标题
Repurposing Drugs for Acute Myeloid Leukemia: A Worthy Cause or a Futile Pursuit?
作者
关键词
-
出版物
Cancers
Volume 12, Issue 2, Pages 441
出版商
MDPI AG
发表日期
2020-02-24
DOI
10.3390/cancers12020441
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Drug repurposing in oncology: Compounds, pathways, phenotypes and computational approaches for colorectal cancer
- (2019) Patrycja Nowak-Sliwinska et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Mebendazole as a Candidate for Drug Repurposing in Oncology: An Extensive Review of Current Literature
- (2019) Guerini et al. Cancers
- The Antiarrhythmic Drug, Amiodarone, Decreases AKT Activity and Sensitizes Human Acute Myeloid Leukemia Cells to Apoptosis by ABT-263
- (2018) Corey J. Ketchem et al. AMERICAN JOURNAL OF THE MEDICAL SCIENCES
- Estimation of clinical trial success rates and related parameters
- (2018) Chi Heem Wong et al. BIOSTATISTICS
- Renovation as innovation: is repurposing the future of drug discovery research?
- (2018) Arthur Neuberger et al. DRUG DISCOVERY TODAY
- Leukemic stem cell signatures identify novel therapeutics targeting acute myeloid leukemia
- (2018) Isabelle Laverdière et al. Blood Cancer Journal
- Lysine-Specific Demethylase 1A as a Promising Target in Acute Myeloid Leukemia
- (2018) Daniela Magliulo et al. Frontiers in Oncology
- Drug repurposing: progress, challenges and recommendations
- (2018) Sudeep Pushpakom et al. NATURE REVIEWS DRUG DISCOVERY
- Targeting acute myeloid leukemia by drug-induced c-MYB degradation
- (2017) V Walf-Vorderwülbecke et al. LEUKEMIA
- Sertraline exerts its antitumor functions through both apoptosis and autophagy pathways in acute myeloid leukemia cells
- (2017) Di Xia et al. LEUKEMIA & LYMPHOMA
- Towards repositioning of quinacrine for treatment of acute myeloid leukemia – Promising synergies and in vivo effects
- (2017) Anna Eriksson et al. LEUKEMIA RESEARCH
- Dual role of autophagy in hallmarks of cancer
- (2017) Shikha Satendra Singh et al. ONCOGENE
- Drug repurposing in cancer
- (2017) Linda Sleire et al. PHARMACOLOGICAL RESEARCH
- Niclosamide suppresses acute myeloid leukemia cell proliferation through inhibition of CREB-dependent signaling pathways
- (2017) Hee-Don Chae et al. Oncotarget
- Adult Utilization of Psychiatric Drugs and Differences by Sex, Age, and Race
- (2017) Thomas J. Moore et al. JAMA Internal Medicine
- Giving Drugs a Second Chance: Overcoming Regulatory and Financial Hurdles in Repurposing Approved Drugs As Cancer Therapeutics
- (2017) J. Javier Hernandez et al. Frontiers in Oncology
- Evaluation of artemisinins for the treatment of acute myeloid leukemia
- (2016) Christina D. Drenberg et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Innovation in the pharmaceutical industry: New estimates of R&D costs
- (2016) Joseph A. DiMasi et al. JOURNAL OF HEALTH ECONOMICS
- Repositioning of bromocriptine for treatment of acute myeloid leukemia
- (2016) María Carmen Lara-Castillo et al. Journal of Translational Medicine
- Failure of Investigational Drugs in Late-Stage Clinical Development and Publication of Trial Results
- (2016) Thomas J. Hwang et al. JAMA Internal Medicine
- A Phase 1 study of intravenous infusions of tigecycline in patients with acute myeloid leukemia
- (2016) Gregory A. Reed et al. Cancer Medicine
- Idarubicin, cytarabine, and pravastatin as induction therapy for untreated acute myeloid leukemia and high-risk myelodysplastic syndrome
- (2015) Mazyar Shadman et al. AMERICAN JOURNAL OF HEMATOLOGY
- Induction of cytosine arabinoside-resistant human myeloid leukemia cell death through autophagy regulation by hydroxychloroquine
- (2015) Yundeok Kim et al. BIOMEDICINE & PHARMACOTHERAPY
- An update of current treatments for adult acute myeloid leukemia
- (2015) H. Dombret et al. BLOOD
- Pyrrole- and indole-containing tranylcypromine derivatives as novel lysine-specific demethylase 1 inhibitors active on cancer cells
- (2015) Veronica Rodriguez et al. MedChemComm
- Drug screen in patient cells suggests quinacrine to be repositioned for treatment of acute myeloid leukemia
- (2015) A Eriksson et al. Blood Cancer Journal
- Identification and validation of the dopamine agonist bromocriptine as a novel therapy for high-risk myelodysplastic syndromes and secondary acute myeloid leukemia
- (2015) Fabio Giuseppe Liberante et al. Oncotarget
- Pharmacologic Therapy of Diabetes and Overall Cancer Risk and Mortality: A Meta-Analysis of 265 Studies
- (2015) Lang Wu et al. Scientific Reports
- Statins use and the risk of all and subtype hematological malignancies: a meta-analysis of observational studies
- (2015) Danitza Pradelli et al. Cancer Medicine
- Phase 2 clinical trial of 5-azacitidine, valproic acid, and all-trans retinoic acid in patients with high-risk acute myeloid leukemia or myelodysplastic syndrome
- (2015) Oncotarget
- Valproic acid in combination with all-trans retinoic acid and intensive therapy for acute myeloid leukemia in older patients
- (2014) M. Tassara et al. BLOOD
- SWOG0919: a Phase 2 study of idarubicin and cytarabine in combination with pravastatin for relapsed acute myeloid leukaemia
- (2014) Anjali S. Advani et al. BRITISH JOURNAL OF HAEMATOLOGY
- Results of phase 2 randomized study of low-dose decitabine with or without valproic acid in patients with myelodysplastic syndrome and acute myelogenous leukemia
- (2014) Jean-Pierre Issa et al. CANCER
- The prognostic value of metformin for cancer patients with concurrent diabetes: a systematic review and meta-analysis
- (2014) Z.-J. Zhang et al. DIABETES OBESITY & METABOLISM
- A phase I trial of ribavirin and low-dose cytarabine for the treatment of relapsed and refractory acute myeloid leukemia with elevated eIF4E
- (2014) S. Assouline et al. HAEMATOLOGICA
- BCL-2 Inhibition Targets Oxidative Phosphorylation and Selectively Eradicates Quiescent Human Leukemia Stem Cells
- (2013) Eleni D. Lagadinou et al. Cell Stem Cell
- Valproic acid pathway
- (2013) Yogita Ghodke-Puranik et al. Pharmacogenetics and Genomics
- Histone demethylase Lsd1 represses hematopoietic stem and progenitor cell signatures during blood cell maturation
- (2013) Marc A Kerenyi et al. eLife
- The Histone Demethylase KDM1A Sustains the Oncogenic Potential of MLL-AF9 Leukemia Stem Cells
- (2012) William J. Harris et al. CANCER CELL
- Identification of Drugs Including a Dopamine Receptor Antagonist that Selectively Target Cancer Stem Cells
- (2012) Eleftherios Sachlos et al. CELL
- A Phase I Study of the Metal Ionophore Clioquinol in Patients With Advanced Hematologic Malignancies
- (2012) Aaron D. Schimmer et al. Clinical Lymphoma Myeloma & Leukemia
- Copper levels in patients with hematological malignancies
- (2012) Georgia D. Kaiafa et al. European Journal of Internal Medicine
- Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia
- (2012) Tino Schenk et al. NATURE MEDICINE
- Inhibition of Mitochondrial Translation as a Therapeutic Strategy for Human Acute Myeloid Leukemia
- (2011) Marko Škrtić et al. CANCER CELL
- Valproic acid combined with cytosine arabinoside in elderly patients with acute myeloid leukemia hasin vitrobut limited clinical activity
- (2011) Steven Lane et al. LEUKEMIA & LYMPHOMA
- Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE
- (2011) Peng Qiu et al. NATURE BIOTECHNOLOGY
- The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation
- (2010) A. S. Green et al. BLOOD
- The antiparasitic agent ivermectin induces chloride-dependent membrane hyperpolarization and cell death in leukemia cells
- (2010) S. Sharmeen et al. BLOOD
- Dihydroartemisinin induces apoptosis in HL-60 leukemia cells dependent of iron and p38 mitogen-activated protein kinase activation but independent of reactive oxygen species
- (2010) Jin-Jian Lu et al. CANCER BIOLOGY & THERAPY
- Antineoplastic Mechanisms of Niclosamide in Acute Myelogenous Leukemia Stem Cells: Inactivation of the NF- B Pathway and Generation of Reactive Oxygen Species
- (2010) Y. Jin et al. CANCER RESEARCH
- Toxicity of the antimalarial artemisinin and its dervatives
- (2010) Thomas Efferth et al. CRITICAL REVIEWS IN TOXICOLOGY
- Lysine Methylation Regulates E2F1-Induced Cell Death
- (2010) Haroula Kontaki et al. MOLECULAR CELL
- mTOR: from growth signal integration to cancer, diabetes and ageing
- (2010) Roberto Zoncu et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Identification of Niclosamide as a New Small-Molecule Inhibitor of the STAT3 Signaling Pathway
- (2010) Xiaomei Ren et al. ACS Medicinal Chemistry Letters
- The Anti-Helminthic Niclosamide Inhibits Wnt/Frizzled1 Signaling
- (2009) Minyong Chen et al. BIOCHEMISTRY
- Molecular targeting of the oncogene eIF4E in acute myeloid leukemia (AML): a proof-of-principle clinical trial with ribavirin
- (2009) S. Assouline et al. BLOOD
- Screen for Chemical Modulators of Autophagy Reveals Novel Therapeutic Inhibitors of mTORC1 Signaling
- (2009) Aruna D. Balgi et al. PLoS One
- Cardiac Glycosides Induce Cell Death in Human Cells by Inhibiting General Protein Synthesis
- (2009) Andrea Perne et al. PLoS One
- Chemical mechanisms of histone lysine and arginine modifications
- (2008) Brian C. Smith et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Twenty years of follow-up among survivors of childhood and young adult acute myeloid leukemia
- (2008) Daniel A. Mulrooney et al. CANCER
- Clioquinol inhibits the proteasome and displays preclinical activity in leukemia and myeloma
- (2008) X Mao et al. LEUKEMIA
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