Asparaginase in the treatment of non-ALL hematologic malignancies

Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia

(2013) L. Willems et al.   BLOOD

Epidemiology of cancer-associated venous thrombosis

(2013) J. F. Timp et al.   BLOOD

Asparagine synthetase is an independent predictor of surgical survival and a potential therapeutic target in hepatocellular carcinoma

(2013) B Zhang et al.   BRITISH JOURNAL OF CANCER

Inhibition of glutaminase selectively suppresses the growth of primary acute myeloid leukemia cells with IDH mutations

(2013) Ashkan Emadi et al.   EXPERIMENTAL HEMATOLOGY

Sequential administration of methotrexate and asparaginase in relapsed or refractory pediatric acute myeloid leukemia

(2013) Jassada Buaboonnam et al.   PEDIATRIC BLOOD & CANCER

Red Blood Cell-Encapsulated L-Asparaginase: Potential Therapy of Patients with Asparagine Synthetase Deficient Acute Myeloid Leukemia

(2013) Vaidehi Agrawal et al.   PROTEIN AND PEPTIDE LETTERS

Acute myeloid leukemia with mediastinal myeloid sarcoma refractory to acute myeloid leukemia therapy but responsive to l-asparaginase

(2012) Hiroyoshi Takahashi et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

A Study on L-Asparaginase ofNocardia levisMK-VL_113

(2012) Alapati Kavitha et al.   TheScientificWorldJOURNAL

L-Asparaginase and Inhibitors of Glutamine Synthetase Disclose Glutamine Addiction of β-Catenin-Mutated Human Hepatocellular Carcinoma Cells

(2011)   CURRENT CANCER DRUG TARGETS

Asparaginases

(2011) Vassilios I. Avramis   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Expanding Targets for a Metabolic Therapy of Cancer: L-Asparaginase

(2011) Daniele Covini et al.   Recent Patents on Anti-Cancer Drug Discovery

Rational engineering of L-asparaginase reveals importance of dual activity for cancer cell toxicity

(2010) M. N. Offman et al.   BLOOD

Efficacy of L-asparaginase with methotrexate and dexamethasone (AspaMetDex regimen) in patients with refractory or relapsing extranodal NK/T-cell lymphoma, a phase 2 study

(2010) A. Jaccard et al.   BLOOD

L-asparaginase treatment in acute lymphoblastic leukemia

(2010) Rob Pieters et al.   CANCER

Expression profiling after activation of amino acid deprivation response in HepG2 human hepatoma cells

(2010) Jixiu Shan et al.   PHYSIOLOGICAL GENOMICS

Cell-Cycle Inhibition by Helicobacter pylori L-Asparaginase

(2010) Claudia Scotti et al.   PLoS One

Diagnosis and management of natural killer-cell malignancies

(2010) Fumihiro Ishida et al.   Expert Review of Hematology

Structure ofHelicobacter pyloriL-asparaginase at 1.4 Å resolution

(2009) Prathusha Dhavala et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Effect of L-Asparaginase Combined with Vincristine and Prednisolone on Acute Myeloblastic Leukemia (M0) Associated with Non-Hodgkin Lymphoma

(2009) Akira Horikoshi et al.   ACTA HAEMATOLOGICA

Toward a Total Cure for Acute Lymphoblastic Leukemia

(2009) Ching-Hon Pui   JOURNAL OF CLINICAL ONCOLOGY

Helicobacter pyloril-asparaginase: A promising chemotherapeutic agent

(2008) Donata Cappelletti et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Asparagine synthetase is a predictive biomarker of l-asparaginase activity in ovarian cancer cell lines

(2008) Philip L. Lorenzi et al.   MOLECULAR CANCER THERAPEUTICS