Article
Chemistry, Physical
Sidi Cheng, Yu Luo, Ting Yu, Jing Li, Chunfang Gan, Shuang Luo, Qiang Zhu
Summary: An unactivated alkene was successfully subjected to 1,2-difunctionalization through a palladium-catalyzed four-component cascade reaction, leading to the convenient synthesis of acetamides with various substituents and pyrrolo-fused heterocycles.
Article
Chemistry, Organic
Negin Dehghan, Hossein Nasr-Isfahani, Afshin Sarvary, Mohammad Bakherad
Summary: The study describes a double four component Azido-Ugi reaction involving isocyanide, TMSN3, aldehyde, and 4,4'-sulfonyldianiline with two amine functional groups in MeOH at 65 degrees C. It reports the synthesis of pharmacologically and structurally interesting compounds with two 1,5-disubstituted tetrazole rings from available and inexpensive reagents using a convenient process and mild reaction conditions. Modifications in the structure of the reaction product could be achieved by varying the aldehyde or isocyanide component, with the products being characterized by Mass, H-1 NMR, and C-13 NMR spectral studies as new.
JOURNAL OF HETEROCYCLIC CHEMISTRY
(2021)
Article
Physics, Particles & Fields
Kaushik Bhattacharya, Anirban Chatterjee, Saddam Hussain
Summary: In this paper, we investigate a non-minimal, space-time derivative dependent coupling between the k-essence field and a relativistic fluid using a variational approach. By introducing a coupling term at the Lagrangian level, we obtain the k-essence field equation and the Friedmann equations for a spatially flat Friedmann-Lemaitre-Robertson-Walker (FLRW) metric. Through dynamical analysis, we analyze the dynamics of this coupled scenario in the context of two interaction models, which can produce stable accelerating solutions and explain different phases of the evolutionary universe.
EUROPEAN PHYSICAL JOURNAL C
(2023)
Article
Chemistry, Organic
Xianghao Luo, Yibi Xie, Nianyu Huang, Long Wang
Summary: This paper reports a novel strategy of Ugi four-component and post-modification tandem reaction based on in-situ capture of isocyanide. This strategy solves the problems of isocyanide instability, high toxicity, and unfriendly environmental impact, and provides a green and pollution-free reaction strategy.
CHINESE JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Organic
Ali Aminkhani, Sina Sharifi
Summary: An efficient four-component reaction was described for the synthesis of pyrrolo[2,1-a]isoquinolines under solvent-free conditions. The reaction involved malononitrile, aromatic aldehydes, isoquinoline, and cyclohexyl isocyanide, and the domino Knoevenagel-nucleophilic cycloaddition reaction yielded the desired products in excellent yields in less than 1 h.
LETTERS IN ORGANIC CHEMISTRY
(2022)
