B. Chapman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Exploring the Genomes of Cancer Cells: Progress and Promise
- (2011) M. R. Stratton SCIENCE
- Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
- (2010) Kai Kessenbrock et al. CELL
- A Distinctive DNA Damage Response in Human Hematopoietic Stem Cells Reveals an Apoptosis-Independent Role for p53 in Self-Renewal
- (2010) Michael Milyavsky et al. Cell Stem Cell
- FoxOs Inhibit mTORC1 and Activate Akt by Inducing the Expression of Sestrin3 and Rictor
- (2010) Chia-Chen Chen et al. DEVELOPMENTAL CELL
- Deregulation of the PI3K and KRAS signaling pathways in human cancer cells determines their response to everolimus
- (2010) Federica Di Nicolantonio et al. JOURNAL OF CLINICAL INVESTIGATION
- Preclinical development of molecular-targeted agents for cancer
- (2010) Alberto Ocana et al. Nature Reviews Clinical Oncology
- PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor-positive breast cancer
- (2010) S. Loi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sestrin as a Feedback Inhibitor of TOR That Prevents Age-Related Pathologies
- (2010) J. H. Lee et al. SCIENCE
- Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
- (2009) Toshiro Sato et al. NATURE
- Characterization of the interface between normal and transformed epithelial cells
- (2009) Catherine Hogan et al. NATURE CELL BIOLOGY
- Molecular Basis of Colorectal Cancer
- (2009) Sanford D. Markowitz et al. NEW ENGLAND JOURNAL OF MEDICINE
- Gefitinib or Carboplatin–Paclitaxel in Pulmonary Adenocarcinoma
- (2009) Tony S. Mok et al. NEW ENGLAND JOURNAL OF MEDICINE
- Drug development in advanced colorectal cancer: Challenges and opportunities
- (2009) Robin K. Kelley et al. Current Oncology Reports
- Mutations in the Phosphatidylinositol-3-Kinase Pathway Predict for Antitumor Activity of the Inhibitor PX-866 whereas Oncogenic Ras Is a Dominant Predictor for Resistance
- (2008) N. T. Ihle et al. CANCER RESEARCH
- The behaviour of Drosophila adult hindgut stem cells is controlled by Wnt and Hh signalling
- (2008) Shigeo Takashima et al. NATURE
- Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers
- (2008) R. J. Leary et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started