Probing Sialidases or Siglecs with Sialic Acid Analogues, Clusters and Precursors

Multivalent Sialosides - A Tool to Explore the Role of Sialic Acids in Biological Processes

(2019) Raghavendra V. Kikkeri et al.   Chemistry-An Asian Journal

Structural Insights into Human Parainfluenza Virus 3 Hemagglutinin–Neuraminidase Using Unsaturated 3-N-Substituted Sialic Acids as Probes

(2018) Mauro Pascolutti et al.   ACS Chemical Biology

A tetravalent sialic acid-coated tetraphenylethene luminogen with aggregation-induced emission characteristics: design, synthesis and application for sialidase activity assay, high-throughput screening of sialidase inhibitors and diagnosis of bacterial vaginosis

(2018) Guang-jian Liu et al.   CHEMICAL COMMUNICATIONS

Viewing Siglecs through the lens of tumor immunology

(2017) Isabella Fraschilla et al.   IMMUNOLOGICAL REVIEWS

Fluorescent Neuraminidase Assay Based on Supramolecular Dye Capture After Enzymatic Cleavage

(2017) Wenqi Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silver nanoparticle plasmonic enhanced förster resonance energy transfer (FRET) imaging of protein-specific sialylation on the cell surface

(2017) Tingbi Zhao et al.   Nanoscale

Exploring inhibitor structural features required to engage the 216-loop of human parainfluenza virus type-3 hemagglutinin-neuraminidase

(2017) Ibrahim M. El-Deeb et al.   MedChemComm

Interaction of an Iridium(III) Complex with G-Quadruplex DNA and Its Application in Luminescent Switch-On Detection of Siglec-5

(2016) Sheng Lin et al.   ANALYTICAL CHEMISTRY

The Catalytic Mechanism of Human Parainfluenza Virus Type 3 Haemagglutinin-Neuraminidase Revealed

(2015) Larissa Dirr et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Electrochemical Assay to Detect Influenza Viruses and Measure Drug Susceptibility

(2015) Xiaohu Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and labeling of α-(2,9)-trisialic acid with cyanine dyes for imaging of glycan-binding receptors on living cells

(2015) Xiao-tai Zhang et al.   CHEMICAL COMMUNICATIONS

Cellular metabolism of unnatural sialic acid precursors

(2015) Nam D. Pham et al.   GLYCOCONJUGATE JOURNAL

The C-type Lectin Langerin Functions as a Receptor for Attachment and Infectious Entry of Influenza A Virus

(2015) Wy Ching Ng et al.   JOURNAL OF VIROLOGY

Targeting Siglecs with a sialic acid–decorated nanoparticle abrogates inflammation

(2015) Shaun Spence et al.   Science Translational Medicine

Tuning Mechanism-Based Inactivators of Neuraminidases: Mechanistic and Structural Insights

(2014) Sabrina Buchini et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Visualization of Sialidase Activity in Mammalian Tissues and Cancer Detection with a Novel Fluorescent Sialidase Substrate

(2014) Akira Minami et al.   PLoS One

Disubstituted sialic acid ligands targeting siglecs CD33 and CD22 associated with myeloid leukaemias and B cell lymphomas

(2014) Cory D. Rillahan et al.   Chemical Science

Structure-guided discovery of potent and dual-acting human parainfluenza virus haemagglutinin–neuraminidase inhibitors

(2014) Patrice Guillon et al.   Nature Communications

CD169-positive macrophages in regional lymph nodes are associated with a favorable prognosis in patients with colorectal carcinoma

(2013) Koji Ohnishi et al.   CANCER SCIENCE

Syntheses of 2-Deoxy-2,3-didehydro-N-acetylneuraminic Acid Analogues Modified by ^|^#945;-Acylaminoamido Groups at the C-4 Position Using Isocyanide-Based Four-Component Coupling and Biological Evaluation as Inhibitors of Human Parainfluenza Virus Type 1

(2013) Reiko Nishino et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

A Cis-Membrane FRET-Based Method for Protein-Specific Imaging of Cell-Surface Glycans

(2013) Wei Lin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cell-permeable probe for identification and imaging of sialidases

(2013) C.-S. Tsai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism-Based Covalent Neuraminidase Inhibitors with Broad-Spectrum Influenza Antiviral Activity

(2013) J.-H. Kim et al.   SCIENCE

Influenza neuraminidase operates via a nucleophilic mechanism and can be targeted by covalent inhibitors

(2013) Christopher J. Vavricka et al.   Nature Communications

Glycan-Targeted Virus-like Nanoparticles for Photodynamic Therapy

(2012) Jin-Kyu Rhee et al.   BIOMACROMOLECULES

Continuous Fluorometric Assay for Sialidase Activity and Inhibition with Conjugated Polyelectrolytes

(2012) Ya-juan Wang et al.   Chemistry-An Asian Journal

Mammalian sialidases: Physiological and pathological roles in cellular functions

(2012) T. Miyagi et al.   GLYCOBIOLOGY

Metabolism of Diazirine-ModifiedN-Acetylmannosamine Analogues to Photo-Cross-Linking Sialosides

(2011) Michelle R. Bond et al.   BIOCONJUGATE CHEMISTRY

Targeting B lymphoma with nanoparticles bearing glycan ligands of CD22

(2011) Weihsu C. Chen et al.   LEUKEMIA & LYMPHOMA

Development of tetraphenylethylene-based fluorescent oligosaccharide probes for detection of influenza virus

(2010) Tomohisa Kato et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

In vivo targeting of B-cell lymphoma with glycan ligands of CD22

(2010) W. C. Chen et al.   BLOOD

N-Linked Glycosylation Facilitates Sialic Acid-Independent Attachment and Entry of Influenza A Viruses into Cells Expressing DC-SIGN or L-SIGN

(2010) S. L. Londrigan et al.   JOURNAL OF VIROLOGY

Metabolically incorporated photocrosslinking sialic acid covalently captures a ganglioside–protein complex

(2010) Michelle R. Bond et al.   Molecular BioSystems

An evaluation of OSOM BV blue test in the diagnosis of bacterial vaginosis

(2010) Fatima Shujatullah et al.   Asian Pacific Journal of Tropical Medicine

Effect of Hemagglutinin-Neuraminidase Inhibitors BCX 2798 and BCX 2855 on Growth and Pathogenicity of Sendai/Human Parainfluenza Type 3 Chimera Virus in Mice

(2009) M. Watanabe et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Synthesis and Biological Evaluation of Non-Hydrolyzable 1,2,3-Triazole-Linked Sialic Acid Derivatives as Neuraminidase Inhibitors

(2009) Michel Weïwer et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Photocrosslinking of glycoconjugates using metabolically incorporated diazirine-containing sugars

(2009) Michelle R Bond et al.   Nature Protocols

Sialylated multivalent antigens engage CD22in transand inhibit B cell activation

(2009) Adam H. Courtney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Photoactivatable Crosslinking Sugars for Capturing Glycoprotein Interactions

(2008) Yoshihito Tanaka et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY