The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation
出版年份 2010 全文链接
标题
The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation
作者
关键词
-
出版物
BLOOD
Volume 116, Issue 20, Pages 4262-4273
出版商
American Society of Hematology
发表日期
2010-07-29
DOI
10.1182/blood-2010-02-269837
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Targeting translation in acute myeloid leukemia: A new paradigm for therapy?
- (2011) Jerome Tamburini et al. CELL CYCLE
- Metformin, Independent of AMPK, Inhibits mTORC1 in a Rag GTPase-Dependent Manner
- (2010) Adem Kalender et al. Cell Metabolism
- Targeting iron homeostasis induces cellular differentiation and synergizes with differentiating agents in acute myeloid leukemia
- (2010) Celine Callens et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)
- (2009) Juan M. García-Martínez et al. BIOCHEMICAL JOURNAL
- Protein synthesis is resistant to rapamycin and constitutes a promising therapeutic target in acute myeloid leukemia
- (2009) J. Tamburini et al. BLOOD
- A Phase I Study of the Mammalian Target of Rapamycin Inhibitor Sirolimus and MEC Chemotherapy in Relapsed and Refractory Acute Myelogenous Leukemia
- (2009) A. E. Perl et al. CLINICAL CANCER RESEARCH
- Specific Activation of mTORC1 by Rheb G-proteinin VitroInvolves Enhanced Recruitment of Its Substrate Protein
- (2009) Tatsuhiro Sato et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- LKB1 and Mammalian Target of Rapamycin As Predictive Factors for the Anticancer Efficacy of Metformin
- (2009) Regan M. Memmott et al. JOURNAL OF CLINICAL ONCOLOGY
- Tumor Cell Metabolism: Cancer's Achilles' Heel
- (2008) Guido Kroemer et al. CANCER CELL
- Re-evaluating the Roles of Proposed Modulators of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling
- (2008) Xuemin Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Isolation of Hyperactive Mutants of Mammalian Target of Rapamycin
- (2008) Yoichiro Ohne et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PI-103, a dual inhibitor of Class IA phosphatidylinositide 3-kinase and mTOR, has antileukemic activity in AML
- (2008) S Park et al. LEUKEMIA
- The TSC-mTOR Pathway Mediates Translational Activation of TOP mRNAs by Insulin Largely in a Raptor- or Rictor-Independent Manner
- (2008) I. Patursky-Polischuk et al. MOLECULAR AND CELLULAR BIOLOGY
- AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint
- (2008) Dana M. Gwinn et al. MOLECULAR CELL
- LKB1; linking cell structure and tumor suppression
- (2008) A F Hezel et al. ONCOGENE
- The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level
- (2008) I Ben Sahra et al. ONCOGENE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started