标题
Asparagine Synthetase in Cancer: Beyond Acute Lymphoblastic Leukemia
作者
关键词
-
出版物
Frontiers in Oncology
Volume 9, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2020-01-09
DOI
10.3389/fonc.2019.01480
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- SOX12 promotes colorectal cancer cell proliferation and metastasis by regulating asparagine synthesis
- (2019) Feng Du et al. Cell Death & Disease
- The landscape of cancer cell line metabolism
- (2019) Haoxin Li et al. NATURE MEDICINE
- An Antitumor Bis(N-Heterocyclic Carbene)Platinum(II) Complex That Engages Asparagine Synthetase as an Anticancer Target
- (2019) Di Hu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Molecular diagnosis of asparagine synthetase (ASNS) deficiency in two Indian families and literature review of 29 ASNS deficient cases
- (2019) Akella Radha Rama Devi et al. GENE
- Glutaminase activity of L-asparaginase contributes to durable preclinical activity against acute lymphoblastic leukemia
- (2019) Wai Kin Chan et al. MOLECULAR CANCER THERAPEUTICS
- ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression
- (2019) Feven Tameire et al. NATURE CELL BIOLOGY
- Amino acid metabolism in hematologic malignancies and the era of targeted therapy
- (2019) Yoko Tabe et al. BLOOD
- SLC 1A3 contributes to L‐asparaginase resistance in solid tumors
- (2019) Jianhui Sun et al. EMBO JOURNAL
- Promoter demethylation of the asparagine synthetase gene is required for ATF4-dependent adaptation to asparagine depletion
- (2019) Jie Jiang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Translational reprogramming marks adaptation to asparagine restriction in cancer
- (2019) Gaurav Pathria et al. NATURE CELL BIOLOGY
- Autophagic Reliance Promotes Metabolic Reprogramming in Oncogenic KRAS-driven Tumorigenesis
- (2018) H. Helen Lin et al. Autophagy
- Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase
- (2018) Dana M. Gwinn et al. CANCER CELL
- Oligodendroglioma Cells Lack Glutamine Synthetase and Are Auxotrophic for Glutamine, but Do not Depend on Glutamine Anaplerosis for Growth
- (2018) Martina Chiu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Asparagine bioavailability governs metastasis in a model of breast cancer
- (2018) Simon R. V. Knott et al. NATURE
- Aspartate is an endogenous metabolic limitation for tumour growth
- (2018) Lucas B. Sullivan et al. NATURE CELL BIOLOGY
- Treatment and biology of pediatric acute lymphoblastic leukemia
- (2018) Motohiro Kato et al. PEDIATRICS INTERNATIONAL
- Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting
- (2018) H. Furkan Alkan et al. Cell Metabolism
- Asparagine synthetase expression is associated with the sensitivity to asparaginase in extranodal natural killer/T-cell lymphoma in vivo and in vitro
- (2018) Wen-jian Liu et al. OncoTargets and Therapy
- L-Asparaginase for newly diagnosed extra-nodal NK/T-cell lymphoma: systematic review and meta-analysis
- (2017) Vadim S. Pokrovsky et al. Expert Review of Anticancer Therapy
- Asparagine synthetase: Function, structure, and role in disease
- (2017) Carrie L. Lomelino et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The diagnosis and management of NK/T-cell lymphomas
- (2017) Eric Tse et al. Journal of Hematology & Oncology
- Asparaginase activity levels and monitoring in patients with acute lymphoblastic leukemia
- (2017) Wanda Salzer et al. LEUKEMIA & LYMPHOMA
- Asparagine Synthetase deficiency-report of a novel mutation and review of literature
- (2017) Neerja Gupta et al. METABOLIC BRAIN DISEASE
- Identification of a cytogenetic and molecular subgroup of acute myeloid leukemias showing sensitivity to L-Asparaginase
- (2017) Salvatore Nicola Bertuccio et al. Oncotarget
- Angiogenesis revisited from a metabolic perspective: role and therapeutic implications of endothelial cell metabolism
- (2017) Nihed Draoui et al. Open Biology
- Dependence on glutamine uptake and glutamine addiction characterize myeloma cells: a new attractive target
- (2016) M. Bolzoni et al. BLOOD
- Loss of asparagine synthetase suppresses the growth of human lung cancer cells by arresting cell cycle at G0/G1 phase
- (2016) Yi Xu et al. CANCER GENE THERAPY
- Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin
- (2016) Dan Y. Gui et al. Cell Metabolism
- SLC25A22 Promotes Proliferation and Survival of Colorectal Cancer Cells With KRAS Mutations and Xenograft Tumor Progression in Mice via Intracellular Synthesis of Aspartate
- (2016) Chi Chun Wong et al. GASTROENTEROLOGY
- Tumour-specific proline vulnerability uncovered by differential ribosome codon reading
- (2016) Fabricio Loayza-Puch et al. NATURE
- Arginine dependence of tumor cells: targeting a chink in cancer’s armor
- (2016) M D Patil et al. ONCOGENE
- Knockdown of asparagine synthetase (ASNS) suppresses cell proliferation and inhibits tumor growth in gastric cancer cells
- (2016) Qingxiang Yu et al. SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
- Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor
- (2016) Abigail S. Krall et al. Nature Communications
- Metabolic Alterations Caused by KRAS Mutations in Colorectal Cancer Contribute to Cell Adaptation to Glutamine Depletion by Upregulation of Asparagine Synthetase
- (2016) Kosuke Toda et al. NEOPLASIA
- Knockdown of asparagine synthetase by RNAi suppresses cell growth in human melanoma cells and epidermoid carcinoma cells
- (2015) Hui Li et al. BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY
- Targeting cancer cell metabolism in pancreatic adenocarcinoma
- (2015) Romain Cohen et al. Oncotarget
- The glutaminase activity of L-asparaginase is not required for anticancer activity against ASNS-negative cells
- (2014) W. K. Chan et al. BLOOD
- Asparaginase in the treatment of non-ALL hematologic malignancies
- (2014) Ashkan Emadi et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Down-Regulation of Asparagine Synthetase Induces Cell Cycle Arrest and Inhibits Cell Proliferation of Breast Cancer
- (2014) Hongjian Yang et al. Chemical Biology & Drug Design
- A novel genome-wide in vivo screen for metastatic suppressors in human colon cancer identifies the positive WNT-TCF pathway modulators TMED3 and SOX12
- (2014) A. Duquet et al. EMBO Molecular Medicine
- Asparagine Plays a Critical Role in Regulating Cellular Adaptation to Glutamine Depletion
- (2014) Ji Zhang et al. MOLECULAR CELL
- Asparagine synthetase expression and its potential prognostic value in patients with NK/T cell lymphoma
- (2014) YAQING LI et al. ONCOLOGY REPORTS
- Deficiency in asparagine synthetase expression in rectal cancers receiving concurrent chemoradiotherapy: negative prognostic impact and therapeutic relevance
- (2014) Ching-Yih Lin et al. TUMOR BIOLOGY
- Asparagine synthetase: regulation by cell stress and involvement in tumor biology
- (2013) Mukundh N. Balasubramanian et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia
- (2013) L. Willems et al. BLOOD
- Asparagine synthetase is an independent predictor of surgical survival and a potential therapeutic target in hepatocellular carcinoma
- (2013) B Zhang et al. BRITISH JOURNAL OF CANCER
- Changes in the expression of the glutamate transporter EAAT3/EAAC1 in health and disease
- (2013) Massimiliano G. Bianchi et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The SLC1 high-affinity glutamate and neutral amino acid transporter family
- (2013) Yoshikatsu Kanai et al. MOLECULAR ASPECTS OF MEDICINE
- Overexpression of Asparagine Synthetase and Matrix Metalloproteinase 19 Confers Cisplatin Sensitivity in Nasopharyngeal Carcinoma Cells
- (2013) R.-Y. Liu et al. MOLECULAR CANCER THERAPEUTICS
- Deficiency of Asparagine Synthetase Causes Congenital Microcephaly and a Progressive Form of Encephalopathy
- (2013) Elizabeth K. Ruzzo et al. NEURON
- The SLC38 family of sodium–amino acid co-transporters
- (2013) Stefan Bröer PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- L-Asparaginase-Induced Pancreatic Injury is Associated with an Imbalance in Plasma Amino Acid Levels
- (2013) Kei Minowa et al. Drugs in research & development
- Integrative Molecular Profiling Reveals Asparagine Synthetase Is a Target in Castration-Resistant Prostate Cancer
- (2012) Kanishka Sircar et al. AMERICAN JOURNAL OF PATHOLOGY
- A sulfoximine-based inhibitor of human asparagine synthetase kills l-asparaginase-resistant leukemia cells
- (2012) Hideyuki Ikeuchi et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Pancreatic Tumor Sensitivity to Plasma L-Asparagine Starvation
- (2012) Emmanuelle Dufour et al. PANCREAS
- The Transcription Factor Network Associated With the Amino Acid Response in Mammalian Cells
- (2012) Michael S. Kilberg et al. Advances in Nutrition
- Expanding Targets for a Metabolic Therapy of Cancer: L-Asparaginase
- (2011) Daniele Covini et al. Recent Patents on Anti-Cancer Drug Discovery
- Circulating tumour cells demonstrate an altered response to hypoxia and an aggressive phenotype
- (2010) K Ameri et al. BRITISH JOURNAL OF CANCER
- The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation
- (2010) Jiangbin Ye et al. EMBO JOURNAL
- Effect of L-Asparaginase Combined with Vincristine and Prednisolone on Acute Myeloblastic Leukemia (M0) Associated with Non-Hodgkin Lymphoma
- (2009) Akira Horikoshi et al. ACTA HAEMATOLOGICA
- ATF4-dependent transcription mediates signaling of amino acid limitation
- (2009) Michael S. Kilberg et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Transcriptional induction of the human asparagine synthetase gene during the unfolded protein response does not require the ATF6 and IRE1/XBP1 arms of the pathway
- (2008) Altin Gjymishka et al. BIOCHEMICAL JOURNAL
- Asparagine synthetase is a predictive biomarker of l-asparaginase activity in ovarian cancer cell lines
- (2008) Philip L. Lorenzi et al. MOLECULAR CANCER THERAPEUTICS
- Correlation between asparaginase sensitivity and asparagine synthetase protein content, but not mRNA, in acute lymphoblastic leukemia cell lines
- (2007) Nan Su et al. PEDIATRIC BLOOD & CANCER
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search